Lennart Schada von Borzyskowski
@lennartschada.bsky.social
Assistant Professor at the Institute of Biology Leiden | Microbial biochemistry, synthetic biology, environmental sustainability
Reposted by Lennart Schada von Borzyskowski
Our team met at Córdoba to kick off our @horizoneu.bsky.social project last month! 🇪🇺
“It was a fantastic opportunity for everyone to dive into the plans for metabolic engineering of cyanobacteria.”
Partners sharer their experience and roles in the C5 project.
Thank you for hosting us @uco.es!
“It was a fantastic opportunity for everyone to dive into the plans for metabolic engineering of cyanobacteria.”
Partners sharer their experience and roles in the C5 project.
Thank you for hosting us @uco.es!
December 18, 2025 at 3:22 PM
Our team met at Córdoba to kick off our @horizoneu.bsky.social project last month! 🇪🇺
“It was a fantastic opportunity for everyone to dive into the plans for metabolic engineering of cyanobacteria.”
Partners sharer their experience and roles in the C5 project.
Thank you for hosting us @uco.es!
“It was a fantastic opportunity for everyone to dive into the plans for metabolic engineering of cyanobacteria.”
Partners sharer their experience and roles in the C5 project.
Thank you for hosting us @uco.es!
Last week, I attended the kick-off meeting for our EU-funded C5 project in Cordoba, Spain. It was great to discuss our plans for the metabolic engineering of Cyanobacteria in detail with all partners, and I really enjoyed the visit to sunny Andalusia.
November 28, 2025 at 9:58 AM
Last week, I attended the kick-off meeting for our EU-funded C5 project in Cordoba, Spain. It was great to discuss our plans for the metabolic engineering of Cyanobacteria in detail with all partners, and I really enjoyed the visit to sunny Andalusia.
Reposted by Lennart Schada von Borzyskowski
GlcNAc build-up acts as a key metabolic signal in #Streptomyces, but how does it triggers developmental responses? @gillesvanwezel.bsky.social &co show that the enzyme NagS dehydrates GlcNAc-6P into a reactive intermediate, triggering a toxicity-based checkpoint @plosbiology.org 🧪 plos.io/44pE08I
November 27, 2025 at 5:28 PM
GlcNAc build-up acts as a key metabolic signal in #Streptomyces, but how does it triggers developmental responses? @gillesvanwezel.bsky.social &co show that the enzyme NagS dehydrates GlcNAc-6P into a reactive intermediate, triggering a toxicity-based checkpoint @plosbiology.org 🧪 plos.io/44pE08I
Recently, I had the pleasure of presenting our work at the first CO2FIX conference in Tianjin, China. It was great to see how seriously this research area is taken in China and how breakthroughs in research are rapidly moving towards large-scale applications in biotechnology.
October 21, 2025 at 1:54 PM
Recently, I had the pleasure of presenting our work at the first CO2FIX conference in Tianjin, China. It was great to see how seriously this research area is taken in China and how breakthroughs in research are rapidly moving towards large-scale applications in biotechnology.
Please share: I am hiring a postdoc that will work on enzyme characterization and engineering in the frame of the EU consortium project C5.
Read all details here and apply until August 10: www.universiteitleiden.nl/en/vacancies...
Read all details here and apply until August 10: www.universiteitleiden.nl/en/vacancies...
Postdoctoral researcher on enzyme characterization and enzyme engineering
The Faculty of Science / the Institute for Biology is looking for a: Postdoctoral researcher on enzyme characterization and enzyme engineering Vacancy number: 15834 Project description We are hiring...
www.universiteitleiden.nl
July 8, 2025 at 10:18 AM
Please share: I am hiring a postdoc that will work on enzyme characterization and engineering in the frame of the EU consortium project C5.
Read all details here and apply until August 10: www.universiteitleiden.nl/en/vacancies...
Read all details here and apply until August 10: www.universiteitleiden.nl/en/vacancies...
Reposted by Lennart Schada von Borzyskowski
Great collaboration with @lennartschada.bsky.social on an #enzyme converting the #plastic component ethylene glycol and to a feedstock chemical for microbes. Offering new ways to use plastic biotechnologically. 🧪
Ethylene glycol is widely used as monomer of the plastic PET. It is therefore highly relevant as sustainable feedstock for microbial biotechnology. In our new paper in @natcomms.nature.com, we characterize efficient enzymes for ethylene glycol oxidation: www.nature.com/articles/s41...
