Paul Knoepfler
@stemcells.bsky.social
Professor at UC Davis studying cancer & stem cell epigenomics. I also do outreach and blog The Niche http://ipscell.com Also stem cell YouTube channel http://cutt.ly/vcsev4J STAT column https://www.statnews.com/category/lab-dish-paul-knoepfler/
Pinned
Paul Knoepfler
@stemcells.bsky.social
· Jun 11
Top UC Davis Graduate Aims To Transform Experience of Aging
Only on annual visits to India was Avantika Gokulnatha able to help care for her now late grandfather as his health failed. But the San Jose resident endeavored to help others near her.Gokulnatha did ...
www.ucdavis.edu
Congrats to my student Avantika Gokulnatha on receiving @ucdavis.bsky.social the UC Davis University Medal as the top graduating senior this year. Out of something like 8000+ seniors! She's done some great research on H3.3 mutant glioma www.ucdavis.edu/news/top-uc-... Very proud of her
Weekly #stemcell & regenerative reads: The Atlantic stem cell advertorial, Ozempic & cartilage restoration surprise, dwarfism tx ipscell.com/2026/02/week... #stemcells
Weekly reads: The Atlantic stem cell advertorial, Ozempic & cartilage restoration surprise, dwarfism tx - The Niche
Weekly reads from biologist: The Atlantic stem cell ad-article, Ozempic & cartilage restoration surprise, dwarfism therapy.
ipscell.com
February 15, 2026 at 3:37 PM
Weekly #stemcell & regenerative reads: The Atlantic stem cell advertorial, Ozempic & cartilage restoration surprise, dwarfism tx ipscell.com/2026/02/week... #stemcells
ICYMI: Wyoming stem cell bill is latest risky, anti-FDA state legislation ipscell.com/2026/02/wyom... #stemcells #stemcell #FDA
Wyoming stem cell bill is latest risky, anti-FDA state legislation - The Niche
Stem cell biologist discusses a new Wyoming stem cell bill that is latest anti-FDA state legislation that poses risks to consumers.
ipscell.com
February 14, 2026 at 11:39 PM
ICYMI: Wyoming stem cell bill is latest risky, anti-FDA state legislation ipscell.com/2026/02/wyom... #stemcells #stemcell #FDA
Reposted by Paul Knoepfler
Ethics and Life Sciences Weekly Roundup | Ape Imagination, New Brain Neighborhoods, Attention, AI Health Advice Is Frequently Wrong, Hallucinating Robot Surgeons, Biological Data Governance, Risky Stem Cell Legislation, Indigenous Health Data Repository Funding Cut, + More mailchi.mp/jhu/sciencee...
Ethics and Life Sciences Weekly Roundup
mailchi.mp
February 12, 2026 at 3:14 PM
Ethics and Life Sciences Weekly Roundup | Ape Imagination, New Brain Neighborhoods, Attention, AI Health Advice Is Frequently Wrong, Hallucinating Robot Surgeons, Biological Data Governance, Risky Stem Cell Legislation, Indigenous Health Data Repository Funding Cut, + More mailchi.mp/jhu/sciencee...
Trump’s favorite polling group delivers devastating blow: America likes Joe Biden more www.independent.co.uk/news/world/a...
Trump’s top polling group delivers devastating blow: America likes Joe Biden more
Latest Rasmussen research likely to infuriate President Donald Trump by revealing almost half of voters think Democrat did a better job
www.independent.co.uk
February 12, 2026 at 5:29 PM
Trump’s favorite polling group delivers devastating blow: America likes Joe Biden more www.independent.co.uk/news/world/a...
Reposted by Paul Knoepfler
FDA OKs risky, pioneering OSK rejuvenation trial with David Sinclair's ER-100 ipscell.com/2026/02/fda-... The trial will test partially reprogramming in the diseased or injured eye. Was the time right? #stemcells #stemcell
FDA OKs risky, pioneering OSK rejuvenation trial with Sinclair's ER-100 - The Niche
Biologist discusses how the FDA has cleared a trial of ER-100 or OSK, Oct-4, Sox-2, and Klf-4 for eye rejuvenation.
ipscell.com
February 11, 2026 at 8:32 PM
FDA OKs risky, pioneering OSK rejuvenation trial with David Sinclair's ER-100 ipscell.com/2026/02/fda-... The trial will test partially reprogramming in the diseased or injured eye. Was the time right? #stemcells #stemcell
FDA OKs risky, pioneering OSK rejuvenation trial with David Sinclair's ER-100 ipscell.com/2026/02/fda-... The trial will test partially reprogramming in the diseased or injured eye. Was the time right? #stemcells #stemcell
FDA OKs risky, pioneering OSK rejuvenation trial with Sinclair's ER-100 - The Niche
Biologist discusses how the FDA has cleared a trial of ER-100 or OSK, Oct-4, Sox-2, and Klf-4 for eye rejuvenation.
