Neha Ghosh
@nehaghosh.bsky.social
K99|R00 NEI, NIH Postdoctoral Fellow
Treisman Lab
NYU School of Medicine
Tissue patterning| Organ morphogenesis
#WomeninSTEM
Treisman Lab
NYU School of Medicine
Tissue patterning| Organ morphogenesis
#WomeninSTEM
Pinned
Neha Ghosh
@nehaghosh.bsky.social
· Aug 28
Corneal lens curvature depends on localized chitin secretion https://www.biorxiv.org/content/10.1101/2025.08.22.671854v1
🚨pre-print alert🚨
Excited to share the latest work on how cell specific secretion of chitin controls the shape of the fly corneal lens, an #aECM structure.
Excited to share the latest work on how cell specific secretion of chitin controls the shape of the fly corneal lens, an #aECM structure.
Reposted by Neha Ghosh
It was an honor being interviewed about our new color vision project by the 'Eye on Vision' WYPL Memphis radio show! 🪰👀🧪
@umassboston.bsky.social
eyeonvision.blogspot.com/2025/11/hmx-...
@umassboston.bsky.social
eyeonvision.blogspot.com/2025/11/hmx-...
Hmx Protein's Effect On Fruit Flies' Photoreceptors and Info On The NFB Performing Arts Division
Dr. Jens Rister (University of Massachusetts - Boston) Katelyn MacIntyre (National Federation of the Blind Performing Arts Division - Baltim...
eyeonvision.blogspot.com
November 27, 2025 at 4:41 PM
It was an honor being interviewed about our new color vision project by the 'Eye on Vision' WYPL Memphis radio show! 🪰👀🧪
@umassboston.bsky.social
eyeonvision.blogspot.com/2025/11/hmx-...
@umassboston.bsky.social
eyeonvision.blogspot.com/2025/11/hmx-...
Reposted by Neha Ghosh
My lab @poldresden.bsky.social is now CLOSED! The fabulous @sanikajah.bsky.social has left (defense soon). The lab @mbisg.bsky.social in SG is now 1yr old and growing!
PhD students apply here (Jan 12): www.mbi.nus.edu.sg/education/gr...
Undergrads (Jan 31): www.mbi.nus.edu.sg/education/mu...
PhD students apply here (Jan 12): www.mbi.nus.edu.sg/education/gr...
Undergrads (Jan 31): www.mbi.nus.edu.sg/education/mu...
November 28, 2025 at 2:51 AM
My lab @poldresden.bsky.social is now CLOSED! The fabulous @sanikajah.bsky.social has left (defense soon). The lab @mbisg.bsky.social in SG is now 1yr old and growing!
PhD students apply here (Jan 12): www.mbi.nus.edu.sg/education/gr...
Undergrads (Jan 31): www.mbi.nus.edu.sg/education/mu...
PhD students apply here (Jan 12): www.mbi.nus.edu.sg/education/gr...
Undergrads (Jan 31): www.mbi.nus.edu.sg/education/mu...
Reposted by Neha Ghosh
New paper from the @rouxlab.bsky.social on Nature Communications! We study how membrane tension is spatially organized in cells. Using the mechanosensitive probe Flipper-TR to visualize tension across the plasma membrane of adherent cells and to dissect the conditions needed for a gradient to happen
November 27, 2025 at 2:14 PM
New paper from the @rouxlab.bsky.social on Nature Communications! We study how membrane tension is spatially organized in cells. Using the mechanosensitive probe Flipper-TR to visualize tension across the plasma membrane of adherent cells and to dissect the conditions needed for a gradient to happen
Reposted by Neha Ghosh
2/2 If you’re into #cellbio, cellular interfaces, #mechanobiology, #membranes, anything related, come to Münster, Germany, May 27–29!
www.uni-muenster.de/SFB1348/en/i...
Please spread the word. It’s a fantastic (and FREE!) meeting. And while you’re here, explore Münster… it’s worth it.
#Science
www.uni-muenster.de/SFB1348/en/i...
Please spread the word. It’s a fantastic (and FREE!) meeting. And while you’re here, explore Münster… it’s worth it.
