Zach Rosenthal
@zachrosenthal.bsky.social
👨⚕️ PGY4 psychiatry resident @ Penn Med, ⚡️🧠 neuroscientist postdoc and 🌈 🏔 human person. Previously WashU MSTP, Haverford College, and Scribbles Pre-school. Views my own.
Why has this gone undetected for nearly 86 years? CSD wavefronts travel very slowly (millimeters per minute), such that when they are subjected to routine low frequency EEG filtering (our mainstay tool for brain monitoring during ECT), they’re rendered virtually invisible (right video panel).
May 18, 2025 at 6:03 PM
Why has this gone undetected for nearly 86 years? CSD wavefronts travel very slowly (millimeters per minute), such that when they are subjected to routine low frequency EEG filtering (our mainstay tool for brain monitoring during ECT), they’re rendered virtually invisible (right video panel).
In a mouse model, we observed that seizure is followed by a slow-traveling wave of maximal neural and hemodynamic activation followed by suppression, consistent with cortical spreading depolarization (CSD). Only high amplitude seizures cross the threshold of triggering this all-or-none event.
May 18, 2025 at 6:03 PM
In a mouse model, we observed that seizure is followed by a slow-traveling wave of maximal neural and hemodynamic activation followed by suppression, consistent with cortical spreading depolarization (CSD). Only high amplitude seizures cross the threshold of triggering this all-or-none event.
Why has this gone undetected for nearly 86 years? CSD wavefronts travel very slowly (millimeters per minute), such that when they are subjected to routine low frequency EEG filtering (our mainstay tool for brain monitoring during ECT), they’re rendered virtually invisible (right video panel).
May 18, 2025 at 5:45 PM
Why has this gone undetected for nearly 86 years? CSD wavefronts travel very slowly (millimeters per minute), such that when they are subjected to routine low frequency EEG filtering (our mainstay tool for brain monitoring during ECT), they’re rendered virtually invisible (right video panel).
In a mouse model, we observed that seizure is followed by a slow-traveling wave of maximal neural and hemodynamic activation followed by suppression, consistent with cortical spreading depolarization (CSD). Only high amplitude seizures cross the threshold of triggering this all-or-none event.
May 18, 2025 at 5:45 PM
In a mouse model, we observed that seizure is followed by a slow-traveling wave of maximal neural and hemodynamic activation followed by suppression, consistent with cortical spreading depolarization (CSD). Only high amplitude seizures cross the threshold of triggering this all-or-none event.