We report on a rare case of Aggregatibacter aphrophilus brain abscess of odontogenic origin in a 6-year-old previously healthy boy, who had close cont…

#MicroRounds (Day 386): Probably common, but rare to see (it's fastidious) Aggregatibacter aphrophilus ('A' in HACEK endocarditis organisms). Causes endocarditis, periodontal disease. This isolate: from brain tissue! Among HACEK orgs unique bc catalase negative #ASMClinMicro https://t.co/zEAUXIg0Kh

Introduzione: Aggregatibacter actinomycetemcomitans – Un Periopatogeno Chiave Sotto Esame Aggregatibacter actinomycetemcomitans (A. actinomycetemcomitans) è un batterio Gram-negativo, immobile, tradizionalmente riconosciuto come un periopatogeno significativo, particolarmente associato a forme aggressive di parodontite, soprattutto in adolescenti e giovani adulti. La sua capacità di colonizzare l'ambiente orale e di esercitare effetti patogeni lo rende un soggetto di continuo studio nella ricerca parodontale. Nonostante la parodontite sia una malattia multifattoriale, con una complessa interazione tra fattori ambientali, genetici e microbici, A.

Aim: The aim of the current investigation was to detect serotypes of Aggregatibacter actinomycetemcomitans in a cohort of Western Australians diagnosed with periodontitis. Materials and Methods: A total of 64 subjects were selected. Intra-oral samples were taken from every subject in the present investigation. Periodontal, radiographical, and microbiological analyses were conducted. A polymerase chain reaction was employed to investigate the presence of Aggregatibacter actinomycetemcomitans serotypes. Results: Only twelve (18.75%) patients were tested positive for Aggregatibacter actinomycetemcomitans. The most dominant serotypes of Aggregatibacter actinomycetemcomitans in this group were serotype e (80.55%), followed by serotype c (52.77%). Both serotypes b and d were absent in the present investigation. Serotype e presented in isolation or combined with other serotypes. The other serotypes tend to be present alone, but when they were isolated together, they were always combined with serotype e. It seems that serotype e of Aggregatibacter actinomycetemcomitans is associated with those who live in rural areas (p = 0.003), and those with low education (p = 0.041), and severe forms of periodontitis in this cohort. Conclusions: In patients diagnosed with severe periodontitis, serotype e was dominant in this population. Serotypes b and d did not appear in the present study.

Aim: The aim of the current investigation was to detect serotypes of Aggregatibacter actinomycetemcomitans in a cohort of Western Australians diagnosed with periodontitis. Materials and Methods: A total of 64 subjects were selected. Intra-oral samples were taken from every subject in the present investigation. Periodontal, radiographical, and microbiological analyses were conducted. A polymerase chain reaction was employed to investigate the presence of Aggregatibacter actinomycetemcomitans serotypes. Results: Only twelve (18.75%) patients were tested positive for Aggregatibacter actinomycetemcomitans. The most dominant serotypes of Aggregatibacter actinomycetemcomitans in this group were serotype e (80.55%), followed by serotype c (52.77%). Both serotypes b and d were absent in the present investigation. Serotype e presented in isolation or combined with other serotypes. The other serotypes tend to be present alone, but when they were isolated together, they were always combined with serotype e. It seems that serotype e of Aggregatibacter actinomycetemcomitans is associated with those who live in rural areas (p = 0.003), and those with low education (p = 0.041), and severe forms of periodontitis in this cohort. Conclusions: In patients diagnosed with severe periodontitis, serotype e was dominant in this population. Serotypes b and d did not appear in the present study.

Abstract. We report a case of brain and lung abscesses caused by Agreggatibacter aphrophilus in a 43-YEAR-OLD man with past history of splenectomy and drug

A 42-year-old man with no past medical history presented with 3 days of nonlocalizing headache and confusion. The patient had been writing nonsensical e-mails and his speech content was altered. The p...