Leon-Samuel Icking
@lsi.bsky.social
PhD student from the Kalmbach Lab in Neuchâtel
flowerpunk 🏵️ + solarpunk ☀
Anything SynBio (and Plants 👀)!
iGEM Freiburg Ultra🤘
Chaotic neutral
flowerpunk 🏵️ + solarpunk ☀
Anything SynBio (and Plants 👀)!
iGEM Freiburg Ultra🤘
Chaotic neutral
Pinned
If iGEM Freiburg has 100 fans, I'm one of them.
If they have 10 fans, I'm one of them.
If they have one fan, I'm that fan.
If they have 0 fans, I'm dead.
@biologyunifreiburg.bsky.social @cibss.bsky.social
If they have 10 fans, I'm one of them.
If they have one fan, I'm that fan.
If they have 0 fans, I'm dead.
@biologyunifreiburg.bsky.social @cibss.bsky.social
Reposted by Leon-Samuel Icking
You are embarrassing yourself by lauding this monster. Do you defend these views, which he held lifelong. Where is the "nuance in these words?" Shame!
liorpachter.wordpress.com/2018/05/18/j...
liorpachter.wordpress.com/2018/05/18/j...
November 8, 2025 at 12:37 PM
You are embarrassing yourself by lauding this monster. Do you defend these views, which he held lifelong. Where is the "nuance in these words?" Shame!
liorpachter.wordpress.com/2018/05/18/j...
liorpachter.wordpress.com/2018/05/18/j...
Reposted by Leon-Samuel Icking
Plant Science Research Weekly -- Illuminating plant immunity: a live sensor to watch salicylic acid in action (Science) @bijuntang.bsky.social @xanderjones.bsky.social @botanicaljim.bsky.social @philcarella.bsky.social (Summary by Ching Chan) buff.ly/SF8nZ9R
#PlantaePSRW
#PlantaePSRW
Illuminating plant immunity: A live sensor to watch salicylic acid in action | Plantae
Salicylic acid (SA) is best known as a central hormone orchestrating plant immune response, including the hypersensitive reaction and systemic acquired resistance. Beyond defense…
buff.ly
November 7, 2025 at 9:15 PM
Plant Science Research Weekly -- Illuminating plant immunity: a live sensor to watch salicylic acid in action (Science) @bijuntang.bsky.social @xanderjones.bsky.social @botanicaljim.bsky.social @philcarella.bsky.social (Summary by Ching Chan) buff.ly/SF8nZ9R
#PlantaePSRW
#PlantaePSRW
Reposted by Leon-Samuel Icking
Sub-cellular chemical mapping in bacteria using correlated cryogenic electron and mass spectrometry imaging
Congrats Hannah Ochner and authors on this important paper! Strong collaboration with @kiranrpatil.bsky.social
www.biorxiv.org/cgi/content/...
@mrclmb.bsky.social @wellcometrust.bsky.social
Congrats Hannah Ochner and authors on this important paper! Strong collaboration with @kiranrpatil.bsky.social
www.biorxiv.org/cgi/content/...
@mrclmb.bsky.social @wellcometrust.bsky.social
August 31, 2025 at 6:44 PM
Sub-cellular chemical mapping in bacteria using correlated cryogenic electron and mass spectrometry imaging
Congrats Hannah Ochner and authors on this important paper! Strong collaboration with @kiranrpatil.bsky.social
www.biorxiv.org/cgi/content/...
@mrclmb.bsky.social @wellcometrust.bsky.social
Congrats Hannah Ochner and authors on this important paper! Strong collaboration with @kiranrpatil.bsky.social
www.biorxiv.org/cgi/content/...
@mrclmb.bsky.social @wellcometrust.bsky.social
Congratz to @reneinckemann.bsky.social and team! Long time in the oven!
New OA Article: "A modular high-throughput approach for advancing synthetic biology in the chloroplast of Chlamydomonas" rdcu.be/eOdZP
Modular-cloning-based platform for high-throughput chloroplast engineering in Chlamydomonas reinhardtii.
Modular-cloning-based platform for high-throughput chloroplast engineering in Chlamydomonas reinhardtii.
November 6, 2025 at 9:54 PM
Congratz to @reneinckemann.bsky.social and team! Long time in the oven!
Reposted by Leon-Samuel Icking
Arabidopsis, a little weed in the mustard family, joined the celebrity ranks of Drosophila, E. coli and other model organisms in the 1980s. There was a lot of pushback-- in some circles it was referred to as the "A-word" (!)
