Elvira Forte
@elviraforte.bsky.social
Scientist passionate about fibrosis, inflammation & single-cell omics technologies. Science writer/advisor helping bridge biology and AI at https://www.ericandwendyschmidtcenter.org/. Consultant at www.lifescienceeditors.com
Former: NatureCVR, jacksonlab
Former: NatureCVR, jacksonlab
Very interesting paper from the Frangogiannis’s lab — #Fibroblast -Specific Loss of #TGF-β Signaling Mediates Lipomatous Metaplasia in the Infarcted #Heart (and cardiac rupture) www.ahajournals.org/doi/10.1161/... @ahajournals.bsky.social @einsteinmededu.bsky.social
Fibroblast-Specific Loss of TGF-β Signaling Mediates Lipomatous Metaplasia in the Infarcted Heart | Circulation
BACKGROUND: In patients surviving myocardial infarction, adipose tissue infiltration within the
scar is a common pathological finding and has been suggested to contribute to dysfunction
and arrhythmog...
www.ahajournals.org
September 20, 2025 at 10:00 PM
Very interesting paper from the Frangogiannis’s lab — #Fibroblast -Specific Loss of #TGF-β Signaling Mediates Lipomatous Metaplasia in the Infarcted #Heart (and cardiac rupture) www.ahajournals.org/doi/10.1161/... @ahajournals.bsky.social @einsteinmededu.bsky.social
Reposted by Elvira Forte
A technology that played a key part in saving millions of lives during the pandemic should be celebrated. Yet in the US, research into mRNA vaccines is being cut. While sadly not unexpected, it’s irresponsible as we argue in our editorial this week 🧪
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Cancelling mRNA studies is the highest irresponsibility
The rest of the world is not following the US government’s dangerous path, and will stick with the technology that helped the world out of the COVID-19 pandemic.
www.nature.com
August 20, 2025 at 10:51 PM
A technology that played a key part in saving millions of lives during the pandemic should be celebrated. Yet in the US, research into mRNA vaccines is being cut. While sadly not unexpected, it’s irresponsible as we argue in our editorial this week 🧪
www.nature.com/articles/d41...
www.nature.com/articles/d41...
🚨 New preprint from the #EricAndWendySchmidtCenter! 🚨
"MORPH Predicts the Single-Cell Outcome of Genetic Perturbations Across Conditions and Data Modalities"
www.biorxiv.org/content/10.1...
@broadinstitute.org #SingleCell #PerturbSeq #OpticalPooledScreen #AIinBiology #ScienceNews #CompBio
"MORPH Predicts the Single-Cell Outcome of Genetic Perturbations Across Conditions and Data Modalities"
www.biorxiv.org/content/10.1...
@broadinstitute.org #SingleCell #PerturbSeq #OpticalPooledScreen #AIinBiology #ScienceNews #CompBio
July 3, 2025 at 3:17 PM
🚨 New preprint from the #EricAndWendySchmidtCenter! 🚨
"MORPH Predicts the Single-Cell Outcome of Genetic Perturbations Across Conditions and Data Modalities"
www.biorxiv.org/content/10.1...
@broadinstitute.org #SingleCell #PerturbSeq #OpticalPooledScreen #AIinBiology #ScienceNews #CompBio
"MORPH Predicts the Single-Cell Outcome of Genetic Perturbations Across Conditions and Data Modalities"
www.biorxiv.org/content/10.1...
@broadinstitute.org #SingleCell #PerturbSeq #OpticalPooledScreen #AIinBiology #ScienceNews #CompBio
June 12, 2025 at 5:10 PM
Reposted by Elvira Forte
This tiny device can shrink dangerous blood clots. It’s called the ‘milli-spinner’ and its invention was partly an accident…
June 10, 2025 at 10:39 AM
This tiny device can shrink dangerous blood clots. It’s called the ‘milli-spinner’ and its invention was partly an accident…
Reposted by Elvira Forte
World Oceans Day is this weekend. 🌊⚒️🧪
🌊 Dive into #WorldOceansDay research. Explore new publications on marine conservation and sustainable oceans at Springer Nature's #SDG14 hub. Visit now and discover more. go.sn.pub/a5jo3v
June 6, 2025 at 1:24 PM
World Oceans Day is this weekend. 🌊⚒️🧪
Reposted by Elvira Forte
Can you go from protein sequence to a generated image of protein localization? New work from the Uhler lab says yes, and it is generalizable to unseen proteins and more than one cell type. I'm excited for work moving us toward virtual cell models.
