Xavier Corominas-Teruel
@xavier-ct.bsky.social
Postdoctoral Neuroscientist
https://www.xcorominasteruel.com
Danish research center for magnetic resonance (DRCMR)
https://www.drcmr.dk/xavi
Combining imaging with brain stimulation TMS,EEG,MRI,tCS,TUS.
https://www.xcorominasteruel.com
Danish research center for magnetic resonance (DRCMR)
https://www.drcmr.dk/xavi
Combining imaging with brain stimulation TMS,EEG,MRI,tCS,TUS.
Reposted by Xavier Corominas-Teruel
🧠⚡ We present a biophysically grounded framework coupling realistic neuron morphologies to TMS.
Our model links direct axonal activation from L2/3 to L5 corticospinal neurons, revealing direction- & dose-dependent spatiotemporal patterns.
www.biorxiv.org/content/10.1...
Our model links direct axonal activation from L2/3 to L5 corticospinal neurons, revealing direction- & dose-dependent spatiotemporal patterns.
www.biorxiv.org/content/10.1...
A Coupling Model of Transcranial Magnetic Stimulation Induced Electric Fields to Neural State Variables
Transcranial magnetic stimulation (TMS) is a non-invasive brain stimulation technique used to modulate neural activity, with applications in clinical treatment, diagnostics, and neuroscientific resear...
www.biorxiv.org
August 15, 2025 at 8:51 PM
🧠⚡ We present a biophysically grounded framework coupling realistic neuron morphologies to TMS.
Our model links direct axonal activation from L2/3 to L5 corticospinal neurons, revealing direction- & dose-dependent spatiotemporal patterns.
www.biorxiv.org/content/10.1...
Our model links direct axonal activation from L2/3 to L5 corticospinal neurons, revealing direction- & dose-dependent spatiotemporal patterns.
www.biorxiv.org/content/10.1...
Reposted by Xavier Corominas-Teruel
PlanTUS-transducer position
Finding optimal transducer position for each participant is hard. You certainly can’t run all possible individualized simulations. Here’s a way to start better:
Find positions that respect
- transducer focus limits
- skull thickness
- transducer tilt, etc.
#PlanTUS
Finding optimal transducer position for each participant is hard. You certainly can’t run all possible individualized simulations. Here’s a way to start better:
Find positions that respect
- transducer focus limits
- skull thickness
- transducer tilt, etc.
#PlanTUS
🎯 Meet 𝐏𝐥𝐚𝐧𝐓𝐔𝐒: a fast, open-source tool to pick where to place a transducer for transcranial ultrasonic stimulation (TUS) on an individual head – before you run heavy simulations.
Paper: doi.org/10.1016/j.br...
Code & instructions: plan-tus.org
Paper: doi.org/10.1016/j.br...
Code & instructions: plan-tus.org
September 2, 2025 at 9:23 AM
PlanTUS-transducer position
Finding optimal transducer position for each participant is hard. You certainly can’t run all possible individualized simulations. Here’s a way to start better:
Find positions that respect
- transducer focus limits
- skull thickness
- transducer tilt, etc.
#PlanTUS
Finding optimal transducer position for each participant is hard. You certainly can’t run all possible individualized simulations. Here’s a way to start better:
Find positions that respect
- transducer focus limits
- skull thickness
- transducer tilt, etc.
#PlanTUS
Reposted by Xavier Corominas-Teruel
Optional: one score to guide choices – weight metrics into a composite map that ranks candidate placements.
September 1, 2025 at 6:16 PM
Optional: one score to guide choices – weight metrics into a composite map that ranks candidate placements.