Arabidopsis thaliana was always an unlikely candidate for the limelight. But 25 years ago, the diminutive thale cress launched the botanical world into the molecular era.
✍️ Rachel Ehrenberg
knowmag.org/4hImL8e
✍️ Rachel Ehrenberg
knowmag.org/4hImL8e
How a humble weed became a superstar of biology
Arabidopsis thaliana was always an unlikely candidate for the limelight. But 25 years ago, the diminutive thale cress launched the botanical world into the molecular era.
knowmag.org
November 4, 2025 at 4:00 PM
Arabidopsis, a little weed in the mustard family, joined the celebrity ranks of Drosophila, E. coli and other model organisms in the 1980s. There was a lot of pushback-- in some circles it was referred to as the "A-word" (!)
1 done - 23 to go
November 4, 2025 at 12:05 PM
1 done - 23 to go
Reposted by Leon-Samuel Icking
My new Emmy Noether Group is recruiting!
🔬 Two PhD positions in plant pathogen evolution
🧬 Start: April 2026 (flexible)
📍 Dept. of Phytopathology & Plant Protection @rstam.bsky.social @uni-kiel.de
⏰ Apply by 15 Dec 2025
🔗 More info: www.uni-kiel.de/personal/de/...
Do get in touch or share 😊
🔬 Two PhD positions in plant pathogen evolution
🧬 Start: April 2026 (flexible)
📍 Dept. of Phytopathology & Plant Protection @rstam.bsky.social @uni-kiel.de
⏰ Apply by 15 Dec 2025
🔗 More info: www.uni-kiel.de/personal/de/...
Do get in touch or share 😊
Aktuelle Ausschreibungen
Aktuelle Ausschreibungen
www.uni-kiel.de
November 3, 2025 at 9:03 AM
My new Emmy Noether Group is recruiting!
🔬 Two PhD positions in plant pathogen evolution
🧬 Start: April 2026 (flexible)
📍 Dept. of Phytopathology & Plant Protection @rstam.bsky.social @uni-kiel.de
⏰ Apply by 15 Dec 2025
🔗 More info: www.uni-kiel.de/personal/de/...
Do get in touch or share 😊
🔬 Two PhD positions in plant pathogen evolution
🧬 Start: April 2026 (flexible)
📍 Dept. of Phytopathology & Plant Protection @rstam.bsky.social @uni-kiel.de
⏰ Apply by 15 Dec 2025
🔗 More info: www.uni-kiel.de/personal/de/...
Do get in touch or share 😊
Reposted by Leon-Samuel Icking
So proud of our UNILausanne iGEM team! 🏆🥇 Best Entrepreneurship, placed in the Top 10 Overgrad teams, won a Gold Medal, and were nominated for Best Education, Best Wiki, and Best Biomanufacturing Project. Incredible achievement! #iGEM
@fbm-unil.bsky.social @unil.bsky.social
@fbm-unil.bsky.social @unil.bsky.social
November 3, 2025 at 10:10 AM
So proud of our UNILausanne iGEM team! 🏆🥇 Best Entrepreneurship, placed in the Top 10 Overgrad teams, won a Gold Medal, and were nominated for Best Education, Best Wiki, and Best Biomanufacturing Project. Incredible achievement! #iGEM
@fbm-unil.bsky.social @unil.bsky.social
@fbm-unil.bsky.social @unil.bsky.social
Reposted by Leon-Samuel Icking
Thrilled to share that this work has been accepted for publication @currentbiology.bsky.social 🥳
Special shoutout to the editorial team – the process was incredibly smooth and productive. Read more here:
www.sciencedirect.com/science/arti...
Special shoutout to the editorial team – the process was incredibly smooth and productive. Read more here:
www.sciencedirect.com/science/arti...
November 3, 2025 at 3:56 AM
Thrilled to share that this work has been accepted for publication @currentbiology.bsky.social 🥳
Special shoutout to the editorial team – the process was incredibly smooth and productive. Read more here:
www.sciencedirect.com/science/arti...
Special shoutout to the editorial team – the process was incredibly smooth and productive. Read more here:
www.sciencedirect.com/science/arti...
Reposted by Leon-Samuel Icking
A wheat NLR conferring broad-spectrum resistance against powdery mildew by recognizing two structurally diverse AVR effectors. Interested? Check out our newest preprint: www.biorxiv.org/content/10.1...
