Andy Willis
@andyw123.bsky.social
Senior post-doc researcher | trials methodology, public health, health inequalities | University College Cork
Reposted by Andy Willis
Key concepts series: Estimands: what they are and why we should use them - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Estimands: what they are and why we should use them
In clinical trials, post-randomisation events, such as treatment discontinuation or
the use of rescue medication, can complicate the interpretation of results. An estimand
is a precise description of ...
www.jclinepi.com
November 17, 2025 at 7:20 PM
Key concepts series: Estimands: what they are and why we should use them - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Reposted by Andy Willis
What drives willingness to participate in health research?
Led by our #PhD student Zara Kayani, participation and consent to data linkage varies across demographic groups.
Inclusive recruitment strategies are essential to engage underserved communities.
journals.plos.org/plosone/arti...
Led by our #PhD student Zara Kayani, participation and consent to data linkage varies across demographic groups.
Inclusive recruitment strategies are essential to engage underserved communities.
journals.plos.org/plosone/arti...
Which demographic characteristics are associated with willingness to take part in recontact studies? A cross-sectional study
Background Lower rates of participation in research by ethnic minority groups and socioeconomically deprived populations has led to efforts to develop recruitment strategies which aim to address this ...
journals.plos.org
November 5, 2025 at 9:32 AM
What drives willingness to participate in health research?
Led by our #PhD student Zara Kayani, participation and consent to data linkage varies across demographic groups.
Inclusive recruitment strategies are essential to engage underserved communities.
journals.plos.org/plosone/arti...
Led by our #PhD student Zara Kayani, participation and consent to data linkage varies across demographic groups.
Inclusive recruitment strategies are essential to engage underserved communities.
journals.plos.org/plosone/arti...
Reposted by Andy Willis
Retrospective use of the PRECIS-2 trial design tool to assess design choices in randomised controlled trials; An empirical review - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Retrospective use of the PRECIS-2 trial design tool to assess design choices in randomised controlled trials; An empirical review
The Pragmatic-Explanatory Continuum Indicator Summary (PRECIS-2) tool has been widely
used to help investigators design randomised trials, facilitating the task of aligning
design choices with an expl...
www.jclinepi.com
September 18, 2025 at 7:28 PM
Retrospective use of the PRECIS-2 trial design tool to assess design choices in randomised controlled trials; An empirical review - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Reposted by Andy Willis
📣 Our @streweek.bsky.social is lead author on an editorial in #Trials outlining a new mandate in the journal - mandating the reporting of six key participant characteristics in any protocol/trial report submitted to Trials on or after 1st Jan 2026. 1/2
trialsjournal.biomedcentral.com/articles/10....
trialsjournal.biomedcentral.com/articles/10....
September 15, 2025 at 11:24 AM
📣 Our @streweek.bsky.social is lead author on an editorial in #Trials outlining a new mandate in the journal - mandating the reporting of six key participant characteristics in any protocol/trial report submitted to Trials on or after 1st Jan 2026. 1/2
trialsjournal.biomedcentral.com/articles/10....
trialsjournal.biomedcentral.com/articles/10....
Reposted by Andy Willis
Fantastic to see Prof Frances Shiely, our Director of Education, highlighting the great work of the SENSITISE @sensitise-eu.bsky.social project on Newstalk with Pat Kenny.
Take a listen: www.newstalk.com/podcasts/hig...
Take a listen: www.newstalk.com/podcasts/hig...
UCC aims to make health research more inclusive | Newstalk
A new campaign at UCC aims to make health research more inclusive, to include under-served groups...
www.newstalk.com
September 10, 2025 at 10:44 AM
Fantastic to see Prof Frances Shiely, our Director of Education, highlighting the great work of the SENSITISE @sensitise-eu.bsky.social project on Newstalk with Pat Kenny.
Take a listen: www.newstalk.com/podcasts/hig...
Take a listen: www.newstalk.com/podcasts/hig...
Reposted by Andy Willis
📢 Our new review on #LongCovid: 50 studies, 14M+ people. COVID linked to ↑ risk in 39/40 symptoms.
Top risks (likelihood compared to controls):
👃 Smell loss (4.3x)
👅 Taste loss (3.7x)
🧠 Brain fog (2.7x)
💇 Hair loss (2.4x)
🏥 Hospitalised = higher risk
🔗 doi.org/10.1038/s414...
@arc-em.bsky.social
Top risks (likelihood compared to controls):
👃 Smell loss (4.3x)
👅 Taste loss (3.7x)
🧠 Brain fog (2.7x)
💇 Hair loss (2.4x)
🏥 Hospitalised = higher risk
🔗 doi.org/10.1038/s414...