#Science
November 28, 2025 at 8:34 AM
2/2 If you’re into #cellbio, cellular interfaces, #mechanobiology, #membranes, anything related, come to Münster, Germany, May 27–29!
www.uni-muenster.de/SFB1348/en/i...
Please spread the word. It’s a fantastic (and FREE!) meeting. And while you’re here, explore Münster… it’s worth it.
#Science
www.uni-muenster.de/SFB1348/en/i...
Please spread the word. It’s a fantastic (and FREE!) meeting. And while you’re here, explore Münster… it’s worth it.
#Science
Reposted by Neha Ghosh
Ditipriya Mallick, Siddhartha Sankar Jana and colleagues discover that cellular elasticity drives mechano-adaptation against fluid shear stress.
journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
November 27, 2025 at 8:04 AM
Ditipriya Mallick, Siddhartha Sankar Jana and colleagues discover that cellular elasticity drives mechano-adaptation against fluid shear stress.
journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
Reposted by Neha Ghosh
Despite advances in #ProximityLabeling tools, we can't capture intermediary proteins that bridge two associated non-interacting proteins. STUPPIT is a novel method to label intermediary proteins between two non-interacting partners in signaling pathways @plosbiology.org 🧪 plos.io/4ab6YwQ
November 27, 2025 at 8:55 AM
Despite advances in #ProximityLabeling tools, we can't capture intermediary proteins that bridge two associated non-interacting proteins. STUPPIT is a novel method to label intermediary proteins between two non-interacting partners in signaling pathways @plosbiology.org 🧪 plos.io/4ab6YwQ
Reposted by Neha Ghosh
So called microtubule organizing centers (MTOCs) are not "organizing centers". They don't control their position (network center), nor MT orientation, length and shape (network shape). The actual organizers are MTs, molecular motors and regulators of MT +ends. MTOCs nucleate MTs.
Let's rename MTOCs.
Let's rename MTOCs.
November 27, 2025 at 8:47 AM
So called microtubule organizing centers (MTOCs) are not "organizing centers". They don't control their position (network center), nor MT orientation, length and shape (network shape). The actual organizers are MTs, molecular motors and regulators of MT +ends. MTOCs nucleate MTs.
Let's rename MTOCs.
Let's rename MTOCs.
Prospective PhD students if you are looking to work on some exciting Developmental Biology questions combining some state-of-the-art microscopy, please consider joining the talented @maikbischoff.bsky.social
So excited to share this as a new junior PI:
My brand-new lab website! 🎉🪰🌀
www.bischofflab.com
Please pass it on to young, motivated researchers looking for PhD positions 😊
And for the #FluorescenceFriday community: don’t miss the SciArt Gallery!
#CellBio #DevBio #PhDjob #PhDposition #Science
My brand-new lab website! 🎉🪰🌀
www.bischofflab.com
Please pass it on to young, motivated researchers looking for PhD positions 😊
And for the #FluorescenceFriday community: don’t miss the SciArt Gallery!
#CellBio #DevBio #PhDjob #PhDposition #Science
November 27, 2025 at 2:30 PM
Prospective PhD students if you are looking to work on some exciting Developmental Biology questions combining some state-of-the-art microscopy, please consider joining the talented @maikbischoff.bsky.social
Reposted by Neha Ghosh
New @pnas.org
"This work represents the most extensive study to
date regarding the effect of tattoo ink on the immune response and raises serious health concerns associated with the tattooing" including reduced response to Covid vaccination
www.pnas.org/doi/10.1073/...
"This work represents the most extensive study to
date regarding the effect of tattoo ink on the immune response and raises serious health concerns associated with the tattooing" including reduced response to Covid vaccination
www.pnas.org/doi/10.1073/...
Tattoo ink induces inflammation in the draining lymph node and alters the immune response to vaccination | PNAS
Despite safety concerns regarding the toxicity of tattoo ink, no studies have reported
the consequences of tattooing on the immune response. In thi...
www.pnas.org
November 25, 2025 at 7:35 PM
New @pnas.org
"This work represents the most extensive study to
date regarding the effect of tattoo ink on the immune response and raises serious health concerns associated with the tattooing" including reduced response to Covid vaccination
www.pnas.org/doi/10.1073/...
