Jack West, MD, FASCO
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jackwestmd.bsky.social
Jack West, MD, FASCO
@jackwestmd.bsky.social
Thoracic oncologist, VP of Clin Development at Summit Therapeutics, Fmr author & editor @UpToDate, founder of @cancerGRACE, interests in #DataViz & telemedicine. COI at JackWestMD.com
Reposted by Jack West, MD, FASCO
Please join us in welcoming another bright star to our 2025-2026 Patient Education Ambassadors Program: Dr. Chinmay Jani! 🌟

Dr. Jani is a Hematology-Oncology Fellow at the University of Miami/Jackson Health System. +
May 6, 2025 at 12:33 AM
Reposted by Jack West, MD, FASCO
A Warm Congratulations to Dr. Faith Abodunrin!

We are delighted to recognize Dr. Faith Abodunrin as one of our four rising stars selected for the Patient Education Ambassadors Program for the years 2025 and 2026.
April 30, 2025 at 11:55 PM
Reposted by Jack West, MD, FASCO
A 3rd place finish on beam and a 6th place finish on floor gives Mya Lauzon two more All-America accolades! 🌟

She graduates a 19x All-American, the most in Cal history!

#GoBears | #BeachBears
April 19, 2025 at 4:25 AM
That's third at NCAA Nationals!
One last piece of hardware for one of greatest gymnasts to ever don a Cal leo! 🥉

Thank you, Mya. 💙💛

#GoBears | #OneDayBetter
April 18, 2025 at 8:41 PM
So proud of my step-daughter. Amazing!🤩
One last piece of hardware for one of greatest gymnasts to ever don a Cal leo! 🥉

Thank you, Mya. 💙💛

#GoBears | #OneDayBetter
April 18, 2025 at 8:40 PM
Reposted by Jack West, MD, FASCO
Dr. Karen Yun presenting: How Do You Read a Molecular Testing Report?

What are Driver Alterations in Lung Cancer?

#TargetedTherapiesInLungCancer #LungCancer #ALK #ROS1 #RET #NTRK #EGFR #BRAF #MET #HER2 #KRAS
March 15, 2025 at 3:56 PM
I didn't know Dr. Yun before today, but she raised at UCSD with Drs. Luda Bazhenova & Sandip Patel.

She did a great job. Looking forward to seeing her career trajectory.
Dr. Karen Yun presenting: How Do You Read a Molecular Testing Report?

What are Driver Alterations in Lung Cancer?

#TargetedTherapiesInLungCancer #LungCancer #ALK #ROS1 #RET #NTRK #EGFR #BRAF #MET #HER2 #KRAS
March 15, 2025 at 9:05 PM
Several of my favorite people in thoracic oncology featured in this picture.
Q&A session with Drs. @lungoncdoc, @MMarmarelis, @LudaBazhenovaMD, and @IyengarPuneeth

Is it better to continue on the same therapy as long as possible?

#TargetedTherapiesInLungCancer #LungCancer
March 15, 2025 at 9:03 PM
Reposted by Jack West, MD, FASCO
Dr. @ChristineBestv1 now presenting: ALK, ROS1 and RET: Pushing the Boundaries of Targeted Therapies

#ALK #ROS1 #RET #LungCancer #TargetedTherapies #cancerGRACE
March 15, 2025 at 6:40 PM
Reposted by Jack West, MD, FASCO
#Smoking is associated with #KRAS (~100%) and #BRAF (50%) alterations.

• Increases cancers of upper airway, stomach, mouth, tongue, liver, cervix, bladder…

• So: Don’t start smoking+
March 15, 2025 at 7:25 PM
Reposted by Jack West, MD, FASCO
Q&A session with Drs. @lungoncdoc, @MMarmarelis, @LudaBazhenovaMD, and @IyengarPuneeth

Is it better to continue on the same therapy as long as possible?

#TargetedTherapiesInLungCancer #LungCancer
March 15, 2025 at 6:06 PM
In a self-indulgent moment, I need to say how incredibly proud I am of my stepdaughter, Mya Lauzon, who is a phenomenal gymnast, (& student, & person) at @calwgym.bsky.social: she won all-around, including a perfect 10 on floor. She is 1st Cal gymnast ever to score 10s in 3 different rotations. 😊🤩
MYA LAUZON FINISHES THE NIGHT OF HER LIFE AND CLINCHES THE BIG MEET FOR CAL WITH A PERFECT TEN ON FLOOR TO BEAT STANFORD GO BEARS FOREVER 💙💛🐻
February 10, 2025 at 12:23 AM
Great conference. I'm looking forward to seeing folks there!🤠
Register now to join my co-chair Dr. Tina Cascone & me on April 10-12, 2025 at Austin City Limits for #TexasLung25 - a 2d #CME conference with > 80 lung cancer experts discussing current standards of care. Something for everyone: oncologists, trainees, nurses, pharmacists!

thetlcconference.com
January 18, 2025 at 5:10 PM
Hats became far less common in the mid-60s, before I was on the scene, but I'm happy to be living through time when neckties become superfluous. I was just at another mtg where 90% of the men wore open collars: a good thing.

