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prelights.bsky.social
2️⃣ By blurring the line between venom and digestion, Uloboridae spiders remind us that evolution doesn’t discard complexity — it reshapes it.

#preLight + #postLight by Daniel Fernando Reyes Enríquez ⬇️👀
prelights.biologists.com/highlights/b...
Beyond venomous fangs: Uloboridae spiders have lost their venom but not their toxicity - preLights
By blurring the line between venom and digestion, Uloboridae spiders remind us that evolution doesn’t discard complexity — it reshapes it.
prelights.biologists.com
November 13, 2025 at 2:22 PM
prelights.bsky.social
How do endothelial cells differ across tissues?

🗺️ A new single-cell atlas of over 3 million cells shows how microenvironmental signals shape endothelial diversity. #preprint from Kaifu Chen & team

#preLight by Charis Qi ⬇️👀
prelights.biologists.com/highlights/h...
Human single-cell atlas analysis reveals heterogeneous endothelial signaling - preLights
How do endothelial cells differ across tissues? A new single-cell atlas of over 3 million cells shows how microenvironmental signals shape endothelial diversity.
prelights.biologists.com
November 13, 2025 at 4:08 PM
prelights.bsky.social
Do you love fashion shows?

Well, chicken’s MHC class II is an immune fashion icon that presents the same viral peptide to T cells in both a 9- and 10-amino acid outfit. 📸✨ #preprint #immunology

First solo #preLight from Mitchell Sarmie ⬇️ 👀
prelights.biologists.com/highlights/a...
A major histocompatibility complex (MHC) class II molecule that binds the same viral pathogen peptide with both nonamer and decamer core sequences for presentation to T cells - preLights
Do you love fashion shows? Well, chicken’s MHC class II is an immune fashion icon that presents the same viral peptide to T cells in both a 9- and 10-amino acid outfit.
prelights.biologists.com
November 10, 2025 at 4:11 PM
prelights.bsky.social
Biological conduction bridges skip a beat. ❤️

#preLight (from Theodora Stougiannou) of a study generating stem-cell derived AVN-like pacemaker cells + demonstrating their functionality for biological conduction bridge applications in vivo. @uhnresearch.ca
prelights.biologists.com/highlights/h...
Human pluripotent stem cell-derived atrioventricular node-like pacemaker cells exhibit biological conduction bridge properties in vitro and in vivo - preLights
Biological conduction bridges skip a beat. The preprint authors generate AV node-like pacemaker cells from human pluripotent stem cell populations in order to create a biological conduction bridge.
prelights.biologists.com
October 29, 2025 at 3:16 PM
prelights.bsky.social
The 2nd preLight in this series is written by
@andreamorimc.bsky.social

The #preprint covered investigates signalling pathways involved in cell migration, amoeboid movement & osteoclast activation + relevant for breast cancer metastasis treatment
#preLight⬇️
prelights.biologists.com/highlights/t...
TAM receptors control actomyosin dynamics in osteoclasts via RHOA-COFILIN-MYOSIN II signaling - preLights
This preprint investigates the RHOA-ROCK and COFILIN pathways involved in cell migration, amoeboid movement and osteoclast activation and useful to address in breast cancer bone metastasis treatment.
prelights.biologists.com
October 17, 2025 at 1:28 PM
prelights.bsky.social
Turning back the clock on stem cells. 🕒

Did you see the preLight @vibhasingh.bsky.social posted last week highlighting the #preprint of Eva Mejía-Ramírez & team?

#preLight: prelights.biologists.com/highlights/t...

This work was also discussed in a recent webinar ⬇️👀
September 30, 2025 at 10:18 AM
carrier-media.co.uk
I love a prelight day.

