We loved hearing @khammerschmidt.bsky.social talk about evolution at the #MultiBac2025 conference this January - check out the @asm.org report on the origins of early microbial life!
Happy to have been part of EVOLUTION & MECHANISMS GOVERNING MULTICELLULARITY—one of 3 workshops behind @asm.org’s new report. Big questions, great conversations—looking back on origins of microbial life and what lies ahead. Highly recommended read: asm.org/reports/earl...
#MicroSky #MEvoSky #EvoSky
#MicroSky #MEvoSky #EvoSky
June 24, 2025 at 9:04 AM
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February 1, 2025 at 8:38 PM
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It was fun talking about this project at a conference - I think for the first time - and a pleasure to give the very last talk at #MultiBac2025. I learned so much about multicellular bacterial systems at this meeting and take home a number of ideas and concepts.
Last talk at #MultiBac2025 by Wolfram Möbius - The hunt for the microscopic origin of macroscopic chirality in E. coli colonies
About 10 year collaboration with K.C. Huang
About 10 year collaboration with K.C. Huang
January 10, 2025 at 8:15 AM
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Thanks for ending this great conference with such a stimulating, thought-provoking talk @wolframmoebius.bsky.social
#MultiBac2025
#MultiBac2025
Last talk at #MultiBac2025 by Wolfram Möbius - The hunt for the microscopic origin of macroscopic chirality in E. coli colonies
About 10 year collaboration with K.C. Huang
About 10 year collaboration with K.C. Huang
January 9, 2025 at 1:59 PM
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Wolfram on chirality in E.coli colonies, see their #mBio paper
journals.asm.org/doi/10.1128/...
but also referring to Liselotte Jauffred et al #ISMEJournal on mutants and chirality
www.nature.com/articles/ism...
#MultiBac2025
journals.asm.org/doi/10.1128/...
but also referring to Liselotte Jauffred et al #ISMEJournal on mutants and chirality
www.nature.com/articles/ism...
#MultiBac2025
Bacterial Filamentation Drives Colony Chirality | mBio
Chiral objects, such as amino acids, are distinguishable from their mirror image.
For living systems, the fundamental mechanisms relating cellular handedness to chirality
at the multicellular scale re...
journals.asm.org
January 9, 2025 at 11:47 AM
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Last talk at #MultiBac2025 by Wolfram Möbius - The hunt for the microscopic origin of macroscopic chirality in E. coli colonies
About 10 year collaboration with K.C. Huang
About 10 year collaboration with K.C. Huang
January 9, 2025 at 11:36 AM
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Poster prizes at #MultiBac2025 1st International Conference on Emergent Functions of Bacterial Multicellularity of SPP2389 were awarded to Ruth Viveros (Tschowri lab), Miriam Epping (Grünberger lab), Danielle Gabi Lange (Dar lab)
-sponsored by @molecularmicro.bsky.social and Curr Opin Microbiol
-sponsored by @molecularmicro.bsky.social and Curr Opin Microbiol
January 9, 2025 at 11:26 AM
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Berenike Maier - Membrane potential dynamics in bacterial colonies
#gonococcal_colonies #membrane_potential #protons
#MultiBac2025
#gonococcal_colonies #membrane_potential #protons
#MultiBac2025
January 9, 2025 at 11:17 AM
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See the work of Marlis presented today in bioRxiv:
www.biorxiv.org/content/10.1...
Published version coming soon...
#MultiBac2025
www.biorxiv.org/content/10.1...
Published version coming soon...
#MultiBac2025
Spatial population dynamics of bacterial colonies with social antibiotic resistance
Bacteria frequently inhabit surface-attached communities where rich “social” interactions can significantly alter their population-level behavior, including their response to antibiotics. Understandin...
www.biorxiv.org
January 9, 2025 at 11:11 AM
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Marlis Denk-Lobnig @marlis.bsky.social on Spatial organization of bacterial colonies with social antibiotic resistance
#MultiBac2025
#MultiBac2025
January 9, 2025 at 10:56 AM
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Gürol mentiones their upcoming conference: WINTER Q-BIO
with @francesarnold.bsky.social and @doudna-lab.bsky.social
Everything about quantitative biology on this conference in Hawaii
#MultiBac2025
with @francesarnold.bsky.social and @doudna-lab.bsky.social
Everything about quantitative biology on this conference in Hawaii
#MultiBac2025
January 9, 2025 at 10:52 AM
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Gürol also highlights their work on Mg+, K+, ribosomes, and antibiotic resistance
see their recent Science Advances paper
www.science.org/doi/full/10....
#MultiBac2025
see their recent Science Advances paper
www.science.org/doi/full/10....
