Nikolai Slavov
@slavov-n.bsky.social
Mentor, scientist & engineer. Having fun in @slavovlab.bsky.social and Parallel Squared Technology Institute @parallelsq.bsky.social with biology & single-cell proteomics.
https://nikolai.slavovlab.net
https://nikolai.slavovlab.net
... idea that cells use electrochemical gradients as the universal energy currency.
Working largely outside established academic structures, Mitchell and colleagues reimagined oxidative phosphorylation from first principles and reshaped biology and biomedical research for generations to come.
Working largely outside established academic structures, Mitchell and colleagues reimagined oxidative phosphorylation from first principles and reshaped biology and biomedical research for generations to come.
November 27, 2025 at 1:45 PM
... idea that cells use electrochemical gradients as the universal energy currency.
Working largely outside established academic structures, Mitchell and colleagues reimagined oxidative phosphorylation from first principles and reshaped biology and biomedical research for generations to come.
Working largely outside established academic structures, Mitchell and colleagues reimagined oxidative phosphorylation from first principles and reshaped biology and biomedical research for generations to come.
The “research parasite” editorial:
Quote:
" ... people who had nothing to do with the design and execution of the study but use another group’s data for their own ends ... even use the data to try to disprove what the original investigators had posited."
2/2
Quote:
" ... people who had nothing to do with the design and execution of the study but use another group’s data for their own ends ... even use the data to try to disprove what the original investigators had posited."
2/2
November 23, 2025 at 2:59 PM
The “research parasite” editorial:
Quote:
" ... people who had nothing to do with the design and execution of the study but use another group’s data for their own ends ... even use the data to try to disprove what the original investigators had posited."
2/2
Quote:
" ... people who had nothing to do with the design and execution of the study but use another group’s data for their own ends ... even use the data to try to disprove what the original investigators had posited."
2/2
Human tRNA isodecoder pools show substantial interdependence of modifications at distinct sites within the same tRNA transcript.
High-resolution quantitative profiling of tRNA abundance and modification status in eukaryotes by mim-tRNAseq
2/2
www.cell.com/molecular-ce...
High-resolution quantitative profiling of tRNA abundance and modification status in eukaryotes by mim-tRNAseq
2/2
www.cell.com/molecular-ce...
High-resolution quantitative profiling of tRNA abundance and modification status in eukaryotes by mim-tRNAseq
Quantification of tRNAs by sequencing has been hampered by premature RT termination
at modified sites and the extensive sequence similarity among tRNA genes. Behrens
et al. overcome these two key chal...
www.cell.com
November 21, 2025 at 3:29 PM
Human tRNA isodecoder pools show substantial interdependence of modifications at distinct sites within the same tRNA transcript.
High-resolution quantitative profiling of tRNA abundance and modification status in eukaryotes by mim-tRNAseq
2/2
www.cell.com/molecular-ce...
High-resolution quantitative profiling of tRNA abundance and modification status in eukaryotes by mim-tRNAseq
2/2
www.cell.com/molecular-ce...
November 20, 2025 at 12:57 PM
Where is the dislike button ?
November 19, 2025 at 2:00 PM
Where is the dislike button ?
Plans use the air spaces between its cells to scatter light, modifying the path of light passing through its tissues. This creates a light gradient that helps seedlings determine where light is coming from.
quantamagazine.org/plants-find-... via
@quantamagazine.bsky.social
quantamagazine.org/plants-find-... via
@quantamagazine.bsky.social
Plants Find Light Using Gaps Between Their Cells | Quanta Magazine
A mutant seedling revealed how plant tissues scatter incoming light, allowing plants to sense its direction and move toward it.
quantamagazine.org
November 16, 2025 at 12:34 PM
Plans use the air spaces between its cells to scatter light, modifying the path of light passing through its tissues. This creates a light gradient that helps seedlings determine where light is coming from.
quantamagazine.org/plants-find-... via
@quantamagazine.bsky.social
quantamagazine.org/plants-find-... via
@quantamagazine.bsky.social
Sometimes, on simple way of describing the complexity of the data exists, at least not one that humans can readily interpret.
Then, faithfully representing the data is at odds with finding simple explanations.
“𝐸𝑣𝑒𝑟𝑦𝑡ℎ𝑖𝑛𝑔 𝑠ℎ𝑜𝑢𝑙𝑑 𝑏𝑒 𝑚𝑎𝑑𝑒 𝑎𝑠 𝑠𝑖𝑚𝑝𝑙𝑒 𝑎𝑠 𝑝𝑜𝑠𝑠𝑖𝑏𝑙𝑒, 𝑏𝑢𝑡 𝑛𝑜 𝑠𝑖𝑚𝑝𝑙𝑒𝑟”
3/n
Then, faithfully representing the data is at odds with finding simple explanations.
“𝐸𝑣𝑒𝑟𝑦𝑡ℎ𝑖𝑛𝑔 𝑠ℎ𝑜𝑢𝑙𝑑 𝑏𝑒 𝑚𝑎𝑑𝑒 𝑎𝑠 𝑠𝑖𝑚𝑝𝑙𝑒 𝑎𝑠 𝑝𝑜𝑠𝑠𝑖𝑏𝑙𝑒, 𝑏𝑢𝑡 𝑛𝑜 𝑠𝑖𝑚𝑝𝑙𝑒𝑟”
3/n
November 14, 2025 at 12:45 PM
Sometimes, on simple way of describing the complexity of the data exists, at least not one that humans can readily interpret.
Then, faithfully representing the data is at odds with finding simple explanations.
“𝐸𝑣𝑒𝑟𝑦𝑡ℎ𝑖𝑛𝑔 𝑠ℎ𝑜𝑢𝑙𝑑 𝑏𝑒 𝑚𝑎𝑑𝑒 𝑎𝑠 𝑠𝑖𝑚𝑝𝑙𝑒 𝑎𝑠 𝑝𝑜𝑠𝑠𝑖𝑏𝑙𝑒, 𝑏𝑢𝑡 𝑛𝑜 𝑠𝑖𝑚𝑝𝑙𝑒𝑟”
3/n
Then, faithfully representing the data is at odds with finding simple explanations.
“𝐸𝑣𝑒𝑟𝑦𝑡ℎ𝑖𝑛𝑔 𝑠ℎ𝑜𝑢𝑙𝑑 𝑏𝑒 𝑚𝑎𝑑𝑒 𝑎𝑠 𝑠𝑖𝑚𝑝𝑙𝑒 𝑎𝑠 𝑝𝑜𝑠𝑠𝑖𝑏𝑙𝑒, 𝑏𝑢𝑡 𝑛𝑜 𝑠𝑖𝑚𝑝𝑙𝑒𝑟”
3/n
A basic intro with some strategies how to avoid mistakes when using dimensionality reduction.
2/n
youtu.be/nIB-WjWzDSc?...
2/n
youtu.be/nIB-WjWzDSc?...
Introduction to dimensionality reduction | Statistics for proteomics
YouTube video by Nikolai Slavov
youtu.be
November 14, 2025 at 12:45 PM
A basic intro with some strategies how to avoid mistakes when using dimensionality reduction.
2/n
youtu.be/nIB-WjWzDSc?...
2/n
youtu.be/nIB-WjWzDSc?...