Paul Knoepfler
@stemcells.bsky.social
Professor at UC Davis studying cancer & stem cell epigenomics. I also do outreach and blog The Niche http://ipscell.com Also stem cell YouTube channel http://cutt.ly/vcsev4J STAT column https://www.statnews.com/category/lab-dish-paul-knoepfler/
Pinned
Paul Knoepfler
@stemcells.bsky.social
· Jun 11
Top UC Davis Graduate Aims To Transform Experience of Aging
Only on annual visits to India was Avantika Gokulnatha able to help care for her now late grandfather as his health failed. But the San Jose resident endeavored to help others near her.Gokulnatha did ...
www.ucdavis.edu
Congrats to my student Avantika Gokulnatha on receiving @ucdavis.bsky.social the UC Davis University Medal as the top graduating senior this year. Out of something like 8000+ seniors! She's done some great research on H3.3 mutant glioma www.ucdavis.edu/news/top-uc-... Very proud of her
Reposted by Paul Knoepfler
Extortion worked. Northwestern had not been able to draw down money on grants since April. Hemorrhaging money.
But the likely long-term consequences for NU and other schools is clear.
New mascot to replace the Wildcat: A tame cat with two broken kneecaps.
Mew…
But the likely long-term consequences for NU and other schools is clear.
New mascot to replace the Wildcat: A tame cat with two broken kneecaps.
Mew…
BREAKING: Northwestern University has agreed to pay the U.S. Treasury $75 million, over the course of three years as part of an agreement with the federal government to restore funding and end investigations into the university
Full statement from NU below:
Full statement from NU below:
November 29, 2025 at 2:11 AM
Extortion worked. Northwestern had not been able to draw down money on grants since April. Hemorrhaging money.
But the likely long-term consequences for NU and other schools is clear.
New mascot to replace the Wildcat: A tame cat with two broken kneecaps.
Mew…
But the likely long-term consequences for NU and other schools is clear.
New mascot to replace the Wildcat: A tame cat with two broken kneecaps.
Mew…
Fun, geeky turkey facts for the Thanksgiving dinner table ipscell.com/2020/11/top-...
Fun, geeky turkey facts for the Thanksgiving dinner table - The Niche
Americans eat tens of millions of turkeys each year on Thanksgiving....but what the heck is a turkey really? Here are geeky facts for the holiday.
ipscell.com
November 27, 2025 at 7:17 PM
Fun, geeky turkey facts for the Thanksgiving dinner table ipscell.com/2020/11/top-...
Pros & cons of dead celebrity genomics ipscell.com/2023/03/no-r... This trend just keeps on going... #genetics #ethics
Pros & cons of dead celebrity genomics - The Niche
Professor discusses ethical and scientific issues from novelty genomics like sequencing genomes of dead celebrities including sample sources
ipscell.com
November 27, 2025 at 4:30 PM
Pros & cons of dead celebrity genomics ipscell.com/2023/03/no-r... This trend just keeps on going... #genetics #ethics
Reposted by Paul Knoepfler
‼️‼️ Newly released emails show the FBI spent almost $1 million in overtime analyzing the Epstein files as part of an effort dubbed the “Special Redaction Project."
FBI’s Frantic Scramble to Redact Epstein Files Revealed
A trove of emails shows all-nighters and almost $1 million in overtime as Trumpworld debated releasing the Epstein files.
www.thedailybeast.com
November 27, 2025 at 3:51 AM
‼️‼️ Newly released emails show the FBI spent almost $1 million in overtime analyzing the Epstein files as part of an effort dubbed the “Special Redaction Project."
