Struan Grant
@struangrant.bsky.social
Professor of Genetics and Pediatrics, UPenn/CHOP🧬. https://orcid.org/0000-0003-2025-5302. Views my own. 🏴🇺🇸
Pinned
Struan Grant
@struangrant.bsky.social
· Dec 15
Re-posting given recent adds
go.bsky.app/9asWtuD
go.bsky.app/9asWtuD
An outline of our recent bone 🦴 papers - with @j-a-mitchell.bsky.social and Babette Zemel. @chopresearch.bsky.social @penngenetics.bsky.social
www.chop.edu/preview-link...
www.chop.edu/preview-link...
Children’s Hospital of Philadelphia Researchers Identify Genetic Factors Influencing Bone Density in Pediatric Patients
Understanding the causal gene was related to the dynamic between osteoblasts, which form new bone tissue, and osteoclasts, which break down old bone tissue. When children are growing, osteoblasts are far more active to help achieve proper bone growth.
www.chop.edu
November 20, 2025 at 12:11 PM
An outline of our recent bone 🦴 papers - with @j-a-mitchell.bsky.social and Babette Zemel. @chopresearch.bsky.social @penngenetics.bsky.social
www.chop.edu/preview-link...
www.chop.edu/preview-link...
Reposted by Struan Grant
As an ASBMR Ambassador, I invite you to check out the ASBMR @asbmr.bsky.social 2026 Student Cohort Program www.asbmr.org/student-cohort. The application deadline has been extended to November 28, 2025.
ASBMR Student Cohort Program
A new cohort program designed for undergraduate, graduate, and medical professional students involved in the bone, mineral, and musculoskeletal field. This cohort program provides accepted applicants
www.asbmr.org
November 19, 2025 at 4:09 PM
As an ASBMR Ambassador, I invite you to check out the ASBMR @asbmr.bsky.social 2026 Student Cohort Program www.asbmr.org/student-cohort. The application deadline has been extended to November 28, 2025.
As an ASBMR Ambassador, I invite you to check out the ASBMR @asbmr.bsky.social 2026 Student Cohort Program www.asbmr.org/student-cohort. The application deadline has been extended to November 28, 2025.
ASBMR Student Cohort Program
A new cohort program designed for undergraduate, graduate, and medical professional students involved in the bone, mineral, and musculoskeletal field. This cohort program provides accepted applicants
www.asbmr.org
November 19, 2025 at 4:09 PM
As an ASBMR Ambassador, I invite you to check out the ASBMR @asbmr.bsky.social 2026 Student Cohort Program www.asbmr.org/student-cohort. The application deadline has been extended to November 28, 2025.
@shaonsengupta.bsky.social and I are still hiring! Please DM us if interested
www.nature.com/naturecareer...
www.nature.com/naturecareer...
Post Doctoral Research Fellow – Circadian Biology and Genomics - Philadelphia, Pennsylvania (US) job with Children's Hospital of Philadelphia | 12846607
A postdoctoral fellow is needed to join a strong team involved in spanning both dry and wet lab approaches.
www.nature.com
November 4, 2025 at 3:50 PM
@shaonsengupta.bsky.social and I are still hiring! Please DM us if interested
www.nature.com/naturecareer...
www.nature.com/naturecareer...
Penn Genetics @penngenetics.bsky.social and CHOP Genetics @chopresearch.bsky.social are at #ASHG25 Booth #1319 - come on by!
Re-posting given recent adds
go.bsky.app/9asWtuD
go.bsky.app/9asWtuD
October 17, 2025 at 1:25 PM
Penn Genetics @penngenetics.bsky.social and CHOP Genetics @chopresearch.bsky.social are at #ASHG25 Booth #1319 - come on by!
Reposted by Struan Grant
Re-posting given recent adds
go.bsky.app/9asWtuD
go.bsky.app/9asWtuD
December 15, 2024 at 3:01 PM
Re-posting given recent adds
go.bsky.app/9asWtuD
go.bsky.app/9asWtuD
I'll again be at the #ASHG25 Penn Genetics @penngenetics.bsky.social Booth #1319 1.30-2.30pm today - come on by!
