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Reposted by Roshni Patel

Graham Coop @gcbias.bsky.social · 7h

We're excited to be recruiting an NIH funded postdoc to work in the Coop lab at UC Davis. We're specifically interested in candidates who are want to work at the intersection of human genetics, GWAS, and population genetics modeling. Please RT

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Roshni Patel @roshnipatel.bsky.social · 10h

I'm recruiting a postdoc for my group (based in beautiful Eugene, OR). Please get in touch if you're interested, esp if you'd like to chat at #ASHG25!

Roshni Patel @roshnipatel.bsky.social · Aug 6

We'll primarily work at the intersection of statistical and population genetics, and we also have active projects related to the ethical and social implications of human genetics (ELSI). Please get in touch if that's a combination that sounds interesting to you!

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Hakhamanesh Mostafavi @hakha.bsky.social · 1d

I’ll be attending #ASHG25! I’m currently hiring for (i) a Senior Research Scientist or (ii) a Postdoc position in my lab. If you’re interested, please reach out to arrange a time to meet and discuss.

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Polly Fordyce @pollyfordyce.bsky.social · 1d

Applications are due tomorrow! Apply to come and join us @stanford-chemh.bsky.social -- it's a truly wonderful place to launch a career in interdisciplinary molecular research.

Sarafan ChEM-H @stanford-chemh.bsky.social · Aug 26

Open faculty position!
We're seeking applicants for a tenure-track faculty position at the junior level (Assistant or untenured Associate Professor) with research programs that exist at the interface between molecular science and computation. Apply here: stanford.io/45MF3Qa

Open Faculty Position: Assistant or Associate (Untenured) Professor

Application deadline: 11:55 PM on Wednesday, October 15, 2025

Sarafan ChEM-H is seeking candidates with research programs that exist at the interface between molecular science and computation.

Click the link above to learn more & apply!

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Jon Phillips @jowiph.bsky.social · 1d

Only tangentially related, but a certain Russian-American geneticist once received a passport randomly assigning him the middle initial J (he had no middle name). On a trip to Brazil, an official wouldn't let him in with just J on the paperwork, so he became Theodosius Juan Dobzhansky

There was a hitch, at the very end. Well, a very minor hitch was that when my passport came from Washington, -- of course,
getting a foreign passport in wartine was not so easy -- I have sudenly acquire? a second initial. Just how it happened, I have not the faintest tea, but the passport came for somebody caller The posius J. Dobzhansky, So ever since, I was "J."

Q: ft's really H, len't 1t? Or none at all?
Dobzhansky: No -- tbere 1a no socond initial, of course, at all.
But naturally It would have been nothing short of foolish to send a passport obtained with such difficulty, after presumably investigations and so on, in order to remove a J. All my passports since have had a J. I am presumably legally a J. now.
*: Did you make up a name to go with 1t?
Dobzhansky: Yes. At one time, also in Brazil, when a not very Intelligent Brazilian official demanded that I have a second name, as 1t should be, after several attempta to explain to him tbat I baa no socond name, I finally decided, why not Juan?
*: Then you have a Brazilian second name.
Dobzhansky: So I have a Brazilian second name.

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Reposted by Roshni Patel

PLOS Biology @plosbiology.org · 1d

Genetic architectures of #ComplexTraits vary widely. @yuvalsim.bsky.social @jkpritch.bsky.social @gs2747.bsky.social &co show these diffs arise from mutational target size & heritability per site; when controlled for, all tested traits have similar architectures @plosbiology.org 🧪 plos.io/47mZXqT

Heritability and target size underlie differences between trait architectures:

examples for three traits. Top: Height (blue) and platelet crit (red) have the same heritability per site h2/L, but height has a much higher mutational target size L. This results in many more hits for height (1533) than for platelet crit (648) (2 left panels). However, the marginal distributions of effect sizes, MAFs, and z-scores of hits are nearly identical for the two traits (3 right panels). Middle: Height (blue) and FEV1 (gold) differ in h2/L, but have similar L. Consequently, the joint distribution of z-scores and MAFs of their hits are markedly different (2 left panels), as are the marginal distributions of hit effect sizes, MAFs and z-scores (right). Bottom: After scaling by their respective , and imposing the more stringent scaled significance threshold (corresponding to FEV1) for both traits, the joint distribution of z-scores and MAFs of their hits (2 left panels) and the corresponding marginal distributions (3 right panels) are highly similar.

