🔞 The Northstar✨ System
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supuhstar.com
🔞 The Northstar✨ System
@supuhstar.com
93 followers 180 following 380 posts
'91 • 🔞🏳️‍⚧️Ⓐ✊🏽∞&θ∆ • 우리는 한국어 배우기 중이어요 • Integrated DID system • >35 headmates • We are many & proud & healthy • Info: Supuhstar.com
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🔞 The Northstar✨ System @supuhstar.com · Feb 16
Here's what that SHOULD say
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wolf.mom
man is disgusting.
www.justice.gov/epstein/file...
man page entry for nvidia-smi
February 4, 2026 at 3:05 PM
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tangentfoxofficial.bsky.social
I just want to have a single day where Bluetooth doesn't hurt me.
January 30, 2026 at 3:38 AM
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weratedogs.com
This is Callie. She is trained to accurately detect bowel cancer in order to provide rapid diagnoses through non-invasive testing. Some might call it lab work, but Callie is actually a sprocker spaniel. 14/10 incredible job, Callie (IG: medicaldetectiondogs)
January 29, 2026 at 11:44 PM
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loulougirls.bsky.social
Fresh, chewy, golden‑crusted bagels… straight from your kitchen. 🥯✨
Yes, you. The bagel boss. The carb queen. The woman who can turn flour and water into a full‑blown bakery moment before 9 a.m.

www.loulougirls.com/homemade-bag...
January 26, 2026 at 10:41 PM
supuhstar.com
Nobody wants to hire anymore :(
January 27, 2026 at 1:16 AM
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gifs-bot.bsky.social
STARWARS/EMPEROR.GIF
January 25, 2026 at 1:20 PM
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vanillayote.bsky.social
Noise Complaint
You aren't really aware of WHEN you bark when you start turning into an animal, but you do. And allllll your neighbors can hear. 

A long since finished com from 11/17/24 for @somesortofyote.bsky.social
#art
An anthro coyote stands in an open door, sheepishly rubbing the back of her neck as a conversation happens with a landlord. The back and forth goes as follows; "Ms _____, As per your lease agreement there are no dogs allowed in your unit. We've received multiple calls from other tenants about-" "We dont have any dogs." "you dont have any dogs here?" "No. I mean. Technically, yes, but no. I can explain. M- The uh..." "the barking." "yeah ... the barking.... thatsme. sorryaboutthat" "you?" "Yea ive- well its. I can show you im- its involuntarysorryitwonthappenagain....." "OH! oh. ... that makes sense. regardless-.... still a noise complaint." "Yeah. wont happen again. I think"
January 24, 2026 at 1:52 AM
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tangentfoxofficial.bsky.social
The photo of Bush being informed a 2nd plane hit the WTC, but captioned "Sir, a second Sphere has hit the country."
January 21, 2026 at 9:29 PM
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nnaly.bsky.social
Day 139 of drawing Princess Luna

#mlp #mylittlepony #dailyluna
January 19, 2026 at 3:25 PM
supuhstar.com
Taylor Swift is old
January 15, 2026 at 2:55 AM
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nancycomics.bsky.social
THE FUN NEVER STOPS
WITH NANCY AND SLUGGO
NANCY: WHAT ARE YOU DOING ? SLUGGO WHENEVER I WRITE BANANA, I CAN'T STOP SLUGGO’S WRITING ON THE WALL. BUY A BANANANANANANANA TUESDAY
January 13, 2026 at 2:40 PM
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sailorrooscout.bsky.social
Oh to be a little Tardigrade walking across a microscope slide. 🫧🐻🧪
January 13, 2026 at 5:01 PM
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gingerbeardman.com
New blog post about a little tool I created to manage multiple localhost web servers from the macOS menu bar.

Controlling local web servers using xbar:
blog.gingerbeardman.com/2026/01/12/x...
Controlling local web servers using xbar  ⌘I  Get Info
Sometimes I want to run local web servers for projects I’m working on. Usually more than one at a time.
blog.gingerbeardman.com
January 12, 2026 at 9:48 PM
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bencollins.bsky.social
btw bluesky is having its biggest month in a while by the math
a chart showing a big, somewhat sustain spike in followers starting just before Christmas
January 13, 2026 at 4:08 PM
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michellestringer.bsky.social
Tweet by vanthiyathevan If a beautiful woman disagrees with me I will immediately change my views. I have no principles Response by kun @theekundavai well maybe you should have principles Response by vanthiyathevan you're right maybe I should
January 12, 2026 at 10:21 PM
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yuukidesu9.bsky.social
@jtfg.dev core
big and fluffy birb
curanull.bsky.social CuraNull @curanull.bsky.social · Jan 9
Just realized I get to post this one too!
January 9, 2026 at 6:27 PM
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sleepingirl.info
After dissatisfaction with the restaurants around here, I have finally sated my craving for Japanese curry.

