Author | Lightnews

Nat Marshall

@natsleep.bsky.social

220 followers 250 following 37 posts

Sleep epidemiologist and clinical triallist at the Woolcock Institute and Professor at Macquarie University, Sydney, Australia. Editor at SLEEP and J Sleep Res. #SleepPeeps Clinical Researcher Development. Hurkle-durkler. Statistical grief counselor

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Nat Marshall @natsleep.bsky.social · Sep 3

I used to have children who did that

Nat Marshall @natsleep.bsky.social · Jul 29

Definately my weirdest scientific idea yet: Can humans sleep one half of their brains at a time when they sleep in water, like dolphins do? Certainly no proof of that yet - but we have a method to maybe catch it. And, Yes, a human can fall asleep floating in a fluid. lnkd.in/gUHSRjug

This link will take you to a page that’s not on LinkedIn

lnkd.in

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Nat Marshall @natsleep.bsky.social · Jul 10

Cannabinoid products may reduce total sleep time in adults with insomnia: new study
theconversation.com/cannabinoid-...

Cannabinoid products may reduce total sleep time in adults with insomnia: new study

Any reduction in sleep time for people with clinical insomnia could be concerning.

theconversation.com

Nat Marshall @natsleep.bsky.social · Jun 23

There’s definately something different between bedroom temp and outdoor temperature that still has me completely scoobied pubmed.ncbi.nlm.nih.gov/26521276/

Completely scoobied: the confusing world of temperature and pollution effects on sleep apnoea - PubMed

Completely scoobied: the confusing world of temperature and pollution effects on sleep apnoea

pubmed.ncbi.nlm.nih.gov

Nat Marshall @natsleep.bsky.social · Jun 23

Fantastic analysis @bastien-lechat.bsky.social but then I'm thinking back to this pubmed.ncbi.nlm.nih.gov/22467989/

Ambient temperature and obstructive sleep apnea: effects on sleep, sleep apnea, and morning alertness - PubMed

This study is registered in ClinicalTrials.gov number NCT00544752.

pubmed.ncbi.nlm.nih.gov

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Reposted by Nat Marshall

Daniel Lakens @lakens.bsky.social · Jun 13

Venn (1866) described the problem with the "sharpshooter fallacy": 🎯 painting the bullseye on the spot where a bullet hits a door.
In psychology, we call this "HARKing" — Hypothesizing After Results Are Known.

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Nat Marshall @natsleep.bsky.social · May 26

We're going to need a bigger boat

Nat Marshall @natsleep.bsky.social · May 21

Are you assuming your audience is highly educated in the right way?

Reposted by Nat Marshall

NEJM.org @nejm.org · May 14

In the TAK-861-2001 trial involving 112 participants with narcolepsy type 1, oveporexton significantly improved measures of wakefulness, sleepiness, and cataplexy over a period of 8 weeks. Full trial results: nej.md/3ZdlKNi

#MedSky #NeuroSky

A graph showing the change from baseline in average sleep latency on the Maintenance of Wakefulness Test (MWT)

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Nat Marshall @natsleep.bsky.social · May 13

Facepalm

Darren Dahly @statsepi.bsky.social · May 8

I'm not sure we needed a statistical test here folks.

Reposted by Nat Marshall

Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · May 12

There you have it: BEDMED published in @jama.com

jamanetwork.com/journals/jam...

h/t @drjmluther.bsky.social

No difference in bedtime versus morning BP meds - as expected

#NephSky #Hypertension
1/

Figure of survival curve showing no difference

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Nat Marshall @natsleep.bsky.social · May 5

The new SPIRIT statement 2025 for how to write your clinical trial protocol www.bmj.com/content/389/...

SPIRIT 2025 explanation and elaboration: updated guideline for protocols of randomised trials

High quality protocols facilitate proper planning, conduct, reporting, and external review of randomised trials, yet their completeness varies and key elements are often not considered. To strengthen ...

www.bmj.com

Reposted by Nat Marshall

Journal of Clinical Epidemiology @jclinepi.bsky.social · Apr 17

Improving the completeness and transparency of protocols and reports of randomized trials: SPIRIT 2025 and CONSORT 2025 - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Improving the completeness and transparency of protocols and reports of randomized trials: SPIRIT 2025 and CONSORT 2025

We developed SPIRIT 2025 and CONSORT 2025 together and in a similar manner. To ascertain new evidence to inform both updates we completed two scoping reviews. The results of the scoping reviews helped...

www.jclinepi.com

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Nat Marshall @natsleep.bsky.social · Apr 17

www.nature.com/articles/d41...

New treatments to put insomnia to bed

Drugs that eliminate wakefulness, molecules in cannabis and wearable devices that modulate brain activity could help those with the condition.

www.nature.com

Reposted by Nat Marshall

JAMA @jama.com · Apr 14

Authors, editors, reviewers, and other potential users should use CONSORT 2025 when writing and evaluating manuscripts of randomized trials to ensure that trial reports are clear and transparent.

Learn more in this Special Communication. https://ja.ma/3Yyu0Hh

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Nat Marshall @natsleep.bsky.social · Apr 10

Hardly anybody has been trained to read the methods section

Reposted by Nat Marshall

The BMJ @bmj.com · Mar 25

Risk of bias assessment of randomised controlled trials has become an essential step in the systematic review process.

A new tool allows users to assess risk of bias of RCTs included in systematic reviews in a user friendly way
www.bmj.com/content/388/...

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Nat Marshall @natsleep.bsky.social · Mar 10

What role for wakefulness promotors? How well do they really work and what are the side-effects? Julia Chapman and I's latest editorial discussing the latest trial evidence authors.elsevier.com/c/1kkb52p-lG...

authors.elsevier.com

Nat Marshall @natsleep.bsky.social · Mar 5

Because you don't need a license or any training to publish 'epidemiology'?

Nat Marshall @natsleep.bsky.social · Mar 4

Do modern post-industrialised society members sleep more than hunter-gatherers? Somewhat accurately partially quoted in New Scientist. Big sample sizes don't fix the non-representative sampling problem. www.newscientist.com/article/2469...