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haoyin.bsky.social
Hao Yin
@haoyin.bsky.social
#Fumarate update

Gang of 3: How the Krebs cycle-linked metabolites itaconate, succinate, and fumarate regulate macrophages & inflammation

Dual role in Inflammation

Anti-
KEAP1-NRF2
GSDMD
NLRP3
IL-10

Pro-
mtDNA mtRNA➡️IFNβ

#CellMetab 2025
www.sciencedirect.com/science/arti...
June 21, 2025 at 7:47 PM Everybody can reply
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realbiomassspec.bsky.social
BioMassSpec
@realbiomassspec.bsky.social
Circulating glycerate predicts resilience to fructose-induced hepatic steatosis #CellMetab #MasssSpec www.sciencedirect.com/science/arti...
Circulating glycerate predicts resilience to fructose-induced hepatic steatosis
Excessive intake of dietary fructose increases the risk of metabolic-dysfunction-associated steatotic liver disease (MASLD), cirrhosis, and cancers. H…
www.sciencedirect.com
April 24, 2025 at 1:22 PM Everybody can reply
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sharonblady.bsky.social
Sharon Blady⁷
@sharonblady.bsky.social
#Diabetes #CellMetab #Medsky
bcellorg.bsky.social Patrick MacDonald🇨🇦 @bcellorg.bsky.social · Jan 10
Re-upping this paper which is ‘out’ now in this month’s issue of Cell Metab. Working with a fantastic group of collaborators, we provide a resource for exploring human islet variation in health and diabetes.

https://www.cell.com/cell-metabolism/fulltext/S1550-4131(24)00365-6
January 10, 2025 at 7:41 PM Everybody can reply
haoyin.bsky.social
Hao Yin
@haoyin.bsky.social
Always have a plan B🤠

Two Parallel Cascades of Adipocytic Thermogenesis in adult🐭
UCP1+Creatine Kinase B

Unlike germline Ucp1 KO, adult #BrownAdiposeTissue Ucp1 KO▶️No defects in Adipocytic Thermogenesis

Adipocyte UCP1/CKB dKO▶️80% Hypothermia

#CellMetab 2024
www.sciencedirect.com/science/arti...
February 3, 2024 at 8:41 PM Everybody can reply
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