Bloody Hell Keith, don't you have any trousers?
Image is Lego Pete Carrier with drill in hand standing in front of a series of platforms. On one platform a lady stands, laughing between sips from a pink mug. Above her on another platform stands Keith the Rigger, in what appear to be Olympic Speedos
September 9, 2024 at 11:20 AM
prelights.bsky.social
Stretch it, wound it, pull it: ADIP-Diversin polarizes anyway. Characterization of a new mechanosensitive polarity module 🐸

First #preLight from @alinegrata.bsky.social, highlighting #preprint from Chih-Wen Chu, Satheeja Velayudhan, Sergei Sokol and team:
prelights.biologists.com/highlights/m...
Mechanical cues organize planar cell polarity during vertebrate morphogenesis and embryonic wound repair - preLights
Stretch it, wound it, pull it: ADIP-Diversin polarizes anyway. Characterization of a new mechanosensitive polarity module.
prelights.biologists.com
July 4, 2025 at 7:51 AM
candynr.bsky.social
Unravelling the unraveller: novel protein-protein interactions and regulatory networks of regulatory protein HNRPNU. This preprint was really interesting to uncover and read about in this prelight.
prelights.biologists.com/highlights/m...
Molecular interactome of HNRNPU reveals regulatory networks in neuronal differentiation and DNA methylation - preLights
Unraveling the unraveller: novel protein-protein interactions and roles of regulatory protein HNRNPU.
prelights.biologists.com
June 25, 2025 at 4:18 PM
prelights.bsky.social
ISR alone won’t cut it: stalled ribosomes block stress granule formation despite ISR activation.

Mohammed Jalloh highlights a #preprint from the Moon lab.

#preLight ⬇️👀
prelights.biologists.com/highlights/t...

#translation #MolecularBiology #biochemistry
tRNA synthetase activity is required for stress granule and P-body assembly - preLights
ISR alone won’t cut it: stalled ribosomes block stress granule formation despite ISR activation.
prelights.biologists.com
May 20, 2025 at 10:41 AM
prelights.bsky.social
Two new #postLights are out!

1️⃣ @mohjalloh.bsky.social revisits a #preLight on how mRNA localization to P-bodies depends on the cell cycle—work now published in #MolecularCell.

What’s changed, what held up, and what was added? Read the comparison ⬇️
prelights.biologists.com/highlights/c...
Cell cycle-dependent mRNA localization in P-bodies - preLights
P-bodies are more than just storage sites for translationally repressed mRNAs and RNPs
prelights.biologists.com
May 30, 2025 at 9:25 AM
prelights.bsky.social
Unraveling the unraveller: novel protein-protein interactions and roles of regulatory protein HNRNPU.

#preLight prepared by Candy Rutihinda, R Bibata Ouédraogo and Bryce Rampal⬇️ 👀 #uMontreal
@umontreal.ca

prelights.biologists.com/highlights/m...
Molecular interactome of HNRNPU reveals regulatory networks in neuronal differentiation and DNA methylation - preLights
Unraveling the unraveller: novel protein-protein interactions and roles of regulatory protein HNRNPU.
prelights.biologists.com
June 27, 2025 at 9:52 AM
prelights.bsky.social
Mass extinction can be detected in phylogenetic trees that have been estimated using flawed methodologies.

@tomacarruthers.bsky.social discusses a #preprint from Minghao Du & team @ibensens.bsky.social

#evolution #paleontology

#preLight ⬇️
prelights.biologists.com/highlights/e...
Evaluating the impact and detectability of mass extinctions on total-evidence dating - preLights
Mass extinction can be detected in phylogenetic trees that have been estimated using flawed methodologies.
prelights.biologists.com
November 10, 2025 at 3:56 PM
fadelvalle.bsky.social
Happy to share my latest preLight !
January 6, 2025 at 11:35 AM
biologists.bsky.social
We are featuring Amanda Haage as an extraordinary biologist this week. Amanda was the first to post on @prelights.bsky.social and is a Kaess Endowed Professor of Anatomy & Cell Biology at the University of North Dakota, USA. #100biologists
The Company of Biologists 100 logo to the left and QR code to the right. Portrait of Amanda Haage to the left, text to the right 100 extraordinary biologists Amanda Haage Amanda Haage posted the first preLight in 2018 and set an example for others to follow. She advocates for academic cultural change and is a KaessEndowed Professor of Anatomy & Cell Biology at the University of North Dakota, USA. #100biologists #biologists100
March 18, 2025 at 12:01 PM
carrier-media.co.uk
I love a prelight day.
Lego Pete Carrier standing in a studio space holding a spanner. In the back ground a number of sections of black truss stand partly erected.
June 28, 2025 at 9:14 AM
kiransoma.bsky.social
Thank you! I love the preLight idea.
August 4, 2025 at 2:11 AM
prelights.bsky.social
Introducing an “identifiability-guided assessment” framework & applying it to longitudinal Alzheimer’s datasets. 🧠

