Jase Gehring
skyjase.bsky.social
Jase Gehring
@skyjase.bsky.social
scientist at UC Berkeley inventing advanced genomic technologies

lover of molecules, user of computers

https://scholar.google.com/citations?user=63ZRebIAAAAJ&hl=en
Step 1.
November 13, 2025 at 5:18 AM
major scientific impact will require further improvements in capabilities. LLMs lack intuition because they lack physical understanding.

For now, though, it’s nice to have an assistant to talk through things that wouldn’t be worthy of a colleague’s time
November 13, 2025 at 5:03 AM
Challenging science tasks where LLMs excel:

- natural language search
- interactive simulations/artifacts to build physical intuition
- wordsmithing using domain knowledge
- protocol review for experiments
November 13, 2025 at 5:03 AM
These are tasks human experts tackle routinely. They are good examples of human influence in science, and LLMs perform poorly.
November 13, 2025 at 5:03 AM
imo it's a fair critique, mostly because of industry plans to continue to scale aggressively. it's not yet worthy of the same concern as the dirtiest industries, but they're working on it!
November 12, 2025 at 4:32 PM
hyperscalers have greatly expanded datacenter capacity in the last few years to the point where it's a small fraction of overall resource use. they are planning to increase the scale at least 10-fold, making it a major fraction. and GPU compute is more energy intensive than traditional blend
November 12, 2025 at 4:32 PM
✨decant✨
November 11, 2025 at 7:51 PM
@jamellebouie.net talks about a revival of civic responsibility, which goes hand in hand. your occupation is your biggest civic contribution, and you should think of it that way. it won't work if everyone spends 40 hrs/wk screwing each other over and 2 hrs/wk volunteering.
November 10, 2025 at 8:07 PM
anti-social industries pay you a premium to ignore ghastly shit, meaning there's effectively a tax on pro-social labor. while that genuinely sucks, it's still your choice what to do.
November 10, 2025 at 8:07 PM
here i was naively thinking that LLMs would help bureaucracy work well, making it easier to maneuver complex regulations. not so fast, i hadn't considered the "be a bigger barrier to progress" side of the equation
November 10, 2025 at 6:58 PM
I think the comparison is useful and I’m worried about how much is being bet on future capabilities of a single industry.
November 5, 2025 at 8:44 PM
Moissanite! Carborundum! the hard stuff
November 5, 2025 at 5:01 PM
dissecting a cow eye and getting a load of the lens was a formative experience for me

enjoy the eyeballs
November 4, 2025 at 10:30 PM
.. confidently provides wrong answers, and generally lacks deep understanding

that's the opposite of what we expect from people, so we assume corresponding intelligence commensurate with capabilities. but that's just not the case.
November 4, 2025 at 3:24 PM