Yash Shukla
@yashshukla.bsky.social
Molecular biologist exploring protein translation & early development in C. elegans 🧬 | Ribosome profiling enthusiast | Investigating embryonic cell fate decisions @UT Austin | Cat dad 🐱
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How do tiny worm embryos decide which cells become muscle, nerve, or gut - all without reading any new DNA? 🤔
Our new Cell Reports paper explores this fascinating question using C. elegans embryos.
cell.com/cell-reports/fulltext/S2211-1247(25)00549-2
🧵 Thread below 👇
Our new Cell Reports paper explores this fascinating question using C. elegans embryos.
cell.com/cell-reports/fulltext/S2211-1247(25)00549-2
🧵 Thread below 👇
Landscape and regulation of mRNA translation in the early C. elegans embryo
Using ribosome profiling, Shukla et al. characterize dynamic translational regulation
of maternal mRNAs during the first four cell cycles of C. elegans development. Their
findings demonstrate how post...
cell.com
June 5, 2025 at 7:37 PM
How do tiny worm embryos decide which cells become muscle, nerve, or gut - all without reading any new DNA? 🤔
Our new Cell Reports paper explores this fascinating question using C. elegans embryos.
cell.com/cell-reports/fulltext/S2211-1247(25)00549-2
🧵 Thread below 👇
Our new Cell Reports paper explores this fascinating question using C. elegans embryos.
cell.com/cell-reports/fulltext/S2211-1247(25)00549-2
🧵 Thread below 👇
Reposted by Yash Shukla
Ever wondered how several individual RBPs cooperate to repress translation?
Lead by @marcopayr.bsky.social and in great collaboration with @hennig-lab.bsky.social, we simultaneously tracked the binding of several proteins to single mRNA molecules in real-time!
www.biorxiv.org/content/10.1...
Lead by @marcopayr.bsky.social and in great collaboration with @hennig-lab.bsky.social, we simultaneously tracked the binding of several proteins to single mRNA molecules in real-time!
www.biorxiv.org/content/10.1...
April 12, 2025 at 11:29 AM
Ever wondered how several individual RBPs cooperate to repress translation?
Lead by @marcopayr.bsky.social and in great collaboration with @hennig-lab.bsky.social, we simultaneously tracked the binding of several proteins to single mRNA molecules in real-time!
www.biorxiv.org/content/10.1...
Lead by @marcopayr.bsky.social and in great collaboration with @hennig-lab.bsky.social, we simultaneously tracked the binding of several proteins to single mRNA molecules in real-time!
www.biorxiv.org/content/10.1...
"New preprint! 🧬
biorxiv.org/content/10.1101/2024.12.13.628416v1
We explored protein translation regulation in early embryo development using C. elegans as our model. #DevBio #CElegans 1/3"
biorxiv.org/content/10.1101/2024.12.13.628416v1
We explored protein translation regulation in early embryo development using C. elegans as our model. #DevBio #CElegans 1/3"
Landscape and regulation of new protein translation in the early C. elegans embryo
www.biorxiv.org
December 19, 2024 at 12:27 AM
"New preprint! 🧬
biorxiv.org/content/10.1101/2024.12.13.628416v1
We explored protein translation regulation in early embryo development using C. elegans as our model. #DevBio #CElegans 1/3"
biorxiv.org/content/10.1101/2024.12.13.628416v1
We explored protein translation regulation in early embryo development using C. elegans as our model. #DevBio #CElegans 1/3"