Sam Workenhe, DVM, PhD
@deadcellsforlife.bsky.social
Assistant Professor, Immuno-oncology 🎀 Virology🦠
other interests: 🏃🚲 🏋️🛶⛵🍷🍫|
Founder: Viroptosis Immunologics Inc
🇨🇦 🇳🇴 🇪🇹
other interests: 🏃🚲 🏋️🛶⛵🍷🍫|
Founder: Viroptosis Immunologics Inc
🇨🇦 🇳🇴 🇪🇹
Reposted by Sam Workenhe, DVM, PhD
Proud to share our work now out in Cell. We hope what we learned about IgA immune responses to rotavirus can be translated into better vaccines. Congratulations Dr. Kei Haniuda, an amazing PDF. TY
@uoftmedicine.bsky.social
for covering.
temertymedicine.utoronto.ca/news
@uoftmedicine.bsky.social
for covering.
temertymedicine.utoronto.ca/news
Recent News
temertymedicine.utoronto.ca
November 17, 2025 at 11:12 PM
Proud to share our work now out in Cell. We hope what we learned about IgA immune responses to rotavirus can be translated into better vaccines. Congratulations Dr. Kei Haniuda, an amazing PDF. TY
@uoftmedicine.bsky.social
for covering.
temertymedicine.utoronto.ca/news
@uoftmedicine.bsky.social
for covering.
temertymedicine.utoronto.ca/news
Reposted by Sam Workenhe, DVM, PhD
This week is particularly remarkable in terms of #CellDeath and infection biology-related discoveries: biomed.news/bims-cediti/...
Highlight 1: SIGLEC12 mediates plasma membrane rupture during necroptotic cell death:
Highlight 1: SIGLEC12 mediates plasma membrane rupture during necroptotic cell death:
SIGLEC12 mediates plasma membrane rupture during necroptotic cell death - Nature
CRISPR–Cas9-based genome-wide screening shows that SIGLEC12 mediates plasma membrane rupture in cells undergoing necroptosis, possibly through a human-specific mechanism, indicating its potential as a...
www.nature.com
November 16, 2025 at 9:09 AM
This week is particularly remarkable in terms of #CellDeath and infection biology-related discoveries: biomed.news/bims-cediti/...
Highlight 1: SIGLEC12 mediates plasma membrane rupture during necroptotic cell death:
Highlight 1: SIGLEC12 mediates plasma membrane rupture during necroptotic cell death:
Reposted by Sam Workenhe, DVM, PhD
Fascinating as always @reisesousalab.bsky.social &co! 1 aminoacid makes the difference between a CLR that drives cross-presentation or immune activation!! Kudos to all authors of this cool paper! 👇👇👇
Delighted that this study is finally out @embojournal.org. A detailed analysis of how DNGR-1/CLEC9A signals to promote cross-presentation of dead cell-associated antigens yet does not activate dendritic cells.
www.embopress.org/doi/full/10....
www.embopress.org/doi/full/10....
DNGR-1 signalling limits dendritic cell activation for optimal antigen cross-presentation | The EMBO Journal
imageimageDNGR-1 (CLEC9A) is a C-type lectin receptor of type-1 conventional dendritic cells (cDC1s) with an important role in cross-presentation of dead cell antigens. This study explores how it equips cDC1s with the ability to cross-present such ...
www.embopress.org
November 3, 2025 at 10:45 PM
Fascinating as always @reisesousalab.bsky.social &co! 1 aminoacid makes the difference between a CLR that drives cross-presentation or immune activation!! Kudos to all authors of this cool paper! 👇👇👇
Reposted by Sam Workenhe, DVM, PhD
🚨Job posting! #UMassAmherst Department of Veterinary and Animal Sciences is hiring a TT faculty member in #Immunology. Both fundamental and translational areas considered. Please spread the word!
careers.umass.edu/amherst/en-u...
careers.umass.edu/amherst/en-u...
Details - Assistant Professor - Immunology | Human Resources | UMass Amherst
careers.umass.edu
October 15, 2025 at 9:07 PM
🚨Job posting! #UMassAmherst Department of Veterinary and Animal Sciences is hiring a TT faculty member in #Immunology. Both fundamental and translational areas considered. Please spread the word!
careers.umass.edu/amherst/en-u...
careers.umass.edu/amherst/en-u...
