Fabian Rentzsch
@fabianrentzsch.bsky.social
Developmental Biologist interested in nervous systems and evolution.
Reposted by Fabian Rentzsch
Cells can form patterns within themselves just like embryos do. How? Connie Yan's new preprint shows how the anterior-posterior cytoskeleton pattern in Stentor is dictated by regionalized scaffolding proteins
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
August 19, 2025 at 8:42 AM
Cells can form patterns within themselves just like embryos do. How? Connie Yan's new preprint shows how the anterior-posterior cytoskeleton pattern in Stentor is dictated by regionalized scaffolding proteins
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Fabian Rentzsch
1/5
🚨🚨 preprint alert! 🚨🚨
I wish to introduce CARDIB, not the singer, but the protein.
CARDIB=CARD Inhibitory Binding protein.
In our new work we discover this antiviral protein that is found in all Anthozoa (sea anemones and corals 🪸) but not in other animals.
www.biorxiv.org/content/10.1...
🚨🚨 preprint alert! 🚨🚨
I wish to introduce CARDIB, not the singer, but the protein.
CARDIB=CARD Inhibitory Binding protein.
In our new work we discover this antiviral protein that is found in all Anthozoa (sea anemones and corals 🪸) but not in other animals.
www.biorxiv.org/content/10.1...
An ancient anthozoan protein reveals an alternative evolutionary path of antiviral signaling
How antiviral immunity first arose in animals is a central question in evolutionary biology. Using the sea anemone Nematostella vectensis, we identify CARDIB, a previously uncharacterized gene located...
www.biorxiv.org
November 25, 2025 at 12:06 PM
1/5
🚨🚨 preprint alert! 🚨🚨
I wish to introduce CARDIB, not the singer, but the protein.
CARDIB=CARD Inhibitory Binding protein.
In our new work we discover this antiviral protein that is found in all Anthozoa (sea anemones and corals 🪸) but not in other animals.
www.biorxiv.org/content/10.1...
🚨🚨 preprint alert! 🚨🚨
I wish to introduce CARDIB, not the singer, but the protein.
CARDIB=CARD Inhibitory Binding protein.
In our new work we discover this antiviral protein that is found in all Anthozoa (sea anemones and corals 🪸) but not in other animals.
www.biorxiv.org/content/10.1...
Reposted by Fabian Rentzsch
Drawing together findings from several projects over many years, we make a case that neural cell types in the Clytia larva have two embryological origins: i-cells and ectodermal.
bioRxiv 2025.11.17.688882; doi: doi.org/10.1101/2025...
bioRxiv 2025.11.17.688882; doi: doi.org/10.1101/2025...
November 19, 2025 at 7:43 AM
Drawing together findings from several projects over many years, we make a case that neural cell types in the Clytia larva have two embryological origins: i-cells and ectodermal.
bioRxiv 2025.11.17.688882; doi: doi.org/10.1101/2025...
bioRxiv 2025.11.17.688882; doi: doi.org/10.1101/2025...
Very nice study on the control of pulsation in a coral, combining surgical and molecular approaches.
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
November 19, 2025 at 10:08 AM
Very nice study on the control of pulsation in a coral, combining surgical and molecular approaches.
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Reposted by Fabian Rentzsch
Congrats @corderolab.bsky.social !!
Neuroendocrine control of intestinal regeneration through the vascular niche in Drosophila: Developmental Cell www.cell.com/developmenta...
Neuroendocrine control of intestinal regeneration through the vascular niche in Drosophila: Developmental Cell www.cell.com/developmenta...
Neuroendocrine control of intestinal regeneration through the vascular niche in Drosophila
Adult intestinal plasticity and tissue repair involves complex and reciprocal multicellular
interactions. Medina, Perochon, et al. report a signaling axis between hormone-producing
cells in the intest...
www.cell.com
November 17, 2025 at 10:00 PM
Congrats @corderolab.bsky.social !!
Neuroendocrine control of intestinal regeneration through the vascular niche in Drosophila: Developmental Cell www.cell.com/developmenta...
Neuroendocrine control of intestinal regeneration through the vascular niche in Drosophila: Developmental Cell www.cell.com/developmenta...
