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Scripps Research
@scripps.edu
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Scripps Research is one of the world's largest, private, non-profit biomedical research organizations. We are Science Changing Life.
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Scripps Research @scripps.edu · Jun 17
A major concern this flu season is reassortment, when seasonal flu and bird flu infect the same host and swap genetic material, potentially creating a new, more dangerous strain. With H5N1 in cows and human cases emerging, our virology labs are closely tracking its evolution. More: ow.ly/thLP50WafhH
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Scripps Research @scripps.edu · 21h
New in @nature.com: The brainstem may hold an “off switch” for chronic pain. Research co-led by neuroscientist Ann Kennedy (@antihebbiann.bsky.social) reveals how the parabrachial nucleus can silence persistent pain signals when survival demands it, hinting at new ways to treat chronic pain.
A parabrachial hub for need-state control of enduring pain - Nature
Activity in a set of parabranchial neurons in the mouse brain is increased during chronic pain, predicts coping behaviour, and can be modulated by circuits activated by survival threats.
www.nature.com
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Scripps Research @scripps.edu · 1d
Congrats to @ardemp.bskyverified.social, @liye-tsri.bsky.social & @xinjin.bsky.social on receiving the NIH Director’s Transformative Research Award!

In collaboration with the @alleninstitute.org, the team will decode interoception and create the first atlas of how sensory neurons connect to organs.
Scripps Research-led team receives $14.2M NIH award to map the body’s “hidden sixth sense”
www.scripps.edu
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Scripps Research @scripps.edu · 1d
Researchers have long wondered how type 1 diabetes begins. New findings from Scripps Research identified unique cells with protective properties that may help explain this early tolerance and offer clues for intervention.
Scripps Research discovery could improve type 1 diabetes prevention and treatment
www.scripps.edu
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Scripps Research @scripps.edu · 4d
Through years of collaboration, Scripps Research helped develop an implant that delivers a protective protein to the retina. Clinical trials show the device slows disease progression over 24 months and stays active for 14+ years.
Study confirms long-term benefit of implant for blinding eye disease
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Scripps Research @scripps.edu · 4d
An optical coherence tomography (OCT) scan shows the damage beneath the retinal surface in MacTel, where cystic spaces form and disrupt how the eye processes light. The disease progresses slowly, often without symptoms, but eventually impacts reading, facial recognition, and daily tasks.
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Scripps Research @scripps.edu · 4d
Macular telangiectasia type 2 (MacTel) gradually damages light-sensing cells in the retina, leading to vision loss. Scripps Research helped uncover its cause—and supported the first FDA-approved implant to treat it. 🧵
FDA approves ENCELTO, a first-of-its-kind eye implant that slows vision loss in rare eye disease
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Scripps Research @scripps.edu · 5d
The NIH has awarded a $14.2M Director’s Transformative Research Award to a team led by Nobel Prize-winning neuroscientist @ardemp.bskyverified.social, Prof. @liye-tsri.bsky.social and Assoc. Prof. @xinjin.bsky.social to map interoception and build the first atlas of this hidden sixth sense.
Scripps Research-led team receives $14.2M NIH award to map the body’s “hidden sixth sense”
www.scripps.edu
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Reposted by Scripps Research
antihebbiann.bsky.social
Ann Kennedy @antihebbiann.bsky.social · 6d
Finally out: our recent work with Nick Betley is a view into how the brain reshapes its behavior in the face of competing survival needs- and also a potential angle on treatment targets for enduring pain.

A brief rundown...

www.nature.com/articles/s41...
A parabrachial hub for need-state control of enduring pain - Nature
Activity in a set of parabranchial neurons in the mouse brain is increased during chronic pain, predicts coping behaviour, and can be modulated by circuits activated by survival threats.
www.nature.com
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scripps.edu
Scripps Research @scripps.edu · 6d
A new @pnas.org study from Marco Mravic’s lab describes a computer-guided strategy to design synthetic membrane proteins, revealing how a conserved amino acid motif forms stabilizing hydrogen bonds that help proteins stay folded in lipid, even under boiling conditions.
Scripps Research scientists unlock new patterns of protein behavior in cell membranes
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Scripps Research @scripps.edu · 8d
Former Scripps Research assistant professor Shimon Sakaguchi has been awarded the 2025 #NobelPrize for discovering regulatory T cells—work that reshaped immunology and inspired therapies now in clinical trials for cancer, autoimmune disease and transplant complications.
Former Scripps Research assistant professor awarded 2025 Nobel Prize in Physiology or Medicine
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Scripps Research @scripps.edu · 8d
The Fall 2025 edition of Scripps Research Magazine is here—featuring how the Skaggs Graduate School is enhancing graduate education in chemical and biological science and features alumni whose contributions are advancing discoveries across academia, industry and beyond.
Fall 2025 - Scripps Research Magazine
Learning today, leading tomorrowFrom innovative outreach programs to a nationally ranked graduate school, Scripps Research leads the way in educating the scientists of tomorrow.
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thetransmitter.bsky.social
The Transmitter @thetransmitter.bsky.social · 20d
In this episode of “Brain Inspired,” @braininspired.bsky.social talks to @antihebbiann.bsky.social, who argues that molecular signaling, like protein expression, controls innate brain responses to varying environmental contexts.

