Ragnar {Groot Koerkamp}
@curiouscoding.nl
Postdoc on high troughput bioinformatics @ KIT Karlsruhe;
IMO, ICPC, Xoogler, Rust, road-cycling, hiking, wild camping, photography
IMO, ICPC, Xoogler, Rust, road-cycling, hiking, wild camping, photography
vibe coding is the new doom scrolling?
Weekend thoughts on Gas Town, Beads, slop AI browsers, and AI-generated PRs flooding overwhelmed maintainers. I don't think we're ready for our new powers we're wielding. lucumr.pocoo.org/2026/1/18/ag...
Agent Psychosis: Are We Going Insane?
What’s going on with the AI builder community right now?
lucumr.pocoo.org
January 19, 2026 at 12:51 AM
vibe coding is the new doom scrolling?
Just came across the 2021 Turing Lecture. Has a lot of nice observations regarding the increasing gap between compute and memory bandwidth. It advocates "communication avoiding" algorithms and notes how algorithms can only be future proof if they scale with threads.
dl.acm.org/doi/10.1145/...
dl.acm.org/doi/10.1145/...
The evolution of mathematical software | Communications of the ACM
Tracing how software and algorithms follow the hardware.
dl.acm.org
January 18, 2026 at 11:10 PM
Just came across the 2021 Turing Lecture. Has a lot of nice observations regarding the increasing gap between compute and memory bandwidth. It advocates "communication avoiding" algorithms and notes how algorithms can only be future proof if they scale with threads.
dl.acm.org/doi/10.1145/...
dl.acm.org/doi/10.1145/...
How are your algorithm's KPIs doing?
January 18, 2026 at 9:38 PM
How are your algorithm's KPIs doing?
Reposted by Ragnar {Groot Koerkamp}
If yes, “hand written code” will be a status signifier in the same way hand sewn buttonholes are in tailoring
January 18, 2026 at 12:17 AM
If yes, “hand written code” will be a status signifier in the same way hand sewn buttonholes are in tailoring
If I see one more "Subsection title (for real)"...
January 15, 2026 at 8:00 AM
If I see one more "Subsection title (for real)"...
Guess how many citations the original FM-index paper has. Then look it up.
January 14, 2026 at 8:51 PM
Guess how many citations the original FM-index paper has. Then look it up.
Reposted by Ragnar {Groot Koerkamp}
I am looking for a postdoc to develop high-performance algorithms in computational genomics. Email or DM me if interested. For more information, see hlilab.github.io/vacancies. RTs appreciated!
HLi Lab - Vacancies
Openings
hlilab.github.io
January 14, 2026 at 3:44 PM
I am looking for a postdoc to develop high-performance algorithms in computational genomics. Email or DM me if interested. For more information, see hlilab.github.io/vacancies. RTs appreciated!
Reposted by Ragnar {Groot Koerkamp}
Why is it that, despite being behind a perpetual cloud flare fence, @biorxivpreprint.bsky.social feels like it’s down an awful lot?
January 14, 2026 at 3:01 PM
Why is it that, despite being behind a perpetual cloud flare fence, @biorxivpreprint.bsky.social feels like it’s down an awful lot?
Reposted by Ragnar {Groot Koerkamp}
HTML preview & export now available in the web app! With HTML export, you can create a website from the same Typst file as your PDFs. This makes it easy to create documents that feel just as at home on the web as they do in print.
January 13, 2026 at 6:21 PM
HTML preview & export now available in the web app! With HTML export, you can create a website from the same Typst file as your PDFs. This makes it easy to create documents that feel just as at home on the web as they do in print.
Guess my blog having a CC license is a good thing 🫤
January 12, 2026 at 10:06 PM
Guess my blog having a CC license is a good thing 🫤
Yes please!
All Git repository tool configuration files (CI, issue template, etc.) should go in to `.config` like Cargo Nextest: nexte.st/docs/configu...
Currently we have .gitlab, .config, .cargo, ..., and it creates clutter.
Currently we have .gitlab, .config, .cargo, ..., and it creates clutter.
Configuring nextest - cargo-nextest
Configuring nextest: information about profiles and hierarchical configuration.
nexte.st
January 12, 2026 at 9:58 PM
Yes please!
Reposted by Ragnar {Groot Koerkamp}
God help me I’ve actually started working on this
So the starting point is JSON but with Python aesthetics: indentations and newline-oriented syntax, but {} and [] still permissible. true/false the only booleans, of course.
I’d immediately get rid of the “documents” thing and anchors and many of the strings.
I’d immediately get rid of the “documents” thing and anchors and many of the strings.
January 12, 2026 at 8:46 PM
God help me I’ve actually started working on this
Reposted by Ragnar {Groot Koerkamp}
Minister Van Weel heeft bijna genoeg informatie verzameld om Holocaust te kunnen veroordelen
Minister Van Weel heeft bijna genoeg informatie verzameld om Holocaust te kunnen veroordelen
Hij werd er vandaag weer naar gevraagd: bent u ertoe bereid zich uit te spreken over de rol van Nazi-Duitsland in de Holocaust?
speld.nl
January 12, 2026 at 5:02 PM
Minister Van Weel heeft bijna genoeg informatie verzameld om Holocaust te kunnen veroordelen
Grew up 100m from the Waal, offspring of the Rhine. Biked a bridge across it to highschool for 6 years.
Then a year at 100m off the Thames, continued by 8 years on a tributary of the Rhine.