Our paper on the role of neurons in Nematostella head regeneration is now out at @currentbiology.bsky.social Big thank you to all collaborators, it was a pleasure!
Ectopic head regeneration after nervous system ablation in a sea anemone: Current Biology www.cell.com/current-biol...
Ectopic head regeneration after nervous system ablation in a sea anemone: Current Biology www.cell.com/current-biol...
Ectopic head regeneration after nervous system ablation in a sea anemone
Via genetic ablation of neurons, Mazloumi Gavgani et al. show that the nervous system
is essential for defining axial polarity during whole-body regeneration in the sea
anemone Nematostella vectensis.
www.cell.com
November 18, 2025 at 10:00 AM
Our paper on the role of neurons in Nematostella head regeneration is now out at @currentbiology.bsky.social Big thank you to all collaborators, it was a pleasure!
Ectopic head regeneration after nervous system ablation in a sea anemone: Current Biology www.cell.com/current-biol...
Ectopic head regeneration after nervous system ablation in a sea anemone: Current Biology www.cell.com/current-biol...
Reposted by Fabian Rentzsch
In our new preprint we describe the synaptic #connectome of the nerve net in the ctenophore gravisensory organ. https://www.biorxiv.org/content/10.1101/2025.06.26.661250v1 #biology #neuroscience #ctenophore #vem
June 30, 2025 at 5:51 AM
In our new preprint we describe the synaptic #connectome of the nerve net in the ctenophore gravisensory organ. https://www.biorxiv.org/content/10.1101/2025.06.26.661250v1 #biology #neuroscience #ctenophore #vem
Reposted by Fabian Rentzsch
I am looking for a new postdoc to join the lab. Interested in pluripotency, germ cells, and in investigating these in a genetically tractable cnidarian? Get in touch! We offer a long-term contract, excellent research environment, and a lovely city #Galway. www.urifranklab.org
June 20, 2025 at 1:24 PM
I am looking for a new postdoc to join the lab. Interested in pluripotency, germ cells, and in investigating these in a genetically tractable cnidarian? Get in touch! We offer a long-term contract, excellent research environment, and a lovely city #Galway. www.urifranklab.org
Beautiful description of a ctenophore apical organ from @annaferraioli.bsky.social, @pawelburkhardt.bsky.social and @maikekittelmann.bsky.social. It will be exciting to learn more about its development!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
The 3D architecture of the ctenophore aboral organ and the evolution of complex integrative centers in animals
The ability to sense and respond to environmental cues is fundamental to animal behavior and survival. In ctenophores - early-branching marine animals - a syncytial nerve net underlies complex behavio...
www.biorxiv.org
June 27, 2025 at 12:53 PM
Beautiful description of a ctenophore apical organ from @annaferraioli.bsky.social, @pawelburkhardt.bsky.social and @maikekittelmann.bsky.social. It will be exciting to learn more about its development!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Fabian Rentzsch
Congratulations Zonglai, @hoyerjorgen.bsky.social & @mchatzigeorgiou.bsky.social 👏
Read the full article ⤵️
Read the full article ⤵️
Anoctamins mediate polymodal sensory perception and larval metamorphosis in a non-vertebrate chordate
Liang et al. report that Ano5 and Ano6 are required for sensing and responding to
mechanical and chemical cues that mediate larval settlement and metamorphosis in the
invertebrate chordate Ciona intes...
tinyurl.com
April 25, 2025 at 11:58 AM
Congratulations Zonglai, @hoyerjorgen.bsky.social & @mchatzigeorgiou.bsky.social 👏
Read the full article ⤵️
Read the full article ⤵️
Reposted by Fabian Rentzsch
My group is hiring a new Postdoc to work on gene regulation and chromatin in Nematostella. Please RT!
For more information see here:
gahanlab.com
tinyurl.com/34xke35d
For more information see here:
gahanlab.com
tinyurl.com/34xke35d
April 8, 2025 at 12:09 PM
My group is hiring a new Postdoc to work on gene regulation and chromatin in Nematostella. Please RT!