"This work represents the most extensive study to
date regarding the effect of tattoo ink on the immune response and raises serious health concerns associated with the tattooing" including reduced response to Covid vaccination
www.pnas.org/doi/10.1073/...
Reposted by Neha Ghosh
Check out my Perspective article “The Retina’s Rhythm” which accompanies an exciting paper by Claude Desplan in Science. I highlight his discovery that waves of calcium are required to finalize the honeycomb-like structure of the Drosophila retina.
www.science.org/doi/epdf/10....
www.science.org/doi/epdf/10....
The retina’s rhythm
Calcium waves facilitate the emergence of sight
www.science.org
November 21, 2025 at 2:00 PM
Check out my Perspective article “The Retina’s Rhythm” which accompanies an exciting paper by Claude Desplan in Science. I highlight his discovery that waves of calcium are required to finalize the honeycomb-like structure of the Drosophila retina.
www.science.org/doi/epdf/10....
www.science.org/doi/epdf/10....
Reposted by Neha Ghosh
Super proud to be part of SFB1348 — and excited to share that I now officially have my own lab in Münster! 🎉🪰
We’ll study #cellbio & #morphogenesis, focusing on organ sculpting and #chirality in #Drosophila.
I’ll soon hire my first #PhD student — feel free to reach out!
#juniorPI #Science #devbio
We’ll study #cellbio & #morphogenesis, focusing on organ sculpting and #chirality in #Drosophila.
I’ll soon hire my first #PhD student — feel free to reach out!
#juniorPI #Science #devbio
November 25, 2025 at 3:57 PM
Super proud to be part of SFB1348 — and excited to share that I now officially have my own lab in Münster! 🎉🪰
We’ll study #cellbio & #morphogenesis, focusing on organ sculpting and #chirality in #Drosophila.
I’ll soon hire my first #PhD student — feel free to reach out!
#juniorPI #Science #devbio
We’ll study #cellbio & #morphogenesis, focusing on organ sculpting and #chirality in #Drosophila.
I’ll soon hire my first #PhD student — feel free to reach out!
#juniorPI #Science #devbio
Well deserved, Ben! 🎉
Congrats Ben, Claude, et al! A beautiful characterization of roles of Ca++ waves and gap junction functions in tissue patterning!
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Retinal calcium waves coordinate uniform tissue patterning of the Drosophila eye
Optimal neural processing relies on precise tissue patterning across diverse cell types. Here, we show that spontaneous calcium waves arise among non-neuronal support cells in the developing Drosophil...
www.science.org
November 21, 2025 at 12:56 PM
Well deserved, Ben! 🎉
Reposted by Neha Ghosh
Congrats Ben, Claude, et al! A beautiful characterization of roles of Ca++ waves and gap junction functions in tissue patterning!
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Retinal calcium waves coordinate uniform tissue patterning of the Drosophila eye
Optimal neural processing relies on precise tissue patterning across diverse cell types. Here, we show that spontaneous calcium waves arise among non-neuronal support cells in the developing Drosophil...
www.science.org
November 21, 2025 at 11:02 AM
Congrats Ben, Claude, et al! A beautiful characterization of roles of Ca++ waves and gap junction functions in tissue patterning!
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Neha Ghosh
Attempt number seven at uploading this video of intermediate filaments in an enormous COS7 cell. I have a feeling the BlueSky compression will not do it any favors.
November 21, 2025 at 3:54 AM
Attempt number seven at uploading this video of intermediate filaments in an enormous COS7 cell. I have a feeling the BlueSky compression will not do it any favors.