Now moving to mid-Rhine, but sadly 5km away from it.
So yeah, I'm a Rhine boy :)
Then a year at 100m off the Thames, continued by 8 years on a tributary of the Rhine.
Now moving to mid-Rhine, but sadly 5km away from it.
So yeah, I'm a Rhine boy :)
My favorite Twitter prompt was "RT this with your home river," so reskeet this with your home river.
Mine is the Patuxent.
Mine is the Patuxent.
January 12, 2026 at 9:43 PM
Grew up 100m from the Waal, offspring of the Rhine. Biked a bridge across it to highschool for 6 years.
Then a year at 100m off the Thames, continued by 8 years on a tributary of the Rhine.
Now moving to mid-Rhine, but sadly 5km away from it.
So yeah, I'm a Rhine boy :)
Then a year at 100m off the Thames, continued by 8 years on a tributary of the Rhine.
Now moving to mid-Rhine, but sadly 5km away from it.
So yeah, I'm a Rhine boy :)
Reposted by Ragnar {Groot Koerkamp}
Reposted by Ragnar {Groot Koerkamp}
🚀 Our new paper on Alignoth just published in Bioinformatics!
Alignoth generates self-contained interactive HTML read alignment plots from BAM files – Rust-based, portable, and ideal for headless workflows.
📄 doi.org/10.1093/bioi...
#bioinformatics #genomics #rust @johanneskoester.bsky.social
Alignoth generates self-contained interactive HTML read alignment plots from BAM files – Rust-based, portable, and ideal for headless workflows.
📄 doi.org/10.1093/bioi...
#bioinformatics #genomics #rust @johanneskoester.bsky.social
January 8, 2026 at 1:57 PM
🚀 Our new paper on Alignoth just published in Bioinformatics!
Alignoth generates self-contained interactive HTML read alignment plots from BAM files – Rust-based, portable, and ideal for headless workflows.
📄 doi.org/10.1093/bioi...
#bioinformatics #genomics #rust @johanneskoester.bsky.social
Alignoth generates self-contained interactive HTML read alignment plots from BAM files – Rust-based, portable, and ideal for headless workflows.
📄 doi.org/10.1093/bioi...
#bioinformatics #genomics #rust @johanneskoester.bsky.social
Reposted by Ragnar {Groot Koerkamp}
Reposted by Ragnar {Groot Koerkamp}
This. Also: Europe does not do visionary speeches the way the Americans do. Our public sphere works in fundamentally different ways. Just because we don't do change like you do doesn't mean we do not do change. Brexiteers got this wrong too.
The thing I think folks struggle to appreciate with this stuff tho is however hard it is to wean Europe off US tech is *at least as hard* as it will be for US tech to get back into Europe after that type of transition kicks into high gear
January 11, 2026 at 2:51 PM
This. Also: Europe does not do visionary speeches the way the Americans do. Our public sphere works in fundamentally different ways. Just because we don't do change like you do doesn't mean we do not do change. Brexiteers got this wrong too.
Reposted by Ragnar {Groot Koerkamp}
Yet, for e.g., n = 2^30 bits, the o(n) extra space is 6.67% +
60% + 0.18% = 66.85% of n, which is not so negligible.
- Gonzales, Grabowski, Makinen, Navarro
60% + 0.18% = 66.85% of n, which is not so negligible.
- Gonzales, Grabowski, Makinen, Navarro
January 10, 2026 at 5:04 PM
Yet, for e.g., n = 2^30 bits, the o(n) extra space is 6.67% +
60% + 0.18% = 66.85% of n, which is not so negligible.
- Gonzales, Grabowski, Makinen, Navarro
60% + 0.18% = 66.85% of n, which is not so negligible.
- Gonzales, Grabowski, Makinen, Navarro
When will the submission deadline for recomb-seq proceedings be?
@recombseq.bsky.social @pashadag.bsky.social @ksahlin.bsky.social
@recombseq.bsky.social @pashadag.bsky.social @ksahlin.bsky.social
January 10, 2026 at 3:00 PM
When will the submission deadline for recomb-seq proceedings be?
@recombseq.bsky.social @pashadag.bsky.social @ksahlin.bsky.social
@recombseq.bsky.social @pashadag.bsky.social @ksahlin.bsky.social
What's it called when you subtweet but it's the first sentence of a paper?
(The footnote goes to Rank9 and Dijkstra)
(The footnote goes to Rank9 and Dijkstra)
January 10, 2026 at 2:22 PM
What's it called when you subtweet but it's the first sentence of a paper?
(The footnote goes to Rank9 and Dijkstra)
(The footnote goes to Rank9 and Dijkstra)
What's your longest Oauth2 login chain?
January 10, 2026 at 1:45 AM
What's your longest Oauth2 login chain?
Reposted by Ragnar {Groot Koerkamp}
today in "cross-language RPC": Rust and Swift have a different bit pattern for pi
January 9, 2026 at 3:07 PM
today in "cross-language RPC": Rust and Swift have a different bit pattern for pi
Reposted by Ragnar {Groot Koerkamp}
This is the official GPS status website with an *animated* banner for an urgent advisory about GPS moving to a different control center. gwcc-ws.cce.af.mil/gpsoc/
January 9, 2026 at 11:16 AM
This is the official GPS status website with an *animated* banner for an urgent advisory about GPS moving to a different control center. gwcc-ws.cce.af.mil/gpsoc/