PUPS - prediction of unseen proteins' subcellular localization - uses machine learning models to predict the localization of unseen proteins in unseen cell lines from sequence and cellular images.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
June 3, 2025 at 7:59 PM
Can you go from protein sequence to a generated image of protein localization? New work from the Uhler lab says yes, and it is generalizable to unseen proteins and more than one cell type. I'm excited for work moving us toward virtual cell models.
Reposted by Elvira Forte
David Liu @harvard.edu beautifully articulates the criticality of basic science funding for developing revolutionary therapeutics like life-saving base editors 👏
youtu.be/8YhJM6zxYDw?...
youtu.be/8YhJM6zxYDw?...
Breakthrough Prize-Winning Biochemist on the Deadly Cost of Funding Cuts | Amanpour and Company
YouTube video by Amanpour and Company
youtu.be
May 24, 2025 at 1:13 AM
David Liu @harvard.edu beautifully articulates the criticality of basic science funding for developing revolutionary therapeutics like life-saving base editors 👏
youtu.be/8YhJM6zxYDw?...
youtu.be/8YhJM6zxYDw?...
Reposted by Elvira Forte
PUPS - prediction of unseen proteins' subcellular localization - uses machine learning models to predict the localization of unseen proteins in unseen cell lines from sequence and cellular images.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
May 13, 2025 at 3:44 PM
PUPS - prediction of unseen proteins' subcellular localization - uses machine learning models to predict the localization of unseen proteins in unseen cell lines from sequence and cellular images.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Elvira Forte
EXPOSED: Never seen before footage reveals the catastrophic impacts caused by bottom trawling ❌
@oceanauk.bsky.social
www.youtube.com/watch?v=IzG9...
@oceanauk.bsky.social
www.youtube.com/watch?v=IzG9...
OCEAN WITH DAVID ATTENBOROUGH | BOTTOM TRAWLING OFFICIAL CLIP | IN CINEMAS NOW | Altitude Films
YouTube video by Altitude Films
www.youtube.com
May 9, 2025 at 8:05 AM
EXPOSED: Never seen before footage reveals the catastrophic impacts caused by bottom trawling ❌
@oceanauk.bsky.social
www.youtube.com/watch?v=IzG9...
@oceanauk.bsky.social
www.youtube.com/watch?v=IzG9...
Reposted by Elvira Forte
Exciting news...Nature Methods is hiring a new editor! This exciting and dynamic role will be shared with the Nature Research Cross-Journal Editorial Team.
Apply here by June 1!
springernature.wd3.myworkdayjobs.com/SpringerNatu...
Apply here by June 1!
springernature.wd3.myworkdayjobs.com/SpringerNatu...
a yellow sign that says we 're hiring
ALT: a yellow sign that says we 're hiring
media.tenor.com
May 9, 2025 at 2:00 PM
Exciting news...Nature Methods is hiring a new editor! This exciting and dynamic role will be shared with the Nature Research Cross-Journal Editorial Team.
Apply here by June 1!
springernature.wd3.myworkdayjobs.com/SpringerNatu...
Apply here by June 1!
springernature.wd3.myworkdayjobs.com/SpringerNatu...
Selective inhibition of stromal mechanosensing suppresses cardiac fibrosis www.nature.com/articles/s41...
Selective inhibition of stromal mechanosensing suppresses cardiac fibrosis - Nature
Inhibition of a cardiac stroma-enriched mechanosensor, SRC—in concert with suppression of the TGFβ pathway—potentiates the reversal of fibroblast activation and alleviates contractile dysfunction in f...
www.nature.com
May 1, 2025 at 10:44 AM
Selective inhibition of stromal mechanosensing suppresses cardiac fibrosis www.nature.com/articles/s41...
Reposted by Elvira Forte
David Liu receives Breakthrough Prize in Life Sciences.
Liu is honored for the development of base editing and prime editing, two gene editing technologies transforming medicine. www.broadinstitute.org/news/david-l...
Liu is honored for the development of base editing and prime editing, two gene editing technologies transforming medicine. www.broadinstitute.org/news/david-l...
David Liu receives Breakthrough Prize in Life Sciences
Liu is honored for the development of base editing and prime editing, two gene editing technologies transforming medicine.
www.broadinstitute.org
April 5, 2025 at 10:43 PM
David Liu receives Breakthrough Prize in Life Sciences.
Liu is honored for the development of base editing and prime editing, two gene editing technologies transforming medicine. www.broadinstitute.org/news/david-l...
Liu is honored for the development of base editing and prime editing, two gene editing technologies transforming medicine. www.broadinstitute.org/news/david-l...
Reposted by Elvira Forte
Thrilled that our work on coronary dominance made the cover of @cellpress.bsky.social! This beautiful image is thanks to the incredible work of @pamrc.bsky.social! 😍
#CardioSky
www.cell.com/cell/fulltex...