Dual recognition of structurally unrelated mildew effectors underlies the broad-spectrum resistance of Pm3e in wheat
Broad-spectrum resistance genes are highly valuable for sustainable crop protection, yet the molecular basis of their activity is often unknown. The Pm3 allelic series in wheat encodes NLR receptors t...
www.biorxiv.org
November 2, 2025 at 1:29 PM
A wheat NLR conferring broad-spectrum resistance against powdery mildew by recognizing two structurally diverse AVR effectors. Interested? Check out our newest preprint: www.biorxiv.org/content/10.1...
Reposted by Leon-Samuel Icking
arXiv will no longer accept review articles and position papers unless they have been accepted at a journal or a conference and complete successful peer review.
This is due to being overwhelmed by a hundreds of AI generated papers a month.
Yet another open submission process killed by LLMs.
This is due to being overwhelmed by a hundreds of AI generated papers a month.
Yet another open submission process killed by LLMs.
Attention Authors: Updated Practice for Review Articles and Position Papers in arXiv CS Category – arXiv blog
blog.arxiv.org
November 1, 2025 at 5:28 PM
arXiv will no longer accept review articles and position papers unless they have been accepted at a journal or a conference and complete successful peer review.
This is due to being overwhelmed by a hundreds of AI generated papers a month.
Yet another open submission process killed by LLMs.
This is due to being overwhelmed by a hundreds of AI generated papers a month.
Yet another open submission process killed by LLMs.
Discussing plant science with a plant scientist and an immunologist. Guess who's who!
November 1, 2025 at 7:44 PM
Discussing plant science with a plant scientist and an immunologist. Guess who's who!
If iGEM Freiburg has 100 fans, I'm one of them.
If they have 10 fans, I'm one of them.
If they have one fan, I'm that fan.
If they have 0 fans, I'm dead.
@biologyunifreiburg.bsky.social @cibss.bsky.social
If they have 10 fans, I'm one of them.
If they have one fan, I'm that fan.
If they have 0 fans, I'm dead.
@biologyunifreiburg.bsky.social @cibss.bsky.social
November 1, 2025 at 9:10 AM
If iGEM Freiburg has 100 fans, I'm one of them.
If they have 10 fans, I'm one of them.
If they have one fan, I'm that fan.
If they have 0 fans, I'm dead.
@biologyunifreiburg.bsky.social @cibss.bsky.social
If they have 10 fans, I'm one of them.
If they have one fan, I'm that fan.
If they have 0 fans, I'm dead.
@biologyunifreiburg.bsky.social @cibss.bsky.social
October 31, 2025 at 7:38 PM
October 31, 2025 at 5:06 PM
Already wrapping up this week but now up for the most exciting stuff! So sad I couldn't talk about the teams yet as a judge but will do a follow up with trends I have seen
October 31, 2025 at 3:57 PM
Already wrapping up this week but now up for the most exciting stuff! So sad I couldn't talk about the teams yet as a judge but will do a follow up with trends I have seen
Reposted by Leon-Samuel Icking
CREation of an expanded plant memory gene circuit toolkit https://www.biorxiv.org/content/10.1101/2025.10.28.684748v1
October 29, 2025 at 2:04 AM
CREation of an expanded plant memory gene circuit toolkit https://www.biorxiv.org/content/10.1101/2025.10.28.684748v1
Reposted by Leon-Samuel Icking
Great commentary by
@yulonglilab
on our two recent papers introducing red genetically encoded biosensors for calcium and potassium imaging!
🔴 FRCaMPi - Enhanced red calcium sensor 🔴 RGEPOs - First-ever red potassium sensors
📖 doi.org/10.1371/jour...
@yulonglilab
on our two recent papers introducing red genetically encoded biosensors for calcium and potassium imaging!
🔴 FRCaMPi - Enhanced red calcium sensor 🔴 RGEPOs - First-ever red potassium sensors
📖 doi.org/10.1371/jour...
Illuminating calcium and potassium dynamics with red fluorescent sensors
Despite recent advances in green genetically encoded ion indicators, developments in red-shifted indicators have been slower. This Primer explores two recent studies in PLOS Biology that engineer red ...
doi.org
October 27, 2025 at 12:58 AM
Great commentary by
@yulonglilab
on our two recent papers introducing red genetically encoded biosensors for calcium and potassium imaging!
🔴 FRCaMPi - Enhanced red calcium sensor 🔴 RGEPOs - First-ever red potassium sensors
📖 doi.org/10.1371/jour...
@yulonglilab
on our two recent papers introducing red genetically encoded biosensors for calcium and potassium imaging!
🔴 FRCaMPi - Enhanced red calcium sensor 🔴 RGEPOs - First-ever red potassium sensors
📖 doi.org/10.1371/jour...
