Dr François Gravey
@fgravey.bsky.social
🧫 Clinical Microbiologist | MD, PhD 🔬 Research: #Genomics of MDR bacteria, #AMR & #OneHealth. 📍 CHU Caen, France. Sharing microbiology news, resistance cases & my publications. 🇫🇷🇬🇧
Reposted by Dr François Gravey
#NatMicroPicks
AMR plasmid evolution over a century! ⭕🧬🦠💊
Plasmids from 1917–1954 reveal over a century of evolution shaped by antibiotic industrialization
#MicroSky
www.science.org/doi/10.1126/...
AMR plasmid evolution over a century! ⭕🧬🦠💊
Plasmids from 1917–1954 reveal over a century of evolution shaped by antibiotic industrialization
#MicroSky
www.science.org/doi/10.1126/...
Pre- and postantibiotic epoch: The historical spread of antimicrobial resistance
Plasmids are now the primary vectors of antimicrobial resistance, but our understanding of how human industrialization of antibiotics influenced their evolution is limited by a paucity of data predati...
www.science.org
December 12, 2025 at 3:37 PM
#NatMicroPicks
AMR plasmid evolution over a century! ⭕🧬🦠💊
Plasmids from 1917–1954 reveal over a century of evolution shaped by antibiotic industrialization
#MicroSky
www.science.org/doi/10.1126/...
AMR plasmid evolution over a century! ⭕🧬🦠💊
Plasmids from 1917–1954 reveal over a century of evolution shaped by antibiotic industrialization
#MicroSky
www.science.org/doi/10.1126/...
🧪 Lab life question!
What antibiogram methods do you use in your lab?
🔹 Disk diffusion?
🔹 MIC strips ?
🔹 Automated systems ?
🔹 Broth microdilution ?
🔹 Or something else?
Let’s share and compare! 👇
#Microbiology #LabLife #AntimicrobialResistance #ClinicalMicrobiology #OneHealth
What antibiogram methods do you use in your lab?
🔹 Disk diffusion?
🔹 MIC strips ?
🔹 Automated systems ?
🔹 Broth microdilution ?
🔹 Or something else?
Let’s share and compare! 👇
#Microbiology #LabLife #AntimicrobialResistance #ClinicalMicrobiology #OneHealth
December 11, 2025 at 8:41 PM
🧪 Lab life question!
What antibiogram methods do you use in your lab?
🔹 Disk diffusion?
🔹 MIC strips ?
🔹 Automated systems ?
🔹 Broth microdilution ?
🔹 Or something else?
Let’s share and compare! 👇
#Microbiology #LabLife #AntimicrobialResistance #ClinicalMicrobiology #OneHealth
What antibiogram methods do you use in your lab?
🔹 Disk diffusion?
🔹 MIC strips ?
🔹 Automated systems ?
🔹 Broth microdilution ?
🔹 Or something else?
Let’s share and compare! 👇
#Microbiology #LabLife #AntimicrobialResistance #ClinicalMicrobiology #OneHealth
One of my favorite podcast 🫶 let's have a look 👀 next monday !
📣 New #Communicable drops Mon 15 Dec!
@angelahuttner.bsky.social & @marcbonten.bsky.social invite Ilan Schwartz @germhuntermd.bsky.social , Neil Stone @drneilstone.bsky.social & Tara Smith @aetiology.bsky.social to debate staying on or leaving Twitter for alternatives 🎤
#IDTwitter #IDSky #clinmicro
@angelahuttner.bsky.social & @marcbonten.bsky.social invite Ilan Schwartz @germhuntermd.bsky.social , Neil Stone @drneilstone.bsky.social & Tara Smith @aetiology.bsky.social to debate staying on or leaving Twitter for alternatives 🎤
#IDTwitter #IDSky #clinmicro
December 11, 2025 at 8:39 PM
One of my favorite podcast 🫶 let's have a look 👀 next monday !
Are horses a reservoir for high-risk Enterobacter? 🐴🏥
Our new #Genomics study reveals the presence of human clones ST114 & ST171 in equine samples.
Essential data for #OneHealth & #AMR monitoring.
📄 Read Harel et al.: doi.org/10.1371/jour...
#MicroSky #VetSci @plosone.org @anses-fr.bsky.social
Our new #Genomics study reveals the presence of human clones ST114 & ST171 in equine samples.
Essential data for #OneHealth & #AMR monitoring.
📄 Read Harel et al.: doi.org/10.1371/jour...
