iMeta Science
@imetascience.bsky.social
96 followers
61 following
210 posts
A Wiley partner journal aims to promote metagenomics and bioinformatics by publishing research articles, reproducible methods, protocols, and reviews.
Posts
Media
Videos
Starter Packs
Pinned
iMeta Science
@imetascience.bsky.social
· Mar 20
Tidyplots empowers life scientists with easy code‐based data visualization
Effective data visualization is vital for analyzing and communicating experimental results. However, most code-based plotting tools require substantial programming experience, posing a significant ba....
onlinelibrary.wiley.com
iMeta Science
@imetascience.bsky.social
· Sep 17
Lactobacillus johnsonii‐FM1 modulates gut microbiota and secretes anticancer metabolite vanillic acid to inhibit colorectal tumorigenesis
Lactobacillus johnsonii-FM1 alleviates colorectal tumorigenesis in both ApcMin/+ and azoxymethane/dextran sulfate sodium mouse models by enriching beneficial gut microbiota, restoring epithelial barr...
onlinelibrary.wiley.com
iMeta Science
@imetascience.bsky.social
· Sep 15
fastp 1.0: An ultra‐fast all‐round tool for FASTQ data quality control and preprocessing
The figure shows side-by-side quality comparison of the data before and after preprocessing using fastp 1.0. As can be seen from this figure, the data quality has been significantly improved after fa...
onlinelibrary.wiley.com
iMeta Science
@imetascience.bsky.social
· Sep 13
Geographic containment and virulence‐resistance trade‐offs drive the evolution of hypervirulent Klebsiella pneumoniae
The global emergence of hypervirulent, carbapenem-resistant Klebsiella pneumoniae (hvCRKP) poses a paradox: why do such dangerous clones remain geographically confined? By analyzing over 2500 CC23 ge...
onlinelibrary.wiley.com
iMeta Science
@imetascience.bsky.social
· Sep 11
GISDD: A comprehensive global integrated sequence and genotyping database platform for dengue virus, facilitating a stratified coordinated surveillance strategy
GISDD, the Global Integrated Sequence and Genotyping Database for Dengue Virus (DENV), provides an integrated online analysis platform encompassing tools such as GISDDrlearn, GISDDprimer, and GISDDre...
onlinelibrary.wiley.com
iMeta Science
@imetascience.bsky.social
· Sep 11
PSOSP uncovers pervasive SOS‐independent prophages with distinct genomic and host traits in bacterial genomes
Prophages are ubiquitously present in bacterial genomes, significantly influencing host physiological and ecological functions. We present Prophage SOS-dependency Predictor (PSOSP), a novel bioinform...
onlinelibrary.wiley.com
iMeta Science
@imetascience.bsky.social
· Aug 16
Unveiling Origin Pitfalls in Metagenomic Surveillance for Emerging Infectious Diseases: Parvoviruses as a Model
A diverse reagent-associated virome, including parvoviruses, misleads zoonotic surveillance. By leveraging large language models (ChatGPT-4o), we construct a virus discovery data framework (PVDDC) an...
onlinelibrary.wiley.com
iMeta Science
@imetascience.bsky.social
· Aug 13
Discovery of a novel tetrapeptide as glucose homeostasis modulator with bifunctionalities of targeting DPP‐IV and microbiota
AI-driven and computation-based high-throughput methods were developed to mine novel dipeptidyl peptidase IV (DPP-IV) inhibitory peptides from hemp seed proteins. The identified peptide VAMP demonstr...
onlinelibrary.wiley.com
iMeta Science
@imetascience.bsky.social
· Aug 12
RRM2‐targeted nanocarrier enhances radiofrequency ablation efficacy in hepatocellular carcinoma through ferroptosis amplification and immune remodeling
This study proposes an innovative therapeutic approach by combining RRM2 gene knockout with a nanocarrier system, significantly enhancing the efficacy of radiofrequency ablation for hepatocellular ca...
onlinelibrary.wiley.com
iMeta Science
@imetascience.bsky.social
· Jul 31
Distinctive metabolic disturbances associated with redox homeostasis, nervous and hormonal functions during gut microbial enrichment upon polystyrene microplastic exposure
Microplastic-induced gut microbial enrichment was dominated by bacteria within Eubacteriales, correlated with the virome, and accompanied by colitis. The polyamine synthetic pathway was activated to ...
onlinelibrary.wiley.com
iMeta Science
@imetascience.bsky.social
· Jul 28
Gut microbial‐derived 3,4‐dihydroxyphenylacetic acid ameliorates reproductive phenotype of polycystic ovary syndrome
By integrating multi-level and multi-omics analyses, we identify 3,4-dihydroxyphenylacetic acid (DHPAA), a gut microbiota-derived degradation product of dietary flavonoids, as a key bioactive end-pro...
onlinelibrary.wiley.com
iMeta Science
@imetascience.bsky.social
· Jul 27
GitHub - mujiezhang/PSOSP: PSOSP (Prophage SOS dependency Predictor) is a novel bioinformatics tool to predict prophage induction modes by analyzing the heterology index (HI) of LexA protein binding t...
PSOSP (Prophage SOS dependency Predictor) is a novel bioinformatics tool to predict prophage induction modes by analyzing the heterology index (HI) of LexA protein binding to target DNA, classifyin...
github.com