Shicheng Guo
@shihcheng.bsky.social
Senior Director, Translational Genetics and Data Science, Translational Medicine | Data Science | Computational Biology | Drug Discovery | Passionate about advancing genomics and biobank research through collaboration. Opinions are my own!
Wishing everyone a wonderful holiday season! I’m grateful for your support this year and excited to apply for an ASHG 2026 committee role. In 2026, I’ll keep sharing key genomics insights, RNA advances, and opportunities to collaborate. Thanks for being here! Please show your support! Thanks.
November 27, 2025 at 3:56 AM
Wishing everyone a wonderful holiday season! I’m grateful for your support this year and excited to apply for an ASHG 2026 committee role. In 2026, I’ll keep sharing key genomics insights, RNA advances, and opportunities to collaborate. Thanks for being here! Please show your support! Thanks.
Why is it still so hard for Microsoft to make Planner, To Do, and Outlook Calendar actually work together? It’s 2025 — these tools should auto-sync tasks and deadlines seamlessly across functions. Instead, users still juggle disconnected lists. Where’s the unified experience ? @microsoft.com
November 14, 2025 at 8:10 PM
Why is it still so hard for Microsoft to make Planner, To Do, and Outlook Calendar actually work together? It’s 2025 — these tools should auto-sync tasks and deadlines seamlessly across functions. Instead, users still juggle disconnected lists. Where’s the unified experience ? @microsoft.com
Just submitted my application to join an ASHG committee — excited for the chance to contribute to our human genetics community and help shape its future. Hope to hear back soon! I also encourage more colleagues to apply and make your contribution! #ASHG #Genomics @geneticssociety.bsky.social
November 10, 2025 at 5:48 AM
Just submitted my application to join an ASHG committee — excited for the chance to contribute to our human genetics community and help shape its future. Hope to hear back soon! I also encourage more colleagues to apply and make your contribution! #ASHG #Genomics @geneticssociety.bsky.social
I’m attending #ASHG2025 in Boston this week! Excited to connect with researchers and innovators in genetics, drug target identification, and clinical development. I’ll be here until Saturday — let’s meet and explore collaboration opportunities!
#Genomics #DrugDiscovery #RNAi #siRNA
#Genomics #DrugDiscovery #RNAi #siRNA
October 16, 2025 at 9:12 PM
I’m attending #ASHG2025 in Boston this week! Excited to connect with researchers and innovators in genetics, drug target identification, and clinical development. I’ll be here until Saturday — let’s meet and explore collaboration opportunities!
#Genomics #DrugDiscovery #RNAi #siRNA
#Genomics #DrugDiscovery #RNAi #siRNA
Jane Goodall (1934–2025), the world’s most beloved primatologist and tireless voice for our planet, has left us at 91. From the forests of Gombe to global stages, she redefined humanity’s bond with nature and inspired generations to act with hope. Her legacy will keep running.
October 2, 2025 at 2:40 AM
Jane Goodall (1934–2025), the world’s most beloved primatologist and tireless voice for our planet, has left us at 91. From the forests of Gombe to global stages, she redefined humanity’s bond with nature and inspired generations to act with hope. Her legacy will keep running.
I’m excited to attend the American Society of Human Genetics (ASHG) 2025 Annual Meeting in Boston, October 13–18! If you’ll be at ASHG and are interested in exploring collaboration or sharing perspectives, I’d be delighted to meet—feel free to reach out and let’s connect in Boston!
September 27, 2025 at 4:28 AM
I’m excited to attend the American Society of Human Genetics (ASHG) 2025 Annual Meeting in Boston, October 13–18! If you’ll be at ASHG and are interested in exploring collaboration or sharing perspectives, I’d be delighted to meet—feel free to reach out and let’s connect in Boston!
The 2025 BioPacific Conference, the flagship event of CABS, will take place on September 13 at the South San Francisco Convention Center, bringing together global leaders in life sciences to explore breakthroughs in oncology, neurogenetics, antibody-drug conjugates, and AI-driven drug discovery.
September 6, 2025 at 11:13 PM
The 2025 BioPacific Conference, the flagship event of CABS, will take place on September 13 at the South San Francisco Convention Center, bringing together global leaders in life sciences to explore breakthroughs in oncology, neurogenetics, antibody-drug conjugates, and AI-driven drug discovery.
Happy #RNADay! Celebrating the remarkable women shaping the future of RNA therapeutics in the RNA Leaders Women in RNA e-book. Inspiring voices advancing #RNAScience and #BiotechLeadership.
