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Andrew Hardaway @andrewhardaway.bsky.social · 6h

RIP D'Angelo. Amazing talent and unreplicable sound.

D'Angelo, R&B's reluctant icon, has died at 51 www.npr.org/2025/10/14/n...

D'Angelo, R&B's reluctant icon, has died at 51

The expressive singer made just three albums, including his 1995 debut, Brown Sugar, but retreated from the public after each. He had been battling cancer, according to a statement from his family.

www.npr.org

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Andrew Hardaway @andrewhardaway.bsky.social · 11h

I aspire to the self-confidence of one who knowingly tucks his T-shirt into dad jeans with no belt.

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Reposted by Andrew Hardaway

Just Kevin @kevinleecaster.bsky.social · 1d

Batteries are now cheap enough to unleash solar’s full potential, getting as close as 97% of the way to delivering constant electricity supply 24 hours across 365 days cost-effectively.
ember-energy.org/latest-insig...

Solar electricity every hour of every day is here and it changes everything | Ember

Batteries are now cheap enough to unleash solar energy’s full potential, getting as close as 97% of the way to delivering constant electricity supply 24 hours across 365 days cost-effectively in the s...

ember-energy.org

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Andrew Hardaway @andrewhardaway.bsky.social · 1d

All #Titans fans right now

a man is standing in the rain and saying `` don 't give me hope '' .

ALT: a man is standing in the rain and saying `` don 't give me hope '' .

media.tenor.com

Reposted by Andrew Hardaway

George Pearkes @peark.es · 1d

great story, this chart RULES

Charts showing average battery pack cost in 2024 $/kWh and battery storage capacity additions globally in GW

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Andrew Hardaway @andrewhardaway.bsky.social · 1d

Congrats Jibran!

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Reposted by Andrew Hardaway

Jibran Khokhar @drjkhokhar.bsky.social · 1d

Excited to share recent collaborative work led by Hayley Thorpe published in Molecular Psychiatry: Genome-wide association studies of lifetime and frequency of cannabis use in 131,895 individuals www.nature.com/articles/s41...

Genome-wide association studies of lifetime and frequency of cannabis use in 131,895 individuals - Molecular Psychiatry

Molecular Psychiatry - Genome-wide association studies of lifetime and frequency of cannabis use in 131,895 individuals

www.nature.com

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Andrew Hardaway @andrewhardaway.bsky.social · 2d

Rules matter!

Wait, sorry I've just been informed the NFL has a rules committee whose inaction or action has shaped the state of play for two decades. See: Illegal contact, kickoffs, challengeable pass interference to back off again.

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Andrew Hardaway @andrewhardaway.bsky.social · 2d

a man in a plaid jacket says cool cool cool cool .

ALT: a man in a plaid jacket says cool cool cool cool .

media.tenor.com

Reposted by Andrew Hardaway

Laprofmme @laprofmme.bsky.social · 2d

Courtesy of colleagues at Penn

A variation on Benjamin Franklin’s 1754 engraving in the Pennsylvania Gazette, published in Philadelphia, in an effort to foster cooperation among the various colonies against the tyrant king of Britain, with the American colonies replaced by the nine universities selected for special collaboration opportunities

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Andrew Hardaway @andrewhardaway.bsky.social · 2d

This baby boy had a bath and is feeling extra cuddly.

Bruce, a great pyrenees male dog, lying on the couch

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Andrew Hardaway @andrewhardaway.bsky.social · 2d

a man is making a stop sign with his hands and the words `` hold me now '' written below him .

ALT: a man is making a stop sign with his hands and the words `` hold me now '' written below him .

media.tenor.com

Reposted by Andrew Hardaway

Sarah J. Jackson @sjjphd.bsky.social · 3d

I’m not trying to give @pbs.org ideas for raising money—but I am. I would buy women’s fit T-shirts of all my favorite childhood shows. Reading rainbow, 321 contact, square one, zoobiliee zoo. I feel like two generations will run to donate even more money for shirts with Levar Burton on them…

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Reposted by Andrew Hardaway

Chise @sailorrooscout.bsky.social · 6d

GOOD NEWS! Researchers have discovered a powerful antibody, known as 04_A06, that is able to neutralize 98.5% of MORE THAN 300 different HIV strains AND permanently reduce HIV viral load to undetectable levels, making it one of the broadest-acting antibodies against HIV identified to date.

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Reposted by Andrew Hardaway

Cells & Development @cellsdev.bsky.social · 3d

In honor of the passing of Sir John Gurdon, we will revisit the concept of chimerism across scales in this review from the lab of @drmichaellevin.bsky.social. Grafting and nucleus transplanting have been the cornerstone of modern #devbio. We have come so far!
www.sciencedirect.com/science/arti...

Schematic of the study of multiscale chimerism.

Chimeras at different scales: subcellular, molecular, cellular, tissue, organ, and population.

