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Mark Peifer (He, him) @peiferlabunc.bsky.social · 9d

Faculty positions in animal morphogenesis that may be filled at the Assistant or Associate Professor level in one of my favorite Departments" Cell and Systems Biology at the University of Toronto. 1/n
jobs.utoronto.ca/job/Toronto-...
jobs.utoronto.ca/job/Toronto-...

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Karolin Luger @nucleosomepolice.bsky.social · 11d

that time of the year... writing letters for 8 UG's applying to grad school, each of them to ~15 programs. And while I passionately support every one of them, thats A LOT of letters, a lot of web sites to keep track of, a lot of my time. Why dont Grad programs use interfolio? One and done???

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Mark Peifer (He, him) @peiferlabunc.bsky.social · 11d

After a "suspension" of just a few days, UNC Professor Dwayne Dixon is re-instated, revealing the weakness of the fabricated issues used for the suspension. Here is his response. Stand up to the fascists--when we work together we can triumph.

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Maik Bischoff @maikbischoff.bsky.social · 12d

My entry for today’s #FluorescenceFriday: a pupal #Drosophila testis with muscles expressing
🔵 lifeact &
🔴 RFP-nls

Honored & grateful to receive an honorable mention at @healthcare.nikon.com Nikon Small World 🌍🔬✨

🔗 www.nikonsmallworld.com/galleries/20...

#NikonSmallWorld #Microscopy #ScienceArt

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Mark Peifer (He, him) @peiferlabunc.bsky.social · 13d

Kate's work is remarkable--saw it at the Cell Contact and Adhesion GRC. Hiring faculty--she's a scientist to watch

Kate Cavanaugh @katecavanaugh.bsky.social · 14d

See this? This = implanting mouse embryo. Usually this happens inside its mother and is invisible to us, but we can actually watch implantation ex vivo with the hope of understanding why implantation goes awry in embryos of older women. A 🧵...

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Jeremy Berg @jeremymberg.bsky.social · 17d

A new email to Director Bhattacharya this morning.

1/n

Dear Director Bhattacharya:

I listened to more of your conversation with Glenn Beck. You made a number of statements that are false and misleading. You have considerable responsibilities in your current position and need to live up to them.

You dismiss critics of President Trump's comments at the press conference by saying:

"I think the key point here is something called "Trump Derangement Syndrome".

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@LaBonneLaB @labonnelab.bsky.social · 18d

"Head down focus on the science" folks: here is one super easy thing you can do today.

Mark Peifer (He, him) @peiferlabunc.bsky.social · 18d

Here's my comment--join me. This would effectively remove foreign PhD students and postdocs from our labs. please share

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Jeremy Berg @jeremymberg.bsky.social · 18d

An email to Director Bhattacharya to start the day

1/6

Dear Director Bhattacharya:

I attended the NIAID Council meeting online. I wanted to raise two points. First, I was disappointed that you sent a video of your presentation rather than showing up in person or, at least, attending live but virtually. You are missing out on important opportunities to interact with NIH staff and Advisory Council members. These individuals use their expertise and considerable time and energy to try to further the NIH mission. In addition, you are sending a signal about your priorities. This is especially true when you spend your time by appearing on The Glenn Show within a day. I realize that it was important to try to clean up the mess made primarily by President Trump at your press conference when he said repeatedly "Don't Take Tylenol!".

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Thea Jacobs @theajacobs.bsky.social · Sep 10

Super cool work from our institute!

Universität Münster @uni-muenster.de · Sep 8

Epithelial tissues cover the inner and outer surfaces of the body. A study by the working group of cell biologist Prof Carsten Grashoff now provides insight into the molecular details underlying the formation of the connections between epithelial cells. #Biology

How epithelial junctions mature: Study shows conformational transition in key protein

Epithelial tissues cover the inner and outer surfaces of the body. A study by the working group of cell biologist Prof. Carsten Grashoff now provides insight into the molecular details underlying the ...

www.uni-muenster.de

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Silvia Fre lab @frelab.bsky.social · Sep 9

Geometry first: how positional cues dictate fate in bilayered epithelia thenode.biologists.com/geometry-fir...

Geometry first: how positional cues dictate fate in bilayered epithelia - the Node

Behind the paper story focussed on research on early fate decisions in bilayered epithelia.

thenode.biologists.com

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bioRxivpreprint @biorxivpreprint.bsky.social · Sep 8

Top-Down Individual Ion Mass Spectrometry Reveals 85-110 kDa Catenin Phospho-Proteoforms Regulated by Actomyosin Contractility https://www.biorxiv.org/content/10.1101/2025.09.06.674621v1

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Mark Peifer (He, him) @peiferlabunc.bsky.social · Sep 6

I'm more than a little excited about this interstellar visitor 🧪
The images keep getting better and the insights deeper
PS this is just some of the science funded by the NSF that is threatened by devastating budget cuts--speak up and call Congress.
www.sci.news/astronomy/in...

