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Reposted by Madhvi Menon

Marion Pepper @marionpepper.bsky.social · 2d

Asthma is a chronic disease characterized by acute, intermittent, recurrent episodes of airway inflammation. A decade of work developing the tools, techniques and collaborations needed to figure out how CD4+ T cells in the lungs propagate disease can be found here:
www.biorxiv.org/content/10.1...

Tertiary lymphoid structures support the development of allergen-specific progenitor CD4+ T cells

Tissue-resident memory CD4+ T cells (TRM) are key sentinels of the adaptive immune response that provide a rapid, robust inflammatory response upon reactivation in non-lymphoid tissues. While CD4+ TRM...

www.biorxiv.org

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Reposted by Madhvi Menon

Dr Emma S Chambers @emmaschambers.bsky.social · 3d

I am so proud to say that our paper is now available at Aging Cell. There is a paucity of data as to how the menopause impacts your immune system, and the aim of this study was to investigate the impact of the menopause on monocyte phenotype and function.
onlinelibrary.wiley.com/doi/10.1111/...

Age‐Associated Inflammatory Monocytes Are Increased in Menopausal Females and Reversed by Hormone Replacement Therapy

Post-menopausal females (> 64 years) have an increase in frequency of inflammatory monocyte populations with defective phagocytosis as compared to pre-menopausal (< 40 years) females. Hormone Replace....

onlinelibrary.wiley.com

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Reposted by Madhvi Menon

Adrian Liston @labliston.bsky.social · 23d

For our #flowcytometry peeps, would you like to have a single fix/perm protocol that is optimised for everything? One that preserves fluorophores while allowing simultaneous TF and cytokine staining? How about 100-fold cheaper?

You got it:
currentprotocols.onlinelibrary.wiley.com/doi/10.1002/...

currentprotocols.onlinelibrary.wiley.com

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Doug Dyer @douglaspdyer.bsky.social · 20d

We now have a very exciting technician post advertised as part of our long term Wellcome Trust funded team investigating the role of the glycocalyx during CNS inflammation. Supporint the lab, developing glycan analysis and research experience www.jobs.manchester.ac.uk/Job/JobDetai...

Research Technician in the Glyco-immunology (Dyer) Lab:Oxford Road

Include: background, duties, essential skills and experience, length of contract, full or part-time. Keep to 150 words.

www.jobs.manchester.ac.uk

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Lydia Becker Institute @lydiabeckeriii.bsky.social · 5d

This year's Nobel Prize in Medicine honors the discovery of regulatory T cells (T-regs).

In this piece, our Director Prof Tracy Hussell @tracyh9494.bsky.social explains how the recipients discovered T-regs - transforming autoimmune disease research.

#ImmunoSky

theconversation.com/nobel-prize-...

Nobel prize awarded for discovery of immune system’s ‘security guards’

The discovery of cells that prevent the immune system from hurting the body is paving the way for new treatments for autoimmune diseases and cancer.

theconversation.com

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Tara Sutherland @drtesutherland.bsky.social · 20d

Extremely happy to see our work out in #ScienceImmunology. We show allergen-induced ECM remodelling occurs independently of IL-13 or IL-17 driven inflammation. Rather chitinase-like proteins drive airway ECM accumulation & inhibition of Ym1 can remarkably reverse it. www.science.org/doi/10.1126/...

Allergen-induced airway matrix remodeling in mice can be prevented or reversed by targeting chitinase-like proteins

Allergic airway matrix remodeling occurs independently of IL-13 and IL-17A and is driven instead by chitinase-like proteins.

www.science.org

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Doug Dyer @douglaspdyer.bsky.social · Sep 12

We have a new Postdoc position advertised as part of our recent long-term Wellcome funding to join an established Postdoc and technician. I’m so excited to explore the role of the glycocalyx in CNS-inflammation. So many tools and expertise to work with! www.jobs.manchester.ac.uk/Job/JobDetai...

Research Associate in in Neuro-Immunology and Extraceullar Matrix Biology (ImmunoMatrix):Oxford Road

Our Glyco-Immunology (Dyer) lab has produced published and preliminary data demonstrating that an under-appreciated structure, the glycocalyx, on endothelial- and immune- cells regulates immune cell recruitment by:

www.jobs.manchester.ac.uk

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Reposted by Madhvi Menon

Adrian Liston @labliston.bsky.social · Sep 3

🧵How to write and manage your first research budgets

The point of funding is to convert it into quality research. A well-spent research budget should fund the idea it was raised on, plus revision experiments, plus preliminary data for the next grant. So you need to spend, while avoiding waste.