Check out #ASHG25 Penn Genetics @penngenetics.bsky.social Booth #1319
Exhibit Level Halls A-B, Nonprofit and Advocacy Pavilion
Tuesday, October 15 - Thursday, October 17
Exhibit Level Halls A-B, Nonprofit and Advocacy Pavilion
Tuesday, October 15 - Thursday, October 17
October 17, 2025 at 12:37 PM
I'll again be at the #ASHG25 Penn Genetics @penngenetics.bsky.social Booth #1319 1.30-2.30pm today - come on by!
Come see Matt Pahl (@pahlmc.bsky.social) present at the #ASHG25 Session on Predicted Effector Genes.
Here are the details for the session:
Learn about the current predicted effector gene landscape
11:45AM-1:15PM ET
Room 259A
Here are the details for the session:
Learn about the current predicted effector gene landscape
11:45AM-1:15PM ET
Room 259A
Our #ASHG25 platform activities:
Vrathasha Vrathasha: 3D genomics & glaucoma. 206AB, W 10.45-11
Winter Bruner: MPRA & childhood obesity. 205ABC, T 11-11.15
Matt Pahl: Ancillary Session, Predicted Effector Genes. 259A, F 1.45-1.15
Struan Grant chairs Metabolic Matrix session. 253ABC, S 10-11
Vrathasha Vrathasha: 3D genomics & glaucoma. 206AB, W 10.45-11
Winter Bruner: MPRA & childhood obesity. 205ABC, T 11-11.15
Matt Pahl: Ancillary Session, Predicted Effector Genes. 259A, F 1.45-1.15
Struan Grant chairs Metabolic Matrix session. 253ABC, S 10-11
October 17, 2025 at 12:33 PM
Come see Matt Pahl (@pahlmc.bsky.social) present at the #ASHG25 Session on Predicted Effector Genes.
Here are the details for the session:
Learn about the current predicted effector gene landscape
11:45AM-1:15PM ET
Room 259A
Here are the details for the session:
Learn about the current predicted effector gene landscape
11:45AM-1:15PM ET
Room 259A
I'll again be at the #ASHG25 Penn Genetics
@penngenetics.bsky.social Booth #1319 3.30-4.30pm today - come on by!
@penngenetics.bsky.social Booth #1319 3.30-4.30pm today - come on by!
Check out #ASHG25 Penn Genetics @penngenetics.bsky.social Booth #1319
Exhibit Level Halls A-B, Nonprofit and Advocacy Pavilion
Tuesday, October 15 - Thursday, October 17
Exhibit Level Halls A-B, Nonprofit and Advocacy Pavilion
Tuesday, October 15 - Thursday, October 17
October 16, 2025 at 12:24 PM
I'll again be at the #ASHG25 Penn Genetics
@penngenetics.bsky.social Booth #1319 3.30-4.30pm today - come on by!
@penngenetics.bsky.social Booth #1319 3.30-4.30pm today - come on by!
Come see Winter Bruner, PhD today: "A comprehensive MPRA of both trans-ancestral genome-wide and suggestively-associated childhood obesity loci implicates a role for CBLN4 in microglia". Room 205ABC Thurs 11.00-11.15 Key contribution from Molly Ridler
Our #ASHG25 platform activities:
Vrathasha Vrathasha: 3D genomics & glaucoma. 206AB, W 10.45-11
Winter Bruner: MPRA & childhood obesity. 205ABC, T 11-11.15
Matt Pahl: Ancillary Session, Predicted Effector Genes. 259A, F 1.45-1.15
Struan Grant chairs Metabolic Matrix session. 253ABC, S 10-11
Vrathasha Vrathasha: 3D genomics & glaucoma. 206AB, W 10.45-11
Winter Bruner: MPRA & childhood obesity. 205ABC, T 11-11.15
Matt Pahl: Ancillary Session, Predicted Effector Genes. 259A, F 1.45-1.15
Struan Grant chairs Metabolic Matrix session. 253ABC, S 10-11
October 16, 2025 at 12:23 PM
Come see Winter Bruner, PhD today: "A comprehensive MPRA of both trans-ancestral genome-wide and suggestively-associated childhood obesity loci implicates a role for CBLN4 in microglia". Room 205ABC Thurs 11.00-11.15 Key contribution from Molly Ridler
I'll be at the #ASHG25 Penn Genetics @penngenetics.bsky.social Booth #1319 3.30-4.30pm today - come on by!