July 3, 2025 at 12:25 PM
Great collaboration with @lennartschada.bsky.social on an #enzyme converting the #plastic component ethylene glycol and to a feedstock chemical for microbes. Offering new ways to use plastic biotechnologically. 🧪
Reposted by Lennart Schada von Borzyskowski
Ecogenomics and functional biogeography of the Roseobacter group in the global oceans based on 653 MAGs and SAGs www.biorxiv.org/content/10.1... #jcampubs 🌊
July 2, 2025 at 3:39 PM
Ecogenomics and functional biogeography of the Roseobacter group in the global oceans based on 653 MAGs and SAGs www.biorxiv.org/content/10.1... #jcampubs 🌊
Ethylene glycol is widely used as monomer of the plastic PET. It is therefore highly relevant as sustainable feedstock for microbial biotechnology. In our new paper in @natcomms.nature.com, we characterize efficient enzymes for ethylene glycol oxidation: www.nature.com/articles/s41...
July 1, 2025 at 2:57 PM
Ethylene glycol is widely used as monomer of the plastic PET. It is therefore highly relevant as sustainable feedstock for microbial biotechnology. In our new paper in @natcomms.nature.com, we characterize efficient enzymes for ethylene glycol oxidation: www.nature.com/articles/s41...
I am happy to share that a joint EIC Pathfinder Challenges project has been funded. The C5 consortium will develop disruptive technology for the sustainable production of isoprene from carbon dioxide.
Stay tuned for more updates and open positions.
cordis.europa.eu/project/id/1...
Stay tuned for more updates and open positions.
cordis.europa.eu/project/id/1...
Clever Combination of Synthetic Compartmentalization, Carbon Fixation and Compound Biomanufacturing | C5 | Projekt | Fact Sheet | HORIZON | CORDIS | European Commission
The C5 Pathfinder project aims to revolutionize the production of bio-based chemicals by leveraging synthetic compartmentalization and metabolic engineering within photosynthetic cyanobacterial system...
cordis.europa.eu
June 26, 2025 at 3:02 PM
I am happy to share that a joint EIC Pathfinder Challenges project has been funded. The C5 consortium will develop disruptive technology for the sustainable production of isoprene from carbon dioxide.
Stay tuned for more updates and open positions.
cordis.europa.eu/project/id/1...
Stay tuned for more updates and open positions.
cordis.europa.eu/project/id/1...
Reposted by Lennart Schada von Borzyskowski
1/3 Although the issue of releasing GMOs for env bioremediation has been virtually absent of the mainstream scientific literature in Europe/US for >20 yrs, the topic has continued strong in Asia—alas in less fancy/visible journals. Time to revisit the subject in view of new global challenges 💪🏻!
June 1, 2025 at 8:52 AM
1/3 Although the issue of releasing GMOs for env bioremediation has been virtually absent of the mainstream scientific literature in Europe/US for >20 yrs, the topic has continued strong in Asia—alas in less fancy/visible journals. Time to revisit the subject in view of new global challenges 💪🏻!
Genetically enhanced bacteria can potentially become an effective tool for bioremediation in the future. Recently, an exciting breakthrough study about an engineered strain of the marine bacterium Vibrio natriegens was published in @nature.com: www.nature.com/articles/s41...
Bioremediation of complex organic pollutants by engineered Vibrio natriegens - Nature
A synthetic biology approach was used to engineer Vibrio natriegens into a strain capable of bioremediating complex organic pollutants in saline wastewater and soils, thereby addressing notable threat...
www.nature.com
May 19, 2025 at 12:31 PM
Genetically enhanced bacteria can potentially become an effective tool for bioremediation in the future. Recently, an exciting breakthrough study about an engineered strain of the marine bacterium Vibrio natriegens was published in @nature.com: www.nature.com/articles/s41...
@dirktischler.bsky.social is opening the @vaam-microbes.bsky.social conference 2025 at @ruhr-uni-bochum.de. Looking forward to three days of presentations, posters, and networking!
March 23, 2025 at 2:25 PM
@dirktischler.bsky.social is opening the @vaam-microbes.bsky.social conference 2025 at @ruhr-uni-bochum.de. Looking forward to three days of presentations, posters, and networking!
Only one week left to apply for this exciting PhD position, supervised by @gillesvanwezel.bsky.social and me!
Please apply if you are interested in microbial biochemistry and have a solid background in enzymes, metabolic pathways, and bacterial genetics.
www.universiteitleiden.nl/en/vacancies...
Please apply if you are interested in microbial biochemistry and have a solid background in enzymes, metabolic pathways, and bacterial genetics.
www.universiteitleiden.nl/en/vacancies...