#CardioSky
www.cell.com/cell/fulltex...
April 3, 2025 at 4:53 PM
Thrilled that our work on coronary dominance made the cover of @cellpress.bsky.social! This beautiful image is thanks to the incredible work of @pamrc.bsky.social! 😍
#CardioSky
www.cell.com/cell/fulltex...
#CardioSky
www.cell.com/cell/fulltex...
Reposted by Elvira Forte
🌟 Few hours left to submit your abstract for the Annual Meeting of the Society (3-4 July 2025, University of Surrey, Guildford). Great programme, even better people...and a murder mystery at dinner! www.microcirculation.org.uk/75th-annual-... 🌟
75th Annual Meeting of the British Microcirculation and Vascular Biology Society
University of Surrey, GuildfordThursday 3rd and Friday 4th July 2025 Registration Abstract Submission Contact Organising Committee Click below to download flyer BMVBS MembershipMembers (before…
www.microcirculation.org.uk
March 28, 2025 at 1:00 PM
🌟 Few hours left to submit your abstract for the Annual Meeting of the Society (3-4 July 2025, University of Surrey, Guildford). Great programme, even better people...and a murder mystery at dinner! www.microcirculation.org.uk/75th-annual-... 🌟
Reposted by Elvira Forte
This week, I have the privilege of interviewing Dr. Elisabeth Bik (@elisabethbik.bsky.social) in a special two-part series. We discuss her rich professional experience and path to data sleuthing. This is part I .https://www.podbean.com/eas/pb-9p4ye-1865e2f #science #research #integrity #data
Dr. Elisabeth Bik says question the data!-Part I
On this this week's episode, I have the pleasure and privilege of interviewing Dr. Elisabeth Bik in a special two-part series. We discuss her rich professional experience and her path to data sleuthin...
www.podbean.com
March 29, 2025 at 12:37 AM
This week, I have the privilege of interviewing Dr. Elisabeth Bik (@elisabethbik.bsky.social) in a special two-part series. We discuss her rich professional experience and path to data sleuthing. This is part I .https://www.podbean.com/eas/pb-9p4ye-1865e2f #science #research #integrity #data
So many good suggestions in this insightful piece by Dennis J Hazelett. “The only way to give structure to your thoughts is to write them. Writing.Is.Thinking” @naturebiotech.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
An open letter to graduate students and other procrastinators: it’s time to write
Nature Biotechnology - An open letter to graduate students and other procrastinators: it’s time to write
www.nature.com
March 26, 2025 at 11:25 PM
So many good suggestions in this insightful piece by Dennis J Hazelett. “The only way to give structure to your thoughts is to write them. Writing.Is.Thinking” @naturebiotech.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Elvira Forte
Research support for rare diseases, which cumulatively affect ~30 million Americans, is primarily derived from NIH.
Such work is exemplified by Prof Anna Greka @broadinstitute.org in a new Ground Truths podcast.
Open-access, w/ transcript, video, no ads
erictopol.substack.com/p/anna-greka...
Such work is exemplified by Prof Anna Greka @broadinstitute.org in a new Ground Truths podcast.
Open-access, w/ transcript, video, no ads
erictopol.substack.com/p/anna-greka...
Anna Greka: Molecular Sleuthing for Rare Diseases
Listen now | Finding the Mechanisms and the Basis for Potential Cures
erictopol.substack.com
March 9, 2025 at 2:29 PM
Research support for rare diseases, which cumulatively affect ~30 million Americans, is primarily derived from NIH.
Such work is exemplified by Prof Anna Greka @broadinstitute.org in a new Ground Truths podcast.
Open-access, w/ transcript, video, no ads
erictopol.substack.com/p/anna-greka...
Such work is exemplified by Prof Anna Greka @broadinstitute.org in a new Ground Truths podcast.
Open-access, w/ transcript, video, no ads
erictopol.substack.com/p/anna-greka...
Reposted by Elvira Forte
Francis Collins, the NIH Director for 12 years, led the Human Genome Project and other NIH efforts for 32 years, resigned today. Key words from his resignation letter
www.nytimes.com/2025/03/01/u...
www.nytimes.com/2025/03/01/u...
March 1, 2025 at 6:07 PM
Francis Collins, the NIH Director for 12 years, led the Human Genome Project and other NIH efforts for 32 years, resigned today. Key words from his resignation letter
www.nytimes.com/2025/03/01/u...
www.nytimes.com/2025/03/01/u...
I heard about this interesting story a couple of years ago at an AHA meeting @ahascience.bsky.social. It's great to see it published @CellSystems. Congratulations @shovalmiyara.bsky.social, @eldadtzahor.bsky.social
@urialonlab.bsky.social et al!