Check out #ASHG25 Penn Genetics @penngenetics.bsky.social Booth #1319
Exhibit Level Halls A-B, Nonprofit and Advocacy Pavilion
Tuesday, October 15 - Thursday, October 17
Exhibit Level Halls A-B, Nonprofit and Advocacy Pavilion
Tuesday, October 15 - Thursday, October 17
October 15, 2025 at 12:19 PM
I'll be at the #ASHG25 Penn Genetics @penngenetics.bsky.social Booth #1319 3.30-4.30pm today - come on by!
Reposted by Struan Grant
Check out #ASHG25 Penn Genetics @penngenetics.bsky.social Booth #1319
Exhibit Level Halls A-B, Nonprofit and Advocacy Pavilion
Tuesday, October 15 - Thursday, October 17
Exhibit Level Halls A-B, Nonprofit and Advocacy Pavilion
Tuesday, October 15 - Thursday, October 17
October 14, 2025 at 3:09 PM
Check out #ASHG25 Penn Genetics @penngenetics.bsky.social Booth #1319
Exhibit Level Halls A-B, Nonprofit and Advocacy Pavilion
Tuesday, October 15 - Thursday, October 17
Exhibit Level Halls A-B, Nonprofit and Advocacy Pavilion
Tuesday, October 15 - Thursday, October 17
Great collaboration with the Joan O'Brien team - come see Vrathasha Vrathasha today: "3D genomic approaches mapping accessible chromatin and architecture implicate causal risk variants in primary open-angle glaucoma pathogenesis". Key contribution from @pahlmc.bsky.social. 10.45-11.00am Room 206AB
Our #ASHG25 platform activities:
Vrathasha Vrathasha: 3D genomics & glaucoma. 206AB, W 10.45-11
Winter Bruner: MPRA & childhood obesity. 205ABC, T 11-11.15
Matt Pahl: Ancillary Session, Predicted Effector Genes. 259A, F 1.45-1.15
Struan Grant chairs Metabolic Matrix session. 253ABC, S 10-11
Vrathasha Vrathasha: 3D genomics & glaucoma. 206AB, W 10.45-11
Winter Bruner: MPRA & childhood obesity. 205ABC, T 11-11.15
Matt Pahl: Ancillary Session, Predicted Effector Genes. 259A, F 1.45-1.15
Struan Grant chairs Metabolic Matrix session. 253ABC, S 10-11
October 15, 2025 at 12:10 PM
Great collaboration with the Joan O'Brien team - come see Vrathasha Vrathasha today: "3D genomic approaches mapping accessible chromatin and architecture implicate causal risk variants in primary open-angle glaucoma pathogenesis". Key contribution from @pahlmc.bsky.social. 10.45-11.00am Room 206AB
Reposted by Struan Grant
Can’t believe #ASHG25 is finally here! Excited to share what I’ve been working on as lead analyst for the Global Lipids Genetics Consortium 🧬👩💻
Join me at the Plenary Session on Friday, Oct 17 (5–6:30 PM) — I’ll be presenting some unpublished results from our genome-wide interaction study 👀
Join me at the Plenary Session on Friday, Oct 17 (5–6:30 PM) — I’ll be presenting some unpublished results from our genome-wide interaction study 👀
October 14, 2025 at 7:15 PM
Can’t believe #ASHG25 is finally here! Excited to share what I’ve been working on as lead analyst for the Global Lipids Genetics Consortium 🧬👩💻
Join me at the Plenary Session on Friday, Oct 17 (5–6:30 PM) — I’ll be presenting some unpublished results from our genome-wide interaction study 👀
Join me at the Plenary Session on Friday, Oct 17 (5–6:30 PM) — I’ll be presenting some unpublished results from our genome-wide interaction study 👀
Reposted by Struan Grant
Our team is excited to meet folks at #ASHG25 #kidneyomics
We’re excited to share that the Sampson Lab and Dongwon Lee Labs will be at ASHG 2025! 🎉 This year, our team is presenting 7 posters, and we can’t wait to connect, learn, and exchange ideas. If you’re attending, come check out our posters! #ASHG2025
@kidneyomicsamps.bsky.social
@kidneyomicsamps.bsky.social
October 14, 2025 at 6:07 PM
Our team is excited to meet folks at #ASHG25 #kidneyomics
Reposted by Struan Grant
I'll be at #ASHG25 this week! Check out my poster Wed 2:30-4:30, at 5071W.