PhD aminosugar metabolism
The Faculty of Science / the Institute for Biology is looking for a :PhD Candidate , Aminosugar metabolism and control of growth and development in bacteriaVacancy number: 15487 PhD project descriptio...
www.universiteitleiden.nl
March 6, 2025 at 5:08 PM
Only one week left to apply for this exciting PhD position, supervised by @gillesvanwezel.bsky.social and me!
Please apply if you are interested in microbial biochemistry and have a solid background in enzymes, metabolic pathways, and bacterial genetics.
www.universiteitleiden.nl/en/vacancies...
Please apply if you are interested in microbial biochemistry and have a solid background in enzymes, metabolic pathways, and bacterial genetics.
www.universiteitleiden.nl/en/vacancies...
Reposted by Lennart Schada von Borzyskowski
NEW: 2024 has just been confirmed as the warmest year on record, and the first to breach the 1.5C threshold.
We used a ridgeline (Joy Division inspired) chart to visualise daily temperature anomalies since 1940.
2024 clearly stands out with 100% of its days above 1.3C and 75% above 1.5C.
We used a ridgeline (Joy Division inspired) chart to visualise daily temperature anomalies since 1940.
2024 clearly stands out with 100% of its days above 1.3C and 75% above 1.5C.
January 10, 2025 at 8:04 AM
NEW: 2024 has just been confirmed as the warmest year on record, and the first to breach the 1.5C threshold.
We used a ridgeline (Joy Division inspired) chart to visualise daily temperature anomalies since 1940.
2024 clearly stands out with 100% of its days above 1.3C and 75% above 1.5C.
We used a ridgeline (Joy Division inspired) chart to visualise daily temperature anomalies since 1940.
2024 clearly stands out with 100% of its days above 1.3C and 75% above 1.5C.
Reposted by Lennart Schada von Borzyskowski
Here's the Chancellor candidate of the German Greens, Robert Habeck, stating what everyone needs to know. Namely that a strong EU is the best counterweight to authoritarians like Musk and Trump. Which is why they support those parties that want to weaken the EU.
[with English subtitles]
[with English subtitles]
January 5, 2025 at 12:56 AM
Here's the Chancellor candidate of the German Greens, Robert Habeck, stating what everyone needs to know. Namely that a strong EU is the best counterweight to authoritarians like Musk and Trump. Which is why they support those parties that want to weaken the EU.
[with English subtitles]
[with English subtitles]
Reposted by Lennart Schada von Borzyskowski
Synbio across environmental scales! By @ricardsole.bsky.social et al. doi.org/10.1021/acss...
Synthetic Ecosystems: From the Test Tube to the Biosphere
The study of ecosystems, both natural and artificial, has historically been mediated by population dynamics theories. In this framework, quantifying population numbers and related variables (associate...
doi.org
December 4, 2024 at 3:58 PM
Synbio across environmental scales! By @ricardsole.bsky.social et al. doi.org/10.1021/acss...
Reposted by Lennart Schada von Borzyskowski
Not all Bradyrhizobium fix N2! In fact, most that live in soil probably don’t. We isolated a bunch from Arizona soils and found none had N-fixing or nodulation genes. We report their genomes and phylogeny here in an accepted paper at access microbiology! www.microbiologyresearch.org/content/jour...
High-quality PacBio draft genome sequences of 17 free-living Bradyrhizobium and four related Nitrobacteraceae strains isolated from arid soils in the Santa Catalina Mountains of Southern Arizona.
Non-symbiotic Bradyrhizobium are among the most abundant and ubiquitous microbes in bulk soils globally. Despite this, most available genomic resources for Bradyrhizobium are derived from plant-associ...
www.microbiologyresearch.org
December 3, 2024 at 4:20 PM
Not all Bradyrhizobium fix N2! In fact, most that live in soil probably don’t. We isolated a bunch from Arizona soils and found none had N-fixing or nodulation genes. We report their genomes and phylogeny here in an accepted paper at access microbiology! www.microbiologyresearch.org/content/jour...
Reposted by Lennart Schada von Borzyskowski
Would you like to see @biorxivpreprint.bsky.social add a share to blue sky button?! I know I would! Share this post to let @richardsever.bsky.social @erictopol.bsky.social and others at bioarxiv know!
December 2, 2024 at 12:10 PM
Would you like to see @biorxivpreprint.bsky.social add a share to blue sky button?! I know I would! Share this post to let @richardsever.bsky.social @erictopol.bsky.social and others at bioarxiv know!
Reposted by Lennart Schada von Borzyskowski
Which one are you?
Among scientists are collectors, classifiers, and compulsive tidiers-up; many are detectives by temperament and many are explorers; some are artists and others artisans. There are poet-scientists and philosopher-scientists and even a few mystics.