For more information see here:
gahanlab.com
tinyurl.com/34xke35d
For more information see here:
gahanlab.com
tinyurl.com/34xke35d
Reposted by Fabian Rentzsch
Great opportunity for a post-doc to join the University of Galway in the research team of our committee member @jgahan.bsky.social!
My group is hiring a new Postdoc to work on gene regulation and chromatin in Nematostella. Please RT!
For more information see here:
gahanlab.com
tinyurl.com/34xke35d
For more information see here:
gahanlab.com
tinyurl.com/34xke35d
April 8, 2025 at 12:19 PM
Great opportunity for a post-doc to join the University of Galway in the research team of our committee member @jgahan.bsky.social!
Support Ukraine!
February 24, 2025 at 5:09 PM
Support Ukraine!
Beautiful work on dendrite development. www.biorxiv.org/content/10.1...
A dendritic guidance receptor functions in both ligand dependent and independent modes
The formation of an appropriately shaped dendritic arbor is critical for a neuron to receive information. Dendritic morphogenesis is a dynamic process involving growth, branching, and retraction. How ...
www.biorxiv.org
February 13, 2025 at 2:58 PM
Beautiful work on dendrite development. www.biorxiv.org/content/10.1...
Reposted by Fabian Rentzsch
Sea anemones track the suns position?! 🤯 So thrilled to share our paper is finally published in @J_Exp_Biol! 🎉
Congrats to my student leads Eliska Lintnerova and Callum Shawn.
Check it out: journals.biologists.com/jeb/article/...
Congrats to my student leads Eliska Lintnerova and Callum Shawn.
Check it out: journals.biologists.com/jeb/article/...
February 11, 2025 at 5:00 PM
Sea anemones track the suns position?! 🤯 So thrilled to share our paper is finally published in @J_Exp_Biol! 🎉
Congrats to my student leads Eliska Lintnerova and Callum Shawn.
Check it out: journals.biologists.com/jeb/article/...
Congrats to my student leads Eliska Lintnerova and Callum Shawn.
Check it out: journals.biologists.com/jeb/article/...
Reposted by Fabian Rentzsch
My team @naturecomms.bsky.social is looking for a new editor! We need someone to help handle all of the awesome #stemcell and #devbio papers we're getting. DM me if you're interested or have questions about the role or interview process.
springernature.wd3.myworkdayjobs.com/en-US/Spring...
springernature.wd3.myworkdayjobs.com/en-US/Spring...
Associate or Senior Editor, Nature Communications (Stem Cell and Developmental Biology)
Title: Associate or Senior Editor, Nature Communications (Stem Cell and Developmental Biology) Location(s): New York, Jersey City, Philadelphia, Berlin or Heidelberg Application Deadline: About Spring...
springernature.wd3.myworkdayjobs.com
February 3, 2025 at 3:24 PM
My team @naturecomms.bsky.social is looking for a new editor! We need someone to help handle all of the awesome #stemcell and #devbio papers we're getting. DM me if you're interested or have questions about the role or interview process.
springernature.wd3.myworkdayjobs.com/en-US/Spring...
springernature.wd3.myworkdayjobs.com/en-US/Spring...
Reposted by Fabian Rentzsch
Today is International Day of Women & Girls in Science.
Marie Curie, the first woman to win a Nobel Prize. Her contributions have left an indelible mark on the world of science & health & continue to inspire generations of scientists & innovators. 🔬 #WomenInScience #WomenInSTEM
Marie Curie, the first woman to win a Nobel Prize. Her contributions have left an indelible mark on the world of science & health & continue to inspire generations of scientists & innovators. 🔬 #WomenInScience #WomenInSTEM
February 11, 2025 at 7:52 AM
Today is International Day of Women & Girls in Science.
Marie Curie, the first woman to win a Nobel Prize. Her contributions have left an indelible mark on the world of science & health & continue to inspire generations of scientists & innovators. 🔬 #WomenInScience #WomenInSTEM
Marie Curie, the first woman to win a Nobel Prize. Her contributions have left an indelible mark on the world of science & health & continue to inspire generations of scientists & innovators. 🔬 #WomenInScience #WomenInSTEM
Reposted by Fabian Rentzsch
Join us tomorrow for this exciting line up.