August 24, 2025 at 7:30 PM
Happy #RNADay! Celebrating the remarkable women shaping the future of RNA therapeutics in the RNA Leaders Women in RNA e-book. Inspiring voices advancing #RNAScience and #BiotechLeadership.
Found a great place to buy authentic Asian food online 🍜🥢
Fresh produce, sauces, and snacks all in one place — delivered fast.
Highly recommend checking out Weee! if you love cooking at home.
#AsianFood #Weee #HomeCooking #Foodie #FreshEats #AsianGroceries #FoodLovers #CookingAtHome #HealthyEats
Fresh produce, sauces, and snacks all in one place — delivered fast.
Highly recommend checking out Weee! if you love cooking at home.
#AsianFood #Weee #HomeCooking #Foodie #FreshEats #AsianGroceries #FoodLovers #CookingAtHome #HealthyEats
August 23, 2025 at 4:43 PM
Found a great place to buy authentic Asian food online 🍜🥢
Fresh produce, sauces, and snacks all in one place — delivered fast.
Highly recommend checking out Weee! if you love cooking at home.
#AsianFood #Weee #HomeCooking #Foodie #FreshEats #AsianGroceries #FoodLovers #CookingAtHome #HealthyEats
Fresh produce, sauces, and snacks all in one place — delivered fast.
Highly recommend checking out Weee! if you love cooking at home.
#AsianFood #Weee #HomeCooking #Foodie #FreshEats #AsianGroceries #FoodLovers #CookingAtHome #HealthyEats
Do you have version 2025? I can only find 2023 version.
July 27, 2025 at 5:08 AM
Do you have version 2025? I can only find 2023 version.
Genomics England Research Summit on Tuesday 17 June 2025, from 8:45am- 6:45pm.
genomicsresearchsummit.co.uk/agenda2025
genomicsresearchsummit.co.uk/agenda2025
June 10, 2025 at 6:56 PM
Genomics England Research Summit on Tuesday 17 June 2025, from 8:45am- 6:45pm.
genomicsresearchsummit.co.uk/agenda2025
genomicsresearchsummit.co.uk/agenda2025
Incredible work by the MedHELM team! This framework sets a new gold standard for evaluating LLMs in clinical and healthcare contexts—deeply impressed by the rigor, breadth, and real-world relevance of the 121 clinical tasks and 35 benchmarks. #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
June 10, 2025 at 6:40 PM
🚨 Pioneering Disease-Modifying Therapies for Ischemic Heart Disease. 🔬 Patricia Nguyen, MD – Associate Professor of Medicine (Cardiovascular Medicine), Stanford University
👏 Fantastic work leading the shift from symptom management to true disease modification.
#Cardiology #StanfordMed
👏 Fantastic work leading the shift from symptom management to true disease modification.
#Cardiology #StanfordMed
June 3, 2025 at 8:02 PM
🚨 Pioneering Disease-Modifying Therapies for Ischemic Heart Disease. 🔬 Patricia Nguyen, MD – Associate Professor of Medicine (Cardiovascular Medicine), Stanford University
👏 Fantastic work leading the shift from symptom management to true disease modification.
#Cardiology #StanfordMed
👏 Fantastic work leading the shift from symptom management to true disease modification.
#Cardiology #StanfordMed
🧭 From data density to prediction modeling, ATLAS has come a long way!
📈 The Atlas 2.x timeline (2017–2023) shows 300+ issues closed, major feature releases, and global impact.
Explore the power behind #OHDSI’s open-source analytics platform.
#Rstats #HealthData #RealWorldEvidence
📈 The Atlas 2.x timeline (2017–2023) shows 300+ issues closed, major feature releases, and global impact.
Explore the power behind #OHDSI’s open-source analytics platform.
#Rstats #HealthData #RealWorldEvidence
June 3, 2025 at 3:32 PM
🧭 From data density to prediction modeling, ATLAS has come a long way!
📈 The Atlas 2.x timeline (2017–2023) shows 300+ issues closed, major feature releases, and global impact.
Explore the power behind #OHDSI’s open-source analytics platform.
#Rstats #HealthData #RealWorldEvidence
📈 The Atlas 2.x timeline (2017–2023) shows 300+ issues closed, major feature releases, and global impact.
Explore the power behind #OHDSI’s open-source analytics platform.
