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Reposted by Jeremy Jacobs, MD, MHS, FASCP

Raza @transfusion.health · Aug 26

“This trial adds to the growing body of evidence suggesting no clinically meaningful benefit to albumin administration in the resuscitation of septic patients”

REBEL EM @rebel-em.bsky.social · Aug 26

🧪 ICARUS-ED: Early albumin in sepsis?
📉 Minor gains in numbers, no real outcome benefit
💰 30x the cost vs crystalloids
⚠️ Outcomes > optics

🔍 Full breakdown: https://wp.me/pdrP8b-5oc
❤️ Like 🔁 Repost 🔔 Follow for more
#FOAMed #MedX #MedTwitter #MedEd

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Jeremy Jacobs, MD, MHS, FASCP @jwjacobs12.bsky.social · Aug 25

Our most recent article hits particularly close to home for me. Had the OBBB passed 10 years ago, it’s unlikely that I would have been able to attend medical school. The new changes threaten to “make the rich, richer”.

JAMA @jama.com · Aug 25

Viewpoint: The One Big Beautiful Bill Act's federal loan caps may exacerbate socioeconomic disparities in #MedEd, worsening the Matthew Effect and hindering diversity and equity within the physician workforce.

ja.ma/45xfUKn

A JAMA article titled "Federal Student Loan Limits and Implications for Physician Workforce Diversity" by Jeremy W. Jacobs and Garrett S. Booth, published online August 25, 2025. It discusses the Matthew Effect and federal loan policies.

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Reposted by Jeremy Jacobs, MD, MHS, FASCP

The BMJ @bmj.com · Aug 18

The Annals of Internal Medicine has refused US health secretary Robert F Kennedy Jr’s demand to retract a study that found that vaccines containing the adjuvant aluminium hydroxide did not increase the incidence of 50 chronic disorders, including autism and asthma
www.bmj.com/content/390/...

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Reposted by Jeremy Jacobs, MD, MHS, FASCP

PLOS Climate @plosclimate.org · Jul 21

New Opinion article by @jwjacobs12.bsky.social and Shazia Khan: "Erasing the evidence: United States climate rollbacks and the implications for public health"

journals.plos.org/climate/arti...

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Reposted by Jeremy Jacobs, MD, MHS, FASCP

Raza @transfusion.health · Jun 18

Blood is shared across legal borders to save lives.

Equitable and efficient movement of blood is guided by science and justice and must be insulated from ideologically motivated practices, argue co-authors @jwjacobs12.bsky.social @aabbupdates.bsky.social

onlinelibrary.wiley.com/doi/10.1111/...

Blood Borders: State laws, vaccine misinformation, and the threat to the United States blood supply

Click on the article title to read more.

onlinelibrary.wiley.com

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Jeremy Jacobs, MD, MHS, FASCP @jwjacobs12.bsky.social · May 23

In this Nature Medicine commentary @drgsbooth1.bsky.social and I discuss how the current political environment in the USA, including the weaponization of immigration enforcement, is impacting global scientific research, and the implications for science.

www.nature.com/articles/s41...

How US politics is undermining global science

Nature Medicine - How US politics is undermining global science

www.nature.com

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Jeremy Jacobs, MD, MHS, FASCP @jwjacobs12.bsky.social · May 14

This analysis reflects the recommendations and expertise of an international group of leaders in blood transfusion, biomedical ethics, health policy, and law. @transfusion.health @aabbupdates.bsky.social @isbt.bsky.social

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Jeremy Jacobs, MD, MHS, FASCP @jwjacobs12.bsky.social · May 14

🩸Would you want “unvaccinated” blood? Some patients now demand it—and lawmakers are listening.

Our new Annals piece warns why this shift could endanger blood safety, amplify misinformation, and erode public trust.
Read: www.acpjournals.org/doi/10.7326/...
#BloodSafety #Bioethics #Misinformation

Medical, Societal, and Ethical Considerations for Directed Blood Donation in 2025 | Annals of Internal Medicine

In the United States and other high-income countries, blood donation primarily relies on anonymous, voluntary donors. However, directed blood donation—where people donate for a specific recipient—has ...

www.acpjournals.org

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Reposted by Jeremy Jacobs, MD, MHS, FASCP

Michael Coyle @oplopanax.ca · Apr 9

In other words, the US government has suspended free speech.

