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Dr Radu Zabet

@raduzabet.bsky.social

2.8K followers 2.9K following 160 posts

Group Leader - Reader (Assoc. Professor) in AI and Cancer Epigenetics at Blizard Institute, Queen Mary University of London. #GeneRegulation, #Chromatin, #Epigenetics, #AI, #bioinformatics https://www.qmul.ac.uk/blizard/all-staff/profiles/radu-zabet.html

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Reposted by Dr Radu Zabet

MRC Cognition and Brain Sciences Unit, University of Cambridge @mrccbu.bsky.social · 19h

New paper - Sex differences in healthy brain aging are unlikely to explain higher Alzheimer’s Disease prevalence in women: https://doi.org/10.1073/pnas.2510486122

Dr Radu Zabet @raduzabet.bsky.social · 19h

Thanks Sandra for the feedback. We were planning to look into that as well, but we haven't started yet.

Dr Radu Zabet @raduzabet.bsky.social · 20h

This work was led by Young Jun Kim, a very talented student in the lab. If you have ONT data and want to investigate DNA methylation, DMRcaller would be able to provide you more information than what was previously possible.

Dr Radu Zabet @raduzabet.bsky.social · 20h

This allows using the previous functionality of the package, but also new functionality such as (co-methylation of individual cytosines or whole regions, detection of variable methylated regions and detection partially methylated domains among others).

Dr Radu Zabet @raduzabet.bsky.social · 20h

We extended the functionality of DMRcaller ( bioconductor.org/packages/DMR...) to incorporate ONT data directly from Dorado aligned bam files and maintain the information of the read the modification was detected on.

Dr Radu Zabet @raduzabet.bsky.social · 20h

Oxford Nanopore Technologies (ONT) sequencing has emerged as a novel technique to sequence directly long strands of DNA without chemically treating the DNA. ONT can also extract epigenetic status of the nucleotides, including both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC).

Dr Radu Zabet @raduzabet.bsky.social · 20h

We previously developed DMRcaller, a Bioconductor package for the analysis of DNA methylation data from WGBS (academic.oup.com/nar/article/...). This is a highly versatile tool that allows great flexibility in detecting Differential DNA methylation in CpG and non-CpG context.

Dr Radu Zabet @raduzabet.bsky.social · 20h

DNA methylation is one of the most studied epigenetic modification associated with regulation of gene expression. Bisulfite-converted genomic DNA sequencing has been the current gold standard in the field for building genome-wide DNAm maps at base pair resolution.

Reposted by Dr Radu Zabet

Lucas Farnung @lucas.farnunglab.com · 1d

We have added new functionality to include a plot of protein disorder using IUPred scores generated by iupred2a.elte.hu. Generate IUPred scores for your POI and upload the JSON file to generate this plot.

Reposted by Dr Radu Zabet

Wolfgang Busch @rootstrapping.bsky.social · 1d

🌿 Amazing opportunity for scientists from any field to move into plant biology! I might host a fellow in the area of root-microbe or root-environment interactions (DM me). 👉 simonsfoundation.org/grant/simons-postdoctoral-fellowships-in-plant-biology

#PlantScience #ClimateChange #HarnessingPlants

Simons Postdoctoral Fellowships in Plant Biology

Simons Postdoctoral Fellowships in Plant Biology on Simons Foundation

simonsfoundation.org

Reposted by Dr Radu Zabet

FragileNucleosome @fnucleosome.bsky.social · 22h

👀Next Wednesday, Oct 22nd, at #FragileNucleosome seminar, we are excited to host @alicelaigle.bsky.social and @seungsookim.bsky.social to tell us about amazing work they are doing!
🗓️Register here for upcoming session and the entire series:
us06web.zoom.us/webinar/regi...

Reposted by Dr Radu Zabet

Drosophila Spain @drosospain.bsky.social · 1d

We are pleased to announce that the 2nd DrosoSpain meeting #DrosoSpain2026 will take place in San Joan de Alicante from the 9th to the 11th of April 2026 #savethedate

Reposted by Dr Radu Zabet

Mark Peifer (He, him) @peiferlabunc.bsky.social · 2d

I'm very excited to announce that UNC Biology has 6 faculty positions open this year! The first is for an Asst Professor who studies organismal resilience using an integrative approach 1/n
unc.peopleadmin.com/postings/307...

Poster with QR code linking to the position

Reposted by Dr Radu Zabet

Eva Stukenbrock @estukenbrock.bsky.social · 2d

Professorship in plant genetics.
The Botanical Institute at Kiel University is advertising a W2 professorship. Great opportunity to do plant research in the north of Germany. See:
www.berufungen.uni-kiel.de/de/dateien/o...

www.berufungen.uni-kiel.de

Reposted by Dr Radu Zabet

zaira seferbekova 👩🏻‍💻 @zaira-sef.bsky.social · 8d

🚨 new glioblastoma preprint alert!

we present the first spatially resolved single cell atlas comparing radionecrotic changes (RN) and recurrent IDH-wildtype glioblastoma (GB) –– shedding light on a long-standing diagnostic challenge.