In addition to shirts, men still have socks for colorful self-expression.
January 18, 2025 at 5:05 PM
IMO, it would be helpful if safety profiles for phase 3 trials highlighted where there are significant differences between 2 arms (along w/full data of all AEs elsewhere). What do ppl think of a version like this, showing a lower number for one arm & colored arrow to higher number in the other arm?
January 9, 2025 at 8:25 PM
So amazingly proud of my step-daughter, Mya Lauzon, Cal Berkeley gymnast, who's at the top of her game now, in her senior year.

First week of the season, second in all-around behind Olympic gymnast Jade Carey, & named ACC gymnast of the week.

calbears.com/news/2025/1/...
Lauzon Named ACC Gymnast Of The Week - California Golden Bears Athletics
Senior Earns 4 Podium Finishes
calbears.com
January 8, 2025 at 2:43 AM
Working with Working Memory

The first step of internalizing new info is having it retained temporarily & “understood”. Then, some fraction may be retained in long-term memory. But working memory can’t handle >3-4 ideas at once. More overwhelms us, like juggling too many balls at one time. (1/5)
January 6, 2025 at 8:23 PM
Quite clear. Maybe now that I'm noting them more, I am seeing more examples. I think they're catching on.

Would also be a nice way to visualize evolution of acquired resistance mechanisms in pts with EGFRm+ NSCLC, etc. Could illustrate subsequent molecular findings &/or subsequent treatment.
Here's another example of Sankey graph used nicely, in a paper on molecular testing

www.nature.com/articles/s41...
January 6, 2025 at 3:22 PM
Plussing our figures
In oncology, figs like Kaplan-Meier curves, waterfall plots, & swimmer plots are central to how we interpret data. A stated HR or diff in med surv is compelling, but visual impact of a figure can make us feel it viscerally (here, CROWN trial 5-yr EFS). (1/5)
December 19, 2024 at 3:09 PM
Our slides should not be a teleprompter.
Among most common problems of slide presentations is a slide full of text (example of mine here). Why? When we see sentences of text, it’s hard for us to avoid temptation to read it verbatim, & audience reads faster than we speak. (1/8)
December 16, 2024 at 5:51 PM
My high school English teacher offered extra credit to any student who brought in a funny Nancy comic.

No student ever claimed that prize.
December 13, 2024 at 2:49 AM
“Sorry for this busy slide…”

We should discuss a common error that many of us, myself included, tend to commit. Too often we see slides contain MANY figures of different types: it’s bewildering.

The speaker may apologize, but why make slides we feel compelled to apologize for? (1/6)
December 12, 2024 at 9:57 PM
I'd encourage patients, caregivers, & even health care professionals to join this free program with a wonderful faculty this coming Saturday morning.

This is a terrific annual event, but this year has a ton of new content to provide context for. #LCSM

give.cancergrace.org/event/lung-c...
December 12, 2024 at 9:24 PM
In Praise of Sankey Charts

Lest it seem like I'm just going to criticize people's figures & slides, I want to take a moment to salute a beautifully clear, helpful figure called a Sankey chart. It's tailor-made for showing how resources (here, pts) get distributed over time/treatment.

(1 of 2)
December 10, 2024 at 12:35 AM
Point about marketing over data is important, & clinical/academic onc community is also abetting hype way too much, doing too little to underscore need for evidence that ctDNA results can actually improve clinical outcomes.

Kudos @n8pennell.bsky.social for trying to redirect the narrative.
We have known for decade+ that you can detect progression using ctDNA months before you see it on scans. But until we show that it impacts outcomes to change tx earlier all it does is make ppl anxious and abandon treatments (TKIs) that may still be helping. Most MRD use today is marketing over data.
Why aren’t more oncologists using MRD tests like Signatera or Guardant Reveal to proactively treat NSCLC before PD shows up on imaging especially in later treatment lines? www.jto.org/article/S155...
December 8, 2024 at 7:11 PM