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Arbel Harpak @arbelharpak.bsky.social · 1d

If you are at #ASHG2025 and would like to chat in person, please reach out! My lab is looking for curious scientists to join us, especially (but not limited to) postdoctoral researchers.

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Ian Weissman, DO @drianweissman.bsky.social · 3d

“CDC will have lost its ability to detect outbreaks and respond to them. It will no longer be able to track diseases, in America and around the globe. That includes infectious threats like flu, foodborne illnesses, and Ebola, as well as chronic diseases and injuries.”
time.com/7325192/cdc-...

CDC ‘Not Functional’ After Trump Administration Orders Mass Firings

The layoffs targeted leaders in departments related to respiratory diseases, chronic diseases and global health.

time.com

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Iris van Rooij 💭 @irisvanrooij.bsky.social · 3d

“If you share your knowledge outside the scientific community, then you’re already exerting societal influence, according to Judi Mesman. This isn’t problematic for the prestige of science: ‘Pretending to be neutral doesn’t make sense to me.’”

www.nwo.nl/en/there-is-...

‘There is no clear boundary between science and activism’ | NWO

If you share your knowledge outside the scientific community, then you’re already exerting societal influence, according to Judi Mesman. This isn’t problematic for the prestige of science: ‘Pretending to be neutral doesn’t make sense to me.’

www.nwo.nl

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Ryan Hernandez @rdhernand.bsky.social · 6d

There are unprecedented challenges for science, calling for bold action and collective effort. Training the next generation of scientific leaders has never been more important. Join us as we grow National PROPEL to answer this call. Learn more: propelscholars.org @propelscholars.bsky.social 🧪🧬🖥️🧵

Building a community of PROPEL-affiliated programs at UCSF, U. Utah, UCSC, MUSC, U. Iowa, UW/Fred Hutch, OHSU, and Stanford!

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National PROPEL @propelscholars.bsky.social · 5d

Looking for a start in science? National PROPEL will host faculty looking to hire full-time research technicians from 5 institutions on Jan 30th. Meet faculty with similar research interests in a series of 10 min interviews. More info at propelscholars.org/matchmaking-event

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Anne Carpenter @drannecarpenter.bsky.social · 5d

15 years in the making, we confirmed that mitochondria - the powerhouse of the cell - have an unusual localization in patients who experience psychosis (including schizophrenia and bipolar disorders). You’ll never guess what kind of patient cells we used to make this discovery… 🧵

mitochondria from bipolar patients are closer to the nucleus in these images; control patients' are spread out further

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Liz Aguilar @liz-aguilar.bsky.social · 5d

I can’t think of a better reason to finally join Bluesky - my first first-authored paper is out! It being published in @science.org is surreal. This was a community effort in every sense, led by an incredible team with @rosvall-lab.bsky.social @mathcancer.bsky.social @juncowren.bsky.social

Science Magazine @science.org · 6d

As the Moon eclipsed the Sun on 8 April 2024, birds took note.

Leveraging nature’s own experiment, scientists and the public joined forces to show how different species responded to sudden midafternoon darkness followed by a new “dawn.” Learn more this week in Science: https://scim.ag/48WbhLL

As the Moon eclipsed the Sun on 8 April 2024, birds like these rock pigeons (Columba livia) took note.

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Eric Turkheimer @ent3c.bsky.social · 6d

Blog post: Ancestry and Education
Indirect, direct, confounded and quasi-causal.

I write about a preprint by Wang et al, in which they look for associations with genetic ancestry in an admixed Mexican population. They found genetic effects for height and Type-II diabetes, but not for education.

Ancestry and Education

Indirect, direct, confounded and quasi-causal

ericturkheimer.substack.com

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Jeffrey Ross-Ibarra @jrossibarra.bsky.social · 6d

PEQG website live! genetics-gsa.org/peqg-2026/

Homepage - 2026 Population, Evolutionary, and Quantitative Genetics Conference

Visit our website to learn more.

genetics-gsa.org

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Beyond X&Y @beyondxandy.bsky.social · 9d

"Who decides what is normal development? Who decides what is natural biodiversity or pathological deviation? Who defines the distinction between defect and difference?"

Eugenic attacks on people who are disabled, neurodivergent, queer, trans... They are all linked by fear of diversity

the Node @the-node.bsky.social · 9d

Developmental Biology and Disability.

“Developmental biology is fundamentally beautiful. We are no less beautiful for our variation. Instead, perhaps we are more so. Perhaps we are remarkable. Perhaps we are full of wonder.”

