Drew Schreiner
@schreinerdrew.bsky.social
learning | neuroethology | basal ganglia | birdsong | decision-making | natural history | Current K99 Postdoc Rich Mooney @Duke | PhD Christina Gremel @UC San Diego
Pinned
Drew Schreiner
@schreinerdrew.bsky.social
· Mar 12
Dual neuromodulatory dynamics underlie birdsong learning - Nature
Dopamine release in the basal ganglia of the zebra finch is driven by neurons associated with reinforcement learning and by cholinergic signalling, and tracks performance quality during long-term lear...
www.nature.com
Proud to have contributed to @jiaxuanqi.bsky.social's masterpiece out @nature.com! She shows that dopamine transients track the learned quality of song during juvenile learning and that dopamine release is driven not just by VTA firing, but by a local cholinergic mechanism! (1/x)
Reposted by Drew Schreiner
November 17, 2025 at 1:15 AM
Reposted by Drew Schreiner
I am not at SFN this year but my dopamine friends are asking you to come out and celebrate the worlds best precursor molecule.
November 16, 2025 at 7:31 PM
I am not at SFN this year but my dopamine friends are asking you to come out and celebrate the worlds best precursor molecule.
Conferences, or whatever your professional domain’s equivalent communal gathering happens to be, are a fundamentally load-bearing aspect of building anything worthwhile at scale. Just excellent to feel like one amidst a host of likeminded people largely pulling in the same direction.
November 16, 2025 at 6:39 AM
Reposted by Drew Schreiner
Excited to present our recent work at #SfN25 's Evolutionary Neurogenomics session this Tuesday!
🧬 Evolution meets neuroscience at #SfN25!
Learn how multi-omics approaches are revealing how evolution acts on cell types, underpinning neural circuitry and behavior changes across diverse species.
📅 Tues., 11/18, 9:30am–12:00pm
📍 Rm 6CF
📲 https://www.abstractsonline.com/pp8/#!/21171/session/1213
Learn how multi-omics approaches are revealing how evolution acts on cell types, underpinning neural circuitry and behavior changes across diverse species.
📅 Tues., 11/18, 9:30am–12:00pm
📍 Rm 6CF
📲 https://www.abstractsonline.com/pp8/#!/21171/session/1213
November 16, 2025 at 5:14 AM
Excited to present our recent work at #SfN25 's Evolutionary Neurogenomics session this Tuesday!
Reposted by Drew Schreiner
I am very grateful for Steve's leadership and excited to step into this new role! www.neuro.duke.edu/news/lisberg...
Lisberger to step down as department chair; Bilbo named interim leader
Stephen Lisberger, PhD, George Barth Geller Distinguished Professor for Research in Neurobiology, will step down from his role as
www.neuro.duke.edu
November 15, 2025 at 7:41 PM
I am very grateful for Steve's leadership and excited to step into this new role! www.neuro.duke.edu/news/lisberg...
In birdsong, it's definitely "HVC (used as a proper name)"
What other seemingly obligatory phrases do you notice in neuro papers?
November 14, 2025 at 8:35 PM
In birdsong, it's definitely "HVC (used as a proper name)"
Reposted by Drew Schreiner
My first official post to say see you at #SfN2025! I'm presenting some new ephys work with @healeylab.bsky.social looking at auditory responses to chick calls in zebra finch parents! 🐦🧠🔊🐣 Tuesday @ 2pm (PSTR346, Vocal/Social Communication). ALSO ~ my lab is opening soon and we're HIRING!! (see ⬇️)
November 14, 2025 at 7:49 PM
My first official post to say see you at #SfN2025! I'm presenting some new ephys work with @healeylab.bsky.social looking at auditory responses to chick calls in zebra finch parents! 🐦🧠🔊🐣 Tuesday @ 2pm (PSTR346, Vocal/Social Communication). ALSO ~ my lab is opening soon and we're HIRING!! (see ⬇️)
Reposted by Drew Schreiner
Welcome to SFN !!! @julielefebvrelab.bsky.social and I will be hosting the "Bridging the Synapse" networking event on Monday 11/17 at the Marriott at 7 PM! Come hang out with synaptic biologists from all over to talk about the coolest topics in neuroscience with the coolest folk! Spread the word!