@arc-em.bsky.social
The risk of Long Covid symptoms: a systematic review and meta-analysis of controlled studies - Nature Communications
Estimating the risk of long COVID is challenging because many of its symptoms are associated with other conditions. Here, the authors conduct a systematic review and meta-analysis of studies that esti...
doi.org
May 8, 2025 at 7:59 AM
📢 Our new review on #LongCovid: 50 studies, 14M+ people. COVID linked to ↑ risk in 39/40 symptoms.
Top risks (likelihood compared to controls):
👃 Smell loss (4.3x)
👅 Taste loss (3.7x)
🧠 Brain fog (2.7x)
💇 Hair loss (2.4x)
🏥 Hospitalised = higher risk
🔗 doi.org/10.1038/s414...
@arc-em.bsky.social
Top risks (likelihood compared to controls):
👃 Smell loss (4.3x)
👅 Taste loss (3.7x)
🧠 Brain fog (2.7x)
💇 Hair loss (2.4x)
🏥 Hospitalised = higher risk
🔗 doi.org/10.1038/s414...
@arc-em.bsky.social
Reposted by Andy Willis
Use of the pragmatic-explanatory continuum indicator summary tool in low- and middle-income country settings: Systematic review - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Use of the pragmatic-explanatory continuum indicator summary tool in low- and middle-income country settings: Systematic review
The pragmatic-explanatory continuum indicator summary (PRECIS) tools were created
to help researchers design better studies. The tools were developed mainly by researchers
from developed Western natio...
www.jclinepi.com
May 5, 2025 at 8:29 PM
Use of the pragmatic-explanatory continuum indicator summary tool in low- and middle-income country settings: Systematic review - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Reposted by Andy Willis
To kick off #MethodologyMonday in May, we bring you a poignant article by the Editors in Chief of the Journal of Clinical Epidemiology. They address the “elephant in the room”, the upheaval of the global evidence research eco-systems pursued by the US administration.
www.jclinepi.com/article/S089...
www.jclinepi.com/article/S089...
May 5, 2025 at 1:20 PM
To kick off #MethodologyMonday in May, we bring you a poignant article by the Editors in Chief of the Journal of Clinical Epidemiology. They address the “elephant in the room”, the upheaval of the global evidence research eco-systems pursued by the US administration.
www.jclinepi.com/article/S089...
www.jclinepi.com/article/S089...
Reposted by Andy Willis
Our PhD student is interested in hearing from less heard voices on their views on health research and how we can be more inclusive. Please do share and if you can help do get in touch with Zara via the details below.
CC co-supervisor @andyw123.bsky.social
CC co-supervisor @andyw123.bsky.social
📢 Help shape health research!
Are you aged 18-80 and from a South Asian or African/Caribbean background with long-term health conditions? We want to hear from you!
Share your experiences and join our PhD research.
📧 Contact: [email protected]
@ashrouten.com @ethnichealthres.bsky.social
Are you aged 18-80 and from a South Asian or African/Caribbean background with long-term health conditions? We want to hear from you!
Share your experiences and join our PhD research.
📧 Contact: [email protected]
@ashrouten.com @ethnichealthres.bsky.social
March 27, 2025 at 9:38 AM
Our PhD student is interested in hearing from less heard voices on their views on health research and how we can be more inclusive. Please do share and if you can help do get in touch with Zara via the details below.
CC co-supervisor @andyw123.bsky.social
CC co-supervisor @andyw123.bsky.social
Reposted by Andy Willis
🇪🇺 Clinical trials are the gold standard for demonstrating the benefits of medical innovation, including anti-cancer treatments, but many EU patients face barriers to access.
👇Read the article on equitable access to cancer #clinicaltrials in #Eurohealth: tinyurl.com/EHcancerdial...
#CancerResearch
👇Read the article on equitable access to cancer #clinicaltrials in #Eurohealth: tinyurl.com/EHcancerdial...
#CancerResearch
March 24, 2025 at 3:46 PM
🇪🇺 Clinical trials are the gold standard for demonstrating the benefits of medical innovation, including anti-cancer treatments, but many EU patients face barriers to access.
👇Read the article on equitable access to cancer #clinicaltrials in #Eurohealth: tinyurl.com/EHcancerdial...
#CancerResearch
👇Read the article on equitable access to cancer #clinicaltrials in #Eurohealth: tinyurl.com/EHcancerdial...
#CancerResearch
Reposted by Andy Willis
KLAXON 🚨: Indie SAGE has come out of retirement to release a new short report standing up for diversity, equity and inclusion (DEI) in the sciences!