ICYMI: Firm marketing elective IVF for "genetic optimization" of babies via polygenic risk-type scoring is facing criticism; that arena faces unresolved ethical & technical questions too ipscell.com/2025/11/nucl... seems like a clear path to eugenics
Nucleus Genomics faces criticism as it and other firms promise embryo optimization despite unresolved scientific, ethical questions - The Niche
Stem cell biologist discusses how elective IVF firm Nucleus Genomics faces serious accusations including of plagiarism.
ipscell.com
November 26, 2025 at 3:58 PM
ICYMI: Firm marketing elective IVF for "genetic optimization" of babies via polygenic risk-type scoring is facing criticism; that arena faces unresolved ethical & technical questions too ipscell.com/2025/11/nucl... seems like a clear path to eugenics
Reposted by Paul Knoepfler
Nucleus Genomics faces criticism as it and other firms promise embryo optimization despite unresolved scientific, ethical questions ipscell.com/2025/11/nucl... elective IVF #stemcells
Nucleus Genomics faces criticism as it and other firms promise embryo optimization despite unresolved scientific, ethical questions - The Niche
Stem cell biologist discusses how elective IVF firm Nucleus Genomics faces serious accusations including of plagiarism.
ipscell.com
November 25, 2025 at 7:19 PM
Nucleus Genomics faces criticism as it and other firms promise embryo optimization despite unresolved scientific, ethical questions ipscell.com/2025/11/nucl... elective IVF #stemcells
Nucleus Genomics faces criticism as it and other firms promise embryo optimization despite unresolved scientific, ethical questions ipscell.com/2025/11/nucl... elective IVF #stemcells
Nucleus Genomics faces criticism as it and other firms promise embryo optimization despite unresolved scientific, ethical questions - The Niche
Stem cell biologist discusses how elective IVF firm Nucleus Genomics faces serious accusations including of plagiarism.
ipscell.com
November 25, 2025 at 7:19 PM
Nucleus Genomics faces criticism as it and other firms promise embryo optimization despite unresolved scientific, ethical questions ipscell.com/2025/11/nucl... elective IVF #stemcells
Reposted by Paul Knoepfler
So, um, maybe the time to put some guardrails up on the fertility industry was quite a while ago.
First, this from a Jan 30 article (link in alt).
First, this from a Jan 30 article (link in alt).
November 18, 2025 at 11:24 PM
So, um, maybe the time to put some guardrails up on the fertility industry was quite a while ago.
First, this from a Jan 30 article (link in alt).
First, this from a Jan 30 article (link in alt).
ICYMI: Weekly #stemcell & regenerative reads: FDA approves peptide therapy for Barth, other rare disease news, induced totipotency ipscell.com/2025/11/week... #stemcells
Weekly reads: FDA approves peptide therapy for Barth, other rare disease news, induced totipotency - The Niche
Professor discusses the week's regenerative news including FDA approves peptide therapy for Barth, mammoth RNA, & induced totipotency.
ipscell.com
November 24, 2025 at 8:18 PM
ICYMI: Weekly #stemcell & regenerative reads: FDA approves peptide therapy for Barth, other rare disease news, induced totipotency ipscell.com/2025/11/week... #stemcells
Reposted by Paul Knoepfler
Exciting news! We're honoring Rudolf Jaenisch with the 2025 Ogawa-Yamanaka Stem Cell Prize on December 1.
Join us as we celebrate his groundbreaking work in epigenetics and stem cell biology. Don't miss his scientific lecture! 🧬🔬
Register: https://bit.ly/4gNhf3z
Join us as we celebrate his groundbreaking work in epigenetics and stem cell biology. Don't miss his scientific lecture! 🧬🔬
Register: https://bit.ly/4gNhf3z
November 24, 2025 at 4:49 PM
Exciting news! We're honoring Rudolf Jaenisch with the 2025 Ogawa-Yamanaka Stem Cell Prize on December 1.
