Sonja Welsch
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sonjawelsch.bsky.social
Sonja Welsch
@sonjawelsch.bsky.social
2.4K followers 920 following 210 posts
Taking care of Electron Microscopy @mpibp.bsky.social. Yay for #cryoEM and #cryoET ❄️🔬but frozen is not always better. Also, #viruses 🦠 rule.
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Reposted by Sonja Welsch
Thrilled, and admittedly relieved, to see this major investment in Dutch #cryoEM become reality! 🇳🇱🔬

Honoured to be a co-applicant on this national initiative and very excited for the opportunity to advance our work in cellular structural virology! 🦠

www.uu.nl/en/news/33-m...
33 million euro investment for national electron microscope facility EMPower
A major new national facility for electron microscopy, called EMPower, has been awarded to a consortium of Dutch universities and medical centers. EMPower aims to pave the way for major discoveries im...
www.uu.nl
Looking for an exciting #cryoEM postdoc position? 🤩 This one is highly recommended! 👇
We are looking for motivated #postdocs to join the lab! Biochemistry/microbiology/cryo-EM experience? Excited by #cryo-EM/ET, #chromatin? ❄️🧬🧫
Interdisciplinary projects, top EMBL facilities!
Email CV + short cover letter → [email protected]
Info about the group: www.embl.org/groups/dodon...
Dodonova Group – Organisational principles and 3D architecture of archaeal chromatin
www.embl.org
Reposted by Sonja Welsch
Lab’s first paper is out!! We show the first structures of #Asgard #chromatin by #cryo-EM 🧬❄️
Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...
Reposted by Sonja Welsch
Have you registered to the next EMBO Practical Course on In-situ structural biology by Cryo-FIB and Cryo-ET? 🧊 Join us in Frankfurt for hands-on training on cryo-techniques and networking with experts!

🔗 Apply by Dec 8, 2025: meetings.embo.org/event/26-in-...
📍 Frankfurt | 📆 April 12–20, 2026
Reposted by Sonja Welsch
Mysteries of trafficking of the vRNP segmented genome and assembly of influenza A virus revealed by in situ cryo-ET!
🔗 rdcu.be/eMmct
We are very excited that our paper is finally out!
🎉 Big congratulations to Moritz Wachsmuth-Melm and to everyone involved.
@mpibp.bsky.social’s handsome STEM scan of the day 🤩
Guess the crystal? Hint: S136
Reposted by Sonja Welsch
I just made an account and voted for this biology laboratory made of LEGO to "promote biological research and inspire more people into the world of biology". They need 10K votes. Reposting and/or voting below would be helpful. 🤗
beta.ideas.lego.com/product-idea...
Biological Laboratory | LEGO® Ideas
This is a two-floor realistic Biological Laboratory building. In this design, I try to tell stories about biologists, introduce biology concepts to general publ…
beta.ideas.lego.com
octagon pressure too high
If I could ask all #cryoEM samples for one thing, it’d be to *please* behave like 1um TetraSpecks.
Only a few days left to apply for the great PhD Programme of @vbcscitraining.bsky.social 👇🏻
Our PhD program offers many training activities and courses for your future career. Check out the range of fully-funded PhD positions in our Autumn call before 10 October 2025: www.vbcphd.at
Reposted by Sonja Welsch
Correlative MS Imaging for cellular identification and analysis of in situ cryo-ET www.biorxiv.org/content/10.1101/2025.09.16.676641v1 #cryoem
I see at least 4 that I’d swear aren’t apo
Reposted by Sonja Welsch
Since it was published at peak holiday season, I'm taking the liberty to re-introduce our recent review article. We hope it will be a useful overview of RNA virus replication strategies, and how in situ cryo-EM have helped us understand them:
www.sciencedirect.com/science/arti...
Illuminating druggable dark matter in RNA virus replication using in situ cryo-EM
Viral proteins typically exist in the context of complex virions or in the even more complex host cells in which they replicate. Hence, meaningful ins…
www.sciencedirect.com
Reposted by Sonja Welsch
Ever wondered how to position organelles in bacteria? Wonder no more!
Happy to have contributed to this fantastic story from @cellforganized.bsky.social' lab.

The avenues this opens in the synthetic biology space are enormous!

Movie: Carboxysomes positioned in E. coli!

Preprint: shorturl.at/D6xVg
Reposted by Sonja Welsch
We welcome our new faculty member Ramachandra Bhaskara! His group uses simulations and modeling to study complex biological systems at the interface of biology, physics, and data science.
#imprs #imprs_cbp @goetheuni.bsky.social
Reposted by Sonja Welsch
We followed with a day packed with CryoEM! We heard about the cryoEM from Werner Kühlbrandt, STEM-EELs from Bonnie Murphy and CryoET from Martin Beck.
Reposted by Sonja Welsch
A productive morning with Profs. Dötsch, García-Sáez and Helfrich! We learnt about transcription factors, cellular death and biosynthetic pathways. All before lunch time! #sciencemorning #gradschool @mpibp.bsky.social @goetheuni.bsky.social
At what number of hidden layers do shallow learning networks cross over to being deep learning? One? More? Depends?🤔
I’d also throw “general problem solving skills” in the mix - and requirements for being good at problem solving might indeed change over time (as the nature of open questions tends to shift over time)?
Reposted by Sonja Welsch
First webinar on the kit this Thu Sep 18th. You can still register in one of the links below.
Our aim was to create a kit to produce in-house 1.2 holey carbon cryoEM grids, in three simple steps, at less than half of the prize, and without due times. I think we are there. Academic teams that want to know more, receive training or order a kit, please contact [email protected].