@rachidtahzima.bsky.social
Virologist & Assistant Professor / Evolutionary Computational Structural Biology & Artificial Intelligence / One Health Virology 🦠@IBSquare/VUB
A significant contribution to the dinoflagellate virology. Among the notable modular features of PelV-1 are unique micron-length tail proteins, phagocytosis-like entry mechanism and its varied auxiliary proteins including photosynthesis and energy-fuelling machine 🤯 🦠
doi.org/10.1101/2025...
doi.org/10.1101/2025...
A dinoflagellate-infecting giant virus with a micron-length tail
Viral infection is a ubiquitous source of marine plankton mortality, but relatively few viruses that infect phytoplankton have been characterized. Here we describe a virus, PelV-1, with unusual morpho...
doi.org
August 6, 2025 at 2:28 PM
A significant contribution to the dinoflagellate virology. Among the notable modular features of PelV-1 are unique micron-length tail proteins, phagocytosis-like entry mechanism and its varied auxiliary proteins including photosynthesis and energy-fuelling machine 🤯 🦠
doi.org/10.1101/2025...
doi.org/10.1101/2025...
Sons of Carolus Von Linnaeus !🤭
Science remains an Anarchic Process
thebiologist.rsb.org.uk/biologist-fe...
Science remains an Anarchic Process
thebiologist.rsb.org.uk/biologist-fe...
Taxonomic trolling
26 May 2025
Darren Naish looks at how a small number of authors can cause chaos in biology’s system for naming species and what can be done about it
The term ‘taxonomy’ refers to the branch of sc...
thebiologist.rsb.org.uk
July 17, 2025 at 10:25 AM
Sons of Carolus Von Linnaeus !🤭
Science remains an Anarchic Process
thebiologist.rsb.org.uk/biologist-fe...
Science remains an Anarchic Process
thebiologist.rsb.org.uk/biologist-fe...
🤓 Wounderfull Research Article with a « Compendium » of new interesting domains in new viruses… very Similar and Complementary to our Modulome Biophysics Approach … Big Congrats🥇🖖🏼
doi.org/10.1128/mbio...
doi.org/10.1128/mbio...
The protein structurome of Orthornavirae and its dark matter | mBio
Advanced methods for protein structure prediction, such as AlphaFold2, greatly expand
our capability to identify protein domains and infer their likely functions and evolutionary
relationships. This i...
doi.org
July 16, 2025 at 4:30 PM
🤓 Wounderfull Research Article with a « Compendium » of new interesting domains in new viruses… very Similar and Complementary to our Modulome Biophysics Approach … Big Congrats🥇🖖🏼
doi.org/10.1128/mbio...
doi.org/10.1128/mbio...
Researchers discovered 20 new bat viruses, including closely related to deadly Nipah/Hendra viruses, in bats. henipaviruses were found in fruit bats near human-populated areas, raising concerns about potential spillover risks. Further lab studies needed. 🦠🦠🦠
doi.org/10.1371/jour...
doi.org/10.1371/jour...
Infectome analysis of bat kidneys from Yunnan province, China, reveals novel henipaviruses related to Hendra and Nipah viruses and prevalent bacterial and eukaryotic microbes
Author summary Although extensive investigations have been conducted on the bat virome, most studies have focused on fecal samples, leaving other tissues, such as the kidney, largely unexplored. Howev...
doi.org
June 25, 2025 at 4:49 PM
Researchers discovered 20 new bat viruses, including closely related to deadly Nipah/Hendra viruses, in bats. henipaviruses were found in fruit bats near human-populated areas, raising concerns about potential spillover risks. Further lab studies needed. 🦠🦠🦠
doi.org/10.1371/jour...
doi.org/10.1371/jour...
RdRpzzz… at your marks 🤯🦠
“Microbe with bizarrely tiny genome may be evolving into a virus
With DNA focused almost entirely on replication, newly discovered organism blurs the line between cells and viruses”
doi:10.1126/science.z7ekqxv
“Microbe with bizarrely tiny genome may be evolving into a virus
With DNA focused almost entirely on replication, newly discovered organism blurs the line between cells and viruses”
doi:10.1126/science.z7ekqxv
www.biorxiv.org
June 18, 2025 at 9:49 AM
RdRpzzz… at your marks 🤯🦠
“Microbe with bizarrely tiny genome may be evolving into a virus
With DNA focused almost entirely on replication, newly discovered organism blurs the line between cells and viruses”
doi:10.1126/science.z7ekqxv
“Microbe with bizarrely tiny genome may be evolving into a virus
With DNA focused almost entirely on replication, newly discovered organism blurs the line between cells and viruses”
doi:10.1126/science.z7ekqxv
Reposted
Think coronavirus spikes have run out of surprises? Think again.
Our latest preprint dives into the highly unusual spikes of marine mammal coronaviruses.
www.biorxiv.org/content/10.1...
This #cryoEM study was led by @viralfusion.bsky.social, with key contributions from an amazing team.
Our latest preprint dives into the highly unusual spikes of marine mammal coronaviruses.
www.biorxiv.org/content/10.1...
This #cryoEM study was led by @viralfusion.bsky.social, with key contributions from an amazing team.
May 23, 2025 at 5:02 AM
Think coronavirus spikes have run out of surprises? Think again.
Our latest preprint dives into the highly unusual spikes of marine mammal coronaviruses.
www.biorxiv.org/content/10.1...
This #cryoEM study was led by @viralfusion.bsky.social, with key contributions from an amazing team.
Our latest preprint dives into the highly unusual spikes of marine mammal coronaviruses.
www.biorxiv.org/content/10.1...
This #cryoEM study was led by @viralfusion.bsky.social, with key contributions from an amazing team.