DEI is not just the right thing to do, it *improves* the quality of the science. Please read and share.
independentsage.org/wp-content/u...
1/2
DEI is not just the right thing to do, it *improves* the quality of the science. Please read and share.
independentsage.org/wp-content/u...
1/2
March 17, 2025 at 11:53 AM
KLAXON 🚨: Indie SAGE has come out of retirement to release a new short report standing up for diversity, equity and inclusion (DEI) in the sciences!
DEI is not just the right thing to do, it *improves* the quality of the science. Please read and share.
independentsage.org/wp-content/u...
1/2
DEI is not just the right thing to do, it *improves* the quality of the science. Please read and share.
independentsage.org/wp-content/u...
1/2
Reposted by Andy Willis
Measuring the environmental impact of health interventions in randomised controlled trials – a scoping review - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Measuring the environmental impact of health interventions in randomised controlled trials – a scoping review
Healthcare accounts for 4% of the overall greenhouse gas emissions worldwide. Reducing
carbon emissions is a key strategic aim for health systems in multiple countries.
To achieve this, environmental ...
www.jclinepi.com
March 9, 2025 at 8:26 PM
Measuring the environmental impact of health interventions in randomised controlled trials – a scoping review - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Reposted by Andy Willis
📣 The EU has launched a new map of #ClinicalTrials. Thanks to this new tool patients will be able to locate trials for potential enrolment in their area. Read more about this map 🗺️ www.ema.europa.eu/en/news/new-...
New clinical trial map launched in the EU | European Medicines Agency (EMA)
Patients can locate trials for potential enrolment in their area
www.ema.europa.eu
March 3, 2025 at 2:16 PM
📣 The EU has launched a new map of #ClinicalTrials. Thanks to this new tool patients will be able to locate trials for potential enrolment in their area. Read more about this map 🗺️ www.ema.europa.eu/en/news/new-...
Reposted by Andy Willis
www.heec.co.uk/resource/sev...
7 High impact interventions to address health inequalities- many interface with primary care with community and peer supported interventions necessary to close the health literacy and self-advocacy gap.
#PrimaryCare #GeneralPractice
7 High impact interventions to address health inequalities- many interface with primary care with community and peer supported interventions necessary to close the health literacy and self-advocacy gap.
#PrimaryCare #GeneralPractice
Seven high-impact interventions to tackle health and care inequalities - Health Equity Evidence Centre
We have undertaken a series of 10 evidence reviews for NHS England and here highlight seven interventions and programmes with the strongest evidence base.
www.heec.co.uk
December 22, 2024 at 4:23 PM
www.heec.co.uk/resource/sev...
7 High impact interventions to address health inequalities- many interface with primary care with community and peer supported interventions necessary to close the health literacy and self-advocacy gap.
#PrimaryCare #GeneralPractice
7 High impact interventions to address health inequalities- many interface with primary care with community and peer supported interventions necessary to close the health literacy and self-advocacy gap.
#PrimaryCare #GeneralPractice
Reposted by Andy Willis
Viewpoint discusses the challenges of implementing findings from pragmatic clinical trials in health care systems.
https://ja.ma/4gvoewT
https://ja.ma/4gvoewT
December 11, 2024 at 1:00 PM
Viewpoint discusses the challenges of implementing findings from pragmatic clinical trials in health care systems.
https://ja.ma/4gvoewT
https://ja.ma/4gvoewT
Thoughts and feedback from users of the PRECIS-2 trial design tool, and our thoughts on what might change for its next update. www.sciencedirect.com/science/arti...
Comments, suggestions, and criticisms of the Pragmatic Explanatory Continuum Indicator Summary-2 design tool: a citation analysis
The pragmatic explanatory continuum indicator summary (PRECIS) tool, initially published in 2009 and revised in 2015, was created to assist trialists …
www.sciencedirect.com
November 29, 2024 at 2:05 PM
Thoughts and feedback from users of the PRECIS-2 trial design tool, and our thoughts on what might change for its next update. www.sciencedirect.com/science/arti...
Reposted by Andy Willis
I'm pretty new to Bluesky and haven't found all the trials methods researchers yet! Trying to bring us all together in one place for others to find & fill my feed with all things trials. Please feel free to share and let me know if you'd like added. go.bsky.app/AsP6Yta
November 19, 2024 at 7:23 PM
I'm pretty new to Bluesky and haven't found all the trials methods researchers yet! Trying to bring us all together in one place for others to find & fill my feed with all things trials. Please feel free to share and let me know if you'd like added. go.bsky.app/AsP6Yta