Reposted by Neha Ghosh
I am very excited to be organizing a session for postdocs (with focus on those in the job market). Be on the lookout for info and registration! 🐟🧪
November 19, 2025 at 7:12 PM
I am very excited to be organizing a session for postdocs (with focus on those in the job market). Be on the lookout for info and registration! 🐟🧪
Reposted by Neha Ghosh
SAVE THE DATE! Stoked to organize the 2026 Santa Cruz Developmental Biology Meeting with @rashmi-priya.bsky.social, @lowelab.bsky.social, and Shelbi Russell. Come learn about Biomedicine, Biomechanics, and the Biosphere, August 24-28, 2026. Registration dates, etc., coming soon! Please RT
November 19, 2025 at 8:23 PM
SAVE THE DATE! Stoked to organize the 2026 Santa Cruz Developmental Biology Meeting with @rashmi-priya.bsky.social, @lowelab.bsky.social, and Shelbi Russell. Come learn about Biomedicine, Biomechanics, and the Biosphere, August 24-28, 2026. Registration dates, etc., coming soon! Please RT
Reposted by Neha Ghosh
#aECM Cub starts next week Nov 18 with talks on patterning the Drosophila lens, mouse tectorial membrane, and C.elegans cuticle furrows. You can still sign up for access using the link below.
The 2025-2026 #aECM club schedule is now posted on our website, where you can also find the link to sign up for access. I’m looking forward to lots of great talks and discussions! sundaramlab.com/blog/aecm-cl...
aECM Club Seminars
A virtual seminar series to highlight work on apical ECM across different systems Organizers: Meera Sundaram, UPennMax Heiman, Boston Children’s, Harvard U.Nathalie Pujol, U. Aix MarseilleJor…
sundaramlab.com
November 14, 2025 at 11:56 AM
#aECM Cub starts next week Nov 18 with talks on patterning the Drosophila lens, mouse tectorial membrane, and C.elegans cuticle furrows. You can still sign up for access using the link below.
Reposted by Neha Ghosh
How do four-eyed fish see above & underwater? 🌤️🌊 Our new preprint reveals how Anableps rewired its retina for dual vision- evolution at work 👁️👁️ Kudos to @perezlouise.bsky.social @josanesousa.bsky.social @keylapruett.bsky.social + team!
🔗 tinyurl.com/3a8r9xy5
🔗 tinyurl.com/3a8r9xy5
November 4, 2025 at 3:56 PM
How do four-eyed fish see above & underwater? 🌤️🌊 Our new preprint reveals how Anableps rewired its retina for dual vision- evolution at work 👁️👁️ Kudos to @perezlouise.bsky.social @josanesousa.bsky.social @keylapruett.bsky.social + team!
🔗 tinyurl.com/3a8r9xy5
🔗 tinyurl.com/3a8r9xy5
Reposted by Neha Ghosh
Development that lasts a life time. Check out the 2025 special issue of @dev-journal.bsky.social on Lifelong Development: the Maintenance, Regeneration and Plasticity of Tissues
journals.biologists.com/dev/issue/15...
journals.biologists.com/dev/issue/15...
Volume 152 Issue 20 | Development | The Company of Biologists
journals.biologists.com
November 5, 2025 at 8:54 AM
Development that lasts a life time. Check out the 2025 special issue of @dev-journal.bsky.social on Lifelong Development: the Maintenance, Regeneration and Plasticity of Tissues
journals.biologists.com/dev/issue/15...
journals.biologists.com/dev/issue/15...
Reposted by Neha Ghosh
Required reading for cell biologists to get a sense of basic statistical principles!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Ten essential tips for robust statistics in cell biology - Nature Cell Biology
Statistical thinking is a core part of solid, trustworthy biology. However, many studies still include insufficient sample sizes, have poor experimental design or select an incorrect statistical metho...
www.nature.com
November 4, 2025 at 7:23 PM
Required reading for cell biologists to get a sense of basic statistical principles!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Neha Ghosh
Vinculin is a simple adapter protein right? Wrong!
That’s been the prevailing view for the 46 years since it was discovered.
Here we provide a new paradigm and show that vinculin is a complex mechanosensor itself, containing 6 binary switch domains.
www.science.org/doi/10.1126/...
That’s been the prevailing view for the 46 years since it was discovered.
Here we provide a new paradigm and show that vinculin is a complex mechanosensor itself, containing 6 binary switch domains.
www.science.org/doi/10.1126/...
