@slonchak.bsky.social
Celebrating an epic year with an even more epic team. Grateful to my team for the science through the year and the laughs at the lab Christmas party and to Ukrainian Club Brisbane for fantastic food and flavoured vodkas 🎄🧬🥂
November 29, 2025 at 8:11 PM
Celebrating an epic year with an even more epic team. Grateful to my team for the science through the year and the laughs at the lab Christmas party and to Ukrainian Club Brisbane for fantastic food and flavoured vodkas 🎄🧬🥂
Congratulations to @rhyshparry.bsky.social on award of DECRA by ARC
November 25, 2025 at 7:05 PM
Congratulations to @rhyshparry.bsky.social on award of DECRA by ARC
Had fantastic time enjoying two days of #organoid talks and engagement with research and industry leaders in the field. Also congratulations to @leitnerm.bsky.social for successful presentation of his first results in our new lab at @qimrb.bsky.social
November 21, 2025 at 6:09 AM
Had fantastic time enjoying two days of #organoid talks and engagement with research and industry leaders in the field. Also congratulations to @leitnerm.bsky.social for successful presentation of his first results in our new lab at @qimrb.bsky.social
Was my pleasure to present our brain organoid model of flavivirus infection at Organoid Nexus symposium in sunny Melbourne.
November 21, 2025 at 5:19 AM
Was my pleasure to present our brain organoid model of flavivirus infection at Organoid Nexus symposium in sunny Melbourne.
Reposted
New preprint from the Khromykh/ @slonchak.bsky.social /Short lab 👇
In primary human nasal epithelia, #Omicron BA.5 & XBB show enhanced ciliated-cell tropism and a striking cilia-gene shutdown plus apoptosis/inflammation, unlike ancestral virus or BA.1.
Preprint:
www.biorxiv.org/content/10.1...
In primary human nasal epithelia, #Omicron BA.5 & XBB show enhanced ciliated-cell tropism and a striking cilia-gene shutdown plus apoptosis/inflammation, unlike ancestral virus or BA.1.
Preprint:
www.biorxiv.org/content/10.1...
November 21, 2025 at 3:51 AM
New preprint from the Khromykh/ @slonchak.bsky.social /Short lab 👇
In primary human nasal epithelia, #Omicron BA.5 & XBB show enhanced ciliated-cell tropism and a striking cilia-gene shutdown plus apoptosis/inflammation, unlike ancestral virus or BA.1.
Preprint:
www.biorxiv.org/content/10.1...
In primary human nasal epithelia, #Omicron BA.5 & XBB show enhanced ciliated-cell tropism and a striking cilia-gene shutdown plus apoptosis/inflammation, unlike ancestral virus or BA.1.
Preprint:
www.biorxiv.org/content/10.1...
Excited to learn about the most recent advances in organoid technologies at #MonashOrganoidSymposium
November 19, 2025 at 10:08 PM
Excited to learn about the most recent advances in organoid technologies at #MonashOrganoidSymposium
Amazing night celebrating 80 years of @qimrb.bsky.social at gala dinner with a fantastic cohort of distinguished guests!
November 1, 2025 at 10:53 AM
Amazing night celebrating 80 years of @qimrb.bsky.social at gala dinner with a fantastic cohort of distinguished guests!
Reposted
The IFIT2–IFIT3 antiviral complex targets short 5’ untranslated regions on viral mRNAs for translation inhibition
By Dustin Glasner, Matthew Daugherty & colleagues.
#microsky
www.nature.com/articles/s41...
By Dustin Glasner, Matthew Daugherty & colleagues.
#microsky
www.nature.com/articles/s41...
The IFIT2–IFIT3 antiviral complex targets short 5’ untranslated regions on viral mRNAs for translation inhibition - Nature Microbiology
Viruses generally have compact genomes, resulting in many viral mRNAs with short 5’ untranslated regions. An antiviral complex exploits this feature of viral mRNAs to selectively inhibit viral protein...
www.nature.com
October 15, 2025 at 4:59 PM
The IFIT2–IFIT3 antiviral complex targets short 5’ untranslated regions on viral mRNAs for translation inhibition
By Dustin Glasner, Matthew Daugherty & colleagues.
#microsky
www.nature.com/articles/s41...
By Dustin Glasner, Matthew Daugherty & colleagues.
#microsky
www.nature.com/articles/s41...
Probes for multicoloured RNA FISH look so vibrant! Can’t wait to see the beautiful slide scans! Made by @carlaprvieira.bsky.social at Systems Virology Lab.
October 16, 2025 at 10:37 AM
Probes for multicoloured RNA FISH look so vibrant! Can’t wait to see the beautiful slide scans! Made by @carlaprvieira.bsky.social at Systems Virology Lab.
Team work makes dream work. Especially when setting up a new lab @qimrb.bsky.social
July 1, 2025 at 8:24 AM
Team work makes dream work. Especially when setting up a new lab @qimrb.bsky.social
Systems virology team has arrived to our new amazing home at @qimrb.bsky.social It was an exciting first day unpacking and unboxing and thank you to my fantastic team for their effort in getting setup!
July 1, 2025 at 8:03 AM
Systems virology team has arrived to our new amazing home at @qimrb.bsky.social It was an exciting first day unpacking and unboxing and thank you to my fantastic team for their effort in getting setup!
Today was my farewell party at Khromykh’s lab, which felt like an end of an era. I definitely had amazing time working alongside all the amazing people there and developing my leadership with Alex’s help. Thank you @rhyshparry.bsky.social for organising this.