–Peter Medawar
Among scientists are collectors, classifiers, and compulsive tidiers-up; many are detectives by temperament and many are explorers; some are artists and others artisans. There are poet-scientists and philosopher-scientists and even a few mystics.
–Peter Medawar
November 29, 2024 at 11:47 PM
Which one are you?
Among scientists are collectors, classifiers, and compulsive tidiers-up; many are detectives by temperament and many are explorers; some are artists and others artisans. There are poet-scientists and philosopher-scientists and even a few mystics.
–Peter Medawar
Among scientists are collectors, classifiers, and compulsive tidiers-up; many are detectives by temperament and many are explorers; some are artists and others artisans. There are poet-scientists and philosopher-scientists and even a few mystics.
–Peter Medawar
Reposted by Lennart Schada von Borzyskowski
The denitrification ability and #nitrogen metabolism pathway of aerobic #denitrifier Marinobacter alkaliphilus SBY-1 under low C/N ratios doi.org/10.1016/j.sc...
November 29, 2024 at 8:51 AM
The denitrification ability and #nitrogen metabolism pathway of aerobic #denitrifier Marinobacter alkaliphilus SBY-1 under low C/N ratios doi.org/10.1016/j.sc...
Reposted by Lennart Schada von Borzyskowski
Sign of the times, no more bluebird on the biorxiv engagement tab..
November 24, 2024 at 9:59 AM
Sign of the times, no more bluebird on the biorxiv engagement tab..
Reposted by Lennart Schada von Borzyskowski
🌐 We just joined Bluesky! SEVA is a free, open-access plasmid repository and an international standard supporting the synthetic biology community. Catch us here! #SynBio ⬇️ seva-plasmids.com
Home - SEVA plasmids - Standard European Vector Architecture
Standard European
Vector Architecture 4.0
Welcome to the CNB-hosted database and material repository of standard and modular plasmid vectors for (de/re) constructing complex bacterial phenotypes ...
seva-plasmids.com
November 22, 2024 at 1:19 PM
🌐 We just joined Bluesky! SEVA is a free, open-access plasmid repository and an international standard supporting the synthetic biology community. Catch us here! #SynBio ⬇️ seva-plasmids.com
Reposted by Lennart Schada von Borzyskowski
Started creating a synthetic biology starter pack. Still missing many so reply here if I forgot you or someone else.
go.bsky.app/SjfpxTK #synbio
go.bsky.app/SjfpxTK #synbio
November 12, 2024 at 12:30 AM
Started creating a synthetic biology starter pack. Still missing many so reply here if I forgot you or someone else.
go.bsky.app/SjfpxTK #synbio
go.bsky.app/SjfpxTK #synbio
Reposted by Lennart Schada von Borzyskowski
We created a starter pack of the members of our Leiden Early Drug Discovery and Development (LED3) hub. Follow our scientists to hear more about their exciting science:
go.bsky.app/EJByPDg
If you are in LED3 and on bluesky, but not in here, please reply to this.
Our Starter Pack includes:
(1/3)
go.bsky.app/EJByPDg
If you are in LED3 and on bluesky, but not in here, please reply to this.
Our Starter Pack includes:
(1/3)
November 19, 2024 at 11:01 AM
We created a starter pack of the members of our Leiden Early Drug Discovery and Development (LED3) hub. Follow our scientists to hear more about their exciting science:
go.bsky.app/EJByPDg
If you are in LED3 and on bluesky, but not in here, please reply to this.
Our Starter Pack includes:
(1/3)
go.bsky.app/EJByPDg
If you are in LED3 and on bluesky, but not in here, please reply to this.
Our Starter Pack includes:
(1/3)
Reposted by Lennart Schada von Borzyskowski
We strongly suggest that academic publishers and other platforms that host research rapidly implement a Share to Bluesky button for their articles. Here's how:
docs.bsky.app/docs/advance...
#AcademicSky #HigherEd #Altmetrics
docs.bsky.app/docs/advance...
#AcademicSky #HigherEd #Altmetrics
Action Intent Links | Bluesky
Authors, websites, and apps can use action intent links to implement "Share on Bluesky" buttons, or similar in-app actions. Logged-in users will be directed to the corresponding action view in the Blu...
docs.bsky.app
November 18, 2024 at 2:48 PM
We strongly suggest that academic publishers and other platforms that host research rapidly implement a Share to Bluesky button for their articles. Here's how:
docs.bsky.app/docs/advance...
#AcademicSky #HigherEd #Altmetrics
docs.bsky.app/docs/advance...
#AcademicSky #HigherEd #Altmetrics