#neuroskyence

www.thetransmitter.org/brain-inspir...
Ann Kennedy explains the theoretical neuroscience of survival behaviors
The Scripps neuroscientist calls for a broader theoretical neuroscience approach in her area of research, which focuses on how the subcortex bridges life and cognition.
www.thetransmitter.org
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scripps.edu
Scripps Research @scripps.edu · 11d
Join in person on the Scripps Research campus or attend virtually via Zoom on Wednesday, October 8, 2025 at 4:00 p.m. PT | 7:00 p.m. ET.

🎟️ Registration is free! Reserve your seat now using the links below.

💻 Virtual: ow.ly/p4Ov50X6khV

📍 In-person: ow.ly/3hbv50X6kgW
The Front Row at Scripps Research: lecture with Howard Hang, PhD
Take a seat in the front row and listen as some of the world’s foremost scientists introduce you to innovative medicines and treatments.
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Scripps Research @scripps.edu · 11d
#DidYouKnow: Your gut is home to trillions of microbes that help shape your immune system 🧫

In our next Front Row lecture, Scripps Research professor Howard Hang will explore how microbial metabolites influence immunity and what this means for treating infection, cancer and chronic inflammation.
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Reposted by Scripps Research
xinjin.bsky.social
Xin Jin @xinjin.bsky.social · 12d
Actively hiring! Video made by Sora-2 but the job post is 100% real.

Apply here: hhmi.wd1.myworkdayjobs.com/en-US/Extern...
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Scripps Research @scripps.edu · 12d
The Jin Lab is also hiring a Research Specialist to design and run genomic assays, manage collaborative projects, and help drive discoveries into how genes shape the brain.

Apply now at: hhmi.wd1.myworkdayjobs.com/en-US/Extern...
Research Specialist - Jin Lab
Primary Work Address: 10550 North Torrey Pines Road, La Jolla, CA, 92037 Current HHMI Employees, click here to apply via your Workday account. The Howard Hughes Medical Institute (HHMI) advances the d...
hhmi.wd1.myworkdayjobs.com
scripps.edu
Scripps Research @scripps.edu · 12d
Scripps Research Associate Prof. Xin Jin (@xinjin.bsky.social) has been named one of only 30 @hhmi.org Freeman Hrabowski Scholars, recognized for advancing genomic tools—including in vivo Perturb-seq—to map how genes shape brain circuits and uncover clues to neurological disease and brain health.
Scripps Research associate professor named an HHMI Freeman Hrabowski Scholar
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scripps.edu
Scripps Research @scripps.edu · 19d
In back-to-back @science.org and @nature.com studies, Phil Baran’s lab reveals a radical cross-coupling method using sulfonyl hydrazides—enabling seven new reactions, pharma adoption, and the ability to retain about 90% of a molecule’s 3D shape.

More at: ow.ly/CAh450X1Qmt
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Scripps Research @scripps.edu · 21d
Congrats to Scripps Research Prof. @donnablack.bsky.social on being elected to @raeng.org.uk for her work in developing Reaction Progress Kinetic Analysis (RPKA) and research in molecular chirality—shaping both drug development and our understanding of life’s chemical origins. ow.ly/uefs50X1exY
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Scripps Research @scripps.edu · 22d
The paraventricular nucleus of the thalamus (PVT), a brain region linked to stress, may explain why people relapse even when alcohol no longer feels rewarding.

A recent study from Scripps Research shows it activates when alcohol relieves withdrawal, driving negative reinforcement in the brain.
Researchers find brain region that fuels compulsive drinking
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Scripps Research @scripps.edu · 25d
Read more at: ow.ly/r2Ap50WZykX
Wearable devices could revolutionize pregnancy monitoring and detect abnormalities
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Scripps Research @scripps.edu · 25d
Wearables like Apple Watch & Fitbit may help monitor pregnancy. ⌚️

A study in @ebiomedicine.bsky.social led by Giorgio Quer & Tolúwalàṣẹ Àjàyí (@laseajayi.com) found heart rate tracked by wearables aligned with hormone changes, offering potential for early detection and improved remote care access.
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Scripps Research @scripps.edu · 26d
The wait is almost over—#IBDCuttingEdge2025 starts tomorrow!

Join @scrippshealth.bsky.social, @ucsdmedschool.bsky.social & @crohnscolitisfdn.bsky.social for a three-day CME event on translational science, clinical trials, surgery & drug discovery in IBD care.

🎟️ Secure your spot: ow.ly/4FPU50VFUGW
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Scripps Research @scripps.edu · 27d
Today at 4 p.m. PT, join us for a new Front Row with Benjamin Cravatt, PhD. He’ll share how chemical biology is expanding access to targets once thought undruggable. Free and open to the public, online or in person. Registration is free! 🎟️

💻 Virtual: ow.ly/8Xbn50WYqNQ
📍 In-person: ow.ly/AOjk50WYqNq
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Scripps Research @scripps.edu · 27d
In our last Front Row, Travis Young, PhD, shared how Scripps Research is developing switchable CAR-T cells that activate only with a companion molecule. The design could help prevent neurological side effects and enable retreatment without reengineering.

Watch the full lecture: ow.ly/TQAq50WYqrQ
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