The mechanical response of vinculin
Vinculin buffers force via dynamic domain unfolding/refolding under physiological load and lacks a stable head-tail lock.
www.science.org
October 31, 2025 at 6:29 PM
Vinculin is a simple adapter protein right? Wrong!
That’s been the prevailing view for the 46 years since it was discovered.
Here we provide a new paradigm and show that vinculin is a complex mechanosensor itself, containing 6 binary switch domains.
www.science.org/doi/10.1126/...
That’s been the prevailing view for the 46 years since it was discovered.
Here we provide a new paradigm and show that vinculin is a complex mechanosensor itself, containing 6 binary switch domains.
www.science.org/doi/10.1126/...
An absolute stunner!
Can't believe it — my first‑author paper is out and my image graces the cover of @dev-journal.bsky.social 🎉
Here, we reveal how early developmental programs shape and maintain #zebrafish gill architecture throughout life
🔗 journals.biologists.com/dev/issue/15...
#FluorescenceFriday #LifelongDevSI
Here, we reveal how early developmental programs shape and maintain #zebrafish gill architecture throughout life
🔗 journals.biologists.com/dev/issue/15...
#FluorescenceFriday #LifelongDevSI
November 1, 2025 at 12:13 AM
An absolute stunner!
Reposted by Neha Ghosh
Excited to announce the final version of the Mosquito Cell Atlas is out now in @cellpress.bsky.social!! 🦟🩸
There is SO much left to find & investigate in this dataset (& the rich biology of the Aedes aegypti mosquito)! We hope this helps scientists in many fields!
www.cell.com/cell/fulltex...
There is SO much left to find & investigate in this dataset (& the rich biology of the Aedes aegypti mosquito)! We hope this helps scientists in many fields!
www.cell.com/cell/fulltex...
A single-nucleus transcriptomic atlas of the adult Aedes aegypti mosquito
A comprehensive single-nucleus RNA-seq atlas of >367,000 nuclei from male and female
Aedes aegypti mosquitoes reveals sexual dimorphism in sensory systems and brain cell
types and widespread co-expres...
www.cell.com
October 30, 2025 at 4:05 PM
Excited to announce the final version of the Mosquito Cell Atlas is out now in @cellpress.bsky.social!! 🦟🩸
There is SO much left to find & investigate in this dataset (& the rich biology of the Aedes aegypti mosquito)! We hope this helps scientists in many fields!
www.cell.com/cell/fulltex...
There is SO much left to find & investigate in this dataset (& the rich biology of the Aedes aegypti mosquito)! We hope this helps scientists in many fields!
www.cell.com/cell/fulltex...
Reposted by Neha Ghosh
The ECM is no longer in the back seat when it comes to development. Check out our special issue "Dynamics of the extracellular matrix in development, cell physiology and disease" with 8 selected articles to learn more: A 🧵 www.sciencedirect.com/special-issu...
Cells & Development | Dynamics of the extracellular matrix in development, cell physiology and disease. | ScienceDirect.com by Elsevier
Extracellular matrices (ECMs) are everywhere in our body– from the sheet-like basement membranes that line epithelia and other tissues - to the loose stromal arrays of mesenchyme - to the rigid struct...
www.sciencedirect.com
October 30, 2025 at 5:48 PM
The ECM is no longer in the back seat when it comes to development. Check out our special issue "Dynamics of the extracellular matrix in development, cell physiology and disease" with 8 selected articles to learn more: A 🧵 www.sciencedirect.com/special-issu...
Reposted by Neha Ghosh
Ascidians (Ciona intestinalis)🪸Our distant chordate cousins! 🌊 Simple sea squirts that reveal how vertebrate body plans evolved 🧬 A key model for notochord formation, neural induction, and cell lineage mapping 📸 Video by MBL Embryology 2019 #ModelMonday #DevBio #EvoDevo
October 28, 2025 at 12:46 AM
Ascidians (Ciona intestinalis)🪸Our distant chordate cousins! 🌊 Simple sea squirts that reveal how vertebrate body plans evolved 🧬 A key model for notochord formation, neural induction, and cell lineage mapping 📸 Video by MBL Embryology 2019 #ModelMonday #DevBio #EvoDevo