🧵 1/

Reposted by Dr Radu Zabet

Waggoner Lab @labwaggoner.bsky.social · 3d

@biorxivpreprint.bsky.social Scalable transcription factor mapping uncovers the regulatory dynamics of natural and synthetic transcription factors in human T cell states
www.biorxiv.org/content/10.1...

Reposted by Dr Radu Zabet

Daniel Durocher @durocher1.bsky.social · 3d

9 days to go:
* 2 x open positions!
* Exceptional environment, competitive start-up package
* University of Toronto appointments
* Toronto has great (and peaceful) quality of life!

Daniel Durocher @durocher1.bsky.social · Aug 28

JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada at @sinaihealth.bsky.social. We provide a generous startup, fully funded salary and academic appointment at U of Toronto.

www.nature.com/naturecareer...

Please repost!

Image of Toronto

Reposted by Dr Radu Zabet

Trish Greenhalgh @trishgreenhalgh.bsky.social · 2d

Well done Shafaq Aftab. When a reviewer stole her work and published it under his own name, she fought for a YEAR to get the journal to retract the paper. Just wondering why it took Wiley a YEAR to do this. 🧪 #academicsky

retractionwatch.com/2025/10/03/w...

Wiley retracts study stolen by reviewer, following Retraction Watch coverage

A Wiley journal has retracted a paper more than a year after a researcher reported the work was hers and had been stolen by a reviewer for another journal. As we reported in July, Shafaq Aftab, now…

retractionwatch.com

Reposted by Dr Radu Zabet

Anne Carpenter @drannecarpenter.bsky.social · 4d

15 years in the making, we confirmed that mitochondria - the powerhouse of the cell - have an unusual localization in patients who experience psychosis (including schizophrenia and bipolar disorders). You’ll never guess what kind of patient cells we used to make this discovery… 🧵

mitochondria from bipolar patients are closer to the nucleus in these images; control patients' are spread out further

Reposted by Dr Radu Zabet

Alexis Barr @alexisbarr.bsky.social · 5d

Many of you know, we lost Béla Novák this year. John Tyson, Francis Barr & I tried to capture his wonderful character & great mind so that those that didn't know him can see what a fantastic person he was.

Thanks to @jcellsci.bsky.social for publishing.

journals.biologists.com/jcs/article/...

Béla Novák (1956–2025) – a legacy of scientific discovery and personal charm

In February 2025, we were shocked and deeply saddened to hear about the death of Béla Novák, Professor in Integrative Systems Biology at the University of Oxford, UK, and a beloved grandfather, father...

journals.biologists.com

Reposted by Dr Radu Zabet

James Briscoe @jamesbriscoe.bsky.social · 4d

The @crick.ac.uk is recruiting Early Career Group Leaders

- Lab set-up, research costs, salaries for up to 5 researchers
- Support for up to 12 years
- Access to our core facilities
- Competitive salary
- Fantastic colleagues
- All areas of biology

Deadline 27 Nov

www.crick.ac.uk/careers-stud...

Early career group leaders

We appoint researchers from across biology and biomedicine to set up their first groups at the Crick.

www.crick.ac.uk

Reposted by Dr Radu Zabet

Sainsbury Laboratory Cambridge University (SLCU) @slcuplants.bsky.social · 5d

Salicylic acid biosensor, SalicS1, tracks the plant immune hormone salicylic acid in real time - revealing propagation of hormone surge during plant pathogen advance

Latest biosensor from @xanderjones.bsky.social team
In Science doi.org/10.1126/scie...
Summary www.slcu.cam.ac.uk/news/new-bio...

Reposted by Dr Radu Zabet

Giles Wilkes @gilesyb.bsky.social · 4d

"if anything employment outcomes are worsening more rapidly for those with fewer skills looking for blue-collar jobs than the highly skilled seeking knowledge work"

on.ft.com/43eYeRZ

@jburnmurdoch.ft.com as ever doing the essential work.

It's not just AI. And education still matters

What the graduate unemployment story gets wrong

People with a degree are faring better, not worse than their non-graduate counterparts

Reposted by Dr Radu Zabet

Naomi Moris @nmoris.bsky.social · 5d

The Crick is looking for new junior group leaders! Any postdocs or early career researchers wanting to be our colleagues should apply 👍

The Francis Crick Institute @crick.ac.uk · 5d

We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions.

Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.

Apply now ➡️ www.crick.ac.uk/careers-stud...

Reposted by Dr Radu Zabet

Guillaume Bourque @guilbourque.bsky.social · 5d

🚨 New paper alert on telomeres! 🚨
Something different from the group! Thanks to Yuxin, a talented student in the lab, we used long-reads in 75 human trios to study telomeres and their inheritance.