Sanjay Mukhopadhyay
@smlungpathguy.bsky.social
I'm a pathologist (thoracic pathology), skeptic and opponent of groupthink
Fungal hyphae are more tricky to diagnose by pathology alone than yeasts
See detailed discussion here:
journals.sagepub.com/doi/10.1177/...
#pathsky #fungal #pathology
See detailed discussion here:
journals.sagepub.com/doi/10.1177/...
#pathsky #fungal #pathology
November 22, 2025 at 2:30 PM
Fungal hyphae are more tricky to diagnose by pathology alone than yeasts
See detailed discussion here:
journals.sagepub.com/doi/10.1177/...
#pathsky #fungal #pathology
See detailed discussion here:
journals.sagepub.com/doi/10.1177/...
#pathsky #fungal #pathology
Hot off the press! New paper by Paula Toro et al showing the accuracy of fungal infection by pathology. 26-year experience!
journals.sagepub.com/doi/10.1177/...
journals.sagepub.com/doi/10.1177/...
November 22, 2025 at 2:21 PM
Hot off the press! New paper by Paula Toro et al showing the accuracy of fungal infection by pathology. 26-year experience!
journals.sagepub.com/doi/10.1177/...
journals.sagepub.com/doi/10.1177/...
Cryptococcus can be diagnosed with high accuracy in surgical pathology or cytology specimens
Case 5, Table 1
#pathology #pathsky
Read the paper!
journals.sagepub.com/doi/10.1177/...
Case 5, Table 1
#pathology #pathsky
Read the paper!
journals.sagepub.com/doi/10.1177/...
November 21, 2025 at 11:34 AM
Cryptococcus can be diagnosed with high accuracy in surgical pathology or cytology specimens
Case 5, Table 1
#pathology #pathsky
Read the paper!
journals.sagepub.com/doi/10.1177/...
Case 5, Table 1
#pathology #pathsky
Read the paper!
journals.sagepub.com/doi/10.1177/...
#pathsky this is my favorite pathology conference of the year with the best, most practical speakers. I guarantee you will learn new things you can use in your practice!
Register here!
www.ccfcme.org/pathology26
Register here!
www.ccfcme.org/pathology26
October 28, 2025 at 8:43 AM
#pathsky this is my favorite pathology conference of the year with the best, most practical speakers. I guarantee you will learn new things you can use in your practice!
Register here!
www.ccfcme.org/pathology26
Register here!
www.ccfcme.org/pathology26
Learn GU, breast, GYN, GI and thoracic pathology from the best teachers. Sign up now!
www.clevelandclinicmeded.com/live/courses...
www.clevelandclinicmeded.com/live/courses...
September 24, 2025 at 1:23 AM
Learn GU, breast, GYN, GI and thoracic pathology from the best teachers. Sign up now!
www.clevelandclinicmeded.com/live/courses...
www.clevelandclinicmeded.com/live/courses...
Lymphangioleiomyomatosis:
1. Yet another misnomer in #pulmpath
2. PEComatous proliferations in walls of lung cysts
3. ALWAYS consider in women with bilateral lung cysts, recurrent pneumothoraces, tuberous sclerosis or renal angiomyolipoma
4. VERY IMPORTANT for boards
#pathsky
1. Yet another misnomer in #pulmpath
2. PEComatous proliferations in walls of lung cysts
3. ALWAYS consider in women with bilateral lung cysts, recurrent pneumothoraces, tuberous sclerosis or renal angiomyolipoma
4. VERY IMPORTANT for boards
#pathsky
September 1, 2025 at 4:41 AM
Learn to differentiate fibroblast foci (this image) from fibroblast plugs (Masson bodies), or you will never learn to diagnose UIP and forever be "correlating" with CT findings. Don't misdiagnose UIP as organizing pneumonia!
#pathology #pulmpath #uip #pathsky
#pathology #pulmpath #uip #pathsky
August 29, 2025 at 11:57 PM
Learn to differentiate fibroblast foci (this image) from fibroblast plugs (Masson bodies), or you will never learn to diagnose UIP and forever be "correlating" with CT findings. Don't misdiagnose UIP as organizing pneumonia!
