Conor (Conchúr) Meehan
@conmeehan.bsky.social
Researching WGS/Epi/Taxonomy of pathogenic mycobacteria and evo of microbiomes. Irish-born, Nottingham-working. Call me Conchúr if you can pronounce it. He/They
https://www.ntu.ac.uk/staff-profiles/science-technology/conor-meehan
https://www.ntu.ac.uk/staff-profiles/science-technology/conor-meehan
Reposted by Conor (Conchúr) Meehan
Congratulations to our poster prize winners at @bsacandjac.bsky.social #AntibioticResistance & Mechanisms meeting 🎉 #MicroSky
November 28, 2025 at 8:43 PM
Congratulations to our poster prize winners at @bsacandjac.bsky.social #AntibioticResistance & Mechanisms meeting 🎉 #MicroSky
Reposted by Conor (Conchúr) Meehan
I had a great time at the @bsacandjac.bsky.social ARM workshop! I met some wonderful scientists and had great discussions about my work! Also, I walked away with a poster prize!! Thanks for organising @friendlymicrobe.bsky.social @conmeehan.bsky.social
November 28, 2025 at 3:54 PM
I had a great time at the @bsacandjac.bsky.social ARM workshop! I met some wonderful scientists and had great discussions about my work! Also, I walked away with a poster prize!! Thanks for organising @friendlymicrobe.bsky.social @conmeehan.bsky.social
Reposted by Conor (Conchúr) Meehan
Ending @bsacandjac.bsky.social #AntibioticResistance & Mechanisms with @astridpm.bsky.social talking about GARDP's work to advance antimicrobial R&D through their REVIVE programme. They have superb resources & webinars, linking academic/clinical/industry stakeholders revive.gardp.org #MicroSky
Home
Welcome to REVIVE!
For many years, antimicrobial researchers left the field or re-focused their activities risking losing invaluable experience and knowledge crucial for the discovery, research and de...
revive.gardp.org
November 28, 2025 at 12:38 PM
Ending @bsacandjac.bsky.social #AntibioticResistance & Mechanisms with @astridpm.bsky.social talking about GARDP's work to advance antimicrobial R&D through their REVIVE programme. They have superb resources & webinars, linking academic/clinical/industry stakeholders revive.gardp.org #MicroSky
Reposted by Conor (Conchúr) Meehan
Participate in the EUP OHAMR survey to strengthen AMR research capacity #AntibioticResistance #MicroSky ohamr.eu/2025/11/18/o...
Participate in the EUP OHAMR survey to strengthen AMR research capacity! - EUP OHAMR
We are launching a survey to identify gaps in strengthening research capacity in the field of AMR. Your input is valuable!
ohamr.eu
November 28, 2025 at 12:54 PM
Participate in the EUP OHAMR survey to strengthen AMR research capacity #AntibioticResistance #MicroSky ohamr.eu/2025/11/18/o...