Reposted by Xavier Corominas-Teruel
Causal necessity of human hippocampus for structure-based inference in learning https://www.biorxiv.org/content/10.1101/2025.08.19.664920v1
August 19, 2025 at 2:15 PM
Causal necessity of human hippocampus for structure-based inference in learning https://www.biorxiv.org/content/10.1101/2025.08.19.664920v1
Reposted by Xavier Corominas-Teruel
A Practical Preprocessing Pipeline for Concurrent TMS-iEEG: Critical Steps and Methodological Considerations https://www.biorxiv.org/content/10.1101/2025.08.13.670238v1
August 18, 2025 at 7:16 PM
A Practical Preprocessing Pipeline for Concurrent TMS-iEEG: Critical Steps and Methodological Considerations https://www.biorxiv.org/content/10.1101/2025.08.13.670238v1
Reposted by Xavier Corominas-Teruel
A Coupling Model of Transcranial Magnetic Stimulation Induced Electric Fields to Neural State Variables https://www.biorxiv.org/content/10.1101/2025.08.11.669601v1
August 15, 2025 at 8:15 PM
A Coupling Model of Transcranial Magnetic Stimulation Induced Electric Fields to Neural State Variables https://www.biorxiv.org/content/10.1101/2025.08.11.669601v1
Reposted by Xavier Corominas-Teruel
Just dropped in @natcomms.nature.com: we show that re-engaging a thalamic–ventral tegmental circuit with deep brain stimulation can reignite consciousness in patients with severe brain injury. Work led by Aaron Warren, with @andreashorn.org @foxmdphd.bsky.social @ others! tinyurl.com/4kz8j89b
A human brain network linked to restoration of consciousness after deep brain stimulation - Nature Communications
In people with severe brain injuries, stimulation restored consciousness by engaging a deep brain circuit for wakefulness—revealing a target that may also guide treatment in stroke and epilepsy.
www.nature.com
July 21, 2025 at 9:39 PM
Just dropped in @natcomms.nature.com: we show that re-engaging a thalamic–ventral tegmental circuit with deep brain stimulation can reignite consciousness in patients with severe brain injury. Work led by Aaron Warren, with @andreashorn.org @foxmdphd.bsky.social @ others! tinyurl.com/4kz8j89b
Reposted by Xavier Corominas-Teruel
🎉 40 Years of TMS: Registrations are now open!
We will be joined by experts in the field to reflect on four decades of progress and explore how TMS continues to push the boundaries of neuroscience, neuromodulation, and clinical practice.
➡️ Register Now: www.eventbrite.co.uk/e/tms-at-40-...
We will be joined by experts in the field to reflect on four decades of progress and explore how TMS continues to push the boundaries of neuroscience, neuromodulation, and clinical practice.
➡️ Register Now: www.eventbrite.co.uk/e/tms-at-40-...
TMS at 40
Celebrating 40 Years of Innovation and Advancing Frontiers in Transcranial Magnetic Stimulation
www.eventbrite.co.uk
July 29, 2025 at 11:15 AM
🎉 40 Years of TMS: Registrations are now open!
We will be joined by experts in the field to reflect on four decades of progress and explore how TMS continues to push the boundaries of neuroscience, neuromodulation, and clinical practice.
➡️ Register Now: www.eventbrite.co.uk/e/tms-at-40-...
We will be joined by experts in the field to reflect on four decades of progress and explore how TMS continues to push the boundaries of neuroscience, neuromodulation, and clinical practice.
➡️ Register Now: www.eventbrite.co.uk/e/tms-at-40-...
Reposted by Xavier Corominas-Teruel
/1 We took our sweet time (~3yrs) to put this into its final shape - but happy to say that the pre-print of an extensive review of brain rhythms in cognition - from a cognruro perspective - is now available. Please let us know what you think. #neuroskyence doi.org/10.48550/arX...
Brain rhythms in cognition -- controversies and future directions
Brain rhythms seem central to understanding the neurophysiological basis of human cognition. Yet, despite significant advances, key questions remain unresolved. In this comprehensive position paper, w...
doi.org
July 22, 2025 at 12:31 PM
/1 We took our sweet time (~3yrs) to put this into its final shape - but happy to say that the pre-print of an extensive review of brain rhythms in cognition - from a cognruro perspective - is now available. Please let us know what you think. #neuroskyence doi.org/10.48550/arX...