Secret ingredients: applesauce and cocoa powder
January 7, 2026 at 8:33 PM
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lovebuns.bsky.social
This has been shortened a lot due to the BlueSky character limit 🥹

🐰 “Just a rabbit” brings out what’s good in me, and diverts my thoughts away from myself and the worries of the day.

~ Author unknown, and thanks to our Snowbelle for the cute picture. ❤🐇❤
Snowbelle, Himalayan Dwarf rabbit (white with ruby eyes, black nose, ears and paws) with an open mouth. The statement reads "So out of all the bunnies our there...you picked me?
January 8, 2026 at 2:55 PM
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nancycomics.bsky.social
Nancy By Ernie Bushmiller
January 02,1947
NANCY BY ERNIE BUSHMILLER P1- NANCY IS SLIDING BACKWARDS DOWN THE STAIR BANISTER, HER AUNT FRITZI IS VERY UPSET BY NANCY SLIDING DOWN THE BANISTER FRITZI: NANCY - - - GO RIGHT BACK UP AND COME DOWN LIKE A LADY P2-NANCY GOES UP THE STAIRS P3- NANCY SLIDES DOWN THE BANISTER, THIS TIME SHE IS SITTING SIDEWAYS , ONE HAND ON HER HIP, THE OTHER HAND BEHIND HER HEAD, SHE DESCENDS DOWN DOWN THE BANISTER WITH AN AIR OF COOLNESS.
January 2, 2026 at 9:25 PM
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queenrayna1337.bsky.social
January 1, 2026 at 1:01 PM
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sailorrooscout.bsky.social
GOOD NEWS! A group of patients with an otherwise incurable form of T‑cell leukemia have seen their cancer driven into REMISSION by an innovative immune therapy known as BE-CAR7. 82% of patients reached deep remission and 64% of patients have now been disease-free and OFF therapy for THREE years.
January 1, 2026 at 5:00 PM
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masonfromtwitter.bsky.social
I did not realize I had my "ask me about free STD partner treatment" pin from work on this jacket lol
If you live in Los Angeles and you have an STI you can get expedited partner therapy which means if you test positive for an STI they can get a dose of medicine for you too without you coming in
December 29, 2025 at 2:15 AM
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katriaraden.bsky.social
when in doubt, draw strawberries!!
acrylic markers on wood
photo of a wooden plaque with a drawing of stylised strawberries on a black background
December 28, 2025 at 11:03 PM
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sailorrooscout.bsky.social
In preclinical models, treatment repaired brain pathology, restored cognitive function, and normalized Alzheimer’s biomarkers (in HUMAN models as well).
• case.edu/news/new-stu...

The study has been published in Cell. YES, it is PEER-REVIEWED.
• www.cell.com/cell-reports...

🧪🧵⬇️
Highlights •Severity of Alzheimer's disease (AD) correlates with NAD+ homeostasis dysregulation •Preserving brain NAD+ homeostasis prevents AD in mice • Restoring brain NAD+ homeostasis reverses advanced AD in mice • Multiomics across human and mouse AD brain identifies nodes for human AD reversal Summary Alzheimer's has long been considered irreversible, but new research challenges that assumption. Scientists discovered that severe drops in the brain's energy supply help drive the disease-and restoring that balance can reverse damage, even in advanced cases. In mouse models, treatment repaired brain pathology, restored cognitive function, and normalized Alzheimer's biomarkers. The results offer fresh hope that recovery may be possible. Abstract Alzheimer's disease (AD) is traditionally considered irreversible. Here, however, we provide proof of principle for therapeutic reversibility of advanced AD. In advanced disease amyloid-driven 5xFAD mice, treatment with P7C3-A20, which restores nicotinamide adenine dinucleotide (NAD+) homeostasis, reverses tau phosphorylation, blood-brain barrier deterioration, oxidative stress, DNA damage, and neuroinflammation and enhances hippocampal neurogenesis and synaptic plasticity, resulting in full cognitive recovery and reduction of plasma levels of the clinical AD biomarker p-tau217. P7C3-A20 also reverses advanced disease in tau-driven PS19 mice and protects human brain microvascular endothelial cells from oxidative stress. In humans and mice, pathology severity correlates with disruption of brain NAD+ homeostasis, and the brains of nondemented people with Alzheimer's neuropathology exhibit gene expression patterns suggestive of preserved NAD+ homeostasis. Forty-six proteins aberrantly expressed in advanced 5xFAD mouse brain and normalized by P7C3-A20 show similar alterations in human AD brain, revealing targets with potential for optimizing translation to patient care. Graphical Abstract (CREDIT: Cell Reports Medicine)
December 28, 2025 at 5:03 PM