June 13, 2025 at 9:06 AM
Today was my farewell party at Khromykh’s lab, which felt like an end of an era. I definitely had amazing time working alongside all the amazing people there and developing my leadership with Alex’s help. Thank you @rhyshparry.bsky.social for organising this.
Reposted
@slonchak.bsky.social presenting his work on viral pathogenesis in human brain organoid models using single cell sequencing. Hisnlast presentation at #uqscmb before he heads to @qimrb.bsky.social to head his own lab
May 14, 2025 at 2:11 AM
@slonchak.bsky.social presenting his work on viral pathogenesis in human brain organoid models using single cell sequencing. Hisnlast presentation at #uqscmb before he heads to @qimrb.bsky.social to head his own lab
Today I’m learning about most recent innovations in single cell and spatial technologies from @10xgenomics.bsky.social experts and users at Brisbane’s Single Cell and Spatial Symposium. Very exciting how quickly this field is developing blinking new opportunities to researchers and clinicians.
April 4, 2025 at 2:42 AM
Today I’m learning about most recent innovations in single cell and spatial technologies from @10xgenomics.bsky.social experts and users at Brisbane’s Single Cell and Spatial Symposium. Very exciting how quickly this field is developing blinking new opportunities to researchers and clinicians.
It’s always a plus when the conference is being held in a place of stunning natural beauty. On the last day of #lorneiandi a got to get my drone up to capture the beauty of the location from the birds eye view. What an amazing place! @theviin.bsky.social
February 22, 2025 at 6:50 AM
It’s always a plus when the conference is being held in a place of stunning natural beauty. On the last day of #lorneiandi a got to get my drone up to capture the beauty of the location from the birds eye view. What an amazing place! @theviin.bsky.social
Reposted
Feeling very grateful to receive an early career development and ECR oral presentation award at Lorne I&I @theviin.bsky.social An amazing few days in Lorne learning about all types of pathogens and host responses. Great science at a stunning location!
February 21, 2025 at 3:10 AM
Feeling very grateful to receive an early career development and ECR oral presentation award at Lorne I&I @theviin.bsky.social An amazing few days in Lorne learning about all types of pathogens and host responses. Great science at a stunning location!
Host tRNAs as novel player in antiviral response. Presented by @lachdehayr.bsky.social at Lorne I&I conference @theviin.bsky.social
February 20, 2025 at 6:26 AM
Host tRNAs as novel player in antiviral response. Presented by @lachdehayr.bsky.social at Lorne I&I conference @theviin.bsky.social
Reposted
@slonchak.bsky.social's excellent presentation on his work studying WNV neuropathology using state of the art human brain organoids and single cell sequencing #UQSCMB
Exciting work by Dr Andrii Slonchak on using virus-inclusive scRNA-Seq to reveal the mechanism of flavivirus neuropathogenesis #lorneiandi
February 20, 2025 at 1:17 AM
@slonchak.bsky.social's excellent presentation on his work studying WNV neuropathology using state of the art human brain organoids and single cell sequencing #UQSCMB
What was happening in my hotel room while I was attending the sessions at Lorne I&I conference @theviin.bsky.social Cheeky #cockatoos !
February 19, 2025 at 10:28 AM
What was happening in my hotel room while I was attending the sessions at Lorne I&I conference @theviin.bsky.social Cheeky #cockatoos !
Reposted
Our paper and the first from our PhD student talking about the current state of flavivirus vaccines. Are our current strategies failing, and are their other options? Maybe new targets are needed. Read it below.
The Flavivirus Non-Structural Protein 5 (NS5): Structure, Functions, and Targeting for Development of Vaccines and Therapeutics
Flaviviruses, including dengue (DENV), Zika (ZIKV), West Nile (WNV), Japanese encephalitis (JEV), yellow fever (YFV), and tick-borne encephalitis (TBEV) viruses, pose a significant global emerging threat. With their potential to cause widespread outbreaks and severe health complications, the development of effective vaccines and antiviral therapeutics is imperative. The flaviviral non-structural protein 5 (NS5) is a highly conserved and multifunctional protein that is crucial for viral replication, and the NS5 protein of many flaviviruses has been shown to be a potent inhibitor of interferon (IFN) signalling. In this review, we discuss the functions of NS5, diverse NS5-mediated strategies adopted by flaviviruses to evade the host antiviral response, and how NS5 can be a target for the development of vaccines and antiviral therapeutics.
www.mdpi.com
October 29, 2024 at 11:41 AM
Our paper and the first from our PhD student talking about the current state of flavivirus vaccines. Are our current strategies failing, and are their other options? Maybe new targets are needed. Read it below.
Very clever way of tricking the immune system into production of extremely specific neutralising antibody against Japanese encephalitis virs by presenting JEV proteins on the surface of an insect virus. Presented today by Connor Scott at Lorne I&I conference @theviin.bsky.social
February 19, 2025 at 6:57 AM
Very clever way of tricking the immune system into production of extremely specific neutralising antibody against Japanese encephalitis virs by presenting JEV proteins on the surface of an insect virus. Presented today by Connor Scott at Lorne I&I conference @theviin.bsky.social
Early but exciting morning today. 6am flight to Melbourne to attend my first Lorne Infection and Immunity Conference by @theviin.bsky.social Looking forward for meeting my colleagues from all fields of microbiology and immunology
February 18, 2025 at 8:24 PM
Early but exciting morning today. 6am flight to Melbourne to attend my first Lorne Infection and Immunity Conference by @theviin.bsky.social Looking forward for meeting my colleagues from all fields of microbiology and immunology