My Nguyen highlights important work from Juliet Jiang & team #ADNI3study

#neuroscience #preLight ⬇️

prelights.biologists.com/highlights/i...
Identifiability-Guided Assessment of Digital Twins in Alzheimer’s Disease Clinical Research and Care - preLights
The authors present an “identifiability-guided assessment” framework—a new approach to pinpoint which parameters in a personalized digital twin model can be confidently trusted.
prelights.biologists.com
November 11, 2025 at 12:39 PM
prelights.bsky.social
Hyaluronic acid deposition & a soft ECM promote digit regeneration in mice. 🐁

@jontytownson.bsky.social covers the first #preprint from the @storerlab.bsky.social delving into the importance of the ECM in wound regeneration in mice.

#preLight ⬇️ 👀
prelights.biologists.com/highlights/h...
Hyaluronic Acid and Emergent Tissue Mechanics Orchestrate Digit Tip Regeneration - preLights
Mui and team show hyaluronic acid deposition and a soft ECM promote digit regeneration in mice.
prelights.biologists.com
March 21, 2025 at 12:32 PM
franzelab.bsky.social
Thanks for picking our preprint and for this very nice prelight article!
dev-journal.bsky.social Development @dev-journal.bsky.social · Jun 19
In preprints: unpicking chemical and mechanical crosstalk for axonal pathfinding

Dionn Hargreaves and Sarah Woolner @mcrcellmatrix.bsky.social‬ discuss the #preprint from @evapillai.bsky.social‬ ‪@sudimukherjee.bsky.social‬ @franzelab.bsky.social‬ et al.
journals.biologists.com/dev/article/...
In preprints: a new preprint curation initiative from Development
June 19, 2025 at 10:06 AM
prelights.bsky.social
Shaping the postnatal brain - how the grooves of our brain continue to develop after birth.

A new #SciArt #preLight features graphical abstracts by Jeny Jose and Jawdat Sandakly. It highlights the work of Sarah Tung, Vaidehi Natu and @kalanitgs.bsky.social 's research group.
How infant brains fold: Sulcal deepening is linked to development of sulcal span, thickness, curvature, and microstructure - preLights
Shaping the postnatal brain - how the grooves of our brain continue to develop after birth.
prelights.biologists.com
July 15, 2025 at 1:48 PM
prelights.bsky.social
No road? No problem! Squeezing through cell tunnels helps leukocytes reach target sites. 🚇

@fadelvalle.bsky.social covers a #preprint revealing a previously unrecognised level of complexity in leukocyte trafficking. @joachimgoedhart.bsky.social

#preLight ⬇️
prelights.biologists.com/highlights/l...
Leukocytes use endothelial membrane tunnels to extravasate the vasculature - preLights
No road? No problem ! Squeezing through cell tunnels helps leukocytes reach their target sites
prelights.biologists.com
December 9, 2024 at 10:55 AM
richardhowe.bsky.social
The prelight for the photoshoot is running behind schedule, but that allowed me to meet and work with our propmaster, Gillis. One of my favorite things in the world is meeting very talented people and seeing them work their magic. Probably the most fun I've had at my job in a few months.
August 30, 2024 at 7:28 PM
prelights.bsky.social
Marmosets display unique subtypes of trigeminal ganglia (TG) neurons.

Vanessa Ehlers highlights a study from Karen A Lindquist & colleagues in which they characterise mechanical responses in TG neurons from common marmosets. #preprint

Read the #preLight! ⬇️👀
prelights.biologists.com/highlights/i...
Investigating Mechanically Activated Currents from Trigeminal Neurons of Non-Human Primates - preLights
Marmosets display unique subtypes of trigeminal ganglia neurons: implications for normal somatosensory function and pain
prelights.biologists.com
December 5, 2024 at 10:49 AM
1tacblue.bsky.social
* * * ** * [Prelight) A note which helps when talking by asking (a-s. 'Monsana with Aged Man
* * * ** * [Prelight) A note which helps when talking by asking (a-s. 'Monsana with Aged Man
September 12, 2025 at 1:43 PM