"Bridging the GWAS-eQTL colocalization gap with insights from caQTL analyses" with @struangrant.bsky.social and Laura Almasy
"Bridging the GWAS-eQTL colocalization gap with insights from caQTL analyses" with @struangrant.bsky.social and Laura Almasy
October 14, 2025 at 7:13 PM
I'll be at #ASHG25 this week! Check out my poster Wed 2:30-4:30, at 5071W.
"Bridging the GWAS-eQTL colocalization gap with insights from caQTL analyses" with @struangrant.bsky.social and Laura Almasy
"Bridging the GWAS-eQTL colocalization gap with insights from caQTL analyses" with @struangrant.bsky.social and Laura Almasy
Our #ASHG25 poster activities each day:
1097W Khanh Trang: Bone*
5071W Max Dudek: caQTLs
8042W Amber Zimmerman: Sleep
4083W Anthony Gacita: Pathogenic noncoding variants
9252T Mary Ann Weidekamp: Neuro & metab LDSC
5047T Ekta Singh: Ciliopathies
9206F Matthew Pahl: Glaucoma V2G*
*Reviewers’ Choice
1097W Khanh Trang: Bone*
5071W Max Dudek: caQTLs
8042W Amber Zimmerman: Sleep
4083W Anthony Gacita: Pathogenic noncoding variants
9252T Mary Ann Weidekamp: Neuro & metab LDSC
5047T Ekta Singh: Ciliopathies
9206F Matthew Pahl: Glaucoma V2G*
*Reviewers’ Choice
October 14, 2025 at 7:17 PM
Our #ASHG25 poster activities each day:
1097W Khanh Trang: Bone*
5071W Max Dudek: caQTLs
8042W Amber Zimmerman: Sleep
4083W Anthony Gacita: Pathogenic noncoding variants
9252T Mary Ann Weidekamp: Neuro & metab LDSC
5047T Ekta Singh: Ciliopathies
9206F Matthew Pahl: Glaucoma V2G*
*Reviewers’ Choice
1097W Khanh Trang: Bone*
5071W Max Dudek: caQTLs
8042W Amber Zimmerman: Sleep
4083W Anthony Gacita: Pathogenic noncoding variants
9252T Mary Ann Weidekamp: Neuro & metab LDSC
5047T Ekta Singh: Ciliopathies
9206F Matthew Pahl: Glaucoma V2G*
*Reviewers’ Choice
Reposted by Struan Grant
Finalizing my slides for #ASHG25 while on my flight to Boston in true PI fashion. Come check out the finished product tomorrow morning at 10:45am in the excitingly named "Seq-ing Function with Single Cells and CRISPR Perturbations" session! 🙂
October 14, 2025 at 4:43 PM
Finalizing my slides for #ASHG25 while on my flight to Boston in true PI fashion. Come check out the finished product tomorrow morning at 10:45am in the excitingly named "Seq-ing Function with Single Cells and CRISPR Perturbations" session! 🙂
Check out #ASHG25 Penn Genetics @penngenetics.bsky.social Booth #1319
Exhibit Level Halls A-B, Nonprofit and Advocacy Pavilion
Tuesday, October 15 - Thursday, October 17
Exhibit Level Halls A-B, Nonprofit and Advocacy Pavilion
Tuesday, October 15 - Thursday, October 17
October 14, 2025 at 3:09 PM
Check out #ASHG25 Penn Genetics @penngenetics.bsky.social Booth #1319
Exhibit Level Halls A-B, Nonprofit and Advocacy Pavilion
Tuesday, October 15 - Thursday, October 17
Exhibit Level Halls A-B, Nonprofit and Advocacy Pavilion
Tuesday, October 15 - Thursday, October 17
Just out: Led by @j-a-mitchell.bsky.social and Babette Zemel "gSOS Polygenic Score is Associated with Bone Density and Fracture Risk in Childhood" @asbmr.bsky.social. Funded by our #NICHD award R01 HD100406. @chopresearch.bsky.social @penngenetics.bsky.social
academic.oup.com/jbmr/article...
academic.oup.com/jbmr/article...
