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Research at UHN
@uhnresearch.ca
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Research news from Canada's largest research hospital.
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Research at UHN @uhnresearch.ca · Nov 10
Driving Discovery. Delivering Impact.🎯

A story of science that’s bold, transformative, and collaborative.

This #WorldScienceDay, explore our annual research report and discover how @uhn.ca is building #AHealthierWorld.

➡️: www.uhnresearch.ca/Research-Rep...

#RR25 #DiscoveryToImpact
uhnresearch.ca
For #WorldCancerDay, see how a @pmresearch-uhn.bsky.social team developed a gene score to predict survival in myelofibrosis—a rare blood #cancer. Led by Drs. Jessie Medeiros, Andy Zeng, Vikas Gupta, and John Dick, this could help tailor treatment decisions.

🔗: pubmed.ncbi.nlm.nih.gov/41481381/
February 4, 2026 at 4:23 PM
Reposted by Research at UHN
pmresearch-uhn.bsky.social
“Keeping it hidden is dangerous. Being informed can save lives.”

Driven by a family loss, Dr. Razq Hakem @uhn.ca @uhnresearch.ca embarked on a research journey to understand the biology of BRCA mutations in breast and ovarian cancer.

www.youtube.com/watch?v=4yTT...
Meet Dr. Razq Hakem: Turning Family Loss to Lifesaving BRCA Discoveries | World Cancer Day 2026
YouTube video by UHN Research
www.youtube.com
February 3, 2026 at 8:58 PM
uhnresearch.ca
Small measurement errors can critically impact surgical outcomes.

Researchers from @tier-uhn.bsky.social are evaluating an AI-based digital ruler designed to support more accurate measurement during image-guided procedures.

🔗Read more: www.uhnresearch.ca/news/ai-meas...
February 2, 2026 at 4:15 PM
Reposted by Research at UHN
pmresearch-uhn.bsky.social
Our scientists at @uhn.ca Princess Margaret and BC Cancer discovered four new subtypes of Hodgkin lymphoma. One subtype with CSF2RB mutations creates an immune “shield”, but it can be reversed by JAK2 inhibitors, offering new treatment potential.

aacrjournals.org/cancerdiscov...
January 30, 2026 at 6:47 PM
uhnresearch.ca
🚨 New publication alert! Research from @uhn.ca reveals a mechanism behind why the immune system declines with age.

B cells—best known for producing antibodies—play a critical role in driving the aging of T cells, fighters of infection.

🔗 Read more: www.uhnresearch.ca/news/aging-a...
January 30, 2026 at 7:41 PM
uhnresearch.ca
Read about the latest findings from Canada’s largest #research hospital in @uhn.ca’s Research Spotlight newsletter:

▶️Psilocybin for treatment of #depression
▶️An #AI tool to analyze cardiac activity
▶️ Advancements in #Cancer immunotherapy
+ More

🔗: www.uhnresearch.ca/newsletter/r...
January 30, 2026 at 3:07 PM
uhnresearch.ca
Two very different kinds of innovation were recognized through @uhn.ca’s Mission Excellence Awards: a new direction in cancer research led by Dr. Pamela Ohashi, and HALO, a solution already changing how patients are protected every day.

🔗 Read more: www.uhnresearch.ca/news/researc...
January 29, 2026 at 7:13 PM
Reposted by Research at UHN
dkjei-uhn.bsky.social
The @dkjei-uhn.bsky.social January #newsletter has been released! Read about our recent events, new stories, features, awards and publications >> bit.ly/46nnOWv

@uhn.ca @uhnresearch.ca @kbi-uhn.bsky.social @schroeder-uhn.bsky.social @uoftmedicine.bsky.social
January 29, 2026 at 5:54 PM
uhnresearch.ca
Chronic pain affects 1 in 5 Canadians. ECHO Pain is a medical education program designed to equip clinicians with the skills and support needed to provide safer, more effective care.

➡️ @kiteuhn.bsky.social researchers review 10 years of its impact: www.uhnresearch.ca/news/echos-b...

#ChronicPain
January 29, 2026 at 3:34 PM
Reposted by Research at UHN
pmresearch-uhn.bsky.social
Congratulations to our Senior Scientist Dr. Pamela Ohashi on being named one of the Fellows of the AACR Academy Class of 2026 🎉.

www.aacr.org/about-the-aa...

@theaacr.bsky.social @uhnresearch.ca @uhn.ca
January 27, 2026 at 9:49 PM
uhnresearch.ca
New research from @kbi-uhn.bsky.social suggests #ChronicTraumaticEncephalopathy affects more than the brain.

People with repeated head impacts also show signs in the spinal cord—especially with age—reshaping how we understand trauma‑related neurodegeneration.

🔗: www.uhnresearch.ca/news/cost-im...
January 27, 2026 at 4:11 PM
uhnresearch.ca
(1/2) The Ontario Government has invested over $47M to support homegrown research across Ontario!