Join us as we celebrate his groundbreaking work in epigenetics and stem cell biology. Don't miss his scientific lecture! 🧬🔬
Register: https://bit.ly/4gNhf3z
Join us as we celebrate his groundbreaking work in epigenetics and stem cell biology. Don't miss his scientific lecture! 🧬🔬
Register: https://bit.ly/4gNhf3z
Reposted by Paul Knoepfler
I am not convinced any of these people knows what happens during a review
November 21, 2025 at 5:03 PM
I am not convinced any of these people knows what happens during a review
Reposted by Paul Knoepfler
Weekly #stemcell & regenerative reads: FDA approves peptide therapy for Barth Syndrome, other rare disease news, induced totipotency, more ipscell.com/2025/11/week... #stemcells
Weekly reads: FDA approves peptide therapy for Barth, other rare disease news, induced totipotency - The Niche
Professor discusses the week's regenerative news including FDA approves peptide therapy for Barth, mammoth RNA, & induced totipotency.
ipscell.com
November 23, 2025 at 3:05 PM
Weekly #stemcell & regenerative reads: FDA approves peptide therapy for Barth Syndrome, other rare disease news, induced totipotency, more ipscell.com/2025/11/week... #stemcells
Reposted by Paul Knoepfler
Had an amazing visit to the NIEHS to present the lab's research. The depth of expertise in #epigenetics and chromatin biology there is remarkable. Big thanks to @jxhoffman.bsky.social for hosting me. 🧪
November 22, 2025 at 2:17 PM
Had an amazing visit to the NIEHS to present the lab's research. The depth of expertise in #epigenetics and chromatin biology there is remarkable. Big thanks to @jxhoffman.bsky.social for hosting me. 🧪
Reposted by Paul Knoepfler
Weekly #stemcell & regenerative reads: FDA approves peptide therapy for Barth Syndrome, other rare disease news, induced totipotency, more ipscell.com/2025/11/week... #stemcells
Weekly reads: FDA approves peptide therapy for Barth, other rare disease news, induced totipotency - The Niche
Professor discusses the week's regenerative news including FDA approves peptide therapy for Barth, mammoth RNA, & induced totipotency.
ipscell.com
November 23, 2025 at 3:05 PM
Weekly #stemcell & regenerative reads: FDA approves peptide therapy for Barth Syndrome, other rare disease news, induced totipotency, more ipscell.com/2025/11/week... #stemcells
Updated 2025 List of FDA-Approved Cell and Gene Therapies ipscell.com/2025/01/upda... #stemcells
Updated 2025 List of FDA-Approved Cell and Gene Therapies - The Niche
Professor's list of FDA-approved cell and gene therapies including stem cell therapies that have received FDA approval.
ipscell.com
November 22, 2025 at 10:42 PM
Updated 2025 List of FDA-Approved Cell and Gene Therapies ipscell.com/2025/01/upda... #stemcells
Reposted by Paul Knoepfler
Weekly #stemcell & regenerative reads: thoughts on MAHA summit agenda, Ittleman on FL stem cell law, NYT on brain organoids, Dr. BS letters to the editor ipscell.com/2025/11/week... #stemcells
Weekly reads: MAHA summit, Ittleman on FL stem cell law, NYT on brain organoids, Dr. BS - The Niche
Stem cell biologist discusses the week's news on regenerative medicine including more on peptides and the MAHA summit.
ipscell.com
November 16, 2025 at 3:31 PM
Weekly #stemcell & regenerative reads: thoughts on MAHA summit agenda, Ittleman on FL stem cell law, NYT on brain organoids, Dr. BS letters to the editor ipscell.com/2025/11/week... #stemcells
Reposted by Paul Knoepfler
Khloé & Kim Kardashian stem cell adventures in Mexico, getting MUSE cells raise many concerns for the field & public health ipscell.com/2025/11/khlo... #stemcells #stemcell
Khloé & Kim Kardashian stem cell adventures in Mexico, MUSE cells raise concerns - The Niche
Cell biologist discusses Khloé & Kim Kardashian stem cell injections in Mexico and the major risks this entails including to the public.
ipscell.com
November 19, 2025 at 6:56 PM
Khloé & Kim Kardashian stem cell adventures in Mexico, getting MUSE cells raise many concerns for the field & public health ipscell.com/2025/11/khlo... #stemcells #stemcell
Reposted by Paul Knoepfler
No more paylines at the NIH
grants.nih.gov/news-events/...
grants.nih.gov/news-events/...