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Madhvi Menon @madhvimenon.bsky.social · 27d

🔔 Fantastic opportunities to join us as part of the new and exciting @exposomeimmunology.bsky.social
@lydiabeckeriii.bsky.social

Check out the details 👇

Please spread the word! #immunosky

MRC CoRE in Exposome Immunology @exposomeimmunology.bsky.social · Sep 8

WE ARE HIRING! www.manchester.ac.uk/exposome-jobs

Vacancies inc. 3x PDRA positions, 2x data scientists and a Transition Fellowship in Air Pollution.

Join us as we embark on a 14 year journey to understand how the exposome impacts immune regulation and chronic inflammation.

#hiring #immunosky

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MRC CoRE in Exposome Immunology @exposomeimmunology.bsky.social · Sep 9

🎓 6x fully-funded 4-year PhD studentships 🎓

We are recruiting our first cohort of PhD students to start Oct 2026.

Students will shape their own projects within supervisory teams spanning the universities of Manchester & Oxford.

www.findaphd.com/phds/program/mrc-core-in-exposome-immunology/?p6899

FindAPhD : MRC CoRE in Exposome Immunology at The University of Manchester

Apply for a PhD: MRC CoRE in Exposome Immunology at The University of Manchester

www.findaphd.com

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Reposted by Madhvi Menon

Rebecca Drummond 🍄 @therad-lab.bsky.social · Aug 18

There's one week left to apply for postdoc positions in my group. Links to apply below!
#academicjobs #researchjobs #immunosky

Rebecca Drummond 🍄 @therad-lab.bsky.social · Jul 30

Job ads for TWO postdoctoral positions available in our group are now online. Deadline August 25th.
🧪Immunologists, apply in link below.
🍄Microbiologists- please follow link in next post.
edzz.fa.em3.oraclecloud.com/hcmUI/Candid...

Research Fellow - Department of Immunology and Immunotherapy - 106119 - Grade 7

The successful candidate will make extensive use of a range of in vivo models of fungal infection and will have access to the wide range of transgenic tools and in vivo immunology techniques establish...

edzz.fa.em3.oraclecloud.com

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tovah-shaw-lab.bsky.social @tovah-shaw-lab.bsky.social · Aug 12

I am recruiting for a postdoc that wants to work on an exciting project on gut macrophages, TGFb signalling, and colon cancer! Please see the link for details - elxw.fa.em3.oraclecloud.com/hcmUI/Candid...

Postdoctoral Research Associate

We are looking for a talented and enthusiastic postdoctoral researcher to join the Shaw lab to investigate identify the regulatory function of NRROS/LRRC33 in gastrointestinal macrophage development a...

elxw.fa.em3.oraclecloud.com

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Reposted by Madhvi Menon

Maria Polychronidou @mpolychronidou.bsky.social · Jul 23

Dental floss as a #vaccination strategy? This study shows that floss-based vaccination can deliver protein, inactivated virus, peptide-presenting immunogenic nanoparticles, mRNA & induces #immuneresponses protecting against infectious disease in mice ➡️ www.nature.com/articles/s41... #immunity

Floss-based vaccination targets the gingival sulcus for mucosal and systemic immunization - Nature Biomedical Engineering

Floss-based vaccination exploits the leaky junctional epithelium of the gingival sulcus to deliver different types of vaccine, inducing robust mucosal and systemic immunity and providing protection ag...

www.nature.com

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Matthew Sinton 🏳️‍🌈 @mcsinton.bsky.social · Jul 25

So excited to go to the IUIS and present our work on adipose tissue and systemic immunometabolism!

International Union of Immunological Societies @iuis-online.bsky.social · Jul 23

Meet @mcsinton.bsky.social, immunometabolism researcher & Wellcome Fellow @ Manchester. He’ll present “Fat on the frontline: fuelling immunity in chronic infection.” https://loom.ly/CwagY2g #Immunosky @lydiabeckeriii.bsky.social

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The Lister Institute of Preventive Medicine @thelisterinstitute.bsky.social · Jul 22

#ListerFellow Lizzy Rosser's research into juvenile idiopathic arthritis (JIA) and uveitis is driven by curiosity—and shaped by the voices of young patients and their families.

🧠 Comment how connection with patients and their families makes a difference 👇

📖 lister-institute.org.uk/the-bigger-p...

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Lydia Becker Institute @lydiabeckeriii.bsky.social · Jul 16

🚨 A new £50M MRC Centre at @manchester.ac.uk and @ox.ac.uk will explore how pollution, microbes & other environmental exposures rewire our immune system and cause chronic inflammatory diseases.
#Exposome #ImmunoSky

sites.manchester.ac.uk/lydia-becker...

