Shai Carmi
shaicarmi.bsky.social
Shai Carmi
@shaicarmi.bsky.social
Associate professor at the Hebrew University of Jerusalem.
Statistical, population, and medical genetics; preimplantation genetic testing. Views my own.
http://scarmilab.org
I agree, but I think this is why we should limit the number of children a single donor can father.

I'm not worried about not having enough (sperm) donors. I think it's just a matter of paying more.
December 10, 2025 at 7:28 PM
As far as I know, in the UK it is illegal to select embryos based on genetic data except for a list of conditions prespecified by the HFEA (the regulatory body for assisted reproduction).
Whether this is enforceable is of course another question.
December 8, 2025 at 7:04 AM
Reposted by Shai Carmi
This comment made me wonder: what kinds of cases or research goals/questions would geneticists generally consider scientifically useful/interesting/valid when it comes to looking at the genomes of long-dead famous people?
November 17, 2025 at 10:01 AM
By the way, how is it possible to watch the actual documentary? (Outside the UK)
November 15, 2025 at 5:48 AM
I'm not generally against sequencing "named" individuals. E.g. Work on Beethoven's genome has been reasonable and interesting.

This particular case is shameful because the underlying narrative is that the Holocaust and other horrors could be explained by a bad gene.
November 15, 2025 at 5:32 AM
Right. Also, the distribution of any PRS in Austrians may differ from that of Danes.

But these details (which may appear in a future publication) are technical. Doing this project and analysis in the first place is much more disturbing.
November 14, 2025 at 1:12 PM
3. From what's been reported so far, it seems that the important values of engagement with the community/victims/their descendants unfortunately don't apply to all human populations.
November 14, 2025 at 9:13 AM
I generally agree, although the lead researcher in this case is usually reliable.
November 13, 2025 at 1:53 PM
Overall, nothing new or entirely unexpected, but I think evidence is starting to mount that PRS are not too clinically useful the way they are currently marketed by researchers and companies.
November 7, 2025 at 8:33 AM