PLMcCarthyBuffalo
@plmbuffalo.bsky.social
180 followers 270 following 120 posts
Translational Hematology Oncology Investigator, Roswell Park Comprehensive Cancer Center, Buffalo, NY
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Sad to hear about the sudden passing of Dr. Durie, who did so much for the treatment of #myeloma patients.
Reposted by PLMcCarthyBuffalo
Congratulations to the recipients of the Nobel Prize in Physiology or Medicine 2025 - Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi "for their discoveries concerning peripheral immune tolerance" including the identification of regulatory T cells

#NobelPrize #Tregs

@nobelprize.bsky.social 🧪🔬🏆
Reposted by PLMcCarthyBuffalo
Paola Neri presents data from her recent Blood Cancer Discovery paper, "Timing genomic antigen loss in multiple myeloma treated with T-cell redirecting immunotherapies" at #IMS25.

Read the article: buff.ly/vlQra5A
Reposted by PLMcCarthyBuffalo
Presented at #ATTR:

Gillmore and colleagues report 24-month results from a phase 1 study of nexiguran ziclumeran, a CRISPR gene-editing approach to treating hereditary transthyretin amyloidosis with polyneuropathy. Full study results: nej.md/46Qhur7

#MedSky #NeuroSky #Genetics
A graph showing the mean percentage change from baseline in transthyretin (TTR) levels after a single intravenous infusion of nexiguran ziclumeran (nex-z).
Reposted by PLMcCarthyBuffalo
The first leg of the #LSOE2025 tour is complete! 🧑‍🚀 Thanks to everyone who came out and a special thank you to Guster and Fastball for joining the tour. Sugar Ray and Fastball will be on for the second leg! Which show are you coming to? 🚀
Reposted by PLMcCarthyBuffalo
A letter from Rasmus and Carolina. 💙
Reposted by PLMcCarthyBuffalo
Inflammatory memory of stem cells: implications for hematologic diseases buff.ly/QBUFcjd #hemesky
Reposted by PLMcCarthyBuffalo
NGS improves MDS diagnosis, detecting somatic mutations in 75% and CNVs in 38% of patients. buff.ly/vB8idtQ #hemesky