#MicroSky #VetSci @plosone.org @anses-fr.bsky.social
December 10, 2025 at 9:04 PM
Are horses a reservoir for high-risk Enterobacter? 🐴🏥
Our new #Genomics study reveals the presence of human clones ST114 & ST171 in equine samples.
Essential data for #OneHealth & #AMR monitoring.
📄 Read Harel et al.: doi.org/10.1371/jour...
#MicroSky #VetSci @plosone.org @anses-fr.bsky.social
Our new #Genomics study reveals the presence of human clones ST114 & ST171 in equine samples.
Essential data for #OneHealth & #AMR monitoring.
📄 Read Harel et al.: doi.org/10.1371/jour...
#MicroSky #VetSci @plosone.org @anses-fr.bsky.social
Reposted by Dr François Gravey
Reference genome choice compromises population genetic analyses - a problem for microbes too! Our lab is designing a tool to automatically choose references for input samples using features like phylogeny of reads to existing references. Any thoughts🤩? 🧪🦠🧬🖥️ #microsky
www.cell.com/cell/abstrac...
www.cell.com/cell/abstrac...
Reference genome choice compromises population genetic analyses
Using a species-specific reference genome significantly improves the accuracy of population
genetic analyses, as exemplified by mapping gray fox sequence data to genomes of several
canid species. Mapp...
www.cell.com
December 6, 2025 at 8:51 AM
Reference genome choice compromises population genetic analyses - a problem for microbes too! Our lab is designing a tool to automatically choose references for input samples using features like phylogeny of reads to existing references. Any thoughts🤩? 🧪🦠🧬🖥️ #microsky
www.cell.com/cell/abstrac...
www.cell.com/cell/abstrac...
Reposted by Dr François Gravey
The New Invasion - @fgravey.bsky.social presenting the epidemiology of carbapenem-resistant bacteria in Normandy, France
June 27, 2025 at 1:20 PM
The New Invasion - @fgravey.bsky.social presenting the epidemiology of carbapenem-resistant bacteria in Normandy, France
In France, despite medical biology contributing to 70% of medical diagnoses, a decreasing number of medical residents are choosing this specialty. However, dedicated teaching, presented in an engaging and interactive manner, has proven effective 😀
pubmed.ncbi.nlm.nih.gov/39991819/
pubmed.ncbi.nlm.nih.gov/39991819/
[How to promote medical biology to medical students: interest of interactive clinical cases in biological laboratory] - PubMed
Despite its central role in modern medicine, medical biology tends to attract fewer future physicians. The reasons for this disinterest are varied: a lack of awareness about the specialty among studen...
pubmed.ncbi.nlm.nih.gov
May 20, 2025 at 7:37 PM
In France, despite medical biology contributing to 70% of medical diagnoses, a decreasing number of medical residents are choosing this specialty. However, dedicated teaching, presented in an engaging and interactive manner, has proven effective 😀
pubmed.ncbi.nlm.nih.gov/39991819/
pubmed.ncbi.nlm.nih.gov/39991819/
Really agree with this post, amazing podcast, learned so much, thank you very much @cmicomms.bsky.social
I have never found myself taking notes during a podcast but this one was really amazing! Learning about the complexity and credibility of the trial is fascinating! Amazing job by the trial team.
A tiny mention of environmental sustainability by @angelahuttner.bsky.social made my heart melt! #IDsky
A tiny mention of environmental sustainability by @angelahuttner.bsky.social made my heart melt! #IDsky
🆕 Episode of #Breakpoints/Communicable:
Breakpoints joins forces w @cmicomms.bsky.social podcast to discuss the highly anticipated SNAP trial updates presented at ESCMID Global 2025.
Listen to Breakpoints: sidp.pinecast.co | breakpoints-sidp.org
Listen to Communicable: communicable.transistor.fm
Breakpoints joins forces w @cmicomms.bsky.social podcast to discuss the highly anticipated SNAP trial updates presented at ESCMID Global 2025.
Listen to Breakpoints: sidp.pinecast.co | breakpoints-sidp.org
Listen to Communicable: communicable.transistor.fm
May 20, 2025 at 10:24 AM
Really agree with this post, amazing podcast, learned so much, thank you very much @cmicomms.bsky.social
Reposted by Dr François Gravey
Portrait of Otelia Cromwell, the first African American woman to receive a Ph.D. from Yale University, 1926, by contemporary US painter Jennifer Packer #WomensArt
May 17, 2025 at 12:56 PM
Portrait of Otelia Cromwell, the first African American woman to receive a Ph.D. from Yale University, 1926, by contemporary US painter Jennifer Packer #WomensArt
Reposted by Dr François Gravey
Academically, I know there are massive problems with access to adequate antibiotics in LMICs, but looking at infection burden and sales of relevant antibiotics, this article estimates only 6.9% of CRGN infections are treated properly.