NPR @npr.org · Apr 9

Effective immediately, the government says it will begin screening immigrant social media for activity that officials think indicates support for antisemitism.

U.S. says it is now monitoring immigrants' social media for antisemitism

Effective immediately, the government says it will begin screening immigrant social media for activity that officials think indicates support for antisemitism.

www.npr.org

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Jeremy Jacobs, MD, MHS, FASCP @jwjacobs12.bsky.social · Apr 9

Check out our recent viewpoint in @jama.com. The appointment of David Geier to lead the “vaccine and autism link” study, the forced resignation of Peter Marks at the FDA, and the overall leadership of RFK Jr. and Trump are literally killing Americans. We must resist this new world.

JAMA @jama.com · Apr 9

"Public health institutions must now rebuild confidence in vaccines against a backdrop of deep polarization and growing scientific illiteracy."

This Viewpoint discusses the growing influence of vaccine skeptics within public health institutions. #MedSky

Unreliable Vaccine Information and the Erosion of Science

This Viewpoint explores how appointing vaccine skeptics to positions of power in the US government contributes to the spread of unreliable information, subverts public confidence in vaccines, and unde...

jamanetwork.com

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Reposted by Jeremy Jacobs, MD, MHS, FASCP

Benjamin Mazer @mazer.us · Apr 7

The Health Secretary is promoting quack doctors in the midst of a measles outbreak and literally nothing was more predictable.

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Reposted by Jeremy Jacobs, MD, MHS, FASCP

Gabriel Winant @gabrielwinant.bsky.social · Mar 10

Here is an open letter signed from UChicago AAUP signed by over 200 faculty to our administration on what we believe this moment requires:
uchicagoaaup.wordpress.com

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Reposted by Jeremy Jacobs, MD, MHS, FASCP

Carl Quintanilla @carlquintanilla.bsky.social · Feb 28

EU foreign policy chief:

“.. Today, it became clear that the free world needs a new leader.”

@kajakallas.bsky.social

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Reposted by Jeremy Jacobs, MD, MHS, FASCP

Raza @transfusion.health · Jan 29

In this issue of NEJM Evidence, @jwjacobs12.bsky.social and I interpret the recent individual-patient meta-analysis for RBC transfusion in myocardial infarction by Carson et al and make a case for nuanced interpretation evidence.nejm.org/doi/full/10.... #medsky #transfusion

Transfusion Strategies in Myocardial Ischemia — Treat Patients, Not Numbers

Consider a relatively common clinical scenario: a 55-year-old man arrives in the emergency department after experiencing crushing retrosternal chest pain while shoveling the first snowfall of winte...

evidence.nejm.org

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Reposted by Jeremy Jacobs, MD, MHS, FASCP

Open Forum Infectious Diseases @ofidjournal.bsky.social · Dec 23

H and B Blood Antigens are Essential for In Vitro Replication of GII.2 Human Norovirus

✅ Just Accepted
#IDSky

H and B Blood Antigens are Essential for In Vitro Replication of GII.2 Human Norovirus

Human norovirus (HuNoV) is a major cause of enteric infectious gastroenteritis and is classified into several genotypes based on its capsid protein amino acid sequence and nucleotide sequence of the polymerase gene.

buff.ly

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Reposted by Jeremy Jacobs, MD, MHS, FASCP

Raza @transfusion.health · Dec 17

Our correspondence with @natureportfolio.bsky.social advocating that scholarly journals support direct link-sharing to #Bluesky amidst the exodus of academic communities from X (formerly Twitter)

@drgsbooth1.bsky.social @jwjacobs12.bsky.social @path-brian.bsky.social

www.nature.com/articles/d41...

