Ahmet O. Ceceli
@aoceceli.bsky.social
Instructor @ Mt. Sinai. Studying the neuroscience of addiction, reward, habits, and some related things with NIDA K99.
Reposted by Ahmet O. Ceceli
ManuscriptCentral Wrapped!
In 2025, you submitted 5 papers
AND all got rejected 🎉
You spent 💯 minutes in total trying to submit your papers!
You reviewed for 10 journals that would never publish your papers ❤️
In 2025, you submitted 5 papers
AND all got rejected 🎉
You spent 💯 minutes in total trying to submit your papers!
You reviewed for 10 journals that would never publish your papers ❤️
They should do MyChart Wrapped
December 3, 2025 at 11:40 PM
ManuscriptCentral Wrapped!
In 2025, you submitted 5 papers
AND all got rejected 🎉
You spent 💯 minutes in total trying to submit your papers!
You reviewed for 10 journals that would never publish your papers ❤️
In 2025, you submitted 5 papers
AND all got rejected 🎉
You spent 💯 minutes in total trying to submit your papers!
You reviewed for 10 journals that would never publish your papers ❤️
Reposted by Ahmet O. Ceceli
Cocaine Addiction Trinity
Three subtypes of cocaine use disorder and their neurobehavioral profiles
A ‘Relief Type’ with high negative emotionality
A ‘Cognitive Type’ with lower executive function
An ‘Undefined Type’ with no apparent impairments
www.nature.com/articles/s41...
Three subtypes of cocaine use disorder and their neurobehavioral profiles
A ‘Relief Type’ with high negative emotionality
A ‘Cognitive Type’ with lower executive function
An ‘Undefined Type’ with no apparent impairments
www.nature.com/articles/s41...
Subtypes of cocaine use disorder and their neurobehavioral profiles - Translational Psychiatry
Translational Psychiatry - Subtypes of cocaine use disorder and their neurobehavioral profiles
www.nature.com
December 4, 2025 at 4:31 PM
Cocaine Addiction Trinity
Three subtypes of cocaine use disorder and their neurobehavioral profiles
A ‘Relief Type’ with high negative emotionality
A ‘Cognitive Type’ with lower executive function
An ‘Undefined Type’ with no apparent impairments
www.nature.com/articles/s41...
Three subtypes of cocaine use disorder and their neurobehavioral profiles
A ‘Relief Type’ with high negative emotionality
A ‘Cognitive Type’ with lower executive function
An ‘Undefined Type’ with no apparent impairments
www.nature.com/articles/s41...
Reposted by Ahmet O. Ceceli
Distributed activity in the human posterior putamen distinguishes goal-directed from habitual control in humans https://www.biorxiv.org/content/10.1101/2025.11.26.690863v1
November 28, 2025 at 1:15 PM
Distributed activity in the human posterior putamen distinguishes goal-directed from habitual control in humans https://www.biorxiv.org/content/10.1101/2025.11.26.690863v1
Reposted by Ahmet O. Ceceli
New lab paper: "Emotional learning selectively distorts the temporal organization of memory: A quantitative synthesis." Across 17 different studies, fear conditioning consistently distorted temporal source memory for information encoded before and after. www.sciencedirect.com/science/arti...
Emotional learning selectively distorts the temporal organization of memory: A quantitative synthesis
Episodic memory allows us to remember when an event occurred by situating it within a coherent temporal context. Pavlovian fear conditioning, a widely…
www.sciencedirect.com
December 1, 2025 at 4:05 PM
New lab paper: "Emotional learning selectively distorts the temporal organization of memory: A quantitative synthesis." Across 17 different studies, fear conditioning consistently distorted temporal source memory for information encoded before and after. www.sciencedirect.com/science/arti...
Reposted by Ahmet O. Ceceli
1/2
New open access paper in which we apply the Nyquist-Shannon thereom from signal processing to 2 EMA datasets to figure out the optimal sampling frequency for EMA assessments.
🧪 #psychscisky #statssky
www.cambridge.org/core/journal...
New open access paper in which we apply the Nyquist-Shannon thereom from signal processing to 2 EMA datasets to figure out the optimal sampling frequency for EMA assessments.
🧪 #psychscisky #statssky
www.cambridge.org/core/journal...