@urialonlab.bsky.social et al!
It’s finally here! My PhD work, five years in the making, is now published @CellSystems @cellpress.bsky.social 🚨
Cold and hot fibrosis define clinically distinct cardiac pathologies. www.cell.com/cell-systems...
Cold and hot fibrosis define clinically distinct cardiac pathologies. www.cell.com/cell-systems...
Cold and hot fibrosis define clinically distinct cardiac pathologies
Miyara et al. identify two types of fibrosis in cardiac pathologies: “hot fibrosis,”
involving macrophage-myofibroblast interactions in chronic injuries, and acute-injury-driven
“cold fibrosis,” contr...
www.cell.com
February 19, 2025 at 7:24 PM
I heard about this interesting story a couple of years ago at an AHA meeting @ahascience.bsky.social. It's great to see it published @CellSystems. Congratulations @shovalmiyara.bsky.social, @eldadtzahor.bsky.social
@urialonlab.bsky.social et al!
@urialonlab.bsky.social et al!
Reposted by Elvira Forte
Visualizing RNA in live cells using CRISPR
nature.com/articles/s41...
nature.com/articles/s41...
Single-molecule live-cell RNA imaging with CRISPR–Csm - Nature Biotechnology
Single-molecule live-cell fluorescence in situ hybridization uses an RNA-targeting CRISPR–Csm complex to image and track endogenous RNAs.
nature.com
February 18, 2025 at 2:34 PM
Visualizing RNA in live cells using CRISPR
nature.com/articles/s41...
nature.com/articles/s41...
Reposted by Elvira Forte
We started writing/posting Snippets a week ago, and our third one is up now, about tissue clocks and aging, written by Katrina Woolcock with a great image by Gloria Fuentes, both colleagues at Life Science Editors. Have a look!
www.lifescienceeditors.com/2025/02/13/t...
www.lifescienceeditors.com/2025/02/13/t...
Tissue clocks derived from histological signatures of biological aging enable tissue-specific aging predictions from blood - Scientific editing and writing experts - Life Science Editors
Scientific editing and writing experts for manuscripts and grants
www.lifescienceeditors.com
February 14, 2025 at 10:04 PM
We started writing/posting Snippets a week ago, and our third one is up now, about tissue clocks and aging, written by Katrina Woolcock with a great image by Gloria Fuentes, both colleagues at Life Science Editors. Have a look!
www.lifescienceeditors.com/2025/02/13/t...
www.lifescienceeditors.com/2025/02/13/t...
Reposted by Elvira Forte
Checkout "Snippets" - the brainchild of our editor extraordinaire @sfmatheson.bsky.social www.lifescienceeditors.com/snippets/
Snippets - Scientific editing and writing experts - Life Science Editors
"Scientific editing and writing experts for manuscripts and grant
www.lifescienceeditors.com
February 7, 2025 at 5:04 PM
Checkout "Snippets" - the brainchild of our editor extraordinaire @sfmatheson.bsky.social www.lifescienceeditors.com/snippets/
Reposted by Elvira Forte
Doing a little catch-up posting with the Let's Get Coffee series. Today I reflect on my chat with @elviraforte.bsky.social and her thought-provoking question! www.podbean.com/eas/pb-r9pgp...
Let's Get Coffee! Elvira Forte Episode
In this episode of "Let's Get Coffee", I sit back and ponder Elvira's question and read a passage from Ulysses by the 19th Century English poet, Alfred Lord Tennyson. As always, your questions and inp...
www.podbean.com
February 3, 2025 at 2:06 AM
Doing a little catch-up posting with the Let's Get Coffee series. Today I reflect on my chat with @elviraforte.bsky.social and her thought-provoking question! www.podbean.com/eas/pb-r9pgp...
Reposted by Elvira Forte
A total of $12 million in grant funding is available to fund 3 investigators/investigative teams proposing novel uses of Artificial Intelligence to revolutionize cardiovascular and cerebrovascular/brain health and health care delivery.
Learn more: professional.heart.org/en/research-...
Learn more: professional.heart.org/en/research-...
Novel Artificial Intelligence Approaches to Advance Cardiovascular and Cerebrovascular/Brain Health
Research funding opportunity focused on novel AI approaches to advance cardiovascular and cerebrovascular/brain health
professional.heart.org
January 28, 2025 at 11:58 PM
A total of $12 million in grant funding is available to fund 3 investigators/investigative teams proposing novel uses of Artificial Intelligence to revolutionize cardiovascular and cerebrovascular/brain health and health care delivery.
Learn more: professional.heart.org/en/research-...
Learn more: professional.heart.org/en/research-...