Alberti Lab @ TU Dresden
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albertilab-tud.bsky.social
Alberti Lab @ TU Dresden
@albertilab-tud.bsky.social
Our group aims to elucidate the molecular basis of cytoplasmic organization.

stress granules I biomolecular condensates I phase separation

https://tu-dresden.de/cmcb/biotec/forschungsgruppen/alberti
++++ We are hiring ++++

The DFG-funded Research Training Group RTG 3120 – Biomolecular Condensates: From Physics to biological Functions” in Dresden is currently recruiting PhD-candidates.

More Info here: dresdencondensates.org/join-us/

Please apply until October 31,2025
September 23, 2025 at 7:43 AM
Reposted by Alberti Lab @ TU Dresden
Patrick's paper is finally out, a label-free method to measure the composition of multicomponent biomolecular condensates!
September 3, 2025 at 11:53 AM
Reposted by Alberti Lab @ TU Dresden
Congratulations to Kai Simons, one of our founding directors, for receiving the Cothenius-Medal of the German National Academy of Sciences Leopoldina @leopoldina.org for his insights into the function of cell membranes. 🎉 www.mpi-cbg.de/news-outreac...
Für sein herausragendes wissenschaftliches Lebenswerk wird Leopoldina-Mitglied Kai Simons, Direktor emeritus am Max-Planck-Institut für molekulare Zellbiologie und Genetik in Dresden @mpi-cbg.de, mit der Cothenius-Medaille geehrt. ➡️ www.leopoldina.org/presse-1/nac...
September 5, 2025 at 12:08 PM
Reposted by Alberti Lab @ TU Dresden
🔬 #BSc or #MSc and research? Come to @tudresden.bsky.social & the CMCB!

Meet our iGEM team, supervised by @albertilab-tud.bsky.social and the Honigmann lab, ready for the @igemhq.bsky.social competition.

Video with EN subtitles ➡️ youtu.be/MMffDJyjeGg

#StudyinGermany #LifeSciences
July 30, 2025 at 10:13 AM
Great trip to Prague with (part of) the team in perfect weather conditions.
June 25, 2025 at 12:47 PM
Reposted by Alberti Lab @ TU Dresden
Lively poster session after a day full of talks (😅) by @drummondlab.bsky.social, Allie Obermeyer, @albertilab-tud.bsky.social, Sam Safran, and @tanjamittag.bsky.social at the #KITP biomol25 conference on biomolecular condensates. Great conversations between theorists and experimentalists!
June 16, 2025 at 11:09 PM
Reposted by Alberti Lab @ TU Dresden
A team @mpi-cbg.de from @hymanlab.bsky.social & the @edinburghup.bsky.social (Richard Wheeler group) has identified the molecule lipoamide that can prevent the formation of pathological stress granules - protein-rich condensates associated with cellular stress and ALS. www.mpi-cbg.de/news-outreac...
Molecule Disarms Cellular Stress Granules Linked to ALS
Discovery by researchers in Dresden and Edinburgh points to new understanding of the onset of ALS.
www.mpi-cbg.de
May 27, 2025 at 2:14 PM
Reposted by Alberti Lab @ TU Dresden
Collaboration with the Alberti lab @albertilab-tud.bsky.social here in Dresden @biotec-tud.bsky.social and Jeetain Mittal group in Texas jeetain.wixsite.com/mittal-lab
@rnadavid.bsky.social @pombo-garcialab.bsky.social
Home | MyResearchWebsite
jeetain.wixsite.com
May 23, 2025 at 3:01 PM
Reposted by Alberti Lab @ TU Dresden
Outstanding success: 🎉 #TUDresden shines with 5 Clusters of Excellence. @dfg.de & @wissenschaftsrat.de announced that decision today. TUD has impressively proven its claim to be a top university for the 21st century.
ℹ️ tu-dresden.de/tu-dresden/n...
May 22, 2025 at 4:54 PM
Reposted by Alberti Lab @ TU Dresden
Trigger warning: FOMO

How often do you go to a conference where you are excited about EVERY SINGLE TALK! Well, I guess it helps if you get to make the program. 😀

