#JLipidRes:
No. 9 on ASBMB Today's 2025 most-read list: Butter, olive oil or coconut oil — what’s the healthiest choice?

Researchers at @mrcepid.bsky.social analyzed how various types of dietary fats may impact the health of adults and published their results in #JLipidRes: www.asbmb.org/asbmb-....
Butter, olive oil, coconut oil — what to choose?
Depending on the chain length and origin of the fat, regular fat consumption changes the specific makeup of fats in bloodstream and affect mild to severe cholesterol patterns. Read about this recent Journal of Lipid Research study.
www.asbmb.org
December 22, 2025 at 2:46 PM
At the #JLipidRes session on #lipids in cell communication and metabolism, speakers will share new insights into signaling, inflammation, immunity and metabolic disease.
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☑️ Late-breaking abstracts open soon!
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#ASBMB26 #MakeItPossible
November 25, 2025 at 3:05 AM
New in JLR press| Chronic Kidney Disease Induces Distinct Alterations of Macrophage Lipid Metabolism in a Mouse Model of Atherosclerosis.
Learn more:
www.jlr.org/article/...
#jlipidres
January 20, 2026 at 3:32 PM
New in JLR press| Scientists' study aimed to elucidate the metabolic profiles of plasma ceramides and glycosphingolipids (GSLs) in Parkinson's disease patients.
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www.jlr.org/article/...
#jlipidres
December 9, 2025 at 7:27 PM
An integrative approach to studying sphingolipid metabolism reveals p53 as a master regulator of the pathway. #JLipidRes #MassSpec www.jlr.org/article/S002...
An integrative approach to studying sphingolipid metabolism reveals p53 as a master regulator of the pathway.
Sphingolipids (SPLs) are bioactive lipids playing vital functions in cellular stress responses. The tumor suppressor p53 has been implicated in regulating few specific SPL enzymes; however, a comprehe...
www.jlr.org
February 4, 2026 at 7:44 PM
In a recent study in Journal of Lipid Research, scientists used a new imaging approach to map fentanyl’s effects on brain immune cells. Their findings could transform how addiction is assessed and lead to new diagnostic and therapeutic tools: www.asbmb.org/asbmb-today/.... #ASBMBJournals #JLipidRes
Mapping fentanyl’s cellular footprint
Using a new imaging method, researchers at State University of New York at Buffalo traced fentanyl’s effects inside brain immune cells, revealing how the drug alters lipid droplets, pointing to new pa...
www.asbmb.org
December 5, 2025 at 6:04 PM
Dysregulated metabolism of ceramides and glycosphingolipids in Parkinson’s Disease #JLipidRes #MassSpec www.jlr.org/article/S002...
Dysregulated metabolism of ceramides and glycosphingolipids in Parkinson’s Disease
Alterations in sphingolipid metabolism have been implicated in the pathogenesis of Parkinson's disease (PD), yet findings regarding peripheral sphingolipid changes remain inconsistent. This study aime...
www.jlr.org
December 6, 2025 at 12:11 PM
Spatial and Temporal Brain Biodistribution of Neuropathogenic Sphingolipids of Krabbe Disease #JLipidRes #MassSpec www.jlr.org/article/S002...
Spatial and Temporal Brain Biodistribution of Neuropathogenic Sphingolipids of Krabbe Disease
Glycosphingolipids are essential lipids enriched in the outer leaflet of the plasma membrane, particularly those forming the myelin sheaths. Disorders impacting the glycosphingolipid metabolism cause ...
www.jlr.org
December 6, 2025 at 12:12 PM
The n-3 PUFA content of the global lipidomes of NIST SRM 2378, SRM 1950 and intra-laboratory quality control materials #JLipidRes #MassSpec www.jlr.org/article/S002...
The n-3 PUFA content of the global lipidomes of NIST SRM 2378, SRM 1950 and intra-laboratory quality control materials
The regular use of commercially available Standard Reference Materials (SRM) and intra-laboratory quality control (ILQC) materials are important tools for standardizing and ensuring high quality lipid...
www.jlr.org
December 27, 2025 at 9:02 PM
Circulating lipidome underpins gender differences in the pathogenesis of type 2 diabetes #JLipidRes #MassSpec www.jlr.org/article/S002...
Circulating lipidome underpins gender differences in the pathogenesis of type 2 diabetes
Metabolic alterations in human lipidome significantly impact various chronic diseases including type 2 diabetes (T2D). However, epidemiology and clinical studies have yet to identify clinically meanin...
www.jlr.org
April 27, 2025 at 8:25 AM
Orm2 promotes nitrogen-induced sphingolipid production and endocytosis via Orm1 phosphorylation #JLipidRes #MassSpec www.jlr.org/article/S002...
Orm2 promotes nitrogen-induced sphingolipid production and endocytosis via Orm1 phosphorylation
The Orm family proteins inhibits serine palmitoyltransferase —the enzyme that catalyzes the first step in sphingolipid synthesis. In S. cerevisiae, the two Orm proteins are thought to function redunda...
www.jlr.org
October 8, 2025 at 9:05 AM
New in JLR press| Scientists' findings suggest that 17,18-EpETE has potential as a supplementary agent to mitigate inflammatory side effects.
Learn more:
www.jlr.org/article/...