Truly shocking.
Truly shocking.
New article:
Estimated undertreatment of carbapenem-resistant Gram-negative bacterial infections in eight low-income and middle-income countries: a modelling study
www.thelancet.com/journals/lan...
Estimated undertreatment of carbapenem-resistant Gram-negative bacterial infections in eight low-income and middle-income countries: a modelling study
www.thelancet.com/journals/lan...
Estimated undertreatment of carbapenem-resistant Gram-negative bacterial infections in eight low-income and middle-income countries: a modelling study
Infections caused by CRGN bacteria are likely to be significantly undertreated in
LMICs. To close this treatment gap, improved access to diagnostics and antibiotics,
strengthening of health systems, a...
www.thelancet.com
May 1, 2025 at 6:44 AM
Academically, I know there are massive problems with access to adequate antibiotics in LMICs, but looking at infection burden and sales of relevant antibiotics, this article estimates only 6.9% of CRGN infections are treated properly.
Truly shocking.
Truly shocking.
Reposted by Dr François Gravey
I feel seen.
Two scientist parents who often help their children with homework deal with acceptable — and unacceptable — errors in course materials.
https://go.nature.com/3YmONh9
https://go.nature.com/3YmONh9
How we call out the infuriating mistakes we spot in school science textbooks
Two scientist parents who often help their children with homework deal with acceptable — and unacceptable — errors in course materials.
go.nature.com
April 30, 2025 at 1:44 PM
I feel seen.
Really pleased to see our students doing their first oral communications at the rencontres normandes de microbiologie today organized in Evreux. Bravo Tarcila and Blandine ! @universite-caen.bsky.social @inserm.fr
April 29, 2025 at 7:51 PM
Really pleased to see our students doing their first oral communications at the rencontres normandes de microbiologie today organized in Evreux. Bravo Tarcila and Blandine ! @universite-caen.bsky.social @inserm.fr
Reposted by Dr François Gravey
Barry Blitt’s cover for this week’s issue, “The First Hundred Days.” #NewYorkerCovers nyer.cm/ysrCZ47
April 28, 2025 at 4:20 PM
Barry Blitt’s cover for this week’s issue, “The First Hundred Days.” #NewYorkerCovers nyer.cm/ysrCZ47
This morning with my team we talked about the @angelahuttner.bsky.social pilot program in @cmicomms.bsky.social journal in which some very relevant reviewers could be add in the acknowledgments or perhaps among authors ! At the unanimity, this is an amazing idea 🙂
April 17, 2025 at 7:43 AM
This morning with my team we talked about the @angelahuttner.bsky.social pilot program in @cmicomms.bsky.social journal in which some very relevant reviewers could be add in the acknowledgments or perhaps among authors ! At the unanimity, this is an amazing idea 🙂
Reposted by Dr François Gravey
Attendees can receive certificates for attending or presenting at #ESCMIDGlobal 2025. For more info, visit the congress webpage: ow.ly/sHfa50VzNO7
Please note, you can only claim credit points once, so be sure to claim them all at the end.
Please note, you can only claim credit points once, so be sure to claim them all at the end.
April 15, 2025 at 12:53 PM
Attendees can receive certificates for attending or presenting at #ESCMIDGlobal 2025. For more info, visit the congress webpage: ow.ly/sHfa50VzNO7
Please note, you can only claim credit points once, so be sure to claim them all at the end.
Please note, you can only claim credit points once, so be sure to claim them all at the end.
Reposted by Dr François Gravey
Our May issue is now LIVE!🎊
www.nature.com/nrmicro/volu...
🔹Antibiotic-recalcitrant Salmonella during infection
🔸The consequences of SARS-CoV-2 within-host persistence
🔹Shigella sonnei: epidemiology, evolution, pathogenesis, resistance & host interactions
🔸Hepatitis B and D virus entry
www.nature.com/nrmicro/volu...
🔹Antibiotic-recalcitrant Salmonella during infection
🔸The consequences of SARS-CoV-2 within-host persistence
🔹Shigella sonnei: epidemiology, evolution, pathogenesis, resistance & host interactions
🔸Hepatitis B and D virus entry
April 16, 2025 at 3:52 PM
Our May issue is now LIVE!🎊
www.nature.com/nrmicro/volu...