"Biomolecular condensates: From fundamental principles to applications in health and biotech" kicking off at 9 AM!
May 13, 2025 at 5:31 AM
Reposted by Alberti Lab @ TU Dresden
Das Leben erkennen: 🔬 Wie lassen sich Begegnungen von Molekülen sichtbar machen & was bedeutet das für die Entwicklung neuer Medikamente? Prof. Ulrich Rant stellt sich & seinen Forschungsschwerpunkt am 15.5. in der Universitätsweiten Antrittsvorlesung vor.
ℹ️ tu-dresden.de/tu-dresden/n...
Sensing life's interactions: 🔬 Prof. Ulrich Rant develops biosensoring technologies that can make the invisible bonds & dissolutions between single molecules visible. This can deepen our understanding of how they act in complex biological environments like cancer cells.
🎥 youtu.be/Tht3IDQgn9k
May 14, 2025 at 8:04 AM
Reposted by Alberti Lab @ TU Dresden
This summer in beautiful Santa Barbara we will run a 3-day conference on “Biological Physics of Biomolecular Condensates: Bridging Theory and Experiment” June 16 to 18th. Register now: www.kitp.ucsb.edu/activities/b...
March 12, 2025 at 3:58 PM
Reposted by Alberti Lab @ TU Dresden
All atom simulations of peptides were used to investigate differences in pair interactions in dilute vs. dense phase mimics of condensates. Backbone-mediated interactions were found to weaken pairwise associations in dense phases giving rise to percolated networks. doi.org/10.1038/s420...
Backbone-mediated weakening of pairwise interactions enables percolation in peptide-based mimics of protein condensates - Communications Chemistry
Biomolecular condensates formed by intrinsically disordered protein condensates are known to be semidilute solutions, however, the molecular interactions in the dilute versus dense phases remain under...
doi.org
April 6, 2025 at 10:27 AM
Welcome to our new Master students Samyuktha, Louis and Georg!
We wish you great success with your projects!.
It's wonderful to have you in the lab!

photos by Magdalena Gonciarz
April 8, 2025 at 8:23 AM
Applications for our international and interdisciplinary Master's Programs are now open!

The applications start on April 1 and run until May 31, 2025.

For detailed information please visit our website
tu-dresden.de/cmcb/die-ein...
April 2, 2025 at 7:03 AM
Reposted by Alberti Lab @ TU Dresden
The @tothpetroczylab.bsky.social together with the @albertilab-tud.bsky.social developed SHARK-capture to detect recurring patterns (motifs) in intrinsically disordered protein regions (IDRs). Publication in Protein Science. www.mpi-cbg.de/news-outreac...
March 25, 2025 at 3:45 PM
Reposted by Alberti Lab @ TU Dresden
ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes!

Annexin A11 tethers RNP granules to membranes in a Ca2+ dependent manner.

@abelljonny.bsky.social, @michael-e-ward.bsky.social, et al.

www.nature.com/articles/s41...
ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes - Nature Communications
Nixon-Abell et al. show that ANXA11 condensation on lysosomal membranes causes a coupled phase transition of the underlying lipids and mechanical stiffening of the overall ensemble involved in RNP gra...
www.nature.com
March 23, 2025 at 9:25 AM
Reposted by Alberti Lab @ TU Dresden
Cell published a “Cell Line: 2014–2024,” which is a timeline highlighting a set of exceptional scientific works published in @cellpress.bsky.social. The timeline features a publication from the @hymanlab.bsky.social & @albertilab-tud.bsky.social from 2015. www.cell.com/cell/pdf/S00...
www.cell.com
February 4, 2025 at 1:33 PM
Reposted by Alberti Lab @ TU Dresden
Just finished this review by @alexholehouse.bsky.social & @albertilab-tud.bsky.social. Balanced, careful about overstatements or ambiguities, but also bold in making proposals as to how these things called condensates work, or how me might understand them, in an approximated but useful way, to work.
Molecular determinants of condensate composition
Cells use membraneless compartments to organize their interiors, and recent research has begun to uncover the molecular principles underlying their as…
www.sciencedirect.com
February 5, 2025 at 3:41 PM
We are looking forward to the workshop "Biomolecular Condensates and Polymer Phase Transitions" which we are organizing together with the IPF Dresden (dpd.ipfdd.de).

It will be held from May 25th - 28th, 2025 in Meißen, near Dresden.

The registration deadline is May 5th, 2025.
January 30, 2025 at 9:50 AM
Reposted by Alberti Lab @ TU Dresden
In the cover story of the February issue of @sciam.bsky.social I explain what biomolecular condensates are and why they are transforming cell biology. A short 🧵
(You'll need a subscription to read the article.)
www.scientificamerican.com/article/myst...
Mysterious Blobs in Cells Are Changing the Way We Understand Life
Tiny specks called biomolecular condensates are leading to a new understanding of the cell
www.scientificamerican.com
January 21, 2025 at 5:43 PM
Reposted by Alberti Lab @ TU Dresden
🎉 Our Master’s programs are accredited until 2032!

🧬 Regenerative Biology and Medicine
🔬 Molecular Bioengineering
🌌 Physics of Life

✅ The programs went through internal quality check at TU Dresden and passed with flying colors!

Applications open April 1!
More info ➡️ tud.link/ynf76g

#Masters #MSc
January 24, 2025 at 9:50 AM
Reposted by Alberti Lab @ TU Dresden
New review / perspective with @albertilab-tud.bsky.social on our thoughts on condensate speciality and recruitment, focusing on interplay between site specific and chemically specific interactions

www.cell.com/molecular-ce...
Molecular determinants of condensate composition
Biomolecular condensates are non-stochiometric assemblies that organize cellular matter in space and time. Despite much work, many questions remain regarding what determines the recruitment and exclus...
www.cell.com
January 17, 2025 at 10:23 AM