Optimizing the frequency of ecological momentary assessments using signal processing | Psychological Medicine | Cambridge Core
Optimizing the frequency of ecological momentary assessments using signal processing - Volume 55
www.cambridge.org
November 27, 2025 at 12:04 AM
1/2
New open access paper in which we apply the Nyquist-Shannon thereom from signal processing to 2 EMA datasets to figure out the optimal sampling frequency for EMA assessments.
🧪 #psychscisky #statssky
www.cambridge.org/core/journal...
New open access paper in which we apply the Nyquist-Shannon thereom from signal processing to 2 EMA datasets to figure out the optimal sampling frequency for EMA assessments.
🧪 #psychscisky #statssky
www.cambridge.org/core/journal...
Very interesting paper framing decision biases as habit-like choice repetitions. I wonder if any element of non reinforced preference change (www.sciencedirect.com/science/arti...) is at work here.
Very happy that this is out www.nature.com/articles/s44.... Together with @stefankiebel.bsky.social we show that decision biases in context-dependent decision making, previously attributed to different forms of value normalization, are very well explained by habit-like action repetition.
Action repetition biases choice in context-dependent decision-making - Communications Psychology
This study shows that decision biases previously attributed to value normalization (e.g. relative value learning or range normalization) are better explained by action repetition. Repeating an action ...
www.nature.com
November 30, 2025 at 4:27 PM
Very interesting paper framing decision biases as habit-like choice repetitions. I wonder if any element of non reinforced preference change (www.sciencedirect.com/science/arti...) is at work here.
Big thanks to @pnas.org Kudos for highlighting our work showing PFC recovery with methylphenidate + memory modulation in cocaine addiction
www.growkudos.com/publications...
www.growkudos.com/publications...
Methylphenidate and drug memory modulation normalizes brain function in drug addiction
Individuals with cocaine use disorder underwent a brain imaging task designed to weaken drug memories by extinguishing reactivity to images that were previously associated with drug use. When methylph...
www.growkudos.com
November 21, 2025 at 4:08 AM
Big thanks to @pnas.org Kudos for highlighting our work showing PFC recovery with methylphenidate + memory modulation in cocaine addiction
www.growkudos.com/publications...
www.growkudos.com/publications...
Reposted by Ahmet O. Ceceli
We have at least TWO postdoctoral fellowship openings on our @unm.edu @casaa.bsky.social T32 NIAAA Training Grant, best consideration date for applications is Nov 15 2025. Join our phenomenal community and enjoy incredible quality of life in beautiful New Mexico. casaa.unm.edu/training/ins...
Application Process ::
Center on Alcohol, Substance use, And Addictions (CASAA) | The University of New Mexico
casaa.unm.edu
November 5, 2025 at 10:30 PM
We have at least TWO postdoctoral fellowship openings on our @unm.edu @casaa.bsky.social T32 NIAAA Training Grant, best consideration date for applications is Nov 15 2025. Join our phenomenal community and enjoy incredible quality of life in beautiful New Mexico. casaa.unm.edu/training/ins...
Excited to share our new paper in @pnas.org!!
Combining methylphenidate with memory updating (retrieval–extinction) normalized ventromedial prefrontal cortex function in people with cocaine addiction.
www.pnas.org/doi/abs/10.1...
Combining methylphenidate with memory updating (retrieval–extinction) normalized ventromedial prefrontal cortex function in people with cocaine addiction.
www.pnas.org/doi/abs/10.1...
The synergy of methylphenidate- and reconsolidation-based extinction normalizes ventromedial prefrontal function in drug addiction | PNAS
Drug-related memories can hinder abstinence goals in drug addiction. Promoting nondrugmemories
via ventromedial prefrontal cortex (vmPFC)- and amyg...
www.pnas.org
November 4, 2025 at 10:20 PM
Excited to share our new paper in @pnas.org!!
Combining methylphenidate with memory updating (retrieval–extinction) normalized ventromedial prefrontal cortex function in people with cocaine addiction.
www.pnas.org/doi/abs/10.1...
Combining methylphenidate with memory updating (retrieval–extinction) normalized ventromedial prefrontal cortex function in people with cocaine addiction.
www.pnas.org/doi/abs/10.1...
Reposted by Ahmet O. Ceceli
Excited to share this review in @biologicalpsych.bsky.social on using transfer learning to leverage large MRI datasets & enhance precision psychiatry!!
www.biologicalpsychiatryjournal.com/article/S000...
Fun collab with rockstars @diawang.bsky.social @bttyeo.bsky.social @avramholmes.bsky.social
www.biologicalpsychiatryjournal.com/article/S000...
Fun collab with rockstars @diawang.bsky.social @bttyeo.bsky.social @avramholmes.bsky.social
From big to small: Emerging methods for enhancing precision psychiatry through transfer learning
Identifying reliable links between individual differences in neurobiological features
and differences in symptom profiles or treatment outcomes is a primary goal of precision
psychiatry. Within this c...
www.biologicalpsychiatryjournal.com
October 30, 2025 at 3:21 PM
Excited to share this review in @biologicalpsych.bsky.social on using transfer learning to leverage large MRI datasets & enhance precision psychiatry!!
www.biologicalpsychiatryjournal.com/article/S000...
Fun collab with rockstars @diawang.bsky.social @bttyeo.bsky.social @avramholmes.bsky.social
www.biologicalpsychiatryjournal.com/article/S000...
Fun collab with rockstars @diawang.bsky.social @bttyeo.bsky.social @avramholmes.bsky.social
Reposted by Ahmet O. Ceceli
Our new paper is out! It offers a tool to assess collinearity impact on contrast estimates
*and*
uses simulations + MID data to show how common collinearity avoidance strategies can bias results.
Huge thanks to @russpoldrack.org , M Demidenko, and the ABCD folks.
🔗 direct.mit.edu/imag/article...
*and*
uses simulations + MID data to show how common collinearity avoidance strategies can bias results.
Huge thanks to @russpoldrack.org , M Demidenko, and the ABCD folks.
🔗 direct.mit.edu/imag/article...
Unintended bias in the pursuit of collinearity solutions in fMRI analysis
Abstract. In task functional magnetic resonance imaging (fMRI), collinearity between task regressors in time series models may impact power. When collinearity is identified after data collection, rese...
direct.mit.edu
October 29, 2025 at 7:13 PM
Our new paper is out! It offers a tool to assess collinearity impact on contrast estimates
*and*
uses simulations + MID data to show how common collinearity avoidance strategies can bias results.
Huge thanks to @russpoldrack.org , M Demidenko, and the ABCD folks.
🔗 direct.mit.edu/imag/article...
*and*
uses simulations + MID data to show how common collinearity avoidance strategies can bias results.
Huge thanks to @russpoldrack.org , M Demidenko, and the ABCD folks.
🔗 direct.mit.edu/imag/article...
Reposted by Ahmet O. Ceceli
New paper out in cognition with @arikahn.bsky.social, @nathanieldaw.bsky.social, Cate Hartley, and @katenuss.bsky.social !!
We show that children 👶 use predictive representations (e.g. SR) to guide their choices, providing an account of how they can make flexible choices in a changing world
We show that children 👶 use predictive representations (e.g. SR) to guide their choices, providing an account of how they can make flexible choices in a changing world
Children leverage predictive representations for flexible, value-guided choice
By harnessing a mental model of how the world works, learners can make flexible choices in changing environments. However, while children and adolesce…
www.sciencedirect.com
October 15, 2025 at 10:52 AM
New paper out in cognition with @arikahn.bsky.social, @nathanieldaw.bsky.social, Cate Hartley, and @katenuss.bsky.social !!
We show that children 👶 use predictive representations (e.g. SR) to guide their choices, providing an account of how they can make flexible choices in a changing world
We show that children 👶 use predictive representations (e.g. SR) to guide their choices, providing an account of how they can make flexible choices in a changing world
Reposted by Ahmet O. Ceceli
Really interesting work by Bakhurin and colleagues challenging the reward prediction error hypothesis of dopamine:
www.nature.com/articles/s41...
I love this figure which both echoes and undermines the famous figure from Schultz et al. (1997).
www.nature.com/articles/s41...
I love this figure which both echoes and undermines the famous figure from Schultz et al. (1997).
October 14, 2025 at 11:05 AM
Really interesting work by Bakhurin and colleagues challenging the reward prediction error hypothesis of dopamine:
www.nature.com/articles/s41...
I love this figure which both echoes and undermines the famous figure from Schultz et al. (1997).
www.nature.com/articles/s41...
I love this figure which both echoes and undermines the famous figure from Schultz et al. (1997).
Reposted by Ahmet O. Ceceli
Motivations are like emotions about (what we know about) possible outcomes. Sometimes incentives spur urgency to act, other times to comprehend. Neuromodulatory systems reflect these motivational moods and shape memories. Out now w @jiahou-poh.bsky.social!
www.annualreviews.org/content/jour...
www.annualreviews.org/content/jour...
Motivation as Neural Context for Adaptive Learning and Memory Formation
Our memories shape our perception of the world and guide adaptive behavior. Rather than a veridical record of experiences, memory is selective. An accumulating body of work suggests that motivational ...
www.annualreviews.org
October 13, 2025 at 4:39 AM
Motivations are like emotions about (what we know about) possible outcomes. Sometimes incentives spur urgency to act, other times to comprehend. Neuromodulatory systems reflect these motivational moods and shape memories. Out now w @jiahou-poh.bsky.social!
www.annualreviews.org/content/jour...
www.annualreviews.org/content/jour...
Reposted by Ahmet O. Ceceli
Excited to share recent collaborative work led by Hayley Thorpe published in Molecular Psychiatry: Genome-wide association studies of lifetime and frequency of cannabis use in 131,895 individuals www.nature.com/articles/s41...
Genome-wide association studies of lifetime and frequency of cannabis use in 131,895 individuals - Molecular Psychiatry
Molecular Psychiatry - Genome-wide association studies of lifetime and frequency of cannabis use in 131,895 individuals
www.nature.com
October 13, 2025 at 12:41 PM
Excited to share recent collaborative work led by Hayley Thorpe published in Molecular Psychiatry: Genome-wide association studies of lifetime and frequency of cannabis use in 131,895 individuals www.nature.com/articles/s41...
Reposted by Ahmet O. Ceceli
Using neuroimaging, @mountsinainyc.bsky.social's Dr. Rita Z. Goldstein, et al. simultaneously examine sex differences & hormonal effects on brain responses to drug cues, and their down-regulation thru cognitive reappraisal, in subjects w/ #SubstanceUseDisorders👉
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
October 8, 2025 at 12:57 PM
Using neuroimaging, @mountsinainyc.bsky.social's Dr. Rita Z. Goldstein, et al. simultaneously examine sex differences & hormonal effects on brain responses to drug cues, and their down-regulation thru cognitive reappraisal, in subjects w/ #SubstanceUseDisorders👉
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Ahmet O. Ceceli
Reposted by Ahmet O. Ceceli
Excited to finally share this collaborative effort led by Philip Boone, Michael Talkowski and @abepalmer.bsky.social!
Aberrant recursive splicing in a human disease locus https://www.biorxiv.org/content/10.1101/2025.08.14.666599v1
August 15, 2025 at 3:23 PM
Excited to finally share this collaborative effort led by Philip Boone, Michael Talkowski and @abepalmer.bsky.social!
Reposted by Ahmet O. Ceceli
I will be interviewing for a clinical psychology PhD student in the Precision Psychopathology + Dynamic Immunopsychiatry Lab this interview cycle.
Please see our website for more info about what we do + share with applicants you think might be a good fit.
share.google/uJRyS3NY9Kdo...
Please see our website for more info about what we do + share with applicants you think might be a good fit.
share.google/uJRyS3NY9Kdo...
Precision Psychopathology + Dynamic Immunopsychiatry Lab – University of Pennsylvania, Department of Psychology
share.google
August 7, 2025 at 11:23 AM
I will be interviewing for a clinical psychology PhD student in the Precision Psychopathology + Dynamic Immunopsychiatry Lab this interview cycle.
Please see our website for more info about what we do + share with applicants you think might be a good fit.
share.google/uJRyS3NY9Kdo...
Please see our website for more info about what we do + share with applicants you think might be a good fit.
share.google/uJRyS3NY9Kdo...
Overwhelmed (in the best way!), speechless, and many other adjectives..Thank you, @bbrfoundation.bsky.social for propelling my research in addiction neuroscience with the 2025 Young Investigator Award + thanks as always to @narcatms.bsky.social and Mount Sinai for the unwavering support!
August 6, 2025 at 2:49 PM
Overwhelmed (in the best way!), speechless, and many other adjectives..Thank you, @bbrfoundation.bsky.social for propelling my research in addiction neuroscience with the 2025 Young Investigator Award + thanks as always to @narcatms.bsky.social and Mount Sinai for the unwavering support!
Reposted by Ahmet O. Ceceli
Neat registered report from @mattmattoni.bsky.social @dvsmith.bsky.social @mindimager.bsky.social and @olinotom.bsky.social diving into the tension between nomothetic (group-level) v. idiographic (individual specific) in functional connectivity models.
#Neuroskyence
direct.mit.edu/imag/article...
#Neuroskyence
direct.mit.edu/imag/article...
Functional Connectivity Heterogeneity and Consequences for Clinical and Cognitive Prediction
AbstractFunctional connectivity is frequently used to assess dynamic brain functioning and predict individual differences in behavioral outcomes, such as psychopathology. Inferences from functional co...
direct.mit.edu
July 27, 2025 at 9:36 PM
Neat registered report from @mattmattoni.bsky.social @dvsmith.bsky.social @mindimager.bsky.social and @olinotom.bsky.social diving into the tension between nomothetic (group-level) v. idiographic (individual specific) in functional connectivity models.
#Neuroskyence
direct.mit.edu/imag/article...
#Neuroskyence
direct.mit.edu/imag/article...
Reposted by Ahmet O. Ceceli
I’m looking for a postdoc to join me at UCSD, ideally a clinical psychologist PhD who can deliver mindfulness interventions as well as write papers and do analyses. I have one of the world’s largest psychophysiology datasets of opioid misuse, OUD, & chronic pain. Competitive salary. DM or email.
July 27, 2025 at 8:15 PM
I’m looking for a postdoc to join me at UCSD, ideally a clinical psychologist PhD who can deliver mindfulness interventions as well as write papers and do analyses. I have one of the world’s largest psychophysiology datasets of opioid misuse, OUD, & chronic pain. Competitive salary. DM or email.
Reposted by Ahmet O. Ceceli
This will change everything!
Finally, neuroscientists have discovered a pill to treat their craving for simple brain explanations. It's very effective, provided it's taken daily, but no one knows how or why.
link.springer.com/article/10.1...
Finally, neuroscientists have discovered a pill to treat their craving for simple brain explanations. It's very effective, provided it's taken daily, but no one knows how or why.
link.springer.com/article/10.1...
July 27, 2025 at 10:38 AM
This will change everything!
Finally, neuroscientists have discovered a pill to treat their craving for simple brain explanations. It's very effective, provided it's taken daily, but no one knows how or why.
link.springer.com/article/10.1...
Finally, neuroscientists have discovered a pill to treat their craving for simple brain explanations. It's very effective, provided it's taken daily, but no one knows how or why.
link.springer.com/article/10.1...
Reposted by Ahmet O. Ceceli
Ok, reinforcement learning fans: RL is great, but what do we do when there's no obvious reward from the environment? What about perfecting a golf swing or a foxtrot or a musical performance? We may have an answer. A tale of 🐦 🎶 + 🧠. 🧵1/ #bioacoustics #prattle 💬 #neuroai #compneuro
I am happy to share our new preprint! In this work, we proposed a theory about how zebra finches bootstrap their error signals for self-guided RL via predictive coding 👇 www.biorxiv.org/content/10.1...
Correctness is its own reward: bootstrapping error signals in self-guided reinforcement learning
Reinforcement learning (RL) offers a compelling account of how agents learn complex behaviors by trial and error, yet RL is predicated on the existence of a reward function provided by the agent's env...
www.biorxiv.org
July 24, 2025 at 2:29 PM
Ok, reinforcement learning fans: RL is great, but what do we do when there's no obvious reward from the environment? What about perfecting a golf swing or a foxtrot or a musical performance? We may have an answer. A tale of 🐦 🎶 + 🧠. 🧵1/ #bioacoustics #prattle 💬 #neuroai #compneuro