November 14, 2025 at 4:43 PM
Welcome to SFN !!! @julielefebvrelab.bsky.social and I will be hosting the "Bridging the Synapse" networking event on Monday 11/17 at the Marriott at 7 PM! Come hang out with synaptic biologists from all over to talk about the coolest topics in neuroscience with the coolest folk! Spread the word!
More details: Come hear about my work isolating a corticostriatal locus of birdsong learning - and how I leveraged this localization to make birds learn faster! #SfN25
Early Career TPDA Poster session: Sat. night 6:45-8:45pm, poster H6
and
Mon. Morning, poster V6
Early Career TPDA Poster session: Sat. night 6:45-8:45pm, poster H6
and
Mon. Morning, poster V6
November 14, 2025 at 4:12 PM
More details: Come hear about my work isolating a corticostriatal locus of birdsong learning - and how I leveraged this localization to make birds learn faster! #SfN25
Early Career TPDA Poster session: Sat. night 6:45-8:45pm, poster H6
and
Mon. Morning, poster V6
Early Career TPDA Poster session: Sat. night 6:45-8:45pm, poster H6
and
Mon. Morning, poster V6
Reposted by Drew Schreiner
This work is so, so good. Really elegant demonstration of why low-dimensional neural dynamics in movement may follow from simple control principles. Highly complementary to arguments from Peiran Gao and @suryaganguli.bsky.social.
Fred Crevecoeur
@fredericcrevec1
🚨preprint time by @harikalidindi.bsky.social
for our work on neural population dynamics: we show that features of neural population activity during reaching emerge from a simple linear body-network system 🧵👇
biorxiv.org/content/10.1...
@fredericcrevec1
🚨preprint time by @harikalidindi.bsky.social
for our work on neural population dynamics: we show that features of neural population activity during reaching emerge from a simple linear body-network system 🧵👇
biorxiv.org/content/10.1...
November 13, 2025 at 7:35 PM
This work is so, so good. Really elegant demonstration of why low-dimensional neural dynamics in movement may follow from simple control principles. Highly complementary to arguments from Peiran Gao and @suryaganguli.bsky.social.
Reposted by Drew Schreiner
Foraging as an ethological framework for neuroscience
From the amazing @lauragrima.bsky.social and colleagues - definitely looking forward to reading this!
#neuroskyence #psychscisky #cognition
From the amazing @lauragrima.bsky.social and colleagues - definitely looking forward to reading this!
#neuroskyence #psychscisky #cognition
Foraging as an ethological framework for neuroscience
The study of foraging is central to a renewed interest in naturalistic behavior in neuroscience. Applying a foraging framework grounded in behavioral …
www.sciencedirect.com
November 14, 2025 at 9:23 AM
Foraging as an ethological framework for neuroscience
From the amazing @lauragrima.bsky.social and colleagues - definitely looking forward to reading this!
#neuroskyence #psychscisky #cognition
From the amazing @lauragrima.bsky.social and colleagues - definitely looking forward to reading this!
#neuroskyence #psychscisky #cognition
Incubation of craving is real: took me less than 45 mins after touchdown in San Diego to get the first California Burrito
November 13, 2025 at 10:06 PM
Incubation of craving is real: took me less than 45 mins after touchdown in San Diego to get the first California Burrito
Reposted by Drew Schreiner
I'll be presenting a poster on this at SFN on Monday morning, poster QQ5. Come say hi!
Looking forward to hearing about all the great science everyone's been doing!
Looking forward to hearing about all the great science everyone's been doing!
🚨Our preprint is online!🚨
www.biorxiv.org/content/10.1...
How do #dopamine neurons perform the key calculations in reinforcement #learning?