Reposted by Conor (Conchúr) Meehan
Now at @bsacandjac.bsky.social #AntibioticResistance & Mechanisms:
@reepkpd333.bsky.social is telling us how her hospital PK/PD lab is exploring suitable models to evaluate #phage + abx combinations scholar.google.com/citations?us... #MicroSky
@reepkpd333.bsky.social is telling us how her hospital PK/PD lab is exploring suitable models to evaluate #phage + abx combinations scholar.google.com/citations?us... #MicroSky
November 28, 2025 at 12:22 PM
Now at @bsacandjac.bsky.social #AntibioticResistance & Mechanisms:
@reepkpd333.bsky.social is telling us how her hospital PK/PD lab is exploring suitable models to evaluate #phage + abx combinations scholar.google.com/citations?us... #MicroSky
@reepkpd333.bsky.social is telling us how her hospital PK/PD lab is exploring suitable models to evaluate #phage + abx combinations scholar.google.com/citations?us... #MicroSky
Reposted by Conor (Conchúr) Meehan
More evolution at @bsacandjac.bsky.social #AntibioticResistance & mechanisms: @dralhubb.bsky.social exploring how order of antibiotic cycling affects selection, incl. for collateral resistance/susceptibility: order may affect specific mutations selected scholar.google.com/citations?us... #MicroSky
scholar.google.com
November 28, 2025 at 12:05 PM
More evolution at @bsacandjac.bsky.social #AntibioticResistance & mechanisms: @dralhubb.bsky.social exploring how order of antibiotic cycling affects selection, incl. for collateral resistance/susceptibility: order may affect specific mutations selected scholar.google.com/citations?us... #MicroSky
Reposted by Conor (Conchúr) Meehan
Evolution at @bsacandjac.bsky.social
#AntibioticResistance & Mechanisms: @dannagifford.bsky.social found E. coli mutator genotypes don't just increase probability of resistance evolution, they increase probability of aa substitution vs. frameshift/indel - lower costs? dannagifford.com #MicroSky
#AntibioticResistance & Mechanisms: @dannagifford.bsky.social found E. coli mutator genotypes don't just increase probability of resistance evolution, they increase probability of aa substitution vs. frameshift/indel - lower costs? dannagifford.com #MicroSky
Danna Gifford
School of Biological Sciences | Faculty of Biology Medicine and Health | University of Manchester
dannagifford.com
November 28, 2025 at 11:45 AM
Evolution at @bsacandjac.bsky.social
#AntibioticResistance & Mechanisms: @dannagifford.bsky.social found E. coli mutator genotypes don't just increase probability of resistance evolution, they increase probability of aa substitution vs. frameshift/indel - lower costs? dannagifford.com #MicroSky
#AntibioticResistance & Mechanisms: @dannagifford.bsky.social found E. coli mutator genotypes don't just increase probability of resistance evolution, they increase probability of aa substitution vs. frameshift/indel - lower costs? dannagifford.com #MicroSky
Reposted by Conor (Conchúr) Meehan
Now at @bsacandjac.bsky.social #AntibioticResistance & Mechanisms, @cgmargarida.bsky.social is showing us how she uses zebrafish to find ways to induce trained immunity against respiratory pathogens - a high throughput model with key homology with humans warwick.ac.uk/fac/sci/life... #MicroSky
Dr Margarida Castro Gomes Spencer
warwick.ac.uk
November 28, 2025 at 10:03 AM
Now at @bsacandjac.bsky.social #AntibioticResistance & Mechanisms, @cgmargarida.bsky.social is showing us how she uses zebrafish to find ways to induce trained immunity against respiratory pathogens - a high throughput model with key homology with humans warwick.ac.uk/fac/sci/life... #MicroSky
Reposted by Conor (Conchúr) Meehan
90% of infections begin in the mucosa, but most vaccines are intravenous - so don't activate mucosal immunity. At @bsacandjac.bsky.social #AntibioticResistance & mechanisms, Ruth Griffin is showing her work developing mucosal vaccine delivery strategies www.nottingham.ac.uk/life-science... #MicroSky
People - The University of Nottingham
www.nottingham.ac.uk
November 28, 2025 at 9:44 AM
90% of infections begin in the mucosa, but most vaccines are intravenous - so don't activate mucosal immunity. At @bsacandjac.bsky.social #AntibioticResistance & mechanisms, Ruth Griffin is showing her work developing mucosal vaccine delivery strategies www.nottingham.ac.uk/life-science... #MicroSky
Reposted by Conor (Conchúr) Meehan
Something totally new to me at @bsacandjac.bsky.social
#AntibioticResistance & mechanisms: Kendle Maslowski shows that attenuated Salmonella Typhimurium can infect tumours and kill cancer cells via metabolic competition www.embopress.org/doi/full/10.... #MicroSky
#AntibioticResistance & mechanisms: Kendle Maslowski shows that attenuated Salmonella Typhimurium can infect tumours and kill cancer cells via metabolic competition www.embopress.org/doi/full/10.... #MicroSky
Salmonella cancer therapy metabolically disrupts tumours at the collateral cost of T cell immunity | EMBO Molecular Medicine
imageimageAttenuated Salmonella show promise as cancer therapeutics, yet T cells play no role
in efficacy, limiting combined checkpoint blockade therapies or induction of immune
memory. Improving T ce...