Implementing a Unified NIH Funding Strategy to Guide Consistent and Clearer Award Decisions | Grants & Funding
grants.nih.gov
November 21, 2025 at 7:45 PM
No more paylines at the NIH
grants.nih.gov/news-events/...
grants.nih.gov/news-events/...
This is not making America healthier but quite the opposite.
Halted NIH Clinical Trials List Reveals Slashed Treatments for Cancer, COVID and Minority Health
www.scientificamerican.com/article/halt...
Sickle cell disease, sleep disorders and lung cancer & much more
A dive into the list of NIH's 383 shelved clinical trials, obtained by Scientific American
www.scientificamerican.com/article/halt...
Sickle cell disease, sleep disorders and lung cancer & much more
A dive into the list of NIH's 383 shelved clinical trials, obtained by Scientific American
Halted NIH Clinical Trials List Reveals Slashed Treatments for Cancer, COVID and Minority Health
The National Institutes of Health has canceled funding for at least 383 clinical trials in the last year, affecting some 74,000 participants
www.scientificamerican.com
November 20, 2025 at 10:13 PM
This is not making America healthier but quite the opposite.
Reposted by Paul Knoepfler
New article explores 4,481 YouTube videos about stem cells to map how medical knowledge is shared online, revealing a complex discourse dominated by celebrity influencers in the promotion and discussion of putative stem cell treatments. https://ow.ly/iNUG50Xv8Ay
November 20, 2025 at 10:04 PM
New article explores 4,481 YouTube videos about stem cells to map how medical knowledge is shared online, revealing a complex discourse dominated by celebrity influencers in the promotion and discussion of putative stem cell treatments. https://ow.ly/iNUG50Xv8Ay
Reposted by Paul Knoepfler
"Neither MUSE cells or VSELs have been proven helpful or safe for any health condition."
How can one prove that for something which doesn't exist?
forbetterscience.com/2023/06/21/s...
How can one prove that for something which doesn't exist?
forbetterscience.com/2023/06/21/s...
November 20, 2025 at 12:14 PM
"Neither MUSE cells or VSELs have been proven helpful or safe for any health condition."
How can one prove that for something which doesn't exist?
forbetterscience.com/2023/06/21/s...
How can one prove that for something which doesn't exist?
forbetterscience.com/2023/06/21/s...
Reposted by Paul Knoepfler
ICYMI: So-called regenerative or wellness "peptides" could be the latest big scam. Their use is spreading like wildfire and it's unclear whether the current FDA will do more to lower risks here or under RFK Jr. just make it worse ipscell.com/2025/11/more...
More red flags on peptides even as softening of FDA oversight could happen soon under RFK Jr. - The Niche
Stem cell biologist discusses how Peptides are the next big scam unfolding now in the regenerative medicine and alternative medicine arenas.
ipscell.com
November 13, 2025 at 8:52 PM
ICYMI: So-called regenerative or wellness "peptides" could be the latest big scam. Their use is spreading like wildfire and it's unclear whether the current FDA will do more to lower risks here or under RFK Jr. just make it worse ipscell.com/2025/11/more...
Khloé & Kim Kardashian stem cell adventures in Mexico, getting MUSE cells raise many concerns for the field & public health ipscell.com/2025/11/khlo... #stemcells #stemcell
Khloé & Kim Kardashian stem cell adventures in Mexico, MUSE cells raise concerns - The Niche
Cell biologist discusses Khloé & Kim Kardashian stem cell injections in Mexico and the major risks this entails including to the public.
ipscell.com
November 19, 2025 at 6:56 PM
Khloé & Kim Kardashian stem cell adventures in Mexico, getting MUSE cells raise many concerns for the field & public health ipscell.com/2025/11/khlo... #stemcells #stemcell