New £50m MRC Centre to study how environmental exposures cause chronic inflammatory diseases

A groundbreaking £50M research centre at Manchester and Oxford will explore how environmental exposures, like pollution and microbes, rewire our immune system and drive chronic inflammatory diseases.

sites.manchester.ac.uk

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Prof Sheena Cruickshank @sheencr.bsky.social · Jul 16

So excited to FINALLY be able to share exciting news from @lydiabeckeriii.bsky.social on our newly awarded MRC Centre of Research Excellence (MRC CoRE) in Exposome Immunology #ImmunoSky 🧪 🧵

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Reposted by Madhvi Menon

Judi Allen @profjudiallen.bsky.social · Jul 16

Super excited to announce that MRC has funded a new Centre of Research Excellence in Exposome Immunology. Working together, Manchester and Oxford are going to tackle a major challenge of our times. For those who wonder what the Exposome is - see yesterday's posts! www.ukri.org/news/centre-...

Centre to study how exposome causes chronic inflammatory disease

A new Medical Research Council (MRC) centre will investigate how the environment interacts with our immune system to trigger chronic inflammatory diseases.

www.ukri.org

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Reposted by Madhvi Menon

yEFIS @yefis-immunology.bsky.social · Jul 4

🚨 Postdoctoral Opportunity – B cells & Chronic Lung Disease

The Menon Lab @madhvimenon.bsky.social at The University of Manchester is recruiting!

🔗 More info & to apply:
www.jobs.manchester.ac.uk/Job/JobDetai...

📅 Deadline: 7 July

Read more 👇👇👇

Research Associate in Mucosal Immunology :Manchester

www.jobs.manchester.ac.uk

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Madhvi Menon @madhvimenon.bsky.social · Jul 1

Thanks for sharing! 💛

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Pallett Lab UCL @pallettlab.bsky.social · Jul 1

The fantastic Menon Lab (@madhvimenon.bsky.social) in the @lydiabeckeriii.bsky.social in Manchester are hiring!!
🚨DO NOT MISS YOUR CHANCE TO APPLY!🚨

www.jobs.manchester.ac.uk/Job/JobDetai...

Postdoc seeking to unravel how lung-infiltrating #Bcells contribute to chronic lung disease #immunosky

Research Associate in Mucosal Immunology :Manchester

www.jobs.manchester.ac.uk

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Prof Sheena Cruickshank @sheencr.bsky.social · Jun 29

Damming report by RCGP on air pollution and risks to health occurs alongside a worrying escalation in asthma presentations to family doctors in England in the first 6 months with 45,458 versus 31,376 cases the same time last yr.

Calls to clean up England’s ‘toxic air’ as GP visits for asthma attacks rise 45%

Exclusive: Doctors say clean air zones need expanding, after 45,458 visits in first half of this year – up from 31,376 last year

www.theguardian.com

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Fran Quintana Lab @quintanalabhms.bsky.social · Jun 25

Our newest paper studying immunosuppressive astrocyte-GBM interactions using RABID-seq is out in ‪@nature.com today! Congrats to Brian Andersen and Camilo Faust Akl!
www.nature.com/articles/s41...

Barcoded viral tracing identifies immunosuppressive astrocyte–glioma interactions - Nature

Using viral barcode tracing to detect interactions between glioblastoma cells and non-malignant astrocytes in patient samples, investigators discovered a pathway that reduces tumour-specific immunity ...

www.nature.com

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Madhvi Menon @madhvimenon.bsky.social · Jun 20

🚨 The Menon lab is hiring a postdoc!

Interested in mucosal immunology? Come join our team to study lung-infiltrating B cell dynamics in COPD & other chronic lung diseases
@ukri.org @lydiabeckeriii.bsky.social

Please help spread the word #ImmunoSky

www.jobs.manchester.ac.uk/Job/JobDetai...

Research Associate in Mucosal Immunology :Manchester

www.jobs.manchester.ac.uk

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Madhvi Menon @madhvimenon.bsky.social · Jun 20

🚨 The Menon lab is hiring a postdoc!

Interested in mucosal immunology? Come join our team to study lung-infiltrating B cell dynamics in COPD & other chronic lung diseases
@ukri.org @lydiabeckeriii.bsky.social

Please help spread the word #ImmunoSky

www.jobs.manchester.ac.uk/Job/JobDetai...

Research Associate in Mucosal Immunology :Manchester

www.jobs.manchester.ac.uk

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