Screenshot of correspondence with @natureportfolio.bsky.social advocating that all scholarly journals support direct link-sharing to Bluesky amidst the exodus of many academic communities from X (formerly Twitter)

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Jeremy Jacobs, MD, MHS, FASCP @jwjacobs12.bsky.social · Dec 5

Wow I had no idea! I feel like we all look to y’all as the gold standard. Hopefully one day with AI we will be able to have the ability to access antigen genotype or at least alloantibody status irrespective of country borders

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Jeremy Jacobs, MD, MHS, FASCP @jwjacobs12.bsky.social · Dec 5

Basically I always invoke Canada as the standard the US should aspire to regarding alloantibody databases, so let me know if should pick a different example 😅

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Jeremy Jacobs, MD, MHS, FASCP @jwjacobs12.bsky.social · Dec 5

I thought Canada outside of Quebec (and Quebec itself) had an alloantibody registry? Or is this just for certain patient populations (eg sickle cell disease)? Completely agree that even with ‘low’ alloimmunization rates, the issue is knowing about them once they evanesce. Cool study!

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Jeremy Jacobs, MD, MHS, FASCP @jwjacobs12.bsky.social · Dec 5

Excited to share our recent study in which we assessed whether iodinated radiocontrast media (as might be given for a CT scan) interferes with ADAMTS13 activity via the gold standard FRET method - it doesn’t, though read the open access paper for caveats. academic.oup.com/ajcp/advance...

Evaluating the potential for iodinated radiocontrast agents to interfere with ADAMTS13 activity testing via fluorescence resonance energy transfer methodology

AbstractObjectives. Fluorescence resonance energy transfer (FRET)–based ADAMTS13 activity assays are critical for the diagnosis of thrombotic thrombocytope

academic.oup.com

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Reposted by Jeremy Jacobs, MD, MHS, FASCP

Raza @transfusion.health · Dec 5

Tranexamic acid did not prevent bleeding or increase clotting in this ~600 patient RCT of heme malignancy patients (TXA was given 1 g IV every 8 hours or 1.5 g orally every 8 hours)🤷🏽‍♂️

Which is too bad--we don't have a tonne to offer these patients.. :(

www.thelancet.com/journals/lan... #transfusion

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Reposted by Jeremy Jacobs, MD, MHS, FASCP

Bluesky @bsky.app · Dec 3

Scientists, academics, researchers: We’re excited to share that @altmetric.com is now tracking mentions of your research on Bluesky! 🧪

Altmetric @altmetric.com · Dec 3

There are already many articles for which there is more attention on Bluesky than on other comparable micro-blogging sites, meaning the academic community and the general public have clearly adopted Bluesky as one of its core places to disseminate and discuss new research.

A Place of Joy.

‘A place of joy’: why scientists are joining the rush to Bluesky
Researchers say the social-media platform — an alternative to X — offers more control over the content they see and the people they engage with.: https://www.nature.com/articles/d41586-024-03784-6

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Reposted by Jeremy Jacobs, MD, MHS, FASCP

Carlos M Herrera @cmhmaliani.bsky.social · Dec 2

Good news, Altmetric has now started watching BlueSky for mentions of publications. And by the way, provides an easy comparison between this and the old site for a recent preprint of mine which I posted simultaneousl at both. Numbers speak by themselves !

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Reposted by Jeremy Jacobs, MD, MHS, FASCP

Ryan Elliott @ryanelliott.bsky.social · Dec 1

🩸Platelets!

Lifespan 7-10 days
150-450 × 10⁹/L
Stimulated by TPO
1/3 sequestered in spleen

Receptors:
GpIIbIIIa -> fibrinogen
GPIb-IX-V -> vWF
P2Y12 -> ADP

Granules:
Alpha = fibrinogen, vWF, V, VEGF, PF4, PDGF, P-selectin
Dense = ADP, Ca, Serotonin
#hemesky #MedSky

van der Meijden et al, 2019

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Reposted by Jeremy Jacobs, MD, MHS, FASCP

Raza @transfusion.health · Dec 1

Wonderful article by my mentor showing cognitive biases persist in AI chatbots, replicates known studies on biases in human and AI LLMs for comparison. Evidence that LLMs are inheriting some of our biases, in some cases quite strongly so ai.nejm.org/doi/full/10....
#mlsky #ai

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