🔹Antibiotic-recalcitrant Salmonella during infection
🔸The consequences of SARS-CoV-2 within-host persistence
🔹Shigella sonnei: epidemiology, evolution, pathogenesis, resistance & host interactions
🔸Hepatitis B and D virus entry
www.nature.com/nrmicro/volu...
🔹Antibiotic-recalcitrant Salmonella during infection
🔸The consequences of SARS-CoV-2 within-host persistence
🔹Shigella sonnei: epidemiology, evolution, pathogenesis, resistance & host interactions
🔸Hepatitis B and D virus entry
Very interesting discovery from an Institut Pateur team about interactions between bacterial and eukaryotic DNA cells.
#bacteria #science #insitutpateur
Sequence-dependent activity and compartmentalization of foreign DNA in a eukaryotic nucleus | Science www.science.org/doi/10.1126/...
#bacteria #science #insitutpateur
Sequence-dependent activity and compartmentalization of foreign DNA in a eukaryotic nucleus | Science www.science.org/doi/10.1126/...
Sequence-dependent activity and compartmentalization of foreign DNA in a eukaryotic nucleus
In eukaryotes, DNA-associated protein complexes coevolve with genomic sequences to orchestrate chromatin folding. We investigate the relationship between DNA sequence and the spontaneous loading and a...
www.science.org
April 16, 2025 at 6:18 AM
Very interesting discovery from an Institut Pateur team about interactions between bacterial and eukaryotic DNA cells.
#bacteria #science #insitutpateur
Sequence-dependent activity and compartmentalization of foreign DNA in a eukaryotic nucleus | Science www.science.org/doi/10.1126/...
#bacteria #science #insitutpateur
Sequence-dependent activity and compartmentalization of foreign DNA in a eukaryotic nucleus | Science www.science.org/doi/10.1126/...
Thank you very much to @drneilstone.bsky.social for your very inspiring talk this morning about the scientific presence on social medias at #escmidglobal2025. You have been heard, this is my first message on Bluesky. Let’s see how it goes 🙂
April 15, 2025 at 9:30 PM
Thank you very much to @drneilstone.bsky.social for your very inspiring talk this morning about the scientific presence on social medias at #escmidglobal2025. You have been heard, this is my first message on Bluesky. Let’s see how it goes 🙂
Reposted by Dr François Gravey
New reserach
The WHO Bacterial Priority Pathogens List 2024: a prioritisation study to guide research, development, and public health strategies against antimicrobial resistance
www.thelancet.com/journals/lan...
The WHO Bacterial Priority Pathogens List 2024: a prioritisation study to guide research, development, and public health strategies against antimicrobial resistance
www.thelancet.com/journals/lan...
The WHO Bacterial Priority Pathogens List 2024: a prioritisation study to guide research, development, and public health strategies against antimicrobial resistance
The 2024 WHO BPPL is a key tool for prioritising research and development investments
and informing global public health policies to combat AMR. Gram-negative bacteria
and rifampicin-resistant M tuber...
www.thelancet.com
April 15, 2025 at 1:16 PM
New reserach
The WHO Bacterial Priority Pathogens List 2024: a prioritisation study to guide research, development, and public health strategies against antimicrobial resistance
www.thelancet.com/journals/lan...
The WHO Bacterial Priority Pathogens List 2024: a prioritisation study to guide research, development, and public health strategies against antimicrobial resistance
www.thelancet.com/journals/lan...
Reposted by Dr François Gravey
Great talk by Ursula Hofer @hoferu.bsky.social, editor-in-chief of @thelancetinfdis.bsky.social, on #predatorypublishing. So many horrible things to learn. 😥
#ESCMIDGlobal #IDSky
#ESCMIDGlobal #IDSky
April 15, 2025 at 7:21 AM
Great talk by Ursula Hofer @hoferu.bsky.social, editor-in-chief of @thelancetinfdis.bsky.social, on #predatorypublishing. So many horrible things to learn. 😥
#ESCMIDGlobal #IDSky
#ESCMIDGlobal #IDSky
Reposted by Dr François Gravey
Another great talk! @drneilstone.bsky.social discusses how social media can serve you & communicate your research! Some great slides breaking down an effective posting strategy! 🚀
#ESCMIDGlobal #IDSky #clinmicro
#ESCMIDGlobal #IDSky #clinmicro
April 15, 2025 at 7:37 AM
Another great talk! @drneilstone.bsky.social discusses how social media can serve you & communicate your research! Some great slides breaking down an effective posting strategy! 🚀
#ESCMIDGlobal #IDSky #clinmicro
#ESCMIDGlobal #IDSky #clinmicro