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Reposted by MRC CoRE in Exposome Immunology

Lydia Becker Institute @lydiabeckeriii.bsky.social · 6d

This year's Nobel Prize in Medicine honors the discovery of regulatory T cells (T-regs).

In this piece, our Director Prof Tracy Hussell @tracyh9494.bsky.social explains how the recipients discovered T-regs - transforming autoimmune disease research.

#ImmunoSky

theconversation.com/nobel-prize-...

Nobel prize awarded for discovery of immune system’s ‘security guards’

The discovery of cells that prevent the immune system from hurting the body is paving the way for new treatments for autoimmune diseases and cancer.

theconversation.com

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Reposted by MRC CoRE in Exposome Immunology

Yang Luo @y-luo.bsky.social · 11d

🌟 Postdoc Opportunity – MRC CoRE in Exposome Immunology 🌟
Join us to explore how the exposome shapes complex disease risk using multi-omics & global biobank data. @kiroxford.bsky.social , @exposomeimmunology.bsky.social

✅ Apply: lnkd.in/gJHJDvKn

🗓️ Deadline: 12pm, 30 Oct 2025

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Reposted by MRC CoRE in Exposome Immunology

Becky Dodd @becky-dodd.bsky.social · 23d

Allergen-induced airway matrix remodeling in mice can be prevented or reversed by targeting chitinase-like proteins | Science Immunology www.science.org/doi/10.1126/... 🎉🎉
@hetompkins.bsky.social @drtesutherland.bsky.social @mattoburgess.bsky.social @james-ep.bsky.social
@profjudiallen.bsky.social

Allergen-induced airway matrix remodeling in mice can be prevented or reversed by targeting chitinase-like proteins

Allergic airway matrix remodeling occurs independently of IL-13 and IL-17A and is driven instead by chitinase-like proteins.

www.science.org

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Reposted by MRC CoRE in Exposome Immunology

David Posner, PhD @davidposner.bsky.social · 27d

New paper alert! 🎉 Check it out here: biorxiv.org/content/10.1... Here we show that intestinal bacterial, helminth and fungal challenges polarise CD4 T cell populations in the dural meninges.

Intestinal challenges shape the polarisation of protective dural memory CD4 T cells

The meninges house several innate and adaptive immune cell populations[1][1]–[3][2]. These predominantly localise within the dura mater and include gut-derived IgA-secreting plasma cells[4][3]. Whethe...

biorxiv.org

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Reposted by MRC CoRE in Exposome Immunology

Doug Dyer @douglaspdyer.bsky.social · Sep 12

We have a new Postdoc position advertised as part of our recent long-term Wellcome funding to join an established Postdoc and technician. I’m so excited to explore the role of the glycocalyx in CNS-inflammation. So many tools and expertise to work with! www.jobs.manchester.ac.uk/Job/JobDetai...

Research Associate in in Neuro-Immunology and Extraceullar Matrix Biology (ImmunoMatrix):Oxford Road

Our Glyco-Immunology (Dyer) lab has produced published and preliminary data demonstrating that an under-appreciated structure, the glycocalyx, on endothelial- and immune- cells regulates immune cell recruitment by:

www.jobs.manchester.ac.uk

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MRC CoRE in Exposome Immunology @exposomeimmunology.bsky.social · Sep 10

Standing room only for the entertaining and touching inaugural lectures of Prof Matt Hepworth and Prof Cath Lawrence today, featuring surprise cameos from Rasputin, an angry goose, and a fondly remembered comic book character.

Congratulations! 🥳

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MRC CoRE in Exposome Immunology @exposomeimmunology.bsky.social · Sep 9

🎓 6x fully-funded 4-year PhD studentships 🎓

We are recruiting our first cohort of PhD students to start Oct 2026.

Students will shape their own projects within supervisory teams spanning the universities of Manchester & Oxford.

www.findaphd.com/phds/program/mrc-core-in-exposome-immunology/?p6899

FindAPhD : MRC CoRE in Exposome Immunology at The University of Manchester

Apply for a PhD: MRC CoRE in Exposome Immunology at The University of Manchester

www.findaphd.com

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MRC CoRE in Exposome Immunology @exposomeimmunology.bsky.social · Sep 8

WE ARE HIRING! www.manchester.ac.uk/exposome-jobs

Vacancies inc. 3x PDRA positions, 2x data scientists and a Transition Fellowship in Air Pollution.

Join us as we embark on a 14 year journey to understand how the exposome impacts immune regulation and chronic inflammation.

#hiring #immunosky

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