Marc A. Marti-Renom
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mamartirenom.bsky.social
Marc A. Marti-Renom
@mamartirenom.bsky.social

Looking at genomes with 3D glasses as part of http://marciuslab.org.
President of @SCB.iec.cat
Proud member of @icreacommunity.bsky.social.
Happy at @CNAG-eu.bsky.social and @CRG.eu in Barcelona.

#4DNucleome #3Dgenomics #microbiome #biogeography .. more

Biology 80%
Medicine 9%
Pinned
Fantastic #Blutorial by our friends and colleagues at the @batllelab.bsky.social . We are so happy to collaborate with them.

@meritxellnov.bsky.social and Mireia Novell in the lab have participated in this very important piece on metastatic colorectal cancer. 👏🏼👇🏼👇🏼👇🏼

aacrjournals.org/cancerdiscov...
Several opportunities to join our group as a PhD candidate with bioinformatics or experimental background and interests in #microbiome, #Candida, or #evolution.

👉 IRB call:
www.irbbarcelona.org/en/careers/y...
👉 Inphinit call:
lacaixafoundation.org/en/doctoral-...
👉 EvoMG call
www.evomg-dn.eu

Interested in #3DGenomics #4Dnucleome? Like #Barcelona? Would like to enjoy doing #science and to have fun during your #PhD?

Apply now to La Caixa Foundation Doctoral #INPhINIT fellowships with us. DM or email in case of interest... 👇🏼👍🏼

lacaixafoundation.org/en/doctoral-...

Please, repost... 🔄🙏🏼
Doctoral INPhINIT fellowships - Incoming Call 2026
We grant 30 fellowships for researchers of any nationality who wish to pursue a doctorate in a STEM discipline at research centres of excellence in Spain or Portugal.
lacaixafoundation.org
🔬 Hot #PhD topic: Single-molecule fluorescence and super-resolution microscopy! Use quantitative nanoscale imaging to map nuclear organization. Apply by Jan 7 to join Johannes Stein’s Lab @jmstein.bsky.social & #IMPRS-BAC #gradschool!

👉 www.molgen.mpg.de/5098010/stei...
🚨 Multiple #PhD opportunities for lab or computational applicants. Do you want to understand the molecular basis of #epigenetic dysfunction in human disease?
Come work with our group at the fantastic, collaborative @uoe-igc.bsky.social in a beautiful, liveable city.
🧵 1/4
Please repost 🙏
El passat dilluns 18 de novembre, va tenir lloc l'Assamblea General Ordinària 2025 👇 #AGO
🚨 Save the date! #CNAGSymposium is coming!
🗣️ Dr. Sara Gutierrez from @vhio.bsky.social will give a talk on: “Harnessing Germline Genomics for Personalized Radiotherapy and Improved Hereditary Cancer Diagnosis”

🗓️ Tuesday, December 16th (09:00–16:30)
📝 Register here: www.cnag.eu/registration...
🧬3D genome workshop 🧬
🤩 Yesterday @jrotwitguez.bsky.social tought an awesome full day workshop on #3D #genomics to a full classroom @ucph.bsky.social
@dg.dk
🚨Reposts appreciated‼️If I had read this PhD offer five years ago, I wouldn’t have hesitated for a second to apply 😉
Passionate about gene regulation, chromatin, and developmental biology? Just contact @radaiglesiaslab.bsky.social at @ibbtec.bsky.social 🧬✨

#PhD #3DGenome
Excited to share I’ve received a #SSMF #Consolidator grant!

📣 Recruiting a #postdoc to study #cancer #neuroscience #3Dgenomics #multiomics #singlecellomics

🔬How neural inputs shape #3Dgenome and #cellplasticity in #glioblastoma #GBM

Interested? Apply now 👇
rb.gy/m7xz7b
Postdoctoral Researcher in "Cancer Neuroscience: the impact of neural activity on 3D genome organization and cellular plasticity in glioblastoma”
rb.gy
💡Un estudi liderat pels #investigadorICREA Eduard Batlle, @mamartirenom.bsky.social i Carme Cortina del @irbbarcelona.org @cnag-eu.bsky.social revela per què alguns càncers colorectals amb mutació KRAS poden esquivar els medicaments.