Interstellar Comet 3I/ATLAS Displays Broad Coma and Growing Tail | Sci.News

Using the Gemini Multi-Object Spectrograph (GMOS) on the Gemini South telescope at NSF’s International Gemini Observatory in the Chilean Andes, astronomers have captured new multi-color images of the ...

www.sci.news

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paveltomancak.bsky.social @paveltomancak.bsky.social · Sep 4

We had #four interdisciplinary teams, integrating dev-bio, evolution, tissue mechanics, and biophysical modeling, all going full throttle to understand the #CF. Still, it took more than 7 years to publish two papers back-to-back (10/12)

www.nature.com/articles/s41...
www.nature.com/articles/s41...

Patterned invagination prevents mechanical instability during gastrulation - Nature

In Drosophila, the cephalic furrow counteracts mechanical stress as the developing head and the trunk tissues meet, providing evidence for how mechanical forces influence the evolution of morphog...

www.nature.com

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bioRxiv Cell Biology @biorxiv-cellbio.bsky.social · Aug 22

α-catenin phosphorylation is actomyosin-sensitive and required for epithelial barrier functions through Afadin https://www.biorxiv.org/content/10.1101/2025.08.21.671625v1

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Drug Monkey @drugmonkey.bsky.social · Aug 19

NIH progress on new R01s in FY 2025 drugmonkey.wordpress.com/2025/08/18/n...

NIH progress on new R01s in FY 2025

I know Doctor Editor Director Professor Berg has more sophisticated analyses going but this simple data set made sense to me once I realized how few new R01 NIAAA has issued so far (5). Since we ar…

drugmonkey.wordpress.com

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Jeremy Berg @jeremymberg.bsky.social · Aug 7

Indirect cost fun facts (from FY2024)

3 of the top 5 institutions in terms of negotiated indirect rates are pediatric hospitals.

The University of Kansas Medical Center had a higher negotiated indirect rate that Stanford.

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Maik Bischoff @maikbischoff.bsky.social · Jul 30

This thread below is criminally under-liked and under-shared!

Young #Drosophila researchers (PhDs, postdocs, and early-career Drosophilists): fill out the survey by Sept 1st to get matched with a mentor who can support you with your career.

Established Drosophilists, like/share Shefali's Thread ;)

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Richard Sever @richardsever.bsky.social · Jul 31

bioRxiv bat signal going up. We have a big backlog of submissions. If any affiliates have time to do some screening, we (and all the authors) would be immensely grateful! 🙏

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Jeremy Berg @jeremymberg.bsky.social · Jul 27

Post Sunday morning shows Bhattacharya email...

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Mark Peifer (He, him) @peiferlabunc.bsky.social · Jul 26

To better treat cancer, we need to understand its underlying biology. Despite decades of research, some fundamental questions remain unanswered. One is why certain key tumor suppressor or oncogenes lead to cancer predominantly in single tissue: e.g. Rb in the retina, or APC in the colon 1/n 🧪

Diagram illustrating the two-hit model of retinoblastoma

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David Gaboriau @dgaboriau.bsky.social · Jul 23

Getting closer to the “if proteins could talk…” moment of biochemistry

Nuno @nmachado.bsky.social · Jul 23

www.chemistryworld.com/features/ser...

Serial femtosecond crystallography reveals protein dynamics in real time

Proteins are constantly moving, but our structures of them are static. Clare Sansom talks to the researchers using free-electron lasers to make time-resolved structures

www.chemistryworld.com

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Mirre Simons @mirresimons.bsky.social · Jul 18

New preprint. ATF4 activation is thought to lead to longer lifespans. However, our study shows that suppression rather than activation extends lifespan in the fly. New Qs: how we can target ATF4 or its downstream targets to gain targeted longevity benefits.
www.biorxiv.org/content/10.1...

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Patrick Oakes @pwoakes.bsky.social · Jul 21

Congratulations to @stefanosala89.bsky.social , with help from @shreya-c.bsky.social al‬ on the optogenetic experiments, for the awesome story! Read the full preprint here: www.biorxiv.org/content/10.1... and thanks for listening!

LIM Domain Proteins link molecular and global tension by recognizing strained actin in adhesions

Mechanotransduction is fundamental to cell signaling and depends on force-sensitive adhesion proteins. How these proteins differentiate and integrate their responses to tension remains an open questio...

www.biorxiv.org

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Shailaja Seetharaman @sseethar.bsky.social · Jul 9

Excited to be starting my research group as a tenure track Presidential Young Professor at the Mechanobiology Institute @mbisg.bsky.social, and the Dept of Physiology at @nusingapore.bsky.social in the fall! More about our work on vascular mechanobiology in health & disease mechano-medicine-lab.com

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Frank Schnorrer @frankschnorrer.bsky.social · Jul 10

SARCOMERES divide! Mechanism how muscles grow while contracting - daughter sarcomeres appear everywhere. Seen live, registered on our cover. Pioneered by @clementrodier.bsky.social @friedrich-group.bsky.social Ian Estabrook @ibdm.bsky.social $ by @hfspo.bsky.social www.science.org/doi/10.1126/...

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