ipscell.com
February 11, 2026 at 8:32 PM
FDA OKs risky, pioneering OSK rejuvenation trial with David Sinclair's ER-100 ipscell.com/2026/02/fda-... The trial will test partially reprogramming in the diseased or injured eye. Was the time right? #stemcells #stemcell
Reposted by Paul Knoepfler
You know what they’re going to store in those warehouses?
People
People
In the last month ICE has bought warehouses in:
- Hagerstown, MD: $102 million
- Surprise, AZ: $70 million
- Hamburg, PA: $87 million
- Tremont, PA: $120 million
- San Antonio, TX: $82 million
- El Paso, TX: $123 million
- Social Circle, GA: price unknown
This is unprecedented.
- Hagerstown, MD: $102 million
- Surprise, AZ: $70 million
- Hamburg, PA: $87 million
- Tremont, PA: $120 million
- San Antonio, TX: $82 million
- El Paso, TX: $123 million
- Social Circle, GA: price unknown
This is unprecedented.
February 9, 2026 at 6:46 PM
You know what they’re going to store in those warehouses?
People
People
Reposted by Paul Knoepfler
Weekly #stemcell & regenerative reads: surprise Casgevy challenge, India bars stem cells for autism, Dorothy Bishop PubPeer analysis ipscell.com/2026/02/week... #stemcells
Weekly reads: surprise Casgevy challenge, India bars stem cells for autism, Dorothy Bishop PubPeer analysis - The Niche
Stem cell biologist discusses recent developments including an unexpected Casgevy challenge and India barring stem cells for autism.
ipscell.com
February 8, 2026 at 2:59 PM
Weekly #stemcell & regenerative reads: surprise Casgevy challenge, India bars stem cells for autism, Dorothy Bishop PubPeer analysis ipscell.com/2026/02/week... #stemcells
My new piece @ScienceBasedMed: The peptide craze sweeping America has a fan in RFK Jr sciencebasedmedicine.org/the-peptide-... Look for the FDA under pressure to open the door again to compounding boosting risks to the public #peptides
The peptide craze sweeping America has a fan in RFK Jr
This could lead to less FDA oversight just when more is needed
sciencebasedmedicine.org
February 9, 2026 at 5:07 PM
My new piece @ScienceBasedMed: The peptide craze sweeping America has a fan in RFK Jr sciencebasedmedicine.org/the-peptide-... Look for the FDA under pressure to open the door again to compounding boosting risks to the public #peptides
Weekly #stemcell & regenerative reads: surprise Casgevy challenge, India bars stem cells for autism, Dorothy Bishop PubPeer analysis ipscell.com/2026/02/week... #stemcells
Weekly reads: surprise Casgevy challenge, India bars stem cells for autism, Dorothy Bishop PubPeer analysis - The Niche
Stem cell biologist discusses recent developments including an unexpected Casgevy challenge and India barring stem cells for autism.
ipscell.com
February 8, 2026 at 2:59 PM
Weekly #stemcell & regenerative reads: surprise Casgevy challenge, India bars stem cells for autism, Dorothy Bishop PubPeer analysis ipscell.com/2026/02/week... #stemcells
Reposted by Paul Knoepfler
Hims, other telehealth platforms push multi-cancer detection tests before evidence of benefit www.statnews.com/2026/02/06/t... via @statnews.com
Hims, other telehealth platforms push multi-cancer detection tests before evidence of benefit
Test makers and telehealth providers say they want to give people a chance to catch cancers early and seek treatment.
www.statnews.com
February 7, 2026 at 4:05 AM
Hims, other telehealth platforms push multi-cancer detection tests before evidence of benefit www.statnews.com/2026/02/06/t... via @statnews.com
Reposted by Paul Knoepfler
The list of things to avoid in russia widens: bathtubs now join tea and windows.
"The former official's body was discovered in the bathtub, and the preliminary cause of death is drowning. The state agency emphasizes that criminal activity is not being considered in his death"😬
"The former official's body was discovered in the bathtub, and the preliminary cause of death is drowning. The state agency emphasizes that criminal activity is not being considered in his death"😬
February 6, 2026 at 6:48 PM
The list of things to avoid in russia widens: bathtubs now join tea and windows.