#pathology #pulmpath #uip #pathsky
#pathology #pulmpath #uip #pathsky
August 19, 2025 at 12:52 AM
July 31, 2025 at 12:37 PM
PGY1s, you will learn about special stains that help to pick out microorganisms (AFB, GMS, PAS). But remember that many bugs are also visible on routine stains such as H&E and pap (used in cytology, shown here). Arrow: Histoplasma yeasts (dots) within a large histiocyte #pathsky
July 6, 2025 at 3:11 PM
PGY1s, you will learn about special stains that help to pick out microorganisms (AFB, GMS, PAS). But remember that many bugs are also visible on routine stains such as H&E and pap (used in cytology, shown here). Arrow: Histoplasma yeasts (dots) within a large histiocyte #pathsky
Disseminated histoplasmosis, cytology, BAL specimen, pap stain #pathology #pulmpath #pathsky
In lung specimens, this morphology is a surrogate for disseminated disease
pubmed.ncbi.nlm.nih.gov/24054723/
In lung specimens, this morphology is a surrogate for disseminated disease
pubmed.ncbi.nlm.nih.gov/24054723/
July 6, 2025 at 2:56 PM
Disseminated histoplasmosis, cytology, BAL specimen, pap stain #pathology #pulmpath #pathsky
In lung specimens, this morphology is a surrogate for disseminated disease
pubmed.ncbi.nlm.nih.gov/24054723/
In lung specimens, this morphology is a surrogate for disseminated disease
pubmed.ncbi.nlm.nih.gov/24054723/
July 6, 2025 at 2:08 PM
July 6, 2025 at 2:06 PM
PGY1s: the "cribriform" growth pattern occurs in many cancers including adenoid cystic carcinoma and prostate cancer. It results when many small glands are packed together back to back into a sieve-like collection of lumens. From Latin (cribrum = sieve) #pathology #pulmpath #pathsky
June 17, 2025 at 11:13 PM
PGY1s: the "cribriform" growth pattern occurs in many cancers including adenoid cystic carcinoma and prostate cancer. It results when many small glands are packed together back to back into a sieve-like collection of lumens. From Latin (cribrum = sieve) #pathology #pulmpath #pathsky
Mesothelial cells in transbronchial biopsy
Difficult question but kudos to @EvidenceOpen for citing Bejarano et al
#pathology #pulmpath #pathsky
Difficult question but kudos to @EvidenceOpen for citing Bejarano et al
#pathology #pulmpath #pathsky
June 4, 2025 at 2:36 AM
Mesothelial cells in transbronchial biopsy
Difficult question but kudos to @EvidenceOpen for citing Bejarano et al
#pathology #pulmpath #pathsky
Difficult question but kudos to @EvidenceOpen for citing Bejarano et al
#pathology #pulmpath #pathsky
May 24, 2025 at 1:31 AM
May 4, 2025 at 12:10 PM
May 4, 2025 at 12:01 PM
I ...
✳️ lay eggs on perianal skin that stick to "Scotch tape"
✳️ lay eggs that are slightly flat on one side and survive for 2-3 weeks on bedsheets
✳️ cause the most common worm infection in the USA
✳️ cause intense perianal itching at night
...who am I?
✳️ lay eggs on perianal skin that stick to "Scotch tape"
✳️ lay eggs that are slightly flat on one side and survive for 2-3 weeks on bedsheets
✳️ cause the most common worm infection in the USA
✳️ cause intense perianal itching at night
...who am I?
May 2, 2025 at 10:42 AM
I ...
✳️ lay eggs on perianal skin that stick to "Scotch tape"
✳️ lay eggs that are slightly flat on one side and survive for 2-3 weeks on bedsheets
✳️ cause the most common worm infection in the USA
✳️ cause intense perianal itching at night
...who am I?
✳️ lay eggs on perianal skin that stick to "Scotch tape"
✳️ lay eggs that are slightly flat on one side and survive for 2-3 weeks on bedsheets
✳️ cause the most common worm infection in the USA
✳️ cause intense perianal itching at night
...who am I?
Grok says this is a bronchiole 🙄
May 2, 2025 at 12:47 AM
Grok says this is a bronchiole 🙄
How pathologists tell benign from malignant has always fascinated me. Is the lesion in these images (lets's assume it's a biopsy of a lung mass) benign or malignant? Please explain your thought process so others can learn.
April 23, 2025 at 3:13 AM
How pathologists tell benign from malignant has always fascinated me. Is the lesion in these images (lets's assume it's a biopsy of a lung mass) benign or malignant? Please explain your thought process so others can learn.
Great day for a walk!
April 21, 2025 at 2:30 AM
Great day for a walk!
Granulomas of sarcoidosis vs "granulomas" of hypersensitivity pneumonitis
#pathsky #pathology #pulmpath
#pathsky #pathology #pulmpath
April 19, 2025 at 1:49 AM
Granulomas of sarcoidosis vs "granulomas" of hypersensitivity pneumonitis
#pathsky #pathology #pulmpath
#pathsky #pathology #pulmpath