Carlos Conde
@carlos-conde.bsky.social
Cell Biologist at i3S studying chromosome segregation.
Assistant Professor at ICBAS-University of Porto.
Assistant Professor at ICBAS-University of Porto.
(2/16) BUT then things got interesting! Nelson found that we could RESCUE these mitotic defects by simply tethering MPS1 to the centrosomes (MPS1-CM2). No MPS1 at kinetochores, only at centrosomes, and the error correction seems to work just fine!
April 13, 2025 at 1:52 AM
(2/16) BUT then things got interesting! Nelson found that we could RESCUE these mitotic defects by simply tethering MPS1 to the centrosomes (MPS1-CM2). No MPS1 at kinetochores, only at centrosomes, and the error correction seems to work just fine!
(1/16) Nelson Leça, a PhD student in the lab, was exploring MPS1 roles across subcellular locations. He saw that depleting MPS1 in Drosophila cells increased the frequency of chromosomes erroneously attached to spindle microtubules and delayed chromosome congression. Nothing really new here...
April 13, 2025 at 1:52 AM
(1/16) Nelson Leça, a PhD student in the lab, was exploring MPS1 roles across subcellular locations. He saw that depleting MPS1 in Drosophila cells increased the frequency of chromosomes erroneously attached to spindle microtubules and delayed chromosome congression. Nothing really new here...