www.embopress.org
November 28, 2025 at 9:19 AM
Something totally new to me at @bsacandjac.bsky.social
#AntibioticResistance & mechanisms: Kendle Maslowski shows that attenuated Salmonella Typhimurium can infect tumours and kill cancer cells via metabolic competition www.embopress.org/doi/full/10.... #MicroSky
#AntibioticResistance & mechanisms: Kendle Maslowski shows that attenuated Salmonella Typhimurium can infect tumours and kill cancer cells via metabolic competition www.embopress.org/doi/full/10.... #MicroSky
Reposted by Conor (Conchúr) Meehan
'Bacterial dietitian' @danybeste.bsky.social is telling @bsacandjac.bsky.social #AntibioticResistance & mechanisms workshop how switching C sources affects Tb antibiotic tolerance - can we use this info to design adjuvants that increase sensitivity? www.surrey.ac.uk/people/dany-... #MicroSky
Dr Dany Beste | University of Surrey
https://www.surrey.ac.uk/people/dany-beste#research#MicroSky
November 27, 2025 at 5:00 PM
'Bacterial dietitian' @danybeste.bsky.social is telling @bsacandjac.bsky.social #AntibioticResistance & mechanisms workshop how switching C sources affects Tb antibiotic tolerance - can we use this info to design adjuvants that increase sensitivity? www.surrey.ac.uk/people/dany-... #MicroSky
Reposted by Conor (Conchúr) Meehan
Flash talk 4 @bsacandjac.bsky.social #AntibioticResistance & mechanisms! Caleb Marsh is designing dual efflux inhibitor-abx molecules, then testing them in @ukhsa.bsky.social's open innovation platform for abx development. Very promising drops in MIC & spontaneous resistance rates. #MicroSky
November 27, 2025 at 5:55 PM
Flash talk 4 @bsacandjac.bsky.social #AntibioticResistance & mechanisms! Caleb Marsh is designing dual efflux inhibitor-abx molecules, then testing them in @ukhsa.bsky.social's open innovation platform for abx development. Very promising drops in MIC & spontaneous resistance rates. #MicroSky
Reposted by Conor (Conchúr) Meehan
Flash talk 3 @bsacandjac.bsky.social #AntibioticResistance & mechanisms! @mwilde.bsky.social on AMR gene silencing via mutation & reversion: engineering in SNP in a carbapenemase alters AST profile, but effect depends on genetic background. #MicroSky
November 27, 2025 at 5:46 PM
Flash talk 3 @bsacandjac.bsky.social #AntibioticResistance & mechanisms! @mwilde.bsky.social on AMR gene silencing via mutation & reversion: engineering in SNP in a carbapenemase alters AST profile, but effect depends on genetic background. #MicroSky
Reposted by Conor (Conchúr) Meehan
Flash talk 2 @bsacandjac.bsky.social #AntibioticResistance & mechanisms! @taylorwr.bsky.social found that E. coli damaged but not killed by b-lactams die when they try to divide on abx-free solid medium, but not in liquid - so do plate count assays overestimate b-lactam killing? #MicroSky
November 27, 2025 at 5:31 PM
Flash talk 2 @bsacandjac.bsky.social #AntibioticResistance & mechanisms! @taylorwr.bsky.social found that E. coli damaged but not killed by b-lactams die when they try to divide on abx-free solid medium, but not in liquid - so do plate count assays overestimate b-lactam killing? #MicroSky
Reposted by Conor (Conchúr) Meehan
Flash talk 1 @bsacandjac.bsky.social #AntibioticResistance & mechanisms! Ahmed Alomar selected E. coli for colistin resistance: clinical isolates evolved higher MIC than MG1655, associated with mutations in pmrA/B, many of those in pmrA not previously described. @imibirmingham.bsky.social #MicroSky
November 27, 2025 at 5:18 PM
Flash talk 1 @bsacandjac.bsky.social #AntibioticResistance & mechanisms! Ahmed Alomar selected E. coli for colistin resistance: clinical isolates evolved higher MIC than MG1655, associated with mutations in pmrA/B, many of those in pmrA not previously described. @imibirmingham.bsky.social #MicroSky
Reposted by Conor (Conchúr) Meehan
Synthetic teixobactin development: Ishwar Singh is telling @bsacandjac.bsky.social #antibioticResistance & mechanisms meeting about the long and winding road to promising new molecules with good bioactivity www.liverpool.ac.uk/people/ishwa... #MicroSky