Reposted by Xavier Corominas-Teruel
Electrical #BrainStimulation can be used to modulate #brain activity but how does it affect the #CorticalLayers? This study shows that only the deeper layers show phase-dependent changes in local field potential components upon electrical stimulation @plosbiology.org 🧪 plos.io/406W3i5
July 9, 2025 at 8:32 AM
Electrical #BrainStimulation can be used to modulate #brain activity but how does it affect the #CorticalLayers? This study shows that only the deeper layers show phase-dependent changes in local field potential components upon electrical stimulation @plosbiology.org 🧪 plos.io/406W3i5
Reposted by Xavier Corominas-Teruel
📢 Just published in Frontiers in Neuroscience!
🧠⚡ Modulating excitation/inhibition balance through transcranial electrical stimulation: physiological mechanisms in animal models
🧠⚡ Modulating excitation/inhibition balance through transcranial electrical stimulation: physiological mechanisms in animal models
Frontiers | Modulating excitation/inhibition balance through transcranial electrical stimulation: physiological mechanisms in animal models
The balance between excitatory and inhibitory (E/I) activity is a fundamental property of neural circuits, ensuring precise information processing and preven...
doi.org
July 18, 2025 at 8:42 AM
📢 Just published in Frontiers in Neuroscience!
🧠⚡ Modulating excitation/inhibition balance through transcranial electrical stimulation: physiological mechanisms in animal models
🧠⚡ Modulating excitation/inhibition balance through transcranial electrical stimulation: physiological mechanisms in animal models
Reposted by Xavier Corominas-Teruel
Vridhi Rohira & colleagues propose combining magnetic resonance imaging (MRI)-based neuronavigation on a cerebellar spatially unbiased atlas template SUIT atlas to improve cerebellar TMS targeting.
www.brainstimjrnl.com/article/S193...
www.brainstimjrnl.com/article/S193...
Improving Cerebellar TMS Targeting: MRI-Neuronavigation and Landmark-Based Approaches Assessed by E-Field Modeling
Transcranial magnetic stimulation (TMS) is widely employed to modulate cerebellar
activity [1]. Although neuronavigation is widely used to target cortical regions,
cerebellar TMS is still predominantl...
www.brainstimjrnl.com
May 13, 2025 at 1:42 AM
Vridhi Rohira & colleagues propose combining magnetic resonance imaging (MRI)-based neuronavigation on a cerebellar spatially unbiased atlas template SUIT atlas to improve cerebellar TMS targeting.
www.brainstimjrnl.com/article/S193...
www.brainstimjrnl.com/article/S193...
Reposted by Xavier Corominas-Teruel
Maximilian Lueckel, Suhas Vijayakumar, Til Ole Bergmann: PlanTUS: A heuristic tool for prospective planning of transcranial ultrasound transducer placements https://arxiv.org/abs/2506.22563 https://arxiv.org/pdf/2506.22563 https://arxiv.org/html/2506.22563
July 1, 2025 at 6:47 AM
Maximilian Lueckel, Suhas Vijayakumar, Til Ole Bergmann: PlanTUS: A heuristic tool for prospective planning of transcranial ultrasound transducer placements https://arxiv.org/abs/2506.22563 https://arxiv.org/pdf/2506.22563 https://arxiv.org/html/2506.22563
Reposted by Xavier Corominas-Teruel
🚨 New paper alert from Weise et al.!
"A leadfield-free optimization framework for transcranially applied electric currents"
🔋 Optimize TES, TIS, ECT & TTFields without fixed leadfields
🧠 Electrode placement adapts to individual anatomy
💻 Now available in SimNIBS!
doi.org/10.1016/j.co...
"A leadfield-free optimization framework for transcranially applied electric currents"
🔋 Optimize TES, TIS, ECT & TTFields without fixed leadfields
🧠 Electrode placement adapts to individual anatomy
💻 Now available in SimNIBS!
doi.org/10.1016/j.co...
July 2, 2025 at 7:57 AM
🚨 New paper alert from Weise et al.!
"A leadfield-free optimization framework for transcranially applied electric currents"
🔋 Optimize TES, TIS, ECT & TTFields without fixed leadfields
🧠 Electrode placement adapts to individual anatomy
💻 Now available in SimNIBS!
doi.org/10.1016/j.co...