"The former official's body was discovered in the bathtub, and the preliminary cause of death is drowning. The state agency emphasizes that criminal activity is not being considered in his death"😬
"The former official's body was discovered in the bathtub, and the preliminary cause of death is drowning. The state agency emphasizes that criminal activity is not being considered in his death"😬
Reposted by Paul Knoepfler
America: where you can sell a random “wellness” drink at CVS, claim it “may” somehow “reinforce” your immune system, and literally call it “The Flu Shot.”
February 5, 2026 at 1:56 AM
America: where you can sell a random “wellness” drink at CVS, claim it “may” somehow “reinforce” your immune system, and literally call it “The Flu Shot.”
Reposted by Paul Knoepfler
cc @usefulnoise.bsky.social
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@stemcells.bsky.social
@hankgreely.bsky.social
@cave-malum.bsky.social
@ethicselizabeth.bsky.social
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@wrigleyfield.bsky.social
@rwidome.bsky.social
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@hollylynchez.bsky.social
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Live from the heart of ICE-occupied Minneapolis, The Gated Community presents a free streaming concert of protest songs on Saturday, Feb 7 at 4 pm CST. All donations will go to the Immigrant Law Center of Minnesota.
Link for the live stream:
thegatedcommunityband.com/live-stream
Link for the live stream:
thegatedcommunityband.com/live-stream
The Gated Community - Live Stream
Guestbook for The Gated Community, an americana group from Minneapolis, MN - Post your message
thegatedcommunityband.com
February 5, 2026 at 2:27 AM
Reposted by Paul Knoepfler
Wyoming stem cell bill is latest risky, anti-FDA state legislation ipscell.com/2026/02/wyom... the so-called Stem Cell Freedom Act is a direct challenge to the FDA #stemcells #stemcell Joins other states like Florida but with some key differences
Wyoming stem cell bill is latest risky, anti-FDA state legislation - The Niche
Stem cell biologist discusses a new Wyoming stem cell bill that is latest anti-FDA state legislation that poses risks to consumers.
ipscell.com
February 4, 2026 at 4:09 PM
Wyoming stem cell bill is latest risky, anti-FDA state legislation ipscell.com/2026/02/wyom... the so-called Stem Cell Freedom Act is a direct challenge to the FDA #stemcells #stemcell Joins other states like Florida but with some key differences
Wyoming stem cell bill is latest risky, anti-FDA state legislation ipscell.com/2026/02/wyom... the so-called Stem Cell Freedom Act is a direct challenge to the FDA #stemcells #stemcell Joins other states like Florida but with some key differences
Wyoming stem cell bill is latest risky, anti-FDA state legislation - The Niche
Stem cell biologist discusses a new Wyoming stem cell bill that is latest anti-FDA state legislation that poses risks to consumers.
ipscell.com
February 4, 2026 at 4:09 PM
Wyoming stem cell bill is latest risky, anti-FDA state legislation ipscell.com/2026/02/wyom... the so-called Stem Cell Freedom Act is a direct challenge to the FDA #stemcells #stemcell Joins other states like Florida but with some key differences
Reposted by Paul Knoepfler
This cannot be something a civilian law enforcement agent is allowed to wear in the US — and an agency that has a culture that tolerates this cannot be saved.
Fucking surreal that people dressed like this and carrying assault rifles are permitted to kidnap people off our streets
February 4, 2026 at 12:53 AM
This cannot be something a civilian law enforcement agent is allowed to wear in the US — and an agency that has a culture that tolerates this cannot be saved.
Reposted by Paul Knoepfler
Weekly #regenerative & #stemcell reads: proposed human SCBEM framework, reporter self-injects peptides, ASD, organoids & NAMs ipscell.com/2026/02/week...
Weekly reads: human SCBEM framework, reporter self-injects peptides, ASD, NAMs - The Niche
Scientists sometimes disagree about research including not just what data might mean, but also what kinds of rules there should be about research like stem cell-based embryo models (SCBEM). It makes s...
ipscell.com
February 1, 2026 at 3:43 PM
Weekly #regenerative & #stemcell reads: proposed human SCBEM framework, reporter self-injects peptides, ASD, organoids & NAMs ipscell.com/2026/02/week...
Weekly #regenerative & #stemcell reads: proposed human SCBEM framework, reporter self-injects peptides, ASD, organoids & NAMs ipscell.com/2026/02/week...