Dr Ishwar Singh | Our people | University of Liverpool
www.liverpool.ac.uk
November 27, 2025 at 4:42 PM
Synthetic teixobactin development: Ishwar Singh is telling @bsacandjac.bsky.social #antibioticResistance & mechanisms meeting about the long and winding road to promising new molecules with good bioactivity www.liverpool.ac.uk/people/ishwa... #MicroSky
Reposted by Conor (Conchúr) Meehan
Now at @bsacandjac.bsky.social, @sykhalid.bsky.social explains that, while the outer leaflet of the Gram- OM is a calm sea anchored by OmpA to the cell wall, the phospholipids of the inner leaflet are paddling about madly beneath the surface. #MicroSky khalidlab.web.ox.ac.uk/publications
Publications
khalidlab.web.ox.ac.uk
November 27, 2025 at 4:20 PM
Now at @bsacandjac.bsky.social, @sykhalid.bsky.social explains that, while the outer leaflet of the Gram- OM is a calm sea anchored by OmpA to the cell wall, the phospholipids of the inner leaflet are paddling about madly beneath the surface. #MicroSky khalidlab.web.ox.ac.uk/publications
Reposted by Conor (Conchúr) Meehan
What drives the acquisition and loss of #AntibioticResistance in Salmonella? @flashton.bsky.social kicking off the @bsacandjac.bsky.social resistance & mechanisms meeting, talking about pathogen genomic surveillance around the world, particularly in Africa www.psi.ox.ac.uk/our-team/phi... #MicroSky
Philip Ashton
Philip Ashton
www.psi.ox.ac.uk
November 27, 2025 at 2:02 PM
What drives the acquisition and loss of #AntibioticResistance in Salmonella? @flashton.bsky.social kicking off the @bsacandjac.bsky.social resistance & mechanisms meeting, talking about pathogen genomic surveillance around the world, particularly in Africa www.psi.ox.ac.uk/our-team/phi... #MicroSky
Reposted by Conor (Conchúr) Meehan
Next at @bsacandjac.bsky.social #AntibioticResistance & mechanisms, @jodywinter.bsky.social is explaining how a partnership between academics, clinicians & health workers in Nottingham & Makerere is is sharing best practice in stewardship between UK & Uganda jodywinter.wixsite.com/waaw/cop #MicroSky
COP | Waaw
jodywinter.wixsite.com
November 27, 2025 at 2:36 PM
Next at @bsacandjac.bsky.social #AntibioticResistance & mechanisms, @jodywinter.bsky.social is explaining how a partnership between academics, clinicians & health workers in Nottingham & Makerere is is sharing best practice in stewardship between UK & Uganda jodywinter.wixsite.com/waaw/cop #MicroSky
Reposted by Conor (Conchúr) Meehan
Now at @bsacandjac.bsky.social #AntibioticResistance & mechanisms workshop, Kirsty Sands @ineosoxford.bsky.social stresses the dominance of Kleb pneumoniae in neonatal sepsis, and how the work she leads is quantifying the impact of AMR on neonatal sepsis in LMICs: www.ineosoxford.ox.ac.uk/barnards
BARNARDS
Causes and impacts of sepsis in new-born babies
www.ineosoxford.ox.ac.uk
November 27, 2025 at 3:18 PM
Now at @bsacandjac.bsky.social #AntibioticResistance & mechanisms workshop, Kirsty Sands @ineosoxford.bsky.social stresses the dominance of Kleb pneumoniae in neonatal sepsis, and how the work she leads is quantifying the impact of AMR on neonatal sepsis in LMICs: www.ineosoxford.ox.ac.uk/barnards
Reposted by Conor (Conchúr) Meehan
Apart from the AI junk part… the notion that one should not offer a potential mechanistic explanation for an observation, without first spending years & (unavailable) $$ trying to test possibilities before sharing the observation with others (who may be better equipped to investigate the mechanism)…
Nature suggests you use their "Manuscript Adviser" bot to get advice before submitting
I uploaded the classic Watson & Crick paper about DNA structure, and the Adviser had this to say about one of the greatest paper endings of the century:
I uploaded the classic Watson & Crick paper about DNA structure, and the Adviser had this to say about one of the greatest paper endings of the century:
November 3, 2025 at 10:37 PM
Apart from the AI junk part… the notion that one should not offer a potential mechanistic explanation for an observation, without first spending years & (unavailable) $$ trying to test possibilities before sharing the observation with others (who may be better equipped to investigate the mechanism)…
Reposted by Conor (Conchúr) Meehan
If you’re interested in metals, microbes and maths 🤘 - please check out this PhD on the impact of metals on microbial communities with @thecopperdoctor.bsky.social @blindmath.bsky.social Denis Patterson and myself, you’d be based in Durham & be part of a vibrant interdisciplinary research group
We're advertising a PhD at the intersection of mathematical ecology, metallobiology, and microbiology to study the impact of metals on microbial communities with @thecopperdoctor.bsky.social @kateduncan.bsky.social and Denis Patterson. Come join us in lovely Durham!
iapetus.ac.uk/studentships...
iapetus.ac.uk/studentships...
When nutrients turn toxic: how metals shape microbial coexistence
iapetus.ac.uk
October 29, 2025 at 2:49 PM
If you’re interested in metals, microbes and maths 🤘 - please check out this PhD on the impact of metals on microbial communities with @thecopperdoctor.bsky.social @blindmath.bsky.social Denis Patterson and myself, you’d be based in Durham & be part of a vibrant interdisciplinary research group
Reposted by Conor (Conchúr) Meehan
With sessions on global antimicrobial healthcare, drug/resistance mechanisms, bacterial vaccines & immunotherapy, and antimicrobial combinations & interactions. @conmeehan.bsky.social & I have enjoyed putting the schedule together, hope to see lots of you in Birmingham next month! #MicroSky
October 21, 2025 at 8:02 AM
With sessions on global antimicrobial healthcare, drug/resistance mechanisms, bacterial vaccines & immunotherapy, and antimicrobial combinations & interactions. @conmeehan.bsky.social & I have enjoyed putting the schedule together, hope to see lots of you in Birmingham next month! #MicroSky
Hands down my favorite conference for meeting people in my field and hearing great science (and I don't just say thay cause I no co-chair). Come join us next month!
Join us in Birmingham for the annual BSAC #AntibioticResistance & Mechanisms workshop - excellent talks and it’s designed to make conversation & networking between attendees easy #MicroSky bsac.org.uk/antibiotic-r...
Antibiotic Resistance and Mechanisms (ARM) Workshop for Researchers 2025 - The British Society for Antimicrobial Chemotherapy
bsac.org.uk
October 21, 2025 at 8:17 AM
Hands down my favorite conference for meeting people in my field and hearing great science (and I don't just say thay cause I no co-chair). Come join us next month!
I'm trying to do some background reading on Hep C virus for a lecture. My first port of call tends to be 'Nature Disease Primers' to begin. So I find this one: www.nature.com/articles/nrd...
Why write a primer, which I assume you want people far and wide to read, and then have it behind a paywall???
Why write a primer, which I assume you want people far and wide to read, and then have it behind a paywall???
Hepatitis C virus infection - Nature Reviews Disease Primers
Hepatitis C virus infection can cause acute and chronic hepatitis C, which are both characterized by inflammation of the liver. In this Primer, Manns et al. describe the latest developments against th...
www.nature.com
October 16, 2025 at 10:26 AM
I'm trying to do some background reading on Hep C virus for a lecture. My first port of call tends to be 'Nature Disease Primers' to begin. So I find this one: www.nature.com/articles/nrd...
Why write a primer, which I assume you want people far and wide to read, and then have it behind a paywall???
Why write a primer, which I assume you want people far and wide to read, and then have it behind a paywall???