Read on to find out more! 🧵
www.biorxiv.org/content/10.1...
How do #dopamine neurons perform the key calculations in reinforcement #learning?
Read on to find out more! 🧵
November 13, 2025 at 6:48 PM
I'll be presenting a poster on this at SFN on Monday morning, poster QQ5. Come say hi!
Looking forward to hearing about all the great science everyone's been doing!
Looking forward to hearing about all the great science everyone's been doing!
Reposted by Drew Schreiner
Finally out! If you are interested in implementing closed loop experiments but need the flexibility to roll your own real-time algorithms, we can save you some serious time.
Our new paper in @natcomms.nature.com introduces improv, a flexible software platform that integrates models with experiments in real-time. Traditional experiments collect all data first, then analyze it later. With improv, models analyze data as it streams in and actively guide what to do next.
November 13, 2025 at 3:53 PM
Finally out! If you are interested in implementing closed loop experiments but need the flexibility to roll your own real-time algorithms, we can save you some serious time.
Reposted by Drew Schreiner
November 13, 2025 at 10:24 AM
Reposted by Drew Schreiner
The Gowrishankar lab will be opening its doors @neuro_MUSC on Dec 1, 2025! We will be hiring at all levels. I will also be at @SfNtweets presenting my lab's vision on Wednesday, Nov 19, 8AM-12PM at poster board GG7. If you're interested, please reach out!
www.raajgowrishankarlab.org
www.raajgowrishankarlab.org
Gowrishankar Lab
www.raajgowrishankarlab.org
November 12, 2025 at 10:23 PM
The Gowrishankar lab will be opening its doors @neuro_MUSC on Dec 1, 2025! We will be hiring at all levels. I will also be at @SfNtweets presenting my lab's vision on Wednesday, Nov 19, 8AM-12PM at poster board GG7. If you're interested, please reach out!
www.raajgowrishankarlab.org
www.raajgowrishankarlab.org
Reposted by Drew Schreiner
Thrilled to share our new paper, out now in @natneuro.nature.com, uncovering how estradiol, the most potent estrogen, modulates reinforcement learning and reward prediction errors across biological levels. www.nature.com/articles/s41...
#blueprint 1/7
#blueprint 1/7
Estrogen modulates reward prediction errors and reinforcement learning - Nature Neuroscience
Dopamine encoding of reward prediction errors naturally fluctuates over females’ reproductive cycles with estrogenic signaling due to reduced expression of dopamine reuptake proteins.
www.nature.com
November 11, 2025 at 2:41 PM
Thrilled to share our new paper, out now in @natneuro.nature.com, uncovering how estradiol, the most potent estrogen, modulates reinforcement learning and reward prediction errors across biological levels. www.nature.com/articles/s41...
#blueprint 1/7
#blueprint 1/7
Reposted by Drew Schreiner
Delighted to see this finally out: rdcu.be/eO9oW
We tested whether brief striatal dopamine release events influence the vigor of skilled movements. Despite popular belief, we did not find any evidence linking rapid dopamine dynamics to motor vigor on a moment-by-moment basis.
We tested whether brief striatal dopamine release events influence the vigor of skilled movements. Despite popular belief, we did not find any evidence linking rapid dopamine dynamics to motor vigor on a moment-by-moment basis.
Subsecond dopamine fluctuations do not specify the vigor of ongoing actions
Nature Neuroscience - Liu and colleagues show that the vigor (that is, speed and amplitude) of dexterous movements is not controlled by ongoing fluctuations in extracellular dopamine within the...
rdcu.be
November 10, 2025 at 3:43 PM
Delighted to see this finally out: rdcu.be/eO9oW
We tested whether brief striatal dopamine release events influence the vigor of skilled movements. Despite popular belief, we did not find any evidence linking rapid dopamine dynamics to motor vigor on a moment-by-moment basis.