☝️No et perdis el fil de @batllelab.bsky.social: short.do/iLl6i4
The Batlle Lab (@batllelab.bsky.social)
🧵1/17 📣Thrilled to share our latest study just out in Cancer Discovery! ➡️ https://aacrjournals.org/cancerdiscovery/article/doi/10.1158/2159-8290.CD-25-0679/766696/A-plastic-EMP1-to-LGR5-cell-state...
short.do

I també per un altre proud @icreacommunity.bsky.social 😉😃

It was (is) a blats to work with the Batllenians… 👏🏻👇🏻👇🏻
I wrote some reflections this afternoon about how the discovery of the double helix changed the course of science. Gift link: nyti.ms/4qPS3y6

Congrats Wendy!! Good for you four and good for the field. Sure cool science ahead! 👏🏻🍾
Our lab is actively looking for posdocs and there is NOW an Open Call for Postdoc contracts (3 years) here: www.aei.gob.es/en/announcem...
www.aei.gob.es
Our lab is actively looking for PhD students and there is NOW an Open Call for PhD fellowship at the IRB Barcelona!!!!! phd.irbbarcelona.org
Application Guidelines - IRB PhD Call 2026 NOW OPEN! | Irb
phd.irbbarcelona.org
1/17 🧵
🙌Thrilled to share our first hard-core immunology paper out today in Nature Genetics! 👇

➡️We unravel how TGFβ suppresses the innate and adaptive immune system in microsatellite stable colorectal cancer (MSS CRC).

Very proud of the team and efforts behind it.

www.nature.com/articles/s41...
TGF-β builds a dual immune barrier in colorectal cancer by impairing T cell recruitment and instructing immunosuppressive SPP1+ macrophages - Nature Genetics
Targeting TGFBR1 in transplantable mouse colorectal tumor organoids improves response to anti-PD-L1 therapy. Mechanistically, TGF-β abrogates clonal expansion of T effector and memory phenotypes and i...
www.nature.com
🔬 #ColorectalCancer evades #immunotherapy using a dual barrier:

A study by #IRBBarcelona & @cnag-eu.bsky.social reveals how metastatic colorectal tumours block the immune system through two complementary mechanisms.

📰 @natgenet.nature.com

➡️ bit.ly/49BJaC0

#IRBScience @batllelab.bsky.social

🧪
We recently reported that promoter competition can contribute to the robust insulation of gene regulatory domains (www.nature.com/articles/s41...).
We now offer a 4-years PhD contract to investigate whether the dirsuption of this regulatory mechanism can lead to congenital defects. More details 👇

Great lab to do your PhD!👇🏼
OFERTA DE EMPLEO (por favor difundir):

Ofrecemos un contrato predoctoral de 4 años asociado a nuestro proyecto PID2024-157249OB-I00. El objetivo del proyecto es evaluar un nuevo mecanismo patológico según el cual la competición entre promotores puede llegar a ocasionar enfermedades congénitas
👇
OFERTA DE EMPLEO (por favor difundir):

Ofrecemos un contrato predoctoral de 4 años asociado a nuestro proyecto PID2024-157249OB-I00. El objetivo del proyecto es evaluar un nuevo mecanismo patológico según el cual la competición entre promotores puede llegar a ocasionar enfermedades congénitas
👇

Congrats Cees! Happy for all of you, what a team! 👏🏼 This is very good for our field! 🎉

A must read... at character resolution! 🤯
Our latest paper has just been published in Cell!

doi.org/10.1016/j.ce...

We developed a new method called MCC ultra, which allows 3D chromatin structure to be visualised with a 1 base pair pixel size.
Our latest paper has just been published in Cell!

doi.org/10.1016/j.ce...

We developed a new method called MCC ultra, which allows 3D chromatin structure to be visualised with a 1 base pair pixel size.
🧬 The #BGE continent-wide network behind the sequencing and assembly of these genomes includes @genoscopeumr.bsky.social opeumr.bsky.social, @cnag-eu.bsky.social u.bsky.social, @sangerinstitute.bsky.social, @scilifelab.se b.se, Università degli Studi di Firenze, and Università degli Studi di Bari.
#PCBCommunity |🧬El @batllelab.bsky.social de @irbbarcelona.org, amb @mamartirenom.bsky.social del @cnag-eu.bsky.social, descobreix que en el #càncer colorectal amb la mutació de l’oncogèn #KRAS, la pressió del tractament pot redirigir els estats cel·lulars en lloc d'eliminar-les. 🔬

👉 tuit.cat/IAkSn
Happy to share our latest publication, in which we show that the arrangement of nucleosomes around CTCF sites contributes to higher-order organisation of chromatin into TADs: www.embopress.org/doi/full/10....

I detected the discrepancy. Thanks for clarifying!! Salut Luca!

*Congrats Luca and Team!* 👏🏻BTW. In post #3 it should say seconds instead of minutes, no? 🤔