#MultiBac2025
Physiological cost of antibiotic resistance: Insights from a ribosome variant in bacteria
A resistant bacterial ribosome variant is outcompeted despite antibiotic pressure when Mg2+ is limited, exposing a vulnerability.
www.science.org
January 9, 2025 at 10:46 AM
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Gürol explains that they can have a strong effect of electrical stimulations at pH5.0 on skin bacteria (note, the skin pH is around 5) - thus narrow proton gradient range induces selective stimulation
See their paper in Device:
www.cell.com/device/fullt...
#MultiBac2025
See their paper in Device:
www.cell.com/device/fullt...
#MultiBac2025
Bioelectronic drug-free control of opportunistic pathogens through selective excitability
Staphylococcus epidermidis is a skin-dwelling bacterium responsible for common clinical infections. In this study, we discovered that S. epidermidis becomes electrically excitable when exposed to the acidic pH of healthy skin. This excitability enables antibiotics-free, bioelectronic suppression of the opportunistic pathogen using mild stimulation conditions.
www.cell.com
January 9, 2025 at 10:42 AM
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Gürol on manipulating K+ to regulate cell type signaling
See their recent paper on methodology
link.springer.com/article/10.1...
Photo on a Bacillus colony from below with ioinc control device
#MultiBac2025
See their recent paper on methodology
link.springer.com/article/10.1...
Photo on a Bacillus colony from below with ioinc control device
#MultiBac2025
January 9, 2025 at 10:36 AM
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Gürol exaplains their works started about 10 years ago about action potential spread in B. subtilis colonies
#MultiBac2025
#MultiBac2025
January 9, 2025 at 10:24 AM
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Gürol highlights that ions are the second most abundant in a living cell after water 🤔
Ions are involved in regulating emerging functions in cells, for example ion channels (K ion channel) in brain function and Bacillus development
#MultiBac2025
Ions are involved in regulating emerging functions in cells, for example ion channels (K ion channel) in brain function and Bacillus development
#MultiBac2025
January 9, 2025 at 10:22 AM
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Last session of #MultiBac2025 with a plenary by Gürol M. Süel
Charge matters: Ionic conversations and competitions
Charge matters: Ionic conversations and competitions
January 9, 2025 at 10:16 AM
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Stephan Wimmi (Berenike Maier group) on Inside-out: Remodeling of gonococcal microcolonies due to changing pili interaction network
#MultiBac2025
#MultiBac2025
January 9, 2025 at 9:32 AM
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Kerstin Thriene @kerstinthriene.bsky.social (Kai Papenfort lab @uni-jena.de) on Increased antibiotic resistance in Vibrio cholerae biofilms on microplastics is attributed to the plastic additive BPA
#MultiBac2025
#MultiBac2025
January 9, 2025 at 9:10 AM
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Niclas Nordholt - Phenotypic heterogeneity in bacterial lag times and antibiotic tolerance induced by the disinfectant glutaraldehyde
Introduction to biocides and their influence on/connection to antibiotic tolerance
#MultiBac2025
Introduction to biocides and their influence on/connection to antibiotic tolerance
#MultiBac2025
January 9, 2025 at 8:49 AM
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Tam finishes on their ecological exploration of Myxococcous habitat, and correlation of specific fungal partner with Myxococcus, validated by laboratory interaction between the two
[Cell biologist turning into ecologist 🤔]
#MultiBac2025
[Cell biologist turning into ecologist 🤔]
#MultiBac2025
January 9, 2025 at 8:43 AM
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Tam tells us an amazing molecular cell biology dissection of contact dependent killing identifying the components of pili with exchangable tips that have difffeent efficiency depending on the prey species
mindblowing detailed insights 😲
#MultiBac2025
mindblowing detailed insights 😲
#MultiBac2025
January 9, 2025 at 8:37 AM
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Tam shows us amazing time-lapse videos how A-motile cells of Myxococcus kill E.coli prey cells in a contact dependent manner
kilACF mutant unable to kill the prey cells in spite of invading the colony, see their @elife.bsky.social paper:
elifesciences.org/articles/724...
#MultiBac2025
kilACF mutant unable to kill the prey cells in spite of invading the colony, see their @elife.bsky.social paper:
elifesciences.org/articles/724...
#MultiBac2025
A Tad-like apparatus is required for contact-dependent prey killing in predatory social bacteria
elifesciences.org
January 9, 2025 at 8:15 AM
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Tam Mignot - Predatory soil bacteria: from molecular and cellular scales to ecology
#Mycobacteria #PredatoryBacteria #Imaging
#MultiBac2025
#Mycobacteria #PredatoryBacteria #Imaging
#MultiBac2025
January 9, 2025 at 8:04 AM
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Thank you to Ákos for allowing those of unable to make the trip to follow along this (sold out!) conference on Emergent Functions of Bacterial Multicellularity.
#SPP2389. #MultiBac2025
Molecular Microbiology is pleased to be able to sponsor a poster prize and support this amazing community!
#SPP2389. #MultiBac2025
Molecular Microbiology is pleased to be able to sponsor a poster prize and support this amazing community!
January 8, 2025 at 7:09 PM
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