Reposted by Leon-Samuel Icking
Abundant clock proteins point to missing regulation in the plant circadian clock www.embopress.org/doi/full/10.... first experimental determination of the abundance of transcription factors in Plants and for the circadian clock. It was such a challenge but finally out after peer review !!!
Abundant clock proteins point to missing molecular regulation in the plant circadian clock | Molecular Systems Biology
imageimage~100,000 copies of plant circadian clock proteins per cell were predicted from RNA
levels and included in detailed models. Protein levels and DNA-binding were validated,
using NanoLUC report...
www.embopress.org
February 20, 2025 at 5:55 PM
Abundant clock proteins point to missing regulation in the plant circadian clock www.embopress.org/doi/full/10.... first experimental determination of the abundance of transcription factors in Plants and for the circadian clock. It was such a challenge but finally out after peer review !!!
Reposted by Leon-Samuel Icking
Bio product: Crop breeding program that saved a billion lives
Bio rhetoric: “Let’s not overhype this guys”
Tech product: Chatbot that does cyber sex
Tech rhetoric: “Quake before your newborn God”
Bio rhetoric: “Let’s not overhype this guys”
Tech product: Chatbot that does cyber sex
Tech rhetoric: “Quake before your newborn God”
October 17, 2025 at 2:41 PM
Bio product: Crop breeding program that saved a billion lives
Bio rhetoric: “Let’s not overhype this guys”
Tech product: Chatbot that does cyber sex
Tech rhetoric: “Quake before your newborn God”
Bio rhetoric: “Let’s not overhype this guys”
Tech product: Chatbot that does cyber sex
Tech rhetoric: “Quake before your newborn God”
Reposted by Leon-Samuel Icking
I have a PhD position available in my lab at the University of Freiburg!! If you, or someone you know, might be looking for a position using modeling and simulations to uncover secrets in (glyco-)protein structure/function relationships please take a look at our website!
www.kearnslab.org
www.kearnslab.org
October 17, 2025 at 8:21 PM
I have a PhD position available in my lab at the University of Freiburg!! If you, or someone you know, might be looking for a position using modeling and simulations to uncover secrets in (glyco-)protein structure/function relationships please take a look at our website!
www.kearnslab.org
www.kearnslab.org
Reposted by Leon-Samuel Icking
🚨Our paper is out! 🥳
Hijacking a bacterial ABC transporter for efficient genetic code expansion.
Many congrats to everyone involved - a multi-year effort led by @taruniype.bsky.social @maxfottner.bsky.social
www.nature.com/articles/s41...
it all started years ago with a failed experiment
🧵👇 1/9
Hijacking a bacterial ABC transporter for efficient genetic code expansion.
Many congrats to everyone involved - a multi-year effort led by @taruniype.bsky.social @maxfottner.bsky.social
www.nature.com/articles/s41...
it all started years ago with a failed experiment
🧵👇 1/9
Hijacking a bacterial ABC transporter for genetic code expansion - Nature
Bacterial ATP-binding cassette (ABC) transporters can be utilized and engineered to transport non-canonical amino acids into Escherichia coli for highly efficient synthesis of proteins with novel func...
www.nature.com
October 16, 2025 at 2:06 PM
🚨Our paper is out! 🥳
Hijacking a bacterial ABC transporter for efficient genetic code expansion.
Many congrats to everyone involved - a multi-year effort led by @taruniype.bsky.social @maxfottner.bsky.social
www.nature.com/articles/s41...
it all started years ago with a failed experiment
🧵👇 1/9
Hijacking a bacterial ABC transporter for efficient genetic code expansion.
Many congrats to everyone involved - a multi-year effort led by @taruniype.bsky.social @maxfottner.bsky.social
www.nature.com/articles/s41...
it all started years ago with a failed experiment
🧵👇 1/9
Reposted by Leon-Samuel Icking
This week I've been designing constructs and what I found very helpful is the Fluorescent Protein BLAST tool from FBbase. Don't need to guess which fluorescent protein people were using. Just run FB Blast.
www.fpbase.org/blast/
www.fpbase.org/blast/
FPbase Fluorescent Protein Sequence BLAST
Search the database at FPbase for fluorescent protein sequences similar to a query amino acid or nucleotide sequence.
www.fpbase.org
October 17, 2025 at 12:52 AM
This week I've been designing constructs and what I found very helpful is the Fluorescent Protein BLAST tool from FBbase. Don't need to guess which fluorescent protein people were using. Just run FB Blast.
www.fpbase.org/blast/
www.fpbase.org/blast/