#Rstats #HealthData #RealWorldEvidence
🚀 The Atlas 2.x journey from 2.0 (2017) to 2.14 (2023) shows 7 years of relentless progress in open-source health data science. From Operation Bugfix to multi-language localization, asset versioning & audit trails—300+ issues crushed along the way. #OHDSI #Rstats #HealthTech
June 3, 2025 at 3:22 PM
🚀 The Atlas 2.x journey from 2.0 (2017) to 2.14 (2023) shows 7 years of relentless progress in open-source health data science. From Operation Bugfix to multi-language localization, asset versioning & audit trails—300+ issues crushed along the way. #OHDSI #Rstats #HealthTech
🚨 New from Stanford & Genmab: UniTox uses GPT-4o to extract drug-induced toxicities from 2,400+ FDA labels into a structured dataset. Human-in-the-loop + LLMs = scalable, validated pharmacovigilance. Impressive use of AI in drug safety! #AI #DrugSafety #GPT4o 🧪
May 24, 2025 at 4:51 AM
🚨 New from Stanford & Genmab: UniTox uses GPT-4o to extract drug-induced toxicities from 2,400+ FDA labels into a structured dataset. Human-in-the-loop + LLMs = scalable, validated pharmacovigilance. Impressive use of AI in drug safety! #AI #DrugSafety #GPT4o 🧪
New gene engineering frontier: Dr. Howard Wu @ Full Circles Therapeutics unveils a viral-free platform using circular ssDNA (cssDNA) for high-efficiency genome integration (up to 70%) in CAR-T/NK cells. Goodbye viruses, hello scalable cell therapy. #GeneEditing #CGM497🧪
May 24, 2025 at 1:59 AM
New gene engineering frontier: Dr. Howard Wu @ Full Circles Therapeutics unveils a viral-free platform using circular ssDNA (cssDNA) for high-efficiency genome integration (up to 70%) in CAR-T/NK cells. Goodbye viruses, hello scalable cell therapy. #GeneEditing #CGM497🧪
Incredible lineup and topic! Dr. Jimeng Sun’s work on generative digital twins addresses some of the most pressing challenges in clinical AI—bias, data privacy, and missingness—by synthesizing realistic, multi-modal patient data. Excited to learn how tools like HALO, ConSequence, and MRI2PET🧪
May 22, 2025 at 12:45 AM
Incredible lineup and topic! Dr. Jimeng Sun’s work on generative digital twins addresses some of the most pressing challenges in clinical AI—bias, data privacy, and missingness—by synthesizing realistic, multi-modal patient data. Excited to learn how tools like HALO, ConSequence, and MRI2PET🧪
Dr. James Hickman shared groundbreaking work at
@stanfordcvi.bsky.social on multi-organ human platforms for drug testing—bridging preclinical and clinical gaps with cardiac, liver, and neural mimics. A major step toward predictive, AI-integrated translational models. #AI #drug #organ
@stanfordcvi.bsky.social on multi-organ human platforms for drug testing—bridging preclinical and clinical gaps with cardiac, liver, and neural mimics. A major step toward predictive, AI-integrated translational models. #AI #drug #organ
May 21, 2025 at 12:12 AM
Dr. James Hickman shared groundbreaking work at
@stanfordcvi.bsky.social on multi-organ human platforms for drug testing—bridging preclinical and clinical gaps with cardiac, liver, and neural mimics. A major step toward predictive, AI-integrated translational models. #AI #drug #organ
@stanfordcvi.bsky.social on multi-organ human platforms for drug testing—bridging preclinical and clinical gaps with cardiac, liver, and neural mimics. A major step toward predictive, AI-integrated translational models. #AI #drug #organ
Incredible talk by Dr. Hund on how the heart remodels under stress.
Key takeaway: βIV-spectrin–CAMKII–STAT3 complex acts as a molecular switchboard for adaptive vs. maladaptive hypertrophy.
Block it too early after MI? Fatal. Block it in pressure overload? Protective. Context is everything. 🧪
Key takeaway: βIV-spectrin–CAMKII–STAT3 complex acts as a molecular switchboard for adaptive vs. maladaptive hypertrophy.
Block it too early after MI? Fatal. Block it in pressure overload? Protective. Context is everything. 🧪
May 13, 2025 at 9:04 PM
Incredible talk by Dr. Hund on how the heart remodels under stress.
Key takeaway: βIV-spectrin–CAMKII–STAT3 complex acts as a molecular switchboard for adaptive vs. maladaptive hypertrophy.
Block it too early after MI? Fatal. Block it in pressure overload? Protective. Context is everything. 🧪
Key takeaway: βIV-spectrin–CAMKII–STAT3 complex acts as a molecular switchboard for adaptive vs. maladaptive hypertrophy.
Block it too early after MI? Fatal. Block it in pressure overload? Protective. Context is everything. 🧪