The gSOS Polygenic Score is Associated with Bone Density and Fracture Risk in Childhood
Abstract. The polygenic risk score genetic quantitative ultrasound speed of sound (gSOS) was developed using machine learning algorithms in adults of Europ
academic.oup.com
October 14, 2025 at 1:42 PM
Just out: Led by @j-a-mitchell.bsky.social and Babette Zemel "gSOS Polygenic Score is Associated with Bone Density and Fracture Risk in Childhood" @asbmr.bsky.social. Funded by our #NICHD award R01 HD100406. @chopresearch.bsky.social @penngenetics.bsky.social
academic.oup.com/jbmr/article...
academic.oup.com/jbmr/article...
Reposted by Struan Grant
Open to connecting with potential candidates at #ASHG25 !
My lab is seeking to co-hire a postdoctoral fellow with the
@shaonsengupta.bsky.social team. See details below!
I'll be #ASHG2025, so open to discuss further there if interest.
careers.chop.edu/us/en/job/10...
@shaonsengupta.bsky.social team. See details below!
I'll be #ASHG2025, so open to discuss further there if interest.
careers.chop.edu/us/en/job/10...
October 14, 2025 at 12:45 PM
Open to connecting with potential candidates at #ASHG25 !
My lab is seeking to co-hire a postdoctoral fellow with the
@shaonsengupta.bsky.social team. See details below!
I'll be #ASHG2025, so open to discuss further there if interest.
careers.chop.edu/us/en/job/10...
@shaonsengupta.bsky.social team. See details below!
I'll be #ASHG2025, so open to discuss further there if interest.
careers.chop.edu/us/en/job/10...
Post Doctoral Research Fellow – Circadian Biology and Genomics in Philadelphia, Pennsylvania, United States of America | Fellows, Students & Interns at Children’s Hospital of Philadelphia
Apply for Post Doctoral Research Fellow – Circadian Biology and Genomics job with Children’s Hospital of Philadelphia in Philadelphia, Pennsylvania, United States of America. Fellows, Students & Inter...
careers.chop.edu
October 14, 2025 at 12:25 PM
Open to connecting with potential candidates at #ASHG25 !
Our #ASHG25 platform activities:
Vrathasha Vrathasha: 3D genomics & glaucoma. 206AB, W 10.45-11
Winter Bruner: MPRA & childhood obesity. 205ABC, T 11-11.15
Matt Pahl: Ancillary Session, Predicted Effector Genes. 259A, F 1.45-1.15
Struan Grant chairs Metabolic Matrix session. 253ABC, S 10-11
Vrathasha Vrathasha: 3D genomics & glaucoma. 206AB, W 10.45-11
Winter Bruner: MPRA & childhood obesity. 205ABC, T 11-11.15
Matt Pahl: Ancillary Session, Predicted Effector Genes. 259A, F 1.45-1.15
Struan Grant chairs Metabolic Matrix session. 253ABC, S 10-11
October 14, 2025 at 11:20 AM
Our #ASHG25 platform activities:
Vrathasha Vrathasha: 3D genomics & glaucoma. 206AB, W 10.45-11
Winter Bruner: MPRA & childhood obesity. 205ABC, T 11-11.15
Matt Pahl: Ancillary Session, Predicted Effector Genes. 259A, F 1.45-1.15
Struan Grant chairs Metabolic Matrix session. 253ABC, S 10-11
Vrathasha Vrathasha: 3D genomics & glaucoma. 206AB, W 10.45-11
Winter Bruner: MPRA & childhood obesity. 205ABC, T 11-11.15
Matt Pahl: Ancillary Session, Predicted Effector Genes. 259A, F 1.45-1.15
Struan Grant chairs Metabolic Matrix session. 253ABC, S 10-11
A fun day hanging with Tom Romer @chopshopstore.bsky.social, designer extraordinaire!
Was in Washington DC on Monday with @struangrant.bsky.social and @planetarysociety.bsky.social meet with our Pennsylvania Representatives and support @nasascience.bsky.social
October 11, 2025 at 9:42 PM
A fun day hanging with Tom Romer @chopshopstore.bsky.social, designer extraordinaire!