"A leadfield-free optimization framework for transcranially applied electric currents"
🔋 Optimize TES, TIS, ECT & TTFields without fixed leadfields
🧠 Electrode placement adapts to individual anatomy
💻 Now available in SimNIBS!
doi.org/10.1016/j.co...
Reposted by Xavier Corominas-Teruel
Low frequency oscillations – neural correlates of stability and flexibility in cognition
www.nature.com/articles/s41...
#neuroscience
www.nature.com/articles/s41...
#neuroscience
Low frequency oscillations – neural correlates of stability and flexibility in cognition - Nature Communications
How the brain balances the flexibility and stability needed to both encode and maintain information during cognition remains poorly understood. Using MEG data and in-silico simulations, the authors sh...
www.nature.com
June 28, 2025 at 4:54 PM
Low frequency oscillations – neural correlates of stability and flexibility in cognition
www.nature.com/articles/s41...
#neuroscience
www.nature.com/articles/s41...
#neuroscience
Reposted by Xavier Corominas-Teruel
Benchmarking methods for mapping functional connectivity in the brain | doi.org/10.1038/s415...
What is the best measure of functional connectivity (FC)?
led by @zhenqi.bsky.social in @natmethods.nature.com ⤵️
What is the best measure of functional connectivity (FC)?
led by @zhenqi.bsky.social in @natmethods.nature.com ⤵️
June 20, 2025 at 7:57 PM
Benchmarking methods for mapping functional connectivity in the brain | doi.org/10.1038/s415...
What is the best measure of functional connectivity (FC)?
led by @zhenqi.bsky.social in @natmethods.nature.com ⤵️
What is the best measure of functional connectivity (FC)?
led by @zhenqi.bsky.social in @natmethods.nature.com ⤵️
Reposted by Xavier Corominas-Teruel
Hold on to your transducers, TUS community! We've focused on managing what participants can hear during stimulation… but how about what they feel?! Our BrainStim paper maps tactile, thermal, & painful sensations during transcranial ultrasonic stimulation - and reveals how to minimize them. Thread👇
Parameter optimisation for mitigating somatosensory confounds during transcranial ultrasonic stimulation
Transcranial ultrasonic stimulation (TUS) redefines what is possible with non-invasive
neuromodulation by offering unparalleled spatial precision and flexible targeting
capabilities. However, peripher...
www.brainstimjrnl.com
June 19, 2025 at 8:18 PM
Hold on to your transducers, TUS community! We've focused on managing what participants can hear during stimulation… but how about what they feel?! Our BrainStim paper maps tactile, thermal, & painful sensations during transcranial ultrasonic stimulation - and reveals how to minimize them. Thread👇
Reposted by Xavier Corominas-Teruel
On the cover of the Journal of Neurosurgery, Jacob Young, MD & Manish Aghi, MD, PhD, review the role of focused ultrasound (FUS) in treating gliomas, highlighting how low-frequency FUS can disrupt the blood-brain barrier to enhance drug delivery: thejns.org/view/journal... @ucsfcancer.bsky.social
June 4, 2025 at 10:25 PM
On the cover of the Journal of Neurosurgery, Jacob Young, MD & Manish Aghi, MD, PhD, review the role of focused ultrasound (FUS) in treating gliomas, highlighting how low-frequency FUS can disrupt the blood-brain barrier to enhance drug delivery: thejns.org/view/journal... @ucsfcancer.bsky.social
Reposted by Xavier Corominas-Teruel
Autism is associated with inflexibility of brain dynamics. Watanabe and Yamasue show that TMS over the right superior parietal lobule while the brain is ‘stuck’ in a certain state reduces this rigidity and relieves various autistic traits.
@takamitsuw.bsky.social
www.nature.com/articles/s41...
@takamitsuw.bsky.social
www.nature.com/articles/s41...