We tested whether brief striatal dopamine release events influence the vigor of skilled movements. Despite popular belief, we did not find any evidence linking rapid dopamine dynamics to motor vigor on a moment-by-moment basis.
Reposted by Drew Schreiner
To truly understand the neurobiological basis of complex behaviors - the real 𝐦𝐞𝐚𝐧𝐢𝐧𝐠 𝐨𝐟 𝐥𝐢𝐟𝐞, 𝐭𝐡𝐞 𝐮𝐧𝐢𝐯𝐞𝐫𝐬𝐞, 𝐚𝐧𝐝 𝐞𝐯𝐞𝐫𝐲𝐭𝐡𝐢𝐧𝐠 - we must overcome the limitations of traditional, short-term behavioral tests.
November 10, 2025 at 2:54 PM
To truly understand the neurobiological basis of complex behaviors - the real 𝐦𝐞𝐚𝐧𝐢𝐧𝐠 𝐨𝐟 𝐥𝐢𝐟𝐞, 𝐭𝐡𝐞 𝐮𝐧𝐢𝐯𝐞𝐫𝐬𝐞, 𝐚𝐧𝐝 𝐞𝐯𝐞𝐫𝐲𝐭𝐡𝐢𝐧𝐠 - we must overcome the limitations of traditional, short-term behavioral tests.
The Eno (Durham, left) and the Neckar (Tuebingen, right) rivers taken ~12 hrs apart
November 10, 2025 at 1:25 PM
The Eno (Durham, left) and the Neckar (Tuebingen, right) rivers taken ~12 hrs apart
Reposted by Drew Schreiner
Shared cognitive biases influence numerical judgments in macaques and crows @PNAS.org
Shared cognitive biases influence numerical judgments in macaques and crows
Proceedings of the National Academy of Sciences, Volume 122, Issue 44, November 2025.
SignificanceCognitive biases, often seen as uniquely human flaws, may instead reflect fundamental decision-making strategies shared across species. By demonstrating that macaque monkeys and carrion crows exhibit human-like biases in numerical estimation—...
dlvr.it
November 8, 2025 at 9:24 AM
Shared cognitive biases influence numerical judgments in macaques and crows @PNAS.org
Reposted by Drew Schreiner
How do VTA DA neurons sculpt downstream representations to reinforce actions? VERY excited about our new preprint (by Alex Pan Vazquez & @czimmerman.bsky.social )
VTA dopamine neuron activity produces spatially organized value representations https://www.biorxiv.org/content/10.1101/2025.11.04.685995v1
November 7, 2025 at 8:46 PM
How do VTA DA neurons sculpt downstream representations to reinforce actions? VERY excited about our new preprint (by Alex Pan Vazquez & @czimmerman.bsky.social )
NINDS was going to host a get together for K99/R00 fellows that I was really looking forward to.
We could try to re-create it if enough folks are interested? Feel free to reach out to me
We could try to re-create it if enough folks are interested? Feel free to reach out to me
Sigh. NIH normally sends several hundred scientists to the SFN annual meeting to learn, exchange info, come up with new ideas, and advance science. (The exchange of ideas is the very core of the scientific enterprise.)
This year, no one from NIH will attend due to the gov't implosion.
This year, no one from NIH will attend due to the gov't implosion.
Enjoy a broad range of lectures and network with experts in the field at #SfN25! 🧠
Gain valuable insights and tools to enhance your research and career.
Browse through to lectures and build your itinerary in the 2025 Neuroscience Meeting Planner
🔗 vist.ly/4de72
#neurosky #neuroskyence
Gain valuable insights and tools to enhance your research and career.
Browse through to lectures and build your itinerary in the 2025 Neuroscience Meeting Planner
🔗 vist.ly/4de72
#neurosky #neuroskyence
November 7, 2025 at 11:22 PM
NINDS was going to host a get together for K99/R00 fellows that I was really looking forward to.
We could try to re-create it if enough folks are interested? Feel free to reach out to me
We could try to re-create it if enough folks are interested? Feel free to reach out to me