Cincinnati Children’s Research
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Immunity
@cp-immunity.bsky.social
· Sep 12
Tolerance to non-inherited maternal antigen is sustained by LysM+ CD11c+ maternal microchimeric cells
Pregnancy-induced microchimerism is linked with both inflammatory disorders and immune tolerance phenotypes. Peng et al. develop a platform for lineage-specific microchimeric cell depletion and show that tolerance to non-inherited maternal antigens is sustained by a small fraction of maternal microchimeric leukocyte cells identified by LysM and CD11c co-expression.
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Reposted by Cincinnati Children’s Research