Weekly reads: human SCBEM framework, reporter self-injects peptides, ASD, NAMs - The Niche
Scientists sometimes disagree about research including not just what data might mean, but also what kinds of rules there should be about research like stem cell-based embryo models (SCBEM). It makes s...
ipscell.com
February 1, 2026 at 3:43 PM
Weekly #regenerative & #stemcell reads: proposed human SCBEM framework, reporter self-injects peptides, ASD, organoids & NAMs ipscell.com/2026/02/week...
Reposted by Paul Knoepfler
His brief but fiery ruling chastised the government’s “ignorance of an American historical document called the Declaration of Independence”
www.nytimes.com/2026/01/31/u...
www.nytimes.com/2026/01/31/u...
Judge Orders Release of 5-Year-Old Whose Detention Drew Outrage
www.nytimes.com
January 31, 2026 at 10:55 PM
His brief but fiery ruling chastised the government’s “ignorance of an American historical document called the Declaration of Independence”
www.nytimes.com/2026/01/31/u...
www.nytimes.com/2026/01/31/u...
Reposted by Paul Knoepfler
Basically, we’re past Orban.
Steve Levitsky, the co-author of How Democracies Die, on the dangerous place we have reached as Trump escalates:
“Orbán doesn’t arrest journalists,” he said. “And in Hungary if you walk the streets of Budapest or other Hungarian cities, you will not find heavily armed masked men abducting people."
“Orbán doesn’t arrest journalists,” he said. “And in Hungary if you walk the streets of Budapest or other Hungarian cities, you will not find heavily armed masked men abducting people."
January 31, 2026 at 7:14 PM
Basically, we’re past Orban.
Reposted by Paul Knoepfler
His Stanford colleague and disinformation super spreader Ioannidis started these myths nearly 6 years ago.
Discussed in this novel.
sciencebasedmedicine.org/what-exactly...
Discussed in this novel.
sciencebasedmedicine.org/what-exactly...
January 31, 2026 at 6:15 PM
His Stanford colleague and disinformation super spreader Ioannidis started these myths nearly 6 years ago.
Discussed in this novel.
sciencebasedmedicine.org/what-exactly...
Discussed in this novel.
sciencebasedmedicine.org/what-exactly...
Reposted by Paul Knoepfler
I'm at the Willard Hotel where I've been denied entry and kicked out of the Reclaiming Science event with NIH director Bhattacharya & other top agency leaders.
@jocelynkaiser.bsky.social and I registered for the event months ago yet were told capacity was full, even as they let in dozens of others.
@jocelynkaiser.bsky.social and I registered for the event months ago yet were told capacity was full, even as they let in dozens of others.
January 30, 2026 at 6:07 PM
I'm at the Willard Hotel where I've been denied entry and kicked out of the Reclaiming Science event with NIH director Bhattacharya & other top agency leaders.
@jocelynkaiser.bsky.social and I registered for the event months ago yet were told capacity was full, even as they let in dozens of others.
@jocelynkaiser.bsky.social and I registered for the event months ago yet were told capacity was full, even as they let in dozens of others.
Reposted by Paul Knoepfler
In support of the Roman Reed Spinal Cord Injury Research Act ipscell.com/2026/01/in-s... #stemcells #stemcell
January 28, 2026 at 4:42 PM
In support of the Roman Reed Spinal Cord Injury Research Act ipscell.com/2026/01/in-s... #stemcells #stemcell
Reposted by Paul Knoepfler
The @washingtonpost.com, OTOH...not so much.
"Ilhan Omar should not have to fear for her safety to espouse her views, even if they are extreme." Less extreme (albeit in the other direction) than those of this Administration, the feet of whose boss the Post's owner is busy licking.
"Ilhan Omar should not have to fear for her safety to espouse her views, even if they are extreme." Less extreme (albeit in the other direction) than those of this Administration, the feet of whose boss the Post's owner is busy licking.
Total hero. Trump ought learn what tough and courageous mean from her behavior
"It shouldn’t take a willingness to court danger to run for office."
The latest from the Editorial Board: https://wapo.st/4k4ZjTH
The latest from the Editorial Board: https://wapo.st/4k4ZjTH
January 29, 2026 at 3:39 AM
The @washingtonpost.com, OTOH...not so much.
"Ilhan Omar should not have to fear for her safety to espouse her views, even if they are extreme." Less extreme (albeit in the other direction) than those of this Administration, the feet of whose boss the Post's owner is busy licking.
"Ilhan Omar should not have to fear for her safety to espouse her views, even if they are extreme." Less extreme (albeit in the other direction) than those of this Administration, the feet of whose boss the Post's owner is busy licking.