Reposted by Sam Workenhe, DVM, PhD
Are you a recent PhD interested in a postdoc in Canada? Up to 20% of NSERC Postdoc Fellowships (70k/y for 2y) will be awarded to International applicants, who did their PhD outside of Canada. Deadline is 17 October. See: www.nserc-crsng.gc.ca/Students-Etu...
NSERC - Canada Postdoctoral Research Award program
NSERC - Canada Postdoctoral Research Award program
www.nserc-crsng.gc.ca
September 20, 2025 at 6:26 AM
Are you a recent PhD interested in a postdoc in Canada? Up to 20% of NSERC Postdoc Fellowships (70k/y for 2y) will be awarded to International applicants, who did their PhD outside of Canada. Deadline is 17 October. See: www.nserc-crsng.gc.ca/Students-Etu...
Reposted by Sam Workenhe, DVM, PhD
Hey Toronto! It's 1 week until the #TorontoFringe and the first performance of "The Perils of Being Born in the Fall" on July 2nd. Tickets are as low as $4 for a full hour of 'edu-tainment' by your friendly neighbourhood scientist. Details & tickets at this link..
fringetoronto.com/fringe/show/...
fringetoronto.com/fringe/show/...
The Perils of Being Born in the Fall at the Toronto Fringe 2025
YouTube video by Dawn Bowdish
youtu.be
June 25, 2025 at 9:53 PM
Hey Toronto! It's 1 week until the #TorontoFringe and the first performance of "The Perils of Being Born in the Fall" on July 2nd. Tickets are as low as $4 for a full hour of 'edu-tainment' by your friendly neighbourhood scientist. Details & tickets at this link..
fringetoronto.com/fringe/show/...
fringetoronto.com/fringe/show/...
Reposted by Sam Workenhe, DVM, PhD
Reposted by Sam Workenhe, DVM, PhD
The loss of TBK1, or both TBK1 and the related kinase IKKε, results in uncontrolled cell death–driven inflammation. We show that TBK1/IKKε prevent premature cell death by limiting the activity of multiple death pathways in myeloid cells. www.science.org/doi/10.1126/...
TBK1 and IKKε prevent premature cell death by limiting the activity of both RIPK1 and NLRP3 death pathways
TBK1 and IKKe prevent premature cell death by limiting the activity of multiple death pathways in myeloid cells.
www.science.org
March 7, 2025 at 8:49 PM
The loss of TBK1, or both TBK1 and the related kinase IKKε, results in uncontrolled cell death–driven inflammation. We show that TBK1/IKKε prevent premature cell death by limiting the activity of multiple death pathways in myeloid cells. www.science.org/doi/10.1126/...
Reposted by Sam Workenhe, DVM, PhD
Reposted by Sam Workenhe, DVM, PhD
Do you know (or are you) a senior scientist in the USA who might like to move to Canada in the near future? The 2026 call for CERCs (Canada Excellence Research Chairs) was posted last month: 🧪 ⚛️ 🔭 🇨🇦
Canada Excellence Research Chairs - Home
The CERC Program offers eligible Canadian degree-granting universities the opportunity to establish research Chairs at their institutions in research areas that are of strategic importance to Canada.
www.cerc.gc.ca
February 25, 2025 at 8:30 PM
Do you know (or are you) a senior scientist in the USA who might like to move to Canada in the near future? The 2026 call for CERCs (Canada Excellence Research Chairs) was posted last month: 🧪 ⚛️ 🔭 🇨🇦
Reposted by Sam Workenhe, DVM, PhD
I joined 75+ @nobelprize.bsky.social laureates urging US Senators to oppose RFK Jr.'s confirmation as DHHS Secretary. If you’re in a state with GOP senators, PLEASE reach out to them! I’d deeply appreciate it if you amplified this post! 🙏
www.nytimes.com/2024/12/09/h...
www.nytimes.com/2024/12/09/h...
December 9, 2024 at 11:19 PM
I joined 75+ @nobelprize.bsky.social laureates urging US Senators to oppose RFK Jr.'s confirmation as DHHS Secretary. If you’re in a state with GOP senators, PLEASE reach out to them! I’d deeply appreciate it if you amplified this post! 🙏
www.nytimes.com/2024/12/09/h...
www.nytimes.com/2024/12/09/h...
Reposted by Sam Workenhe, DVM, PhD
Every panel i ever participated in
December 4, 2024 at 7:48 PM
Every panel i ever participated in
Reposted by Sam Workenhe, DVM, PhD
C. elegans neuroscientist in a neuroscience startup pack
November 20, 2024 at 6:47 PM
C. elegans neuroscientist in a neuroscience startup pack