Reposted
Protein sequencing on desktop sequencer maybe possible soon ?! 🤯🤯
Multi-pass, single-molecule nanopore reading of long protein strands - Nature
A technique for threading long protein strands through a nanopore by electrophoresis and back using a protein unfoldase motor, ClpX, enables single protein molecules to be analyzed multiple times with...
www.nature.com
May 22, 2025 at 4:20 PM
Protein sequencing on desktop sequencer maybe possible soon ?! 🤯🤯
arxiv.org
May 23, 2025 at 1:52 AM
Reposted
Wellcome Genome campus started to feel like home :)
back for some bioinformatics talks, information, discussions... on microbes and public health. #ABPHM25
last week: info on RNA viruses, then: all viruses at ViBioM2025, today: microbes :)
🎊 90 countries >600 attendees!
Science is global! 🌏🌍🌎
back for some bioinformatics talks, information, discussions... on microbes and public health. #ABPHM25
last week: info on RNA viruses, then: all viruses at ViBioM2025, today: microbes :)
🎊 90 countries >600 attendees!
Science is global! 🌏🌍🌎
May 21, 2025 at 1:05 PM
Wellcome Genome campus started to feel like home :)
back for some bioinformatics talks, information, discussions... on microbes and public health. #ABPHM25
last week: info on RNA viruses, then: all viruses at ViBioM2025, today: microbes :)
🎊 90 countries >600 attendees!
Science is global! 🌏🌍🌎
back for some bioinformatics talks, information, discussions... on microbes and public health. #ABPHM25
last week: info on RNA viruses, then: all viruses at ViBioM2025, today: microbes :)
🎊 90 countries >600 attendees!
Science is global! 🌏🌍🌎
Reposted
Anatomy, Ecology and Virology of these Amazing 🦠 - Spyros You Rocked Those GPs - @spyroslytras.bsky.social 😉
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Mapping glycoprotein structure reveals Flaviviridae evolutionary history - Nature
Combined phylogenetic analyses and glycoprotein structure prediction across the Flaviviridae reveals divergent membrane fusion systems and provides insights into the complex evolutionary history withi...
www.nature.com
May 17, 2025 at 12:01 PM
Anatomy, Ecology and Virology of these Amazing 🦠 - Spyros You Rocked Those GPs - @spyroslytras.bsky.social 😉
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted
The CRISPR family’s most versatile member has made its medical debut: a cutting-edge gene-editing technique known as prime editing has been used to treat a person for the first time
https://go.nature.com/3YNta9V
https://go.nature.com/3YNta9V
World first: ultra-powerful CRISPR treatment trialled in a person
Immune-cell function improved in a teenager whose DNA was altered using prime editing.
go.nature.com
May 19, 2025 at 1:58 PM
The CRISPR family’s most versatile member has made its medical debut: a cutting-edge gene-editing technique known as prime editing has been used to treat a person for the first time
https://go.nature.com/3YNta9V
https://go.nature.com/3YNta9V
Reposted
Single cell transcriptomics correlate avian coronavirus prime vaccination efficacy with antigen-presenting cell preference
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Single cell transcriptomics correlate avian coronavirus prime vaccination efficacy with antigen-presenting cell preference - npj Vaccines
npj Vaccines - Single cell transcriptomics correlate avian coronavirus prime vaccination efficacy with antigen-presenting cell preference
www.nature.com
May 19, 2025 at 4:46 PM
Single cell transcriptomics correlate avian coronavirus prime vaccination efficacy with antigen-presenting cell preference
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted
Identification of naturally occurring drug-resistant mutations of SARS-CoV-2 papain-like protease
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Identification of naturally occurring drug-resistant mutations of SARS-CoV-2 papain-like protease - Nature Communications
This study identifies E167, Y268, and Q269 as drug-resistant hotspots for SARS-CoV papain-like protease inhibitors that bind to the BL2 loop and groove region, which are valuable in informing the desi...
www.nature.com
May 19, 2025 at 4:47 PM
Identification of naturally occurring drug-resistant mutations of SARS-CoV-2 papain-like protease
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Anatomy, Ecology and Virology of these Amazing 🦠 - Spyros You Rocked Those GPs - @spyroslytras.bsky.social 😉
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Mapping glycoprotein structure reveals Flaviviridae evolutionary history - Nature
Combined phylogenetic analyses and glycoprotein structure prediction across the Flaviviridae reveals divergent membrane fusion systems and provides insights into the complex evolutionary history withi...
www.nature.com
May 17, 2025 at 12:01 PM
Anatomy, Ecology and Virology of these Amazing 🦠 - Spyros You Rocked Those GPs - @spyroslytras.bsky.social 😉
www.nature.com/articles/s41...
www.nature.com/articles/s41...
One of the many reasons why this Second #RdRpSummit2025 in Lisabon will be remembered…🦠🧠🤓
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer
The neuronal protein Arc is evolutionarily related to retrotransposon Gag proteins
and forms virus-like capsid structures that can transfer mRNA between cells in the
nervous system.
www.cell.com
May 15, 2025 at 4:38 PM
One of the many reasons why this Second #RdRpSummit2025 in Lisabon will be remembered…🦠🧠🤓
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Reposted
Searching through uncharacterized proteins to find endogenous viral elements. You can read all about it here- doi.org/10.1101/2024...
Uncovering hundreds of exogenous and endogenous RNA viral RdRp sequences amongst uncharacterised sequences in public protein databases
Public databases of protein sequences, such as the National Center for Biotechnology Information (NCBI) Protein repository and UniProt, contain millions of proteins identified in samples from specific...
www.biorxiv.org
May 12, 2025 at 9:08 AM
Searching through uncharacterized proteins to find endogenous viral elements. You can read all about it here- doi.org/10.1101/2024...