#jlipidres
December 30, 2025 at 10:51 PM
Development and application of an LC-MS/MS method for the combined quantification of oxysterols and bile acids #JLipidRes www.jlr.org/article/S002...
Development and application of an LC-MS/MS method for the combined quantification of oxysterols and bile acids
Oxysterols and bile acids are interconnected bioactive lipids playing pivotal roles in diverse physiological and pathological processes. For this reason, they are increasingly studied together for the...
www.jlr.org
November 18, 2024 at 11:18 AM
Integrated lipidomic and proteomic profiling reveals metabolic network disruption by SARS-CoV-2 variants #JLipidRes #MassSpec www.jlr.org/article/S002...
Integrated lipidomic and proteomic profiling reveals metabolic network disruption by SARS-CoV-2 variants
The rapid evolution of SARS-CoV-2 has produced myriad viral strains with increasing transmissibility and capacity for immune evasion. While effective vaccination campaigns have reduced the fatalities ...
www.jlr.org
July 13, 2025 at 3:41 PM
Clinical Lipidomics Reveals High Individuality and Sex Specificity of Circulatory Lipid Signatures: A Prospective Healthy Population Study #JLipidRes #MassSpec www.jlr.org/article/S002...
Clinical Lipidomics Reveals High Individuality and Sex Specificity of Circulatory Lipid Signatures: A Prospective Healthy Population Study
Lipid metabolism and circulatory lipid levels are tightly associated with the (cardio)metabolic health. Consequently, mass spectrometry (MS)-based lipidomics has emerged as a powerful phenotyping tool...
www.jlr.org
March 18, 2025 at 6:57 PM
In a recent study in Journal of Lipid Research, scientists used a new imaging approach to map fentanyl’s effects on brain immune cells. Their findings could transform how addiction is assessed and lead to new diagnostic and therapeutic tools: www.asbmb.org/asbmb-.... #ASBMBJournals #JlipidRes
Mapping fentanyl’s cellular footprint
Using a new imaging method, researchers at State University of New York at Buffalo traced fentanyl’s effects inside brain immune cells, revealing how the drug alters lipid droplets, pointing to new paths for addiction diagnostics.
www.asbmb.org
December 5, 2025 at 6:03 PM
Characterization of the brain lipidome associated with frontotemporal lobar degeneration MAPT P301S mutation #JLipidRes #MassSpec www.jlr.org/article/S002...
Characterization of the brain lipidome associated with frontotemporal lobar degeneration MAPT P301S mutation
Mutations in microtubule-associated protein Tau (MAPT), the gene that codes for the protein Tau, cause frontotemporal lobar degeneration (FTLD) with phenotypes ranging from behavioral changes to cogni...
www.jlr.org
November 28, 2025 at 9:06 PM
Multi-omics analysis to evaluate the enrichment of extracellular vesicles from human plasma #JLipidRes #MassSpec www.jlr.org/article/S002...
Multi-omics analysis to evaluate the enrichment of extracellular vesicles from human plasma
Extracellular vesicles (EVs) in blood plasma offer a valuable reservoir of intracellular cellular cargo, making them a promising source of liquid-based biomarkers. However, the complexity of plasma, w...
www.jlr.org
August 19, 2025 at 12:51 PM
Plasma lipidomics and 15-year risk of incident diabetes: A Coronary Artery Risk Development in Young Adults Study #JLipidRes #MassSpec www.jlr.org/article/S002...
Plasma lipidomics and 15-year risk of incident diabetes: A Coronary Artery Risk Development in Young Adults Study
Lipid metabolism has long been implicated in diabetes, but there has been a paucity of population-based studies of the plasma lipidome and incident diabetes in cohorts of early-middle age. We used dat...
www.jlr.org
January 31, 2026 at 9:56 PM
Mass Spectrometry Imaging of Adipose Tissue Lipidome Maps Lineage-Specific Metabolite Profiles #JLipidRes www.jlr.org/article/S002...
Mass Spectrometry Imaging of Adipose Tissue Lipidome Maps Lineage-Specific Metabolite Profiles
Adipocyte subtypes may drive a heterogeneous distribution of lipids in adipose tissue. Adipocytes from the transient receptor potential cation channel subfamily V member 1 (Trpv1) lineage are one such...
www.jlr.org
January 20, 2026 at 12:16 PM
New in JLR press| Scientists' results showed that in vitro, asprosin reduced expression of lipogenic genes and increased those of fatty acid oxidation and mitochondrial activity in hepatocytes.
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www.jlr.org/article/...
#jlipidres
November 4, 2025 at 7:20 PM
Today, Dr. Cyrille Botte and the @ApicoLipid Lab (@ParaFrap team) is running the #LipidTakeover on @jlipidres Twitter account. Join them as they discuss membrane biogenesis, metabolism of infectious parasitic diseases and more! (US EST Time 9am-5pm / CEST 3pm-11pm

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December 19, 2024 at 4:49 PM
This #JLipidRes cover shows RAW264.7 cells, treated with lipopolysaccharide and stained with DAPI, apoA1, LAMP1, a marker of lysosomes.

Delve into the paper "HDL attenuates LPS-induced inflammation via SR-B1-mediated lysosomal degradation" by Deng, Haoyu et al.: www.jlr.org/article/....
December 14, 2025 at 12:32 PM