Congratulations to @uhn.ca's Drs. Mamatha Bhat, Daniel Winer, Jennifer Campos, George Mochizuki, Kamil Uludag & J. Rafael Montenegro Burke on receiving funding from the Ontario Research Fund. 🎉
January 26, 2026 at 8:46 PM
Reposted by Research at UHN
bhaibeka.bsky.social
LIGAND-AI led by @thesgc.bsky.social at @uhnresearch.ca and funded by the Innovative Health Initiative (IHI) with EU-Canada support, is officially launched!

My team will contribute AI expertise and will develop the AIRCHECK platform (aircheck.ai) for drug discovery.

www.thesgc.org/news/ihi-pro...
January 20, 2026 at 2:52 PM
uhnresearch.ca
A Canadian-led collaboration is leading a global initiative to transform drug discovery with #AI and #OpenScience! 🍁

@uhn.ca, @sickkidsto.bsky.social & @thesgc.bsky.social, are partnering on a $26M grant to support the LIGAND-AI Project—an international effort to advance precision medicine.⬇️
January 20, 2026 at 3:17 PM
uhnresearch.ca
Meet Sumaiyah Rehman, a Scientific Associate at @pmresearch-uhn.bsky.social and champion for #IDEA principles at UHN.

Read more about her inspiring work shepherding in better #cancer care and excellence in training, leadership, and culture.

🔗: www.uhnresearch.ca/news/sumaiya...

#TeamUHN @uhn.ca
January 19, 2026 at 7:03 PM
uhnresearch.ca
Researchers from @kbi-uhn.bsky.social are studying the potential of #psilocybin for #depression. Their early work represents an important step towards identifying whether this new drug has potential as a treatment for both mood and cognition.

🔗 Read more: www.uhnresearch.ca/news/fresh-w...

@uhn.ca
January 16, 2026 at 7:34 PM
uhnresearch.ca
The COVID-19 pandemic exposed aspects of surgical training that hinder surgical residents’ wellness. A new study from @tier-uhn.bsky.social explores these barriers and the need for more sustainable training environments.

🔗 Read more: www.uhnresearch.ca/news/surgica...

@uhn.ca @jmirpub.bsky.social
January 16, 2026 at 4:31 PM
uhnresearch.ca
A new @uhn.ca study shows that providing equipment, having minimal exclusions, and ensuring compatibility on any device can enable #RemoteManagementPrograms for #HeartFailure, like Medly, to provide more equitable access to care.

🔗 Read more: www.uhnresearch.ca/news/support...
January 14, 2026 at 4:44 PM
uhnresearch.ca
#ICYMI Two @uhn.ca researchers, Drs. Shaf Keshavjee and Allison McGeer, were among those honoured by the Order of Canada for their work advancing research in #transplantation and #InfectiousDisease worldwide. 🎖️🍁

🔗 Read more: www.uhnresearch.ca/news/nationa...

#OrderofCanada
January 13, 2026 at 4:18 PM
Reposted by Research at UHN
pmresearch-uhn.bsky.social
A study led by Dr. Sushant Kumar @uhn.ca @uhnresearch.ca investigated structural variants—large-scale DNA changes involving over 50 base pairs—and uncovered new insights into how they arise and their links to diseases like cancers and neurological disorders.

doi.org/10.1093/nar/...
January 12, 2026 at 2:47 PM
uhnresearch.ca
Researchers at @uhn.ca’s @pmresearch-uhn.bsky.social have found that inactivation of the TET2 gene can improve #cancer immunotherapy response—opening the door for more personalized treatment strategies.

🔗 Read more: www.uhnresearch.ca/news/linking...

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@uoftmedicine.bsky.social
January 6, 2026 at 8:16 PM
uhnresearch.ca
A collaborative @kbi-uhn.bsky.social & @uoftmedicine.bsky.social team has identified a biomarker linked to the inflammation that drives progressive #MultipleSclerosis. This is a step toward more precise diagnosis & treatment.

🔗️https://www.uhnresearch.ca/news/new-clues-multiple-sclerosis
January 2, 2026 at 4:44 PM
uhnresearch.ca
(1/3) 🎉 Congratulations to @uhn.ca researchers Drs. Shaf Keshavjee and Allison McGeer on their appointments to the Order of Canada! Their work has advanced research in #transplantation and #InfectiousDisease worldwide.

🔗 Read the full press release: gg.ca/en/media/new...
(Allison McGeer Image Source: Canadian Medical Hall of Fame).
December 31, 2025 at 6:25 PM
uhnresearch.ca
As 2025 comes to a close, we look forward to a new year full of opportunities to continue creating #AHealthierWorld.

Happy holidays from @uhnresearch.ca!
December 22, 2025 at 4:41 PM
uhnresearch.ca
A @uhn.ca study reveals gaps in #HepatitisC care for pregnant people.

Fewer than 10% of patients began treatment within 5 years of diagnosis, and many had multiple pregnancies before treatment. This highlights the need for stronger linkage-to-care.

🔗 Read more: doi.org/10.1093/cid/...
December 18, 2025 at 8:02 PM