What determines the anatomical setpoint of regenerative homeostasis?

Planarian flatworms regenerate after amputation using a resident population of stem cells. This process reliably stops when the correct species-specific head shape is restored. The following thought experiment illustrates the profound knowledge gap in our understanding of the rules of morphogenesis despite ample information about genes required for neoblast differentiation.

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Andrew Hardaway @andrewhardaway.bsky.social · 4d

These are terrific ideas.

Aaron Rupar @atrupar.com · 4d

Thune: "If the Democrats had won the majority, they probably would've tried to nuke the filibuster. And then you'd have four new senators from Puerto Rico and DC, you'd have a packed Supreme Court, you'd have abortion on demand ... "

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Andrew Hardaway @andrewhardaway.bsky.social · 5d

Awesome news! Congrats!

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Reposted by Andrew Hardaway

Ann Kennedy @antihebbiann.bsky.social · 5d

Finally out: our recent work with Nick Betley is a view into how the brain reshapes its behavior in the face of competing survival needs- and also a potential angle on treatment targets for enduring pain.

A brief rundown...

www.nature.com/articles/s41...

A parabrachial hub for need-state control of enduring pain - Nature

Activity in a set of parabranchial neurons in the mouse brain is increased during chronic pain, predicts coping behaviour, and can be modulated by circuits activated by survival threats.

www.nature.com

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Reposted by Andrew Hardaway

Patrick Piantadosi @ppiantad.bsky.social · 5d

for anyone interested in the amygdala and risky decision-making, check out our new preprint: biorxiv.org/content/10.1...

amygdala neurons track reward-seeking actions, and punishment risk dramatically alters this function. lots of other (BLA-accumbens!) data included.

Risk reshapes amygdala representation of choice

Modifying behavior in response to changing environmental conditions is a crucial adaptive function. This capacity is exemplified when animals curtail pursuit of a valued outcome that risks being punis...

biorxiv.org

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Reposted by Andrew Hardaway

Loren DeJonge Schulman @lorenraeds.bsky.social · 7d

Former OMB associate director on personnel here: This is blatantly false and inexplicably undermines Congress's authority. Congress made extremely clear in 2019 that furloughed feds are to be paid, full stop, period. There is no question, except why the Speaker would make such a statement.

Aaron Rupar @atrupar.com · 7d

Johnson: "It's true that in previous shutdowns, many or most furloughed employees have been paid for the time they were furloughed, but there is new legal analysis - I don't know the details, I just saw a headline - but there are some legal analysts saying that might not be appropriate or necessary"

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Andrew Hardaway @andrewhardaway.bsky.social · 6d

People who know me know I rarely shill for much, but my experience at UAB as a family member of a patient was amazing. Huge thanks to Neurosurgery and Drs. Kristen Riley, Brad Woodworth, and Harrison Walker (Neurology).

Andrew Hardaway @andrewhardaway.bsky.social · 6d

Context here. In August, my mom developed a CSF leak and subsequent pneumocephalus. Her initial ENT and neurosurgeon were unable to identify the leak and were suggesting a full and bilateral craniotomy to go in and fix it. I moved her to UAB and she got the care she needed. She is recovering well.

Andrew Hardaway @andrewhardaway.bsky.social · 6d

Flip side, you can also have n = 1 patient like my mom being treated by a highly trained neurosurgeon who was suggesting a highly risky and invasive surgery that is no longer the standard of care and it was only by me (not an MD) challenging the surgeon that she got the procedure she needed.

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Andrew Hardaway @andrewhardaway.bsky.social · 6d

Completely agree. And I hate that we are in an age where armchair podcasters seem to have more influence than those with actual expertise. I think my mom's was a rare case, but it's one where me being a salty questioner of authority paid off and the authority had it wrong.

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Andrew Hardaway @andrewhardaway.bsky.social · 6d

Context here. In August, my mom developed a CSF leak and subsequent pneumocephalus. Her initial ENT and neurosurgeon were unable to identify the leak and were suggesting a full and bilateral craniotomy to go in and fix it. I moved her to UAB and she got the care she needed. She is recovering well.

Andrew Hardaway @andrewhardaway.bsky.social · 6d

Flip side, you can also have n = 1 patient like my mom being treated by a highly trained neurosurgeon who was suggesting a highly risky and invasive surgery that is no longer the standard of care and it was only by me (not an MD) challenging the surgeon that she got the procedure she needed.

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Andrew Hardaway @andrewhardaway.bsky.social · 6d

I wanna be clear that I am not trying to dump on all MDs and that I value data and expertise.

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Andrew Hardaway @andrewhardaway.bsky.social · 6d

Clearly there is a role for expertise. I am not suggesting otherwise and I also don't like it when individuals overextrapolate from a limited sample of experience. What was helpful in my case was being connected with multiple physicians and being a neuroscientist - privilege.

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