🚨ISRB Webinar Alert - Zone 2: Europe, West Asia, Africa to be held 11th February at 4pm Central European Time📷Featuring @stemdevevo.bsky.social (Eve Gazave) and Bill Keyes.
February 10, 2025 at 11:16 PM
Join us tomorrow for this exciting line up.
Reposted by Fabian Rentzsch
The evolution of shape diversity through the lens of physics—explored in our new paper! A fruitful collaboration between our lab @EMBL, Salbreux’s lab @unige & others, led by @BailleulRichar1—now independent at @ENS_ULM—& Nicolas Cuny. bit.ly/3WRqdEa
February 9, 2025 at 12:39 PM
The evolution of shape diversity through the lens of physics—explored in our new paper! A fruitful collaboration between our lab @EMBL, Salbreux’s lab @unige & others, led by @BailleulRichar1—now independent at @ENS_ULM—& Nicolas Cuny. bit.ly/3WRqdEa
Reposted by Fabian Rentzsch
Measuring morphogen transport over multiple spatial scales in live zebrafish embryos https://www.biorxiv.org/content/10.1101/2025.02.06.636788v1
February 9, 2025 at 1:33 AM
Measuring morphogen transport over multiple spatial scales in live zebrafish embryos https://www.biorxiv.org/content/10.1101/2025.02.06.636788v1
Reposted by Fabian Rentzsch
New preprint from the lab on #coral larval light responses, including ciliary arrests and body-wide contractions.
Led by Emelie Brodrick, in collaboration with @micromotility.bsky.social
#biology #cilia @ERC_Research
#hfsp https://www.biorxiv.org/content/10.1101/2025.02.06.636794v1
Led by Emelie Brodrick, in collaboration with @micromotility.bsky.social
#biology #cilia @ERC_Research
#hfsp https://www.biorxiv.org/content/10.1101/2025.02.06.636794v1
February 7, 2025 at 10:25 AM
New preprint from the lab on #coral larval light responses, including ciliary arrests and body-wide contractions.
Led by Emelie Brodrick, in collaboration with @micromotility.bsky.social
#biology #cilia @ERC_Research
#hfsp https://www.biorxiv.org/content/10.1101/2025.02.06.636794v1
Led by Emelie Brodrick, in collaboration with @micromotility.bsky.social
#biology #cilia @ERC_Research
#hfsp https://www.biorxiv.org/content/10.1101/2025.02.06.636794v1
We posted our surprising finding that removal of the nervous system in Nematostella always leads to the regeneration of a second head.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Ectopic head regeneration after nervous system ablation in a sea anemone
Some animals are able to regenerate all missing cell types and large body parts after bisection, a phenomenon called whole-body regeneration. Many of these animals regenerate the correct tissues and s...
www.biorxiv.org
February 5, 2025 at 7:24 AM
We posted our surprising finding that removal of the nervous system in Nematostella always leads to the regeneration of a second head.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Fabian Rentzsch
1/4 🚨 a brand new @biorxiv preprint from the lab! We charcterized both transcriptionally, morphologically and functionally (phagocytosis) immune cells from #Nematostella! We are convinced that our data supports the existence of such specialized cells! www.biorxiv.org/content/10.1...
🧵
🧵
https://biorxiv.org/content/10.110…
January 28, 2025 at 2:09 PM
1/4 🚨 a brand new @biorxiv preprint from the lab! We charcterized both transcriptionally, morphologically and functionally (phagocytosis) immune cells from #Nematostella! We are convinced that our data supports the existence of such specialized cells! www.biorxiv.org/content/10.1...
🧵
🧵
Characterization of the extracellular matrix in Nematostella. www.biorxiv.org/content/10.1...
Molecular dynamics of the matrisome across sea anemone life history
The evolutionary expansion of extracellular matrix (ECM) molecules has been crucial for the establishment of cell adhesion and the transition from unicellular to multicellular life. Members of the pre...
www.biorxiv.org
November 24, 2024 at 12:45 PM
Characterization of the extracellular matrix in Nematostella. www.biorxiv.org/content/10.1...