Giordano Lippi
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lippilab.bsky.social
Giordano Lippi
@lippilab.bsky.social
Associate professor at Scripps Research. Studying mechanisms of neuronal gene expression, with a focus on non-coding RNA
Come to the Symposium
Attending #SfN2025 in San Diego☀️? Don’t miss the Dorris Neuroscience Center Symposium at @scripps.edu, happening right before the meeting. A great lineup of speakers to kick off your SfN week. Plan your trip accordingly and register for free here:
www.eventbrite.com/e/dorris-neu...

Please amplify!
October 7, 2025 at 2:28 PM
Reposted by Giordano Lippi
In our first pitch session, Ryan Shenvi, PhD, @lippilab.bsky.social, PhD, and Li Ye, PhD, will each share their approach to understanding the brain—from neuroactive compound synthesis, to microRNAs in circuit development, to brain energetics—and will take questions after each of their pitches.
September 8, 2025 at 5:16 PM
How fitting that the Preview of our Neuron paper was written by the one and only Roy Sillitoe. I saw him giving a talk at the 2018 Neural Development GRC, and his incredible data, storytelling, and enthusiasm convinced me to use Purkinje Cells as a model system.
www.cell.com/neuron/fullt...
Rooted in regulation: MicroRNAs as gardeners of the Purkinje cell dendritic arbor
Zolboot et al.1 developed tools to manipulate and map microRNA function in cerebellar Purkinje cells with temporal precision, revealing key roles in dendritic development and circuit connectivity. The...
www.cell.com
May 21, 2025 at 6:33 PM
Reposted by Giordano Lippi
Postdoc opportunity in the heart of Europe! Check out the flyer below.
Join our team on an international project with Anthony Holtmaat exploring synaptic plasticity and specificity in cortical and thalamocortical circuits.
April 8, 2025 at 12:48 PM
Reposted by Giordano Lippi
The Lipp Lab (@lippilab.bsky.social) has uncovered how microRNAs guide the development of Purkinje cells—rare neurons tied to movement and autism.

Published in Neuron, a @cellpress.bsky.social journal, the study maps how precise timing and gene regulation shape these cells’ identity and structure.
How microRNAs act as a “blueprint” for the developing brain
www.scripps.edu
April 3, 2025 at 6:24 PM
Delighted to see our paper finally out in @cp-neuron.bsky.social! Together with Ian MacRae, we developed a new toolbox to study microRNAs and used it to find new mechanisms of Purkinje cell development. Please see the tweetorial from researcher extraordinaire @norjin.bsky.social for details.
✨So happy to see part of my PhD work with @lippilab.bsky.social out today in @cp-neuron.bsky.social! ✨

We developed new tools to study microRNA-target networks with greater spatial and temporal resolution and found neuronal subtype- and developmental stage-specific roles:
MicroRNA mechanisms instructing Purkinje cell specification
Zolboot et al. introduce DD-T6B and SAP-seq, methods for investigating microRNA function with enhanced spatiotemporal resolution, and identify Purkinje cell-specific microRNAs and targets instructing ...
www.cell.com
April 2, 2025 at 7:47 PM
Congratulations Dr. Du! The second student of the Lippi lab to successfully defend her PhD. Very proud PI. And of course, we celebrate in style.
February 25, 2025 at 1:20 AM