Insightful post by Bethan ⬇️👀
thenode.biologists.com/developmenta...

Developmental Biology and Disability - the Node

Hopeful monsters. Morphospace. Mutation. Natural variation. Mutagenesis screens. Polymorphism. Deformity. Phenotype. Disease. Adaptation. Anomaly.

thenode.biologists.com

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Andrew Iwaniuk @evoneuro.bsky.social · 6d

As I tell my students, if you arrived at a simple answer in biology you have done one of two things: arrived at the wrong answer or asked the wrong question

Claus Wilke @clauswilke.com · 8d

Biology is much more complicated than most non-biologists can imagine. And AI is not going to change this anytime soon.
blog.genesmindsmachines.com/p/we-still-c...

We still can’t predict much of anything in biology

Biology is hard. Yes, even for AI.

blog.genesmindsmachines.com

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Joshua G. Schraiber @jgschraiber.bsky.social · 9d

Just an absolutely horrific self own, depleting the US of amazing students from all over the world who contributed to what used to make America great: its diversity, its openness, and its leadership in education.

The New York Times @nytimes.com · 9d

The number of international students arriving in the U.S. in August fell by 19% this year compared with last year — the largest decline on record outside of the pandemic.

Nearly 20 Percent Fewer International Students Traveled to the U.S. in August

The data shows the steepest decline in August international student arrivals since the pandemic.

nyti.ms

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Mike Wiser @drmikewiser.bsky.social · 13d

That's not most people, obviously, but it's also not that rare.

To put that in perspective: people who are neither XX nor XY are more common than people with Multiple Sclerosis. Roughly as common as people with Down syndrome, or people with Parkinson's disease.

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D. J. Hicks @danhicks.bsky.social · 14d

Finally officially published! "Race science in mainstream psychology, 1960–2010" with @rhacodactylus.bsky.social (who needs a job btw) direct.mit.edu/qss/article/... 🧵

#histsci #sts #philsci #metascience

Race science in mainstream psychology, 1960–2010

Abstract. Anthropologists and human geneticists have long rejected efforts to purportedly scientifically justify racial inequality and colonialism. But race science has persisted, at least on the marg...

direct.mit.edu

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Dr. Jey McCreight 🧬🏳️‍⚧️ @jeymccreight.bsky.social · 22d

Proud to announce the project I've been working on 🏳️‍⚧️🧬

Had hoped to have more ready, but the events of the last week stressed the importance of speaking up against fascism NOW

I'd appreciate your support in spreading the word, esp if you work in life sciences research, healthcare, or biotech

Beyond X&Y @beyondxandy.bsky.social · 22d

It's the scientific community's duty to fight misinformation, bioessentialism, and eugenics

That's why we're launching Beyond X&Y, an educational campaign combating the rise of unscientific political propaganda used to attack trans and intersex people

Subscribe to our newsletter at beyondxandy.org

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Jazlyn Mooney @jazlynmooney.bsky.social · 23d

Super excited to see our reference bias work out in Cell! Reviewers gave us some excellent ideas, and Maria added on some new analyses that broke down how SNPs from heterospecific references mapped or did not map in a conspecific reference.

Maria Akopyan, PhD @akopyan.bsky.social · 23d

Now published in Cell! We found that ~15% of SNPs from divergent refs did not liftover as SNPs in the gray fox ref—half mapped to monomorphic sites, half failed to map. Co-authored with Matthew Genchev, @elliecat.bsky.social, and @jazlynmooney.bsky.social

www.sciencedirect.com/science/arti...

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Gen Wojcik @genandgenes.bsky.social · 23d

There is a strange pain that comes from the scientific field you work in being weaponized to hurt people.

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Jeffrey Ross-Ibarra @jrossibarra.bsky.social · Sep 3

Save the date! #PEQG26 June 9-12 2026 in Asilomar, CA. Happens only every 2yrs, but is my favorite conference. Full website coming soon, and registration and abstract submission opens November 14, but I'm allowed to tease that keynotes will be @jnovembre.bsky.social @jennytung.bsky.social and me!

Homepage - Population, Evolutionary, and Quantitative Genetics Conference

Visit our website to learn more.

genetics-gsa.org

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Chris Marcum 📖 @csmarcum.sciences.social.ap.brid.gy · Sep 12

The ethical, legal, and social implications program successfully protected society from many risks of harm in genomics. Alondra Nelson argues we need such a framework - post haste - for AI in this thoughtful letter to Science Magazine :

https://www.science.org/doi/10.1126/science.aeb0393

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