Noninvasive reduction of neural rigidity alters autistic behaviors in humans - Nature Neuroscience
Autism is associated with inflexibility of brain dynamics. Watanabe and Yamasue show that TMS over the right superior parietal lobule while the brain is ‘stuck’ in a certain state reduces this rigidit...
www.nature.com
June 13, 2025 at 6:48 PM
Autism is associated with inflexibility of brain dynamics. Watanabe and Yamasue show that TMS over the right superior parietal lobule while the brain is ‘stuck’ in a certain state reduces this rigidity and relieves various autistic traits.
@takamitsuw.bsky.social
www.nature.com/articles/s41...
@takamitsuw.bsky.social
www.nature.com/articles/s41...
Reposted by Xavier Corominas-Teruel
Oscillatory impact of Transcranial Magnetic Stimulation at very weak-intensity on the primary motor cortex: A TMS-EEG study in the human brain https://www.biorxiv.org/content/10.1101/2025.02.04.636500v1
February 5, 2025 at 9:15 PM
Oscillatory impact of Transcranial Magnetic Stimulation at very weak-intensity on the primary motor cortex: A TMS-EEG study in the human brain https://www.biorxiv.org/content/10.1101/2025.02.04.636500v1
Reposted by Xavier Corominas-Teruel
EPICURUS: E-field-based spatial filtering procedure for an accurate estimation of local EEG activity evoked by Transcranial Magnetic Stimulation https://www.biorxiv.org/content/10.1101/2025.02.16.638512v1
February 19, 2025 at 10:15 AM
EPICURUS: E-field-based spatial filtering procedure for an accurate estimation of local EEG activity evoked by Transcranial Magnetic Stimulation https://www.biorxiv.org/content/10.1101/2025.02.16.638512v1
Reposted by Xavier Corominas-Teruel
Want to optimize cerebellar TMS?
Our latest paper by @VridhiRohira & @CorominasXavier shows how to improve targeting precision. Don’t miss it! 👇
Our latest paper by @VridhiRohira & @CorominasXavier shows how to improve targeting precision. Don’t miss it! 👇
Vridhi Rohira & colleagues propose combining magnetic resonance imaging (MRI)-based neuronavigation on a cerebellar spatially unbiased atlas template SUIT atlas to improve cerebellar TMS targeting.
www.brainstimjrnl.com/article/S193...
www.brainstimjrnl.com/article/S193...
Improving Cerebellar TMS Targeting: MRI-Neuronavigation and Landmark-Based Approaches Assessed by E-Field Modeling
Transcranial magnetic stimulation (TMS) is widely employed to modulate cerebellar
activity [1]. Although neuronavigation is widely used to target cortical regions,
cerebellar TMS is still predominantl...
www.brainstimjrnl.com
May 13, 2025 at 9:13 PM
Want to optimize cerebellar TMS?
Our latest paper by @VridhiRohira & @CorominasXavier shows how to improve targeting precision. Don’t miss it! 👇
Our latest paper by @VridhiRohira & @CorominasXavier shows how to improve targeting precision. Don’t miss it! 👇
Reposted by Xavier Corominas-Teruel
New landmark TMS trial dropped by Jonathan Downar's team, which will revolutionize care for depression even more than the SAINT trial did – extensive (10 hour!) sessions of TMS in a single day, enhanced by single dose of cycloserine. 90% response, 70% remission!
www.researchgate.net/publication/...
www.researchgate.net/publication/...
(PDF) Real-world effectiveness of a single-day regimen for transcranial magnetic stimulation using Optimized, Neuroplastogen-Enhanced techniques in Depression (ONE-D)
PDF | Background: Conventional transcranial magnetic stimulation (TMS) regimens are logistically burdensome, requiring days or weeks of clinic visits.... | Find, read and cite all the research you nee...
www.researchgate.net
December 27, 2024 at 2:35 PM
New landmark TMS trial dropped by Jonathan Downar's team, which will revolutionize care for depression even more than the SAINT trial did – extensive (10 hour!) sessions of TMS in a single day, enhanced by single dose of cycloserine. 90% response, 70% remission!
www.researchgate.net/publication/...
www.researchgate.net/publication/...