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Reposted by Ahmet O. Ceceli

Sam Gershman @gershbrain.bsky.social · 22h

Really interesting work by Bakhurin and colleagues challenging the reward prediction error hypothesis of dopamine:
www.nature.com/articles/s41...
I love this figure which both echoes and undermines the famous figure from Schultz et al. (1997).

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Reposted by Ahmet O. Ceceli

Alison Adcock @ralisonadcock.bsky.social · 2d

Motivations are like emotions about (what we know about) possible outcomes. Sometimes incentives spur urgency to act, other times to comprehend. Neuromodulatory systems reflect these motivational moods and shape memories. Out now w @jiahou-poh.bsky.social!
www.annualreviews.org/content/jour...

Motivation as Neural Context for Adaptive Learning and Memory Formation

Our memories shape our perception of the world and guide adaptive behavior. Rather than a veridical record of experiences, memory is selective. An accumulating body of work suggests that motivational ...

www.annualreviews.org

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Reposted by Ahmet O. Ceceli

Jibran Khokhar @drjkhokhar.bsky.social · 1d

Excited to share recent collaborative work led by Hayley Thorpe published in Molecular Psychiatry: Genome-wide association studies of lifetime and frequency of cannabis use in 131,895 individuals www.nature.com/articles/s41...

Genome-wide association studies of lifetime and frequency of cannabis use in 131,895 individuals - Molecular Psychiatry

Molecular Psychiatry - Genome-wide association studies of lifetime and frequency of cannabis use in 131,895 individuals

www.nature.com

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Ahmet O. Ceceli @aoceceli.bsky.social · 4d

Inspirational, congrats!

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Reposted by Ahmet O. Ceceli

The Friedman Brain Institute @sinaibrain.bsky.social · 6d

Using neuroimaging, @mountsinainyc.bsky.social's Dr. Rita Z. Goldstein, et al. simultaneously examine sex differences & hormonal effects on brain responses to drug cues, and their down-regulation thru cognitive reappraisal, in subjects w/ #SubstanceUseDisorders👉
www.sciencedirect.com/science/arti...

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Reposted by Ahmet O. Ceceli

Alex Shackman @ajshackman.bsky.social · Sep 9

www.nature.com/articles/s41...

Impulsivity and neuroticism share distinct functional connectivity signatures with alcohol-use risk in youth - Molecular Psychiatry

Molecular Psychiatry - Impulsivity and neuroticism share distinct functional connectivity signatures with alcohol-use risk in youth

www.nature.com

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Ahmet O. Ceceli @aoceceli.bsky.social · Aug 18

academic.oup.com/brain/articl...

Shared orbitofrontal dynamics to a drug-themed movie track craving and recovery in heroin addiction

Kronberg et al. measured fMRI responses to a drug-themed movie in individuals with heroin use disorder. Responses in the orbitofrontal cortex were biased t

academic.oup.com

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Ahmet O. Ceceli @aoceceli.bsky.social · Aug 18

Shameless self plug :) we (@gregkronberg.bsky.social, @narcatms.bsky.social et al) recently showed: when inpatients with heroin use disorder watch Trainspotting during fmri, the OFC is synchronized to drug scenes, which decreases after ~15 weeks of treatment as a function of a reduction in craving

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Reposted by Ahmet O. Ceceli

Jibran Khokhar @drjkhokhar.bsky.social · Aug 15

Excited to finally share this collaborative effort led by Philip Boone, Michael Talkowski and @abepalmer.bsky.social!

bioRxivpreprint @biorxivpreprint.bsky.social · Aug 15

Aberrant recursive splicing in a human disease locus https://www.biorxiv.org/content/10.1101/2025.08.14.666599v1

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Reposted by Ahmet O. Ceceli

Daniel P. Moriarity @dpmoriarity.bsky.social · Aug 7

I will be interviewing for a clinical psychology PhD student in the Precision Psychopathology + Dynamic Immunopsychiatry Lab this interview cycle.

Please see our website for more info about what we do + share with applicants you think might be a good fit.

share.google/uJRyS3NY9Kdo...

Precision Psychopathology + Dynamic Immunopsychiatry Lab – University of Pennsylvania, Department of Psychology

share.google

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Ahmet O. Ceceli @aoceceli.bsky.social · Aug 6

Overwhelmed (in the best way!), speechless, and many other adjectives..Thank you, @bbrfoundation.bsky.social for propelling my research in addiction neuroscience with the 2025 Young Investigator Award + thanks as always to @narcatms.bsky.social and Mount Sinai for the unwavering support!

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Reposted by Ahmet O. Ceceli

Daniel P. Moriarity @dpmoriarity.bsky.social · Jul 27

Neat registered report from @mattmattoni.bsky.social @dvsmith.bsky.social @mindimager.bsky.social and @olinotom.bsky.social diving into the tension between nomothetic (group-level) v. idiographic (individual specific) in functional connectivity models.

#Neuroskyence

direct.mit.edu/imag/article...

Functional Connectivity Heterogeneity and Consequences for Clinical and Cognitive Prediction

AbstractFunctional connectivity is frequently used to assess dynamic brain functioning and predict individual differences in behavioral outcomes, such as psychopathology. Inferences from functional co...

direct.mit.edu

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Reposted by Ahmet O. Ceceli

Eric L. Garland @drericgarland.bsky.social · Jul 27

I’m looking for a postdoc to join me at UCSD, ideally a clinical psychologist PhD who can deliver mindfulness interventions as well as write papers and do analyses. I have one of the world’s largest psychophysiology datasets of opioid misuse, OUD, & chronic pain. Competitive salary. DM or email.

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Reposted by Ahmet O. Ceceli

Serge Ahmed @sergeahmed.bsky.social · Jul 27

This will change everything!

Finally, neuroscientists have discovered a pill to treat their craving for simple brain explanations. It's very effective, provided it's taken daily, but no one knows how or why.

link.springer.com/article/10.1...

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Reposted by Ahmet O. Ceceli

John Pearson @jmxpearson.bsky.social · Jul 24

Ok, reinforcement learning fans: RL is great, but what do we do when there's no obvious reward from the environment? What about perfecting a golf swing or a foxtrot or a musical performance? We may have an answer. A tale of 🐦 🎶 + 🧠. 🧵1/ #bioacoustics #prattle 💬 #neuroai #compneuro

Ziyi Gong @gongziyida.bsky.social · Jul 24

I am happy to share our new preprint! In this work, we proposed a theory about how zebra finches bootstrap their error signals for self-guided RL via predictive coding 👇 www.biorxiv.org/content/10.1...

Correctness is its own reward: bootstrapping error signals in self-guided reinforcement learning

Reinforcement learning (RL) offers a compelling account of how agents learn complex behaviors by trial and error, yet RL is predicated on the existence of a reward function provided by the agent's env...

www.biorxiv.org

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Reposted by Ahmet O. Ceceli

Proceedings of the National Academy of Sciences @pnas.org · Jul 25

In an MRI study with 45 participants using deep-learning models, hippocampal activity was predictive of experiential choices, such as choosing a song to listen to. For choices involving risk, the ventral striatum and insula were active. In PNAS: www.pnas.org/doi/10.1073/...

A person chooses songs at a jukebox. Stock photo.

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Reposted by Ahmet O. Ceceli

tor @torwager.bsky.social · Jul 23

Online #fMRI course coming up August 6-8!
3-day intensive with lectures and hands-on analysis for all skill levels. #SPM, #ICA, #DataScience with @vcalhoun.bsky.social and Kent Kiehl. We love teaching this course and meeting students from all areas! Info+Reg here:
sites.google.com/dartmouth.ed...

fMRI Course

Instructors

sites.google.com

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Ahmet O. Ceceli @aoceceli.bsky.social · Jul 22

Major props to the team: Yuefeng Huang, @gregkronberg.bsky.social, @nataliemcclain.bsky.social, Sarah King, Eduardo Butelman, Nelly Alia-Klein, Rita Goldstein: @narcatms.bsky.social for their brilliant contributions

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Ahmet O. Ceceli @aoceceli.bsky.social · Jul 22

Catch this in @annualreviews.bsky.social of Psychology in the January 2026 issue!

Ahmet O. Ceceli @aoceceli.bsky.social · Jul 22

A colossal effort from the NARC lab: we reviewed the recent advances in drug addiction research from the lens of the impaired response inhibition and salience attribution model. A one stop shop for theory, severity, recovery, and novel directions.
osf.io/preprints/ps...

OSF

osf.io

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Ahmet O. Ceceli @aoceceli.bsky.social · Jul 19

Super excited to contribute to this book with our chapter "Enhancing Ecological Validity in Habit Research via Naturalistic Methods" (with Elizabeth Tricomi). Thanks, @dvsmith.bsky.social, @thepsychologist.bsky.social, and @dfareri.bsky.social for organizing!

osf.io/preprints/ps...

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Reposted by Ahmet O. Ceceli

Jamie Hanson @jamielarsh.bsky.social · Jul 18

Changes in Model-Based and Model-Free Control Prospectively Predict Drinking Trajectories in Young Men www.biologicalpsychiatryjournal.com/article/S000...

Changes in Model-Based and Model-Free Control Prospectively Predict Drinking Trajectories in Young Men

Expanding our previous findings that model-based/model-free (MB/MF) control—often conceptualized as goal-directed and habitual behavior—at age 18 is associated with alcohol drinking trajectories over ...

www.biologicalpsychiatryjournal.com

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Reposted by Ahmet O. Ceceli

Jamie Hanson @jamielarsh.bsky.social · Jul 18

Challenging the status quo: A guide to open and reproducible neuroimaging for early career researchers direct.mit.edu/imag/article...

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Reposted by Ahmet O. Ceceli

Thomas Yeo @bttyeo.bsky.social · Jul 17

9/ Check out the actual study for many more analyses, e.g., phenotypic variation, scan parameters, signal to noise ratio, etc! doi.org/10.1038/s415...

Thank you to the editor @meharpist.bsky.social and anonymous reviewers for the many helpful suggestions, which greatly improved the study.

Longer scans boost prediction and cut costs in brain-wide association studies - Nature

Although the number of participants is important for phenotypic prediction accuracy in brain-wide association studies using functional MRI, scanning for at least 30 min offers the greatest cost effect...

doi.org

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Reposted by Ahmet O. Ceceli

Alex Shackman @ajshackman.bsky.social · Jul 18

lsmagazine.wisc.edu/issues/sprin...

Researching AI to Help With Addiction Recovery

John Curtin’s lab is using artificial intelligence to help people who struggle with